Article ; Online: Infantile Pyknocytosis: End-Tidal CO, %Micro-R Measurements, Next-Generation Sequencing, and Transfusion Avoidance with Darbepoetin.
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2020 Volume 5, Issue 3, Page(s) 227–234
Abstract: Infantile pyknocytosis is a rare, self-limited, hemolytic condition of unknown pathogenesis. It is diagnosed when a neonate with Coombs-negative hemolytic anemia has abundant pyknocytes and a characteristic clinical course after other hemolytic disorders ...
Abstract | Infantile pyknocytosis is a rare, self-limited, hemolytic condition of unknown pathogenesis. It is diagnosed when a neonate with Coombs-negative hemolytic anemia has abundant pyknocytes and a characteristic clinical course after other hemolytic disorders has been excluded. Previous reports suggest that transfusions might be avoidable in this condition by administering recombinant erythropoietin. We cared for a patient with this disorder where we employed novel diagnostics and therapeutics. Despite these, and a good outcome free of transfusions, we continue to consider the condition to be idiopathic. |
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Language | English |
Publishing date | 2020-12-11 |
Publishing country | Switzerland |
Document type | Case Reports |
ISSN | 2296-6870 |
ISSN (online) | 2296-6870 |
DOI | 10.1159/000511388 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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