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  1. Article ; Online: Reply to A Letter Concerning "Aducanumab: What About the Patient?"

    Petersen, Ronald C

    Annals of neurology

    2022  Volume 91, Issue 5, Page(s) 733–734

    Language English
    Publishing date 2022-03-28
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 80362-5
    ISSN 1531-8249 ; 0364-5134
    ISSN (online) 1531-8249
    ISSN 0364-5134
    DOI 10.1002/ana.26344
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1370: Show issues Location:
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    Zs.MO 478: Show issues

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  2. Article ; Online: Detecting Alzheimer Disease Clinically: How Early Can We Go?

    Petersen, Ronald C

    Neurology

    2022  Volume 98, Issue 15, Page(s) 607–608

    MeSH term(s) Alzheimer Disease/diagnosis ; Brain ; Humans
    Language English
    Publishing date 2022-03-25
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 207147-2
    ISSN 1526-632X ; 0028-3878
    ISSN (online) 1526-632X
    ISSN 0028-3878
    DOI 10.1212/WNL.0000000000200172
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ui II Zs.153: Show issues Location:
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    Zs.MO 374: Show issues

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  3. Article ; Online: Are plasma markers for Alzheimer's disease ready for clinical use?

    Petersen, Ronald C

    Nature aging

    2022  Volume 2, Issue 2, Page(s) 94–96

    MeSH term(s) Humans ; Alzheimer Disease/diagnosis ; Amyloid beta-Peptides ; Biomarkers
    Chemical Substances Amyloid beta-Peptides ; Biomarkers
    Language English
    Publishing date 2022-04-18
    Publishing country United States
    Document type Journal Article
    ISSN 2662-8465
    ISSN (online) 2662-8465
    DOI 10.1038/s43587-022-00176-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: MCI Criteria in ADNI: Meeting Biological Expectations.

    Petersen, Ronald C

    Neurology

    2021  Volume 97, Issue 12, Page(s) 597–599

    Language English
    Publishing date 2021-09-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 207147-2
    ISSN 1526-632X ; 0028-3878
    ISSN (online) 1526-632X
    ISSN 0028-3878
    DOI 10.1212/WNL.0000000000012588
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Aducanumab: What about the Patient?

    Petersen, Ronald C

    Annals of neurology

    2021  Volume 90, Issue 3, Page(s) 334–335

    MeSH term(s) Aged ; Alzheimer Disease/drug therapy ; Alzheimer Disease/psychology ; Antibodies, Monoclonal, Humanized/therapeutic use ; Clinical Decision-Making/methods ; Drug Approval/methods ; Humans
    Chemical Substances Antibodies, Monoclonal, Humanized ; aducanumab (105J35OE21)
    Language English
    Publishing date 2021-08-07
    Publishing country United States
    Document type Editorial ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 80362-5
    ISSN 1531-8249 ; 0364-5134
    ISSN (online) 1531-8249
    ISSN 0364-5134
    DOI 10.1002/ana.26181
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Jg. 1995 - 2021: Lesesall (1.OG)
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    Zs.MO 478: Show issues

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  6. Article ; Online: Reply to "Thinking beyond Aducanumab Controversy".

    C Petersen, Ronald

    Annals of neurology

    2021  Volume 90, Issue 6, Page(s) 1004

    MeSH term(s) Amyloid beta-Peptides ; Antibodies, Monoclonal, Humanized ; Humans
    Chemical Substances Amyloid beta-Peptides ; Antibodies, Monoclonal, Humanized ; aducanumab (105J35OE21)
    Language English
    Publishing date 2021-11-06
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 80362-5
    ISSN 1531-8249 ; 0364-5134
    ISSN (online) 1531-8249
    ISSN 0364-5134
    DOI 10.1002/ana.26253
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1370: Show issues Location:
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    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 478: Show issues

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  7. Article ; Online: Issues and Questions Surrounding Screening for Cognitive Impairment in Older Patients.

    Petersen, Ronald C / Yaffe, Kristine

    JAMA

    2020  Volume 323, Issue 8, Page(s) 722–724

    MeSH term(s) Advisory Committees ; Aged ; Cognition Disorders ; Cognitive Dysfunction ; Humans ; Mass Screening
    Language English
    Publishing date 2020-01-20
    Publishing country United States
    Document type Editorial ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 2958-0
    ISSN 1538-3598 ; 0254-9077 ; 0002-9955 ; 0098-7484
    ISSN (online) 1538-3598
    ISSN 0254-9077 ; 0002-9955 ; 0098-7484
    DOI 10.1001/jama.2019.22527
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: The quest for dementia prevention does not include an aspirin a day.

    Knopman, David S / Petersen, Ronald C

    Neurology

    2020  Volume 95, Issue 3, Page(s) 105–106

    MeSH term(s) Aspirin ; Cognitive Dysfunction ; Dementia, Vascular ; Humans
    Chemical Substances Aspirin (R16CO5Y76E)
    Language English
    Publishing date 2020-03-25
    Publishing country United States
    Document type Editorial ; Research Support, N.I.H., Extramural ; Comment
    ZDB-ID 207147-2
    ISSN 1526-632X ; 0028-3878
    ISSN (online) 1526-632X
    ISSN 0028-3878
    DOI 10.1212/WNL.0000000000009278
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ui II Zs.153: Show issues Location:
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  9. Article: Navigating Sex-Specific Disease Dynamics in Incident Dementia.

    Garg, Muskan / Liu, Xingyi / Vassilaki, Maria / Petersen, Ronald C / St Sauver, Jennifer / Sohn, Sunghwan

    Proceedings. IEEE International Conference on Bioinformatics and Biomedicine

    2024  Volume 2023, Page(s) 4065–4072

    Abstract: Dementia is among the leading causes of cognitive and functional loss and disability in older adults. Past studies suggested sex differences in health conditions and progression of cognitive decline. Existing studies on the temporal trajectory of health ... ...

    Abstract Dementia is among the leading causes of cognitive and functional loss and disability in older adults. Past studies suggested sex differences in health conditions and progression of cognitive decline. Existing studies on the temporal trajectory of health conditions for patient characterization after dementia diagnosis are scarce and ambiguous. Thus, there's limited and unclear research on how health conditions change over time after a dementia diagnosis. To this end, we aim to analyze the shift in medical conditions and examine sex-specific changes in patterns of chronic health conditions after dementia diagnosis. We centered our analysis on a 15-year window around the point of dementia diagnosis, encompassing the 5 years leading up to the diagnosis and the 10 years following it. We introduce (i) MedMet, a network metric to quantify the contribution of each medical condition, and (ii) growth and decay function for temporal trajectory analysis of medical conditions. Our experiments demonstrate that certain health conditions are more prevalent among females than males. Thus, our findings underscore the pressing need to examine differences between men and women, which could be important for healthcare utilization after a dementia diagnosis.
    Language English
    Publishing date 2024-01-18
    Publishing country United States
    Document type Journal Article
    ISSN 2156-1125
    ISSN 2156-1125
    DOI 10.1109/bibm58861.2023.10385324
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: How early can we diagnose Alzheimer disease (and is it sufficient)? The 2017 Wartenberg lecture.

    Petersen, Ronald C

    Neurology

    2018  Volume 91, Issue 9, Page(s) 395–402

    Abstract: A seismic shift in our understanding of the ability to diagnose Alzheimer disease (AD) is occurring. For the last several decades, AD has been a clinical-pathologic diagnosis, and this conceptualization of the disease has served the field well. Typically, ...

    Abstract A seismic shift in our understanding of the ability to diagnose Alzheimer disease (AD) is occurring. For the last several decades, AD has been a clinical-pathologic diagnosis, and this conceptualization of the disease has served the field well. Typically, the clinician would identify a syndrome such as mild cognitive impairment or dementia, and label the condition as "probable AD" since the diagnosis of definite AD could not be made until an autopsy revealed the presence of amyloid plaques and tau-based neurofibrillary tangles. However, with the advent of biomarkers for AD including neuroimaging and CSF, the identification of AD pathology can be made in life, which greatly enhances the ability of clinicians to be precise about the underlying etiology of a clinical syndrome. Hypothetical models of the temporal relation among the pathologic elements and the clinical symptoms have been proposed and have influenced the field enormously. This has enabled clinicians to be specific about the underlying cause of a given clinical syndrome. As such, the diagnostic capability of the clinician is evolving. However, AD pathology is only a component of the puzzle describing the causes of cognitive changes in aging. Most often, there is a multitude of pathologic entities contributing to the neuropathologic explanation of cognitive changes in aging. AD changes contribute important elements to the diagnosis, but the final answer is more complex. The field of aging and dementia will have to incorporate these additional elements.
    MeSH term(s) Alzheimer Disease/cerebrospinal fluid ; Alzheimer Disease/complications ; Alzheimer Disease/diagnosis ; Alzheimer Disease/history ; Cognition Disorders/etiology ; Community Networks/standards ; Community Networks/trends ; History, 20th Century ; Humans ; Neuroimaging/methods ; Neuroimaging/standards ; Neuroimaging/trends ; Time Factors
    Language English
    Publishing date 2018-08-08
    Publishing country United States
    Document type Historical Article ; Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 207147-2
    ISSN 1526-632X ; 0028-3878
    ISSN (online) 1526-632X
    ISSN 0028-3878
    DOI 10.1212/WNL.0000000000006088
    Database MEDical Literature Analysis and Retrieval System OnLINE

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