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  1. Article ; Online: Imaging Features of Lymphoepithelial-Like Carcinoma of the Salivary Glands.

    Zhang, Meng / Ye, Jingzhi / Li, Hongyi / Huang, Peikai / Chen, Jun / Lin, Fenghuang / Xiao, Mengqiang

    Ear, nose, & throat journal

    2022  , Page(s) 1455613221116330

    Abstract: Objective: Lymphoepithelial-like carcinoma of the salivary glands (LELCSG) is a rare tumour of unknown aetiology. No studies have reported the imaging features of primary LELCSG.: Methods: The clinical information and imaging features of eight ... ...

    Abstract Objective: Lymphoepithelial-like carcinoma of the salivary glands (LELCSG) is a rare tumour of unknown aetiology. No studies have reported the imaging features of primary LELCSG.
    Methods: The clinical information and imaging features of eight patients with LELCSG were reviewed. Computed tomography (n = 4 patients) and magnetic resonance imaging (n = 4 patients) features were analysed by two radiologists to identify the location, number, size, shape, boundary, signal intensity and enhancement of LELCSG.
    Results: The study included four women and four men, and the mean size of the tumours was 32.88 ± 3.41 mm (range, 27-38 mm). The tumours affected the parotid gland in six cases and the submandibular gland in two cases. The eight cases were evaluated by
    Conclusions: LELCSG is a lobulated, multi-nodular tumour, with some fused nodules. LELCSG lesions showed isointensity or slight hyperintensity on T1WI MRI, slight hyperintensity on T2WI MRI and
    Language English
    Publishing date 2022-07-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 750153-5
    ISSN 1942-7522 ; 0145-5613
    ISSN (online) 1942-7522
    ISSN 0145-5613
    DOI 10.1177/01455613221116330
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Diagnosis and surgical treatment of tumor-induced osteomalacia—a literature review and a case report

    Peikai Huang / Mengqiang Xiao / Meng Zhang / Jun Chen / Jingzhi Ye / Meiyi Zhao / Jiahui Tang

    The Egyptian Journal of Internal Medicine, Vol 34, Iss 1, Pp 1-

    2022  Volume 7

    Abstract: Abstract Background Tumor-induced osteomalacia (TIO) is a rare condition with fewer than 500 cases reported in the literature although described. Phosphaturic mesenchymal tumor (PMT) is often unrecognized cause of hypophosphatemia. This case report aims ... ...

    Abstract Abstract Background Tumor-induced osteomalacia (TIO) is a rare condition with fewer than 500 cases reported in the literature although described. Phosphaturic mesenchymal tumor (PMT) is often unrecognized cause of hypophosphatemia. This case report aims to highlight such a rare association which warrants clinical and radiologist attention. Case A 51-year-old man had pain in his feet 2 years prior to the most recent presentation in our clinic. The patient experienced increasingly severe body aches and pain, which affected the feet, hips, knees, ribs, waist, and shoulders. MRI and CT led to the diagnosis of multiple insufficiency fractures. Laboratory tests showed that inorganic phosphate (IP) levels had decreased to 0.52 mmol/L(0.81–1.45 mmol/L), while alkaline phosphatase (ALP) had increased to 216 U/L(38.0–126.0 U/L). Positron emission tomography computed tomography showed tumor-derived hypophosphate osteomalacia of the right iliac wing; surgical resection was performed. markers of bone metabolism and bone density returned normal postoperative, after 9 months follow-up. Conclusion The possibility of tumor-induced osteomalacia should be considered if unexplained joint pain, decreased bone mineral density, increased ALP and insufficiency fractures, and no similar family history are found in adult patients. Surgical resection of the tumor is the key to the treatment.
    Keywords Phosphaturic mesenchymal tumors ; Tumor-induced osteomalacia ; Internal medicine ; RC31-1245
    Subject code 616
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher SpringerOpen
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Corrigendum to "Hydrogen gas inhalation enhances alveolar macrophage phagocytosis in an ovalbumin-induced asthma model" [Int. Immunopharmacol. 74 (2019) 105646].

    Huang, Peikai / Wei, Shushan / Huang, Weihua / Wu, Penghui / Chen, Shuyu / Tao, Ailin / Wang, Hongyu / Liang, Zhenyu / Chen, Rongchang / Yan, Jie / Zhang, Qingling

    International immunopharmacology

    2022  Volume 112, Page(s) 109124

    Language English
    Publishing date 2022-09-06
    Publishing country Netherlands
    Document type Published Erratum
    ZDB-ID 2043785-7
    ISSN 1878-1705 ; 1567-5769
    ISSN (online) 1878-1705
    ISSN 1567-5769
    DOI 10.1016/j.intimp.2022.109124
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  4. Article ; Online: Spectrum of Chest CT Findings in a Familial Cluster of COVID-19 Infection.

    Liu, Tianzhu / Huang, Peikai / Liu, Hailong / Huang, Lesheng / Lei, Ming / Xu, Wangdong / Hu, Xiaolu / Chen, Jun / Liu, Bo

    Radiology. Cardiothoracic imaging

    2020  Volume 2, Issue 1, Page(s) e200025

    Language English
    Publishing date 2020-02-13
    Publishing country United States
    Document type Journal Article
    ISSN 2638-6135
    ISSN (online) 2638-6135
    DOI 10.1148/ryct.2020200025
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  5. Article ; Online: Use of Chest CT in Combination with Negative RT-PCR Assay for the 2019 Novel Coronavirus but High Clinical Suspicion.

    Huang, Peikai / Liu, Tianzhu / Huang, Lesheng / Liu, Hailong / Lei, Ming / Xu, Wangdong / Hu, Xiaolu / Chen, Jun / Liu, Bo

    Radiology

    2020  Volume 295, Issue 1, Page(s) 22–23

    MeSH term(s) Adult ; Betacoronavirus/isolation & purification ; COVID-19 ; Coronavirus Infections/diagnosis ; Coronavirus Infections/diagnostic imaging ; Disease Progression ; False Negative Reactions ; Humans ; Male ; Pandemics ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/diagnostic imaging ; Radiography, Thoracic/methods ; Real-Time Polymerase Chain Reaction ; SARS-CoV-2 ; Sputum/virology ; Tomography, X-Ray Computed
    Keywords covid19
    Language English
    Publishing date 2020-02-12
    Publishing country United States
    Document type Case Reports ; Journal Article ; Video-Audio Media
    ZDB-ID 80324-8
    ISSN 1527-1315 ; 0033-8419
    ISSN (online) 1527-1315
    ISSN 0033-8419
    DOI 10.1148/radiol.2020200330
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  6. Article: Altered gut microbiome compositions are associated with the severity of asthma.

    Wang, Zhiqiang / Lai, Zhengdao / Zhang, Xiaoxian / Huang, Peikai / Xie, Jiaxing / Jiang, Qian / Zhang, Qingling / Chung, Kian Fan

    Journal of thoracic disease

    2021  Volume 13, Issue 7, Page(s) 4322–4338

    Abstract: Background: Despite substantial evidence on the contribution of the diversity of the gut microbiome to the pathogenesis of asthma and allergic diseases, little is known about their relationship with asthma severity and/or clinical phenotypes. We ... ...

    Abstract Background: Despite substantial evidence on the contribution of the diversity of the gut microbiome to the pathogenesis of asthma and allergic diseases, little is known about their relationship with asthma severity and/or clinical phenotypes. We analyzed the difference in composition of the gut microbiome between subjects with asthma and healthy subjects and explored its role in the development of asthma.
    Methods: Fecal samples from 15 subjects with severe asthma (SA), 14 with non-severe asthma (NSA), and 15 healthy subjects were assessed by 16S ribosomal RNA gene sequencing methods to identify the gut bacterial composition.
    Results: Compared with those in the NSA group, patients in the SA group had a higher dose of inhaled corticosteroids, and there were more atopic subjects (60%
    Conclusions: Our findings suggest that altered gut microbiome compositions are involved in the severity of asthma and that there are specific bacteria related to different asthma phenotypes in terms of serum IgE levels.
    Language English
    Publishing date 2021-06-14
    Publishing country China
    Document type Journal Article
    ZDB-ID 2573571-8
    ISSN 2077-6624 ; 2072-1439
    ISSN (online) 2077-6624
    ISSN 2072-1439
    DOI 10.21037/jtd-20-2189
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  7. Article: Use of Chest CT in Combination with Negative RT-PCR Assay for the 2019 Novel Coronavirus but High Clinical Suspicion

    Huang, Peikai / Liu, Tianzhu / Huang, Lesheng / Liu, Hailong / Lei, Ming / Xu, Wangdong / Hu, Xiaolu / Chen, Jun / Liu, Bo

    Radiology

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #32049600
    Database COVID19

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  8. Article ; Online: Spectrum of Chest CT Findings in a Familial Cluster of COVID-19 Infection

    Liu, Tianzhu / Huang, Peikai / Liu, Hailong / Huang, Lesheng / Lei, Ming / Xu, Wangdong / Hu, Xiaolu / Chen, Jun / Liu, Bo

    Radiol Cardiothorac Imaging

    Keywords covid19
    Publisher PMC
    Document type Article ; Online
    DOI 10.1148/ryct.2020200025
    Database COVID19

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  9. Article ; Online: Corrigendum to "Transient Receptor Potential Ion Channels Mediate Adherens Junctions Dysfunction in a Toluene Diisocyanate-Induced Murine Asthma Model".

    Yao, Lihong / Chen, Shuyu / Tang, Haixiong / Huang, Peikai / Wei, Shushan / Liang, Zhenyu / Chen, Xin / Yang, Hongyu / Tao, Ailin / Chen, Rongchang / Zhang, Qingling

    Toxicological sciences : an official journal of the Society of Toxicology

    2019  Volume 170, Issue 1, Page(s) 247

    Language English
    Publishing date 2019-03-14
    Publishing country United States
    Document type Journal Article ; Published Erratum
    ZDB-ID 1420885-4
    ISSN 1096-0929 ; 1096-6080
    ISSN (online) 1096-0929
    ISSN 1096-6080
    DOI 10.1093/toxsci/kfz063
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    Zs.A 1709: Show issues Location:
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  10. Article ; Online: IL-17F, rather than IL-17A, underlies airway inflammation in a steroid-insensitive toluene diisocyanate-induced asthma model.

    Chen, Rongchang / Zhang, Qingling / Chen, Shuyu / Tang, Haixiong / Huang, Peikai / Wei, Shushan / Liang, Zhenyu / Chen, Xin / Tao, Ailin / Yao, Lihong

    The European respiratory journal

    2019  Volume 53, Issue 4

    Abstract: Steroid insensitivity constitutes a major problem for asthma management. Toluene diisocyanate (TDI) is one of the leading allergens of asthma that induces both T-helper Th2 and Th17 responses, and is often associated with poor responsiveness to steroid ... ...

    Abstract Steroid insensitivity constitutes a major problem for asthma management. Toluene diisocyanate (TDI) is one of the leading allergens of asthma that induces both T-helper Th2 and Th17 responses, and is often associated with poor responsiveness to steroid treatment in the clinic.We sought to evaluate the effects of inhaled and systemic steroids on a TDI-induced asthma model and to find how interleukin (IL)-17A and IL-17F function in this model. BALB/c mice were exposed to TDI for generating an asthma model and were treated with inhaled fluticasone propionate, systemic prednisone, anti-IL-17A, anti-IL-17F, recombinant IL-17A or IL-17F.Both fluticasone propionate and prednisone showed no effects on TDI-induced airway hyperresponsiveness (AHR), bronchial neutrophilia and eosinophilia, and epithelial goblet cell metaplasia. TDI-induced Th2 and Th17 signatures were not suppressed by fluticasone propionate or prednisone. Treatment with anti-IL-17A after TDI exposure led to increased AHR, aggravated mucus production and airway eosinophil recruitment, accompanied by amplified Th2 responses, whereas anti-IL-17F ameliorated TDI-induced AHR and airway neutrophilia, with decreased Th17 responses. Recombinant IL-17A and IL-17F showed opposite effects to the monoclonal antibodies.IL-17A and IL-17F exert distinct biological effects during airway inflammation of a TDI-induced asthma model, which is unresponsive to both inhaled and systemic steroids.
    MeSH term(s) Animals ; Asthma/drug therapy ; Asthma/immunology ; Bronchodilator Agents/therapeutic use ; Disease Models, Animal ; Drug Resistance ; Fluticasone/therapeutic use ; Glucocorticoids/therapeutic use ; Interleukin-17/physiology ; Mice ; Mice, Inbred BALB C ; Prednisone/therapeutic use ; Toluene 2,4-Diisocyanate/administration & dosage
    Chemical Substances Bronchodilator Agents ; Glucocorticoids ; Il17a protein, mouse ; Il17f protein, mouse ; Interleukin-17 ; Toluene 2,4-Diisocyanate (17X7AFZ1GH) ; Fluticasone (CUT2W21N7U) ; Prednisone (VB0R961HZT)
    Language English
    Publishing date 2019-04-04
    Publishing country England
    Document type Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 639359-7
    ISSN 1399-3003 ; 0903-1936
    ISSN (online) 1399-3003
    ISSN 0903-1936
    DOI 10.1183/13993003.01510-2018
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.MO 292: Show issues

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