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  1. Article ; Online: Extracorporeal membrane oxygenation in COVID-19: Supplementary considerations.

    Axiaq, Ariana / Haiduc, Ana Alina / Alom, Samiha / Melamed, Naomi / Harky, Amer

    Journal of cardiac surgery

    2020  Volume 35, Issue 12, Page(s) 3673–3674

    MeSH term(s) COVID-19 ; Extracorporeal Membrane Oxygenation ; Humans ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-09-16
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 639059-6
    ISSN 1540-8191 ; 0886-0440
    ISSN (online) 1540-8191
    ISSN 0886-0440
    DOI 10.1111/jocs.15026
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2221: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Loeys-Dietz syndrome pathology and aspects of cardiovascular management: A systematic review.

    Iqbal, Rizwan / Alom, Samiha / BinSaeid, Jalal / Harky, Amer

    Vascular

    2020  Volume 29, Issue 1, Page(s) 3–14

    Abstract: Loeys-Dietz syndrome is an autosomal dominant genetic disorder which is associated with significant and often crucial vascular manifestations. This review is aimed to examine current evidence on pathophysiology and management of Loeys-Dietz syndrome in ... ...

    Abstract Loeys-Dietz syndrome is an autosomal dominant genetic disorder which is associated with significant and often crucial vascular manifestations. This review is aimed to examine current evidence on pathophysiology and management of Loeys-Dietz syndrome in current era. A comprehensive electronic search was done to identify the articles that discussed all the aspects of Loeys-Dietz syndrome, combined key words and Medical Subject Headings (MeSH) terms were used. Relevant articles have been summarized in each relevant section. Loeys-Dietz syndrome is an autosomal dominant genetic disorder which has combined and multi-systemic manifestations. The increased breakdown of extracellular matrix predisposes an individual to developing aneurysms in the aortic tree which is undoubtedly the most significant complication of this disorder. Understanding the pathophysiology and natural history of Loeys-Dietz syndrome and regular surveillance is important to plan prophylactic interventions to prevent life-threatening aortic emergencies which can be fatal. Loeys-Dietz syndrome is an aggressive genetic condition that predisposes an individual to the development of life-threatening aortic aneurysms. Our understanding of Loeys-Dietz syndrome remains ever-changing and it is likely that the knowledge regarding its diagnosis and treatment will become more clearly defined in the coming years with deeper genetic studies.
    MeSH term(s) Adult ; Aged ; Aorta/pathology ; Aorta/surgery ; Blood Vessel Prosthesis Implantation/adverse effects ; Blood Vessel Prosthesis Implantation/mortality ; Dilatation, Pathologic ; Endovascular Procedures/adverse effects ; Endovascular Procedures/mortality ; Female ; Genetic Predisposition to Disease ; Humans ; Loeys-Dietz Syndrome/genetics ; Loeys-Dietz Syndrome/mortality ; Loeys-Dietz Syndrome/pathology ; Loeys-Dietz Syndrome/surgery ; Male ; Middle Aged ; Phenotype ; Risk Factors ; Treatment Outcome ; Vascular Remodeling
    Language English
    Publishing date 2020-06-19
    Publishing country England
    Document type Journal Article ; Systematic Review
    ZDB-ID 2137151-9
    ISSN 1708-539X ; 1708-5381
    ISSN (online) 1708-539X
    ISSN 1708-5381
    DOI 10.1177/1708538120934582
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 4277: Show issues Location:
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    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 590: Show issues

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  3. Article ; Online: Role of extracorporeal membrane oxygenation in COVID-19: A systematic review.

    Haiduc, Ana Alina / Alom, Samiha / Melamed, Naomi / Harky, Amer

    Journal of cardiac surgery

    2020  Volume 35, Issue 10, Page(s) 2679–2687

    Abstract: Objective: We aimed to examine the literature evidence behind using extracorporeal membrane oxygenation in COVID-19 patients in a systematic review manner.: Methods: We conducted a systematic review using Preferred Reporting Items for Systematic ... ...

    Abstract Objective: We aimed to examine the literature evidence behind using extracorporeal membrane oxygenation in COVID-19 patients in a systematic review manner.
    Methods: We conducted a systematic review using Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA) guidelines. A comprehensive literature search was conducted on Global Health Medline, EMBASE, and Cochrane databases using keywords and MeSH terms to identify articles pertaining to extracorporeal membrane oxygenation (ECMO) and Coronavirus disease 2019 (COVID-19). A narrative synthesis was then undertaken to identify the key themes.
    Results: A total of 25 articles met the inclusion criteria of this systematic review. Three main themes were identified following the data extraction: (a) evidence against/inconclusive regarding ECMO for COVID-19, (b) evidence supporting ECMO for COVID-19, and finally (c) VV-ECMO and VA-ECMO. After combining the data, there were 3428 patients diagnosed with COVID-19 and 95 ECMO-associated deaths (19.83%).
    Conclusion: Our study highlights the paucity of evidence and the need for further data to consolidate the efficacy of ECMO in improving patient outcomes. Although ECMO has been shown to be beneficial in a selected group of patients, the recuperative effects of ECMO remain inconclusive. We must ensure that risk-benefit analysis for each candidate is conducted thoroughly so that patients that have increased probability of survival can benefit from this scarce resource.
    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections/epidemiology ; Coronavirus Infections/therapy ; Extracorporeal Membrane Oxygenation/methods ; Humans ; Pandemics ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/therapy ; SARS-CoV-2 ; Treatment Outcome
    Keywords covid19
    Language English
    Publishing date 2020-07-27
    Publishing country United States
    Document type Journal Article ; Systematic Review
    ZDB-ID 639059-6
    ISSN 1540-8191 ; 0886-0440
    ISSN (online) 1540-8191
    ISSN 0886-0440
    DOI 10.1111/jocs.14879
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2221: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: The effect of antivirals on COVID-19: a systematic review.

    Hussain, Nafisa / Yoganathan, Anusha / Hewage, Savini / Alom, Samiha / Harky, Amer

    Expert review of anti-infective therapy

    2020  Volume 19, Issue 4, Page(s) 473–486

    Abstract: Introduction: Coronavirus Disease 2019 is a contagious infection that has infected millions worldwide. The objective of this systematic review is to identify studies pertaining to antivirals, both as sole and combined therapies, in COVID-19 patients and ...

    Abstract Introduction: Coronavirus Disease 2019 is a contagious infection that has infected millions worldwide. The objective of this systematic review is to identify studies pertaining to antivirals, both as sole and combined therapies, in COVID-19 patients and review the clinical outcomes of these treatment methods.
    Areas covered: A systematic review was conducted using Preferred Reporting Items or Systematic Reviews and Meta-analysis (PRISMA) guidelines. A literature search was done on Medline, Global Health, and EMBASE using keywords and MeSH terms relevant to COVID- 19 and antivirals. Limits were put on date to obtain articles between December 2019 to May 2020 (the time at which the search was performed). 776 articles were identified and screened. After screening, 16 studies were included. The narrative synthesis revealed three key themes (1) Use of antivirals only (such as lopinavir, umifenovir, and remdesivir), (2) Use of lopinavir-ritonavir alongside other treatments, and (3) Use of other antivirals in combination with other treatments.
    Expert opinion: Using antivirals in combination with other treatments has potential; however, further randomized controlled trials with larger sample sizes are required to identify the best candidate components that should comprise combined treatments for COVID-19. This should optimize treatment efficacy and improve patient outcomes.
    MeSH term(s) Adenosine Monophosphate/administration & dosage ; Adenosine Monophosphate/analogs & derivatives ; Alanine/administration & dosage ; Alanine/analogs & derivatives ; Antiviral Agents/administration & dosage ; COVID-19/diagnosis ; COVID-19/drug therapy ; COVID-19/epidemiology ; Clinical Trials as Topic/methods ; Drug Therapy, Combination ; Humans ; Ritonavir/administration & dosage ; Treatment Outcome
    Chemical Substances Antiviral Agents ; remdesivir (3QKI37EEHE) ; Adenosine Monophosphate (415SHH325A) ; Ritonavir (O3J8G9O825) ; Alanine (OF5P57N2ZX)
    Keywords covid19
    Language English
    Publishing date 2020-10-20
    Publishing country England
    Document type Journal Article ; Systematic Review
    ZDB-ID 2181279-2
    ISSN 1744-8336 ; 1478-7210
    ISSN (online) 1744-8336
    ISSN 1478-7210
    DOI 10.1080/14787210.2021.1823832
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6106: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  5. Article ; Online: Use of ECMO in Patients With Coronavirus Disease 2019: Does the Evidence Suffice?

    Alom, Samiha / Haiduc, Ana Alina / Melamed, Naomi / Axiaq, Ariana / Harky, Amer

    Journal of cardiothoracic and vascular anesthesia

    2020  Volume 35, Issue 4, Page(s) 1256–1262

    MeSH term(s) COVID-19/diagnosis ; COVID-19/therapy ; Extracorporeal Membrane Oxygenation/adverse effects ; Extracorporeal Membrane Oxygenation/methods ; Humans ; Respiratory Distress Syndrome/therapy ; SARS-CoV-2 ; Treatment Outcome
    Keywords covid19
    Language English
    Publishing date 2020-07-30
    Publishing country United States
    Document type Letter
    ZDB-ID 1067317-9
    ISSN 1532-8422 ; 1053-0770
    ISSN (online) 1532-8422
    ISSN 1053-0770
    DOI 10.1053/j.jvca.2020.07.070
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2203: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 31: Show issues

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  6. Article ; Online: Role of extracorporeal membrane oxygenation in COVID‐19

    Haiduc, Ana Alina / Alom, Samiha / Melamed, Naomi / Harky, Amer

    Journal of Cardiac Surgery

    A systematic review

    2020  Volume 35, Issue 10, Page(s) 2679–2687

    Keywords Surgery ; Cardiology and Cardiovascular Medicine ; covid19
    Language English
    Publisher Wiley
    Publishing country us
    Document type Article ; Online
    ZDB-ID 639059-6
    ISSN 1540-8191 ; 0886-0440
    ISSN (online) 1540-8191
    ISSN 0886-0440
    DOI 10.1111/jocs.14879
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2221: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: The effect of antivirals on COVID-19

    Hussain, Nafisa / Yoganathan, Anusha / Hewage, Savini / Alom, Samiha / Harky, Amer

    Expert Review of Anti-infective Therapy

    a systematic review

    2020  , Page(s) 1–14

    Keywords Microbiology (medical) ; Microbiology ; Virology ; Infectious Diseases ; covid19
    Language English
    Publisher Informa UK Limited
    Publishing country uk
    Document type Article ; Online
    ZDB-ID 2181279-2
    ISSN 1744-8336 ; 1478-7210
    ISSN (online) 1744-8336
    ISSN 1478-7210
    DOI 10.1080/14787210.2021.1823832
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6106: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  8. Article ; Online: Harvesting internal mammary artery: a narrative review.

    Alom, Samiha / Yang, Nayoung / Bin Saeid, Jalal / Zeinah, Mohamed / Harky, Amer

    The Journal of cardiovascular surgery

    2020  Volume 61, Issue 6, Page(s) 790–801

    Abstract: Introduction: Scientific literature has highlighted the development of surgical procedures with studies investigating optimal selection of arterial conduit, ideal harvesting method and type of graft. There have also been studies on the utility and ... ...

    Abstract Introduction: Scientific literature has highlighted the development of surgical procedures with studies investigating optimal selection of arterial conduit, ideal harvesting method and type of graft. There have also been studies on the utility and efficiency of harvesting the internal mammary artery (IMA) through minimally invasive techniques such as endoscopic and robotic assisted methods. In the pursuit of a more total and complete revascularization of the coronary arteries, surgeons have also explored more extensive anastomosis techniques, i.e. sequential and no-touch. This review analyzes the literature in order to better understand the various methods for harvesting and using the IMA in coronary artery bypass graft (CABG) through outlining the pros and cons of each methodology.
    Evidence acquisition: Literature search on PubMed and Google Scholar was performed using search terms such as "CABG," "IMA," "internal thoracic artery," "harvesting," "technique," and "approach." Manuscripts in languages other than English were not considered. Manuscripts that assess outcomes of IMA harvesting are reviewed and included.
    Evidence synthesis: A review of 48 studies, narrowed down from 150 articles that were retrieved, were used to evaluate current evidence for different IMA harvesting techniques. This includes evidence comparing various techniques: skeletonized and pedicled harvesting, minimally invasive techniques for harvesting; free arterial and in-situ grafts; no-aortic touch technique sequential grafting.
    Conclusions: Each technique and harvesting method is associate with various advantages and disadvantages. Common patterns in patient outcomes were identified for many of the techniques. This review provides a summary and overview of the current evidence base for CAGB surgery and identifies gaps in the evidence base to direct future research.
    MeSH term(s) Animals ; Coronary Artery Bypass/adverse effects ; Coronary Artery Disease/surgery ; Humans ; Mammary Arteries/transplantation ; Tissue and Organ Harvesting/adverse effects ; Treatment Outcome
    Language English
    Publishing date 2020-09-04
    Publishing country Italy
    Document type Journal Article ; Review
    ZDB-ID 80143-4
    ISSN 1827-191X ; 0021-9509
    ISSN (online) 1827-191X
    ISSN 0021-9509
    DOI 10.23736/S0021-9509.20.11216-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 469: Show issues Location:
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  9. Article: Use of ECMO in Patients With Coronavirus Disease 2019: Does the Evidence Suffice?

    Alom, Samiha / Haiduc, Ana Alina / Melamed, Naomi / Axiaq, Ariana / Harky, Amer

    J. cardiothoracic vasc. anest

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #745887
    Database COVID19

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  10. Article: Extracorporeal membrane oxygenation in COVID-19: Supplementary considerations

    Axiaq, Ariana / Haiduc, Ana Alina / Alom, Samiha / Melamed, Naomi / Harky, Amer

    J. card. surg

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #772406
    Database COVID19

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