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  1. Book ; Online: Civic Medicine

    Mendelsohn, J. Andrew / Kinzelbach, Annemarie / Schilling, Ruth

    Physician, Polity, and Pen in Early Modern Europe

    (Routledge / Asian Studies Association of Australia (ASAA) South Asian Series)

    2020  

    Series title Routledge / Asian Studies Association of Australia (ASAA) South Asian Series
    Keywords Humanities ; European history ; civic doctors ; Early modern European medicine ; transformative itineraries ; urban polity
    Language English
    Size 1 electronic resource (332 pages)
    Publisher Taylor and Francis
    Document type Book ; Online
    Note English
    HBZ-ID HT030610657
    ISBN 9781032090580 ; 1032090588
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book ; Online ; E-Book: Civic medicine

    Mendelsohn, John Andrew / Kinzelbach, Annemarie / Schilling, Ruth

    physician, polity, and pen in early modern Europe

    (History of medicine in context series)

    2020  

    Author's details edited by J. Andrew Mendelsohn, Annemarie Kinzelbach, and Ruth Schilling
    Series title History of medicine in context series
    Keywords Public health / Europe / History ; Social medicine / Europe / History ; Medicine / History ; HISTORY ; Renaissance ; HISTORY ; General
    Language English
    Size 1 Online-Ressource (xiv, 316 Seiten), Illustrationen
    Publisher Routledge, Taylor & Francis Group
    Publishing place London
    Publishing country Great Britain
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT020258714
    ISBN 978-1-317-02140-7 ; 978-1-315-55469-3 ; 9781472453587 ; 1-317-02140-1 ; 1-315-55469-0 ; 1472453581
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Book ; Online ; E-Book: Precision Medicine

    McCarthy, Jeanette J. / Mendelsohn, Bryce A.

    A Guide to Genomics in Clinical Practice

    2017  

    Abstract: A complete how-to-guide for incorporating precision medicine into any type of practice. ...

    Author's details Jeanette J. McCarthy, Bryce A. Mendelsohn
    Abstract A complete how-to-guide for incorporating precision medicine into any type of practice.
    MeSH term(s) Genetic Testing ; Genetic Predisposition to Disease ; Precision Medicine ; Genetics, Medical/ethics
    Subject code 616/.042
    Language English
    Size 1 online resource :, illustrations
    Edition 1st ed.
    Publisher McGraw-Hill Education LLC
    Publishing place New York, N.Y
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 978-1-259-64413-9 ; 1-259-64413-8
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  4. Article: In memoriam: Alma J. Green.

    Mendelsohn, L M

    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde

    1976  Volume 50, Issue 41, Page(s) 1631

    MeSH term(s) Family Practice/history ; History of Medicine ; South Africa
    Language English
    Publishing date 1976-09-25
    Publishing country South Africa
    Document type Biography ; Historical Article ; Journal Article
    ZDB-ID 390968-2
    ISSN 2078-5135 ; 0256-9574 ; 0038-2469
    ISSN (online) 2078-5135
    ISSN 0256-9574 ; 0038-2469
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ua VI Zs.406: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 645: Show issues

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  5. Article: RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement.

    Shinkai, Y / Rathbun, G / Lam, K P / Oltz, E M / Stewart, V / Mendelsohn, M / Charron, J / Datta, M / Young, F / Stall, A M

    Cell

    1992  Volume 68, Issue 5, Page(s) 855–867

    Abstract: ... did not rearrange their immunoglobulin or T cell receptor loci. Lack of V(D)J recombination activity ... Therefore, loss of RAG-2 function in vivo results in total inability to initiate V(D)J rearrangement, leading ... abnormality detected in RAG-2 mutant mice, RAG-2 function and V(D)J recombinase activity, per se, are not ...

    Abstract We have generated mice that carry a germline mutation in which a large portion of the RAG-2 coding region is deleted. Homozygous mutants are viable but fail to produce mature B or T lymphocytes. Very immature lymphoid cells were present in primary lymphoid organs of mutant animals as defined by surface marker analyses and Abelson murine leukemia virus (A-MuLV) transformation assays. However, these cells did not rearrange their immunoglobulin or T cell receptor loci. Lack of V(D)J recombination activity in mutant pre-B cell lines could be restored by introduction of a functional RAG-2 expression vector. Therefore, loss of RAG-2 function in vivo results in total inability to initiate V(D)J rearrangement, leading to a novel severe combined immune deficient (SCID) phenotype. Because the SCID phenotype was the only obvious abnormality detected in RAG-2 mutant mice, RAG-2 function and V(D)J recombinase activity, per se, are not required for development of cells other than lymphocytes.
    MeSH term(s) Animals ; Antibodies, Monoclonal ; B-Lymphocytes/chemistry ; Base Sequence ; DNA Nucleotidyltransferases/analysis ; DNA-Binding Proteins ; Gene Rearrangement, T-Lymphocyte/genetics ; Integrases ; Mice ; Mice, Mutant Strains ; Mice, Transgenic ; Molecular Sequence Data ; Phenotype ; Proteins/analysis ; Proteins/genetics ; Recombinases ; T-Lymphocytes/chemistry
    Chemical Substances Antibodies, Monoclonal ; DNA-Binding Proteins ; Proteins ; Rag2 protein, mouse ; Recombinases ; V(D)J recombination activating protein 2 ; DNA Nucleotidyltransferases (EC 2.7.7.-) ; Integrases (EC 2.7.7.-) ; integron integrase IntI1 (EC 2.7.7.-)
    Language English
    Publishing date 1992-03-06
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, P.H.S.
    ZDB-ID 187009-9
    ISSN 1097-4172 ; 0092-8674
    ISSN (online) 1097-4172
    ISSN 0092-8674
    DOI 10.1016/0092-8674(92)90029-c
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1167: Show issues Location:
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    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MG 58: Show issues

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  6. Article ; Online: Exposure to Sublethal Concentrations of Lead (Pb) Affects Ecologically Relevant Behaviors in House Sparrows (Passer domesticus).

    Di Liberto, Joseph F / Griffith, Simon C / Hall, Cara J / Mendelsohn, Alexandra S / Swaddle, John P

    Archives of environmental contamination and toxicology

    2024  Volume 86, Issue 3, Page(s) 199–216

    Abstract: Global contamination of environments with lead (Pb) poses threats to many ecosystems and populations. While exposure to Pb is toxic at high concentrations, recent literature has shown that lower concentrations can also cause sublethal, deleterious ... ...

    Abstract Global contamination of environments with lead (Pb) poses threats to many ecosystems and populations. While exposure to Pb is toxic at high concentrations, recent literature has shown that lower concentrations can also cause sublethal, deleterious effects. However, there remains relatively little causal investigation of how exposure to lower concentrations of environmental Pb affects ecologically important behaviors. Behaviors often represent first-line responses of an organism and its internal physiological, molecular, and genetic responses to a changing environment. Hence, better understanding how behaviors are influenced by pollutants such as Pb generates crucial information on how species are coping with the effects of pollution more broadly. To better understand the effects of sublethal Pb on behavior, we chronically exposed adult wild-caught, captive house sparrows (Passer domesticus) to Pb-exposed drinking water and quantified a suite of behavioral outcomes: takeoff flight performance, activity in a novel environment, and in-hand struggling and breathing rate while being handled by an experimenter. Compared to controls (un-exposed drinking water), sparrows exposed to environmentally relevant concentrations of Pb exhibited decreases in takeoff flight performance and reduced movements in a novel environment following 9-10 weeks of exposure. We interpret this suite of results to be consistent with Pb influencing fundamental neuro-muscular abilities, making it more difficult for exposed birds to mount faster movements and activities. It is likely that suppression of takeoff flight and reduced movements would increase the predation risk of similar birds in the wild; hence, we also conclude that the effects we observed could influence fitness outcomes for individuals and populations altering ecological interactions within more naturalistic settings.
    MeSH term(s) Humans ; Animals ; Sparrows/genetics ; Lead/toxicity ; Ecosystem ; Drinking Water
    Chemical Substances Lead (2P299V784P) ; Drinking Water
    Language English
    Publishing date 2024-04-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 185986-9
    ISSN 1432-0703 ; 0090-4341
    ISSN (online) 1432-0703
    ISSN 0090-4341
    DOI 10.1007/s00244-024-01062-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1182: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  7. Article ; Online: What Role Do the Impacts from High Emissions and High Temperatures Have on Choosing Optimal Mitigation Targets?

    Yoo, Jonghyun / Mendelsohn, Robert

    Environmental science & technology

    2021  Volume 55, Issue 22, Page(s) 15025–15030

    Abstract: When choosing among emission trajectories that lead to final expected temperatures between 2 and 4 °C, society needs to weigh the extra mitigation cost of each strategy against the extra benefit (additional reduced damage). The damage associated with ... ...

    Abstract When choosing among emission trajectories that lead to final expected temperatures between 2 and 4 °C, society needs to weigh the extra mitigation cost of each strategy against the extra benefit (additional reduced damage). The damage associated with high emissions that lead to high temperatures play no role in this calculation. With uncertainty about the link between emissions and temperature, high temperatures can play a role in desired near term mitigation but it will generally be a modest effect. We need to focus scientific attention on policy relevant emission paths and their consequences and pay much less attention to what happens in high emission scenarios.
    MeSH term(s) Climate Change ; Temperature ; Uncertainty
    Language English
    Publishing date 2021-10-25
    Publishing country United States
    Document type Journal Article
    ISSN 1520-5851
    ISSN (online) 1520-5851
    DOI 10.1021/acs.est.1c04202
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Commentary on "Recombinant Humanized Anti-HER2 Antibody (Herceptin) Enhances the Antitumor Activity of Paclitaxel and Doxorubicin against HER2/neu Overexpressing Human Breast Cancer Xenografts" (A Follow Up).

    Mendelsohn, John

    Cancer research

    2016  Volume 76, Issue 18, Page(s) 5192–5194

    MeSH term(s) Animals ; Antineoplastic Combined Chemotherapy Protocols/history ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Breast Neoplasms/drug therapy ; Breast Neoplasms/enzymology ; Breast Neoplasms/history ; Breast Neoplasms/pathology ; Clinical Trials as Topic/history ; Doxorubicin/administration & dosage ; Female ; History, 20th Century ; Humans ; Mice ; Paclitaxel/administration & dosage ; Receptor, ErbB-2/biosynthesis ; Trastuzumab/administration & dosage ; Xenograft Model Antitumor Assays
    Chemical Substances Doxorubicin (80168379AG) ; ERBB2 protein, human (EC 2.7.10.1) ; Receptor, ErbB-2 (EC 2.7.10.1) ; Trastuzumab (P188ANX8CK) ; Paclitaxel (P88XT4IS4D)
    Language English
    Publishing date 2016--15
    Publishing country United States
    Document type Historical Article ; Journal Article
    ZDB-ID 1432-1
    ISSN 1538-7445 ; 0008-5472
    ISSN (online) 1538-7445
    ISSN 0008-5472
    DOI 10.1158/0008-5472.CAN-16-2269
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Uh III Zs.135/5: Show issues Location:
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  9. Article ; Online: Headway made towards biosignatures for incipient tuberculosis.

    Scriba, Thomas J / Mendelsohn, Simon C

    The Lancet. Respiratory medicine

    2020  Volume 8, Issue 4, Page(s) 328–330

    MeSH term(s) Automobile Driving ; Humans ; Tuberculosis
    Language English
    Publishing date 2020-01-17
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Comment
    ZDB-ID 2686754-0
    ISSN 2213-2619 ; 2213-2600
    ISSN (online) 2213-2619
    ISSN 2213-2600
    DOI 10.1016/S2213-2600(19)30355-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 7041: Show issues Location:
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  10. Book ; Online: Bridging Nations

    Mendelsohn, Julia / Ghosh, Sayan / Jurgens, David / Budak, Ceren

    Quantifying the Role of Multilinguals in Communication on Social Media

    2023  

    Abstract: Social media enables the rapid spread of many kinds of information, from memes to social movements. However, little is known about how information crosses linguistic boundaries. We apply causal inference techniques on the European Twitter network to ... ...

    Abstract Social media enables the rapid spread of many kinds of information, from memes to social movements. However, little is known about how information crosses linguistic boundaries. We apply causal inference techniques on the European Twitter network to quantify multilingual users' structural role and communication influence in cross-lingual information exchange. Overall, multilinguals play an essential role; posting in multiple languages increases betweenness centrality by 13%, and having a multilingual network neighbor increases monolinguals' odds of sharing domains and hashtags from another language 16-fold and 4-fold, respectively. We further show that multilinguals have a greater impact on diffusing information less accessible to their monolingual compatriots, such as information from far-away countries and content about regional politics, nascent social movements, and job opportunities. By highlighting information exchange across borders, this work sheds light on a crucial component of how information and ideas spread around the world.

    Comment: ICWSM 2023 (please cite accordingly); see https://github.com/juliamendelsohn/bridging-nations for data, models, and code
    Keywords Computer Science - Social and Information Networks ; Computer Science - Computation and Language
    Subject code 306
    Publishing date 2023-04-07
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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