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  1. Book ; Thesis: Osseointegration von Kurzimplantaten nach Verwendung eines Kollagen-Kegels mit integrierter Membran im posterioren maxillären Schweinekiefer

    Schuster, Stefan

    eine Pilotstudie

    2017  

    Author's details von Stefan Schuster
    Language German
    Size V, 77 Blätter, Illustrationen
    Publishing place Dresden
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Technische Universität Dresden, 2017
    HBZ-ID HT019682550
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2018 E 462 order for loan Magazin

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  2. Article ; Online: Reinhart Heinrich: In memoriam of an exceptional scholar.

    Schuster, Stefan

    Bio Systems

    2023  Volume 231, Page(s) 104965

    Abstract: In the Mathematical Biology community, Reinhart Heinrich (1946-2006) is well-known as one of the founders of Metabolic Control Analysis. Moreover, he made significant contributions to the modelling of erythrocyte metabolism and signal transduction ... ...

    Abstract In the Mathematical Biology community, Reinhart Heinrich (1946-2006) is well-known as one of the founders of Metabolic Control Analysis. Moreover, he made significant contributions to the modelling of erythrocyte metabolism and signal transduction cascades, optimality principles in metabolism, theoretical membrane biophysics and other topics. Here, the historical context of his scientific work is outlined and numerous personal memories of the scholarship of, and cooperation with, Reinhart Heinrich are narrated. Attention is drawn again to the pros and cons of normalized and non-normalized control coefficients. The role of the Golden Ratio in a dynamic optimization problem in genetic regulation of metabolism is discussed. Overall, this article is aimed at keeping alive the memory of a unique university teacher, researcher and friend.
    Language English
    Publishing date 2023-07-07
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 186234-0
    ISSN 1872-8324 ; 0303-2647
    ISSN (online) 1872-8324
    ISSN 0303-2647
    DOI 10.1016/j.biosystems.2023.104965
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 768: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  3. Article ; Online: The archerfish predictive C-start.

    Schuster, Stefan

    Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology

    2023  Volume 209, Issue 5, Page(s) 827–837

    Abstract: A very quick decision enables hunting archerfish to secure downed prey even when they are heavily outnumbered by competing other surface-feeding fish. Based exclusively on information that is taken briefly after the onset of prey motion, the fish select ... ...

    Abstract A very quick decision enables hunting archerfish to secure downed prey even when they are heavily outnumbered by competing other surface-feeding fish. Based exclusively on information that is taken briefly after the onset of prey motion, the fish select a rapid C-start that turns them right towards the later point of catch. Moreover, the C-start, and not later fin strokes, already lends the fish the speed needed to arrive at just the right time. The archerfish predictive C-starts are kinematically not distinguishable from escape C-starts made by the same individual and are among the fastest C-starts known in teleost fish. The start decisions allow the fish-for ballistically falling prey-to respond accurately to any combination of the initial variables of prey movement and for any position and orientation of the responding fish. The start decisions do not show a speed-accuracy tradeoff and their accuracy is buffered against substantial changes of environmental parameters. Here, I introduce key aspects of this high-speed decision that combines speed, complexity, and precision in an unusual way.
    MeSH term(s) Animals ; Predatory Behavior/physiology ; Perciformes ; Fishes ; Movement ; Motion Perception
    Language English
    Publishing date 2023-07-23
    Publishing country Germany
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 120907-3
    ISSN 1432-1351 ; 0302-9824 ; 0373-0859 ; 0340-7594
    ISSN (online) 1432-1351
    ISSN 0302-9824 ; 0373-0859 ; 0340-7594
    DOI 10.1007/s00359-023-01658-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Uc I Zs.170: Show issues Location:
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  4. Article ; Online: How Plant Toxins Cause Early Larval Mortality in Herbivorous Insects: An Explanation by Modeling the Net Energy Curve.

    Chakraborty, Suman / Schuster, Stefan

    Toxins

    2024  Volume 16, Issue 2

    Abstract: Plants store chemical defenses that act as toxins against herbivores, such as toxic isothiocyanates (ITCs) in Brassica plants, hydrolyzed from glucosinolate (GLS) precursors. The fitness of herbivorous larvae can be strongly affected by these toxins, ... ...

    Abstract Plants store chemical defenses that act as toxins against herbivores, such as toxic isothiocyanates (ITCs) in Brassica plants, hydrolyzed from glucosinolate (GLS) precursors. The fitness of herbivorous larvae can be strongly affected by these toxins, causing immature death. We modeled this phenomenon using a set of ordinary differential equations and established a direct relationship between feeding, toxin exposure, and the net energy of a larva, where the fitness of an organism is proportional to its net energy according to optimal foraging theory. Optimal foraging theory is widely used in ecology to model the feeding and searching behavior of organisms. Although feeding provides energy gain, plant toxins and foraging cause energy loss for the larvae. Our equations explain that toxin exposure and foraging can sharply reduce larval net energy to zero at an instar. Since herbivory needs energy, the only choice left for a larva is to stop feeding at that time point. If that is significantly earlier than the end of the last instar stage, the larva dies without food. Thus, we show that plant toxins can cause immature death in larvae from the perspective of optimal foraging theory.
    MeSH term(s) Animals ; Larva ; Herbivory ; Butterflies ; Insecta ; Brassica ; Plants
    Language English
    Publishing date 2024-02-01
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2518395-3
    ISSN 2072-6651 ; 2072-6651
    ISSN (online) 2072-6651
    ISSN 2072-6651
    DOI 10.3390/toxins16020072
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Book ; Thesis: Untersuchung neuartiger Behandlungskonzepte für L-Dopa induzierte Dyskinesien in der Parkinson Krankheit

    Schuster, Stefan

    2008  

    Author's details von Stefan Schuster
    Language German
    Size 124 Bl. in getr. Zählung : Ill., graph. Darst.
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Tübingen, Univ., Diss., 2008
    HBZ-ID HT015777087
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2008 D 948 order for loan Magazin

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  6. Article ; Online: Studying mixed-species biofilms of Candida albicans and Staphylococcus aureus using evolutionary game theory.

    Dühring, Sybille / Schuster, Stefan

    PloS one

    2024  Volume 19, Issue 3, Page(s) e0297307

    Abstract: Mixed-species biofilms of Candida albicans and Staphylococcus aureus pose a significant clinical challenge due to their resistance to the human immune system and antimicrobial therapy. Using evolutionary game theory and nonlinear dynamics, we analyse the ...

    Abstract Mixed-species biofilms of Candida albicans and Staphylococcus aureus pose a significant clinical challenge due to their resistance to the human immune system and antimicrobial therapy. Using evolutionary game theory and nonlinear dynamics, we analyse the complex interactions between these organisms to understand their coexistence in the human host. We determine the Nash equilibria and evolutionary stable strategies of the game between C. albicans and S. aureus and point out different states of the mixed-species biofilm. Using replicator equations we study the fungal-bacterial interactions on a population level. Our focus is on the influence of available nutrients and the quorum sensing molecule farnesol, including the potential therapeutic use of artificially added farnesol. We also investigate the impact of the suggested scavenging of C. albicans hyphae by S. aureus. Contrary to common assumptions, we confirm the hypothesis that under certain conditions, mixed-species biofilms are not universally beneficial. Instead, different Nash equilibria occur depending on encountered conditions (i.e. varying farnesol levels, either produced by C. albicans or artificially added), including antagonism. We further show that the suggested scavenging of C. albicans' hyphae by S. aureus does not influence the overall outcome of the game. Moreover, artificially added farnesol strongly affects the dynamics of the game, although its use as a medical adjuvant (add-on medication) may pose challenges.
    MeSH term(s) Humans ; Staphylococcus aureus ; Candida albicans ; Farnesol/pharmacology ; Game Theory ; Non-alcoholic Fatty Liver Disease ; Biofilms ; Staphylococcal Infections
    Chemical Substances Farnesol (4602-84-0)
    Language English
    Publishing date 2024-03-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0297307
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Connexins evolved after early chordates lost innexin diversity.

    Welzel, Georg / Schuster, Stefan

    eLife

    2022  Volume 11

    Abstract: Gap junction channels are formed by two unrelated protein families. Non-chordates use the primordial innexins, while chordates use connexins that superseded the gap junction function of innexins. Chordates retained innexin-homologs, but N-glycosylation ... ...

    Abstract Gap junction channels are formed by two unrelated protein families. Non-chordates use the primordial innexins, while chordates use connexins that superseded the gap junction function of innexins. Chordates retained innexin-homologs, but N-glycosylation prevents them from forming gap junctions. It is puzzling why chordates seem to exclusively use the new gap junction protein and why no chordates should exist that use non-glycosylated innexins to form gap junctions. Here, we identified glycosylation sites of 2388 innexins from 174 non-chordate and 276 chordate species. Among all chordates, we found not a single innexin without glycosylation sites. Surprisingly, the glycosylation motif is also widespread among non-chordate innexins indicating that glycosylated innexins are not a novelty of chordates. In addition, we discovered a loss of innexin diversity during early chordate evolution. Most importantly, lancelets, which lack connexins, exclusively possess only one highly conserved innexin with one glycosylation site. A bottleneck effect might thus explain why connexins have become the only protein used to form chordate gap junctions.
    MeSH term(s) Animals ; Chordata/genetics ; Connexins/genetics ; Evolution, Molecular ; Gap Junctions/genetics ; Gap Junctions/metabolism
    Chemical Substances Connexins
    Language English
    Publishing date 2022-01-19
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2687154-3
    ISSN 2050-084X ; 2050-084X
    ISSN (online) 2050-084X
    ISSN 2050-084X
    DOI 10.7554/eLife.74422
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Electric catfish hearts are not intrinsically immune to electric shocks.

    Welzel, Georg / Schuster, Stefan

    The Journal of experimental biology

    2022  Volume 225, Issue 15

    Abstract: High voltage electric shocks cause life threatening cardiac injuries such as sudden cardiac standstill or severe myocardial injury. Here, we analysed the physiology of the heart of the strongly electric catfish (Malapterurus beninensis) that stuns prey ... ...

    Abstract High voltage electric shocks cause life threatening cardiac injuries such as sudden cardiac standstill or severe myocardial injury. Here, we analysed the physiology of the heart of the strongly electric catfish (Malapterurus beninensis) that stuns prey with high-voltage shocks but is immune to its own, as well as external, high-voltage shocks. Neither a detailed analysis of the electrocardiogram nor the structure of the heart indicated a specialized cardiac conduction system. Using a suitable perfusion system, we discovered that, despite its immunity in vivo, the explanted heart of electric catfish can readily be activated by external electrical currents and is equally sensitive to electric shock-induced arrhythmias as similar-sized goldfish hearts. The surprise thus is that the electric catfish has a vulnerable heart that requires to be protected by highly efficient but presently unknown means.
    MeSH term(s) Animals ; Arrhythmias, Cardiac ; Catfishes ; Electric Countershock ; Electrocardiography ; Heart/physiology
    Language English
    Publishing date 2022-08-10
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 218085-6
    ISSN 1477-9145 ; 0022-0949
    ISSN (online) 1477-9145
    ISSN 0022-0949
    DOI 10.1242/jeb.244307
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2629: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: Hunting in archerfish - an ecological perspective on a remarkable combination of skills.

    Schuster, Stefan

    The Journal of experimental biology

    2018  Volume 221, Issue Pt 24

    Abstract: Archerfish are well known for using jets of water to dislodge distant aerial prey from twigs or leaves. This Review gives a brief overview of a number of skills that the fish need to secure prey with their shooting technique. Archerfish are opportunistic ...

    Abstract Archerfish are well known for using jets of water to dislodge distant aerial prey from twigs or leaves. This Review gives a brief overview of a number of skills that the fish need to secure prey with their shooting technique. Archerfish are opportunistic hunters and, even in the wild, shoot at artificial objects to determine whether these are rewarding. They can detect non-moving targets and use efficient search strategies with characteristics of human visual search. Their learning of how to engage targets can be remarkably efficient and can show impressive degrees of generalization, including learning from observation. In other cases, however, the fish seem unable to learn and it requires some understanding of the ecological and biophysical constraints to appreciate why. The act of shooting has turned out not to be of a simple all-or-none character. Rather, the fish adjust the volume of water fired according to target size and use fine adjustments in the timing of their mouth opening and closing manoeuvre to adjust the hydrodynamic stability of their jets to target distance. As soon as prey is dislodged and starts falling, the fish make rapid and yet sophisticated multi-dimensional decisions to secure their prey against many intraspecific and interspecific competitors. Although it is not known why and how archerfish evolved an ability to shoot in the first place, I suggest that the evolution of shooting has strongly pushed the co-evolution of diverse other skills that are needed to secure a catch.
    MeSH term(s) Animals ; Biological Evolution ; Learning ; Perciformes/physiology ; Predatory Behavior ; Visual Perception
    Language English
    Publishing date 2018-12-10
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 218085-6
    ISSN 1477-9145 ; 0022-0949
    ISSN (online) 1477-9145
    ISSN 0022-0949
    DOI 10.1242/jeb.159723
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2629: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    ab Jg. 2022: Lesesaal (EG)

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  10. Article ; Online: Efficient high-voltage protection in the electric catfish.

    Welzel, Georg / Schuster, Stefan

    The Journal of experimental biology

    2021  Volume 224, Issue Pt 4

    Abstract: For thousands of years, starting with detailed accounts from ancient Egypt, the African electric catfish ( ...

    Abstract For thousands of years, starting with detailed accounts from ancient Egypt, the African electric catfish (
    Language English
    Publishing date 2021-02-23
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 218085-6
    ISSN 1477-9145 ; 0022-0949
    ISSN (online) 1477-9145
    ISSN 0022-0949
    DOI 10.1242/jeb.239855
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2629: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    ab Jg. 2022: Lesesaal (EG)

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