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  1. Article ; Online: DDS Profile: Maria T. Abreu, MD.

    Abreu, Maria T

    Digestive diseases and sciences

    2019  Volume 64, Issue 12, Page(s) 3375–3376

    MeSH term(s) Career Choice ; Faculty, Medical ; Gastroenterology/education ; Gastroenterology/history ; History, 20th Century ; History, 21st Century
    Language English
    Publishing date 2019-06-28
    Publishing country United States
    Document type Autobiography ; Historical Article ; Journal Article
    ZDB-ID 304250-9
    ISSN 1573-2568 ; 0163-2116
    ISSN (online) 1573-2568
    ISSN 0163-2116
    DOI 10.1007/s10620-019-05795-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Book: Endoscopy in inflammatory bowel disease

    Abreu, Maria T.

    (Gastrointestinal endoscopy clinics of North America ; volume 26, number 4 (October 2016))

    2016  

    Author's details editor Maria T. Abreu
    Series title Gastrointestinal endoscopy clinics of North America ; volume 26, number 4 (October 2016)
    Collection
    Language English
    Size xvi Seiten, Seite 594-759, Illustrationen
    Publisher Elsevier
    Publishing place Philadelphia, Pennsylvania
    Publishing country United States
    Document type Book
    HBZ-ID HT019155188
    ISBN 978-0-323-46310-2 ; 0-323-46310-X
    Database Catalogue ZB MED Medicine, Health

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  3. Article ; Online: JAK1 Inhibition to Treat Crohn's Disease.

    Abreu, Maria T

    The New England journal of medicine

    2023  Volume 388, Issue 21, Page(s) 2005–2009

    MeSH term(s) Humans ; Crohn Disease/drug therapy ; Janus Kinase 1/antagonists & inhibitors
    Chemical Substances JAK1 protein, human (EC 2.7.10.2) ; Janus Kinase 1 (EC 2.7.10.2)
    Language English
    Publishing date 2023-05-24
    Publishing country United States
    Document type Editorial
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMe2301147
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: How Did It Get So Difficult to Care for Patients With Inflammatory Bowel Disease?

    Abreu, Maria T / Kosinski, Lawrence R

    The American journal of gastroenterology

    2024  

    Language English
    Publishing date 2024-04-30
    Publishing country United States
    Document type Journal Article
    ZDB-ID 390122-1
    ISSN 1572-0241 ; 0002-9270
    ISSN (online) 1572-0241
    ISSN 0002-9270
    DOI 10.14309/ajg.0000000000002794
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  5. Article: Combining Biologic Agents in Inflammatory Bowel Disease.

    Abreu, Maria T

    Gastroenterology & hepatology

    2019  Volume 15, Issue 10, Page(s) 549–551

    Language English
    Publishing date 2019-11-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2386402-3
    ISSN 1554-7914
    ISSN 1554-7914
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: DDS Perspective: My Take on Therapeutic Drug Monitoring in IBD.

    Abreu, Maria T

    Digestive diseases and sciences

    2019  Volume 64, Issue 12, Page(s) 3377–3381

    MeSH term(s) Antibodies, Monoclonal, Humanized/blood ; Antibodies, Monoclonal, Humanized/therapeutic use ; Biological Products/blood ; Biological Products/immunology ; Biological Products/therapeutic use ; Drug Hypersensitivity/etiology ; Drug Hypersensitivity/immunology ; Drug Monitoring ; Drug Therapy, Combination ; Gastrointestinal Agents/therapeutic use ; Humans ; Hypersensitivity, Delayed/chemically induced ; Hypersensitivity, Delayed/immunology ; Hypersensitivity, Immediate/chemically induced ; Hypersensitivity, Immediate/immunology ; Inflammatory Bowel Diseases/drug therapy ; Methotrexate/therapeutic use ; Tumor Necrosis Factor Inhibitors/blood ; Tumor Necrosis Factor Inhibitors/immunology ; Tumor Necrosis Factor Inhibitors/therapeutic use ; Ustekinumab/blood ; Ustekinumab/therapeutic use
    Chemical Substances Antibodies, Monoclonal, Humanized ; Biological Products ; Gastrointestinal Agents ; Tumor Necrosis Factor Inhibitors ; vedolizumab (9RV78Q2002) ; Ustekinumab (FU77B4U5Z0) ; Methotrexate (YL5FZ2Y5U1)
    Language English
    Publishing date 2019-10-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 304250-9
    ISSN 1573-2568 ; 0163-2116
    ISSN (online) 1573-2568
    ISSN 0163-2116
    DOI 10.1007/s10620-019-05796-z
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  7. Article ; Online: Updates in mucosal immunology for inflammatory bowel diseases.

    Abreu, Maria T

    Current opinion in gastroenterology

    2018  Volume 34, Issue 6, Page(s) 375–376

    MeSH term(s) Humans ; Immunity, Mucosal ; Inflammatory Bowel Diseases/immunology ; Intestinal Mucosa/immunology
    Language English
    Publishing date 2018-10-15
    Publishing country United States
    Document type Editorial ; Introductory Journal Article
    ZDB-ID 632571-3
    ISSN 1531-7056 ; 0267-1379
    ISSN (online) 1531-7056
    ISSN 0267-1379
    DOI 10.1097/MOG.0000000000000484
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  8. Article: Current and Novel Uses of Intestinal Ultrasound in Inflammatory Bowel Disease.

    Dolinger, Michael T / Calabrese, Emma / Pizzolante, Fabrizio / Abreu, Maria T

    Gastroenterology & hepatology

    2023  Volume 19, Issue 8, Page(s) 447–457

    Abstract: Intestinal ultrasound (IUS) is a patient-centric, noninvasive, real-time, point-of-care tool with the capability to aid in diagnosis and monitoring of disease activity in both Crohn's disease and ulcerative colitis without the need for bowel preparation. ...

    Abstract Intestinal ultrasound (IUS) is a patient-centric, noninvasive, real-time, point-of-care tool with the capability to aid in diagnosis and monitoring of disease activity in both Crohn's disease and ulcerative colitis without the need for bowel preparation. IUS can be used as a tool for precision monitoring of inflammatory bowel disease (IBD) treatment response. IUS as a cross-sectional imaging tool is as accurate as magnetic resonance enterography (MRE) for assessing the ileum and is more accurate than MRE for colonic assessment proximal to the rectum. Multiple simple ultrasound-based scoring systems have been internally validated with endoscopy in both Crohn's disease and ulcerative colitis, and changes in IUS parameters can be seen as early as 2 weeks after treatment initiation. IUS also plays a unique role in IBD activity monitoring of patients in whom avoidance of invasive testing is paramount, such as children and pregnant patients. Novel uses go beyond monitoring activity, with potential use of elastography to measure bowel wall stiffness to detect fibrosis and bowel damage for enhanced decision-making. Ultimately, IUS is likely to expand in the United States, facilitated by accessible expert training, access to equipment, and the development of a reimbursement model. This article provides a comprehensive review of the current and novel uses of IUS in IBD.
    Language English
    Publishing date 2023-09-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2386402-3
    ISSN 1554-7914
    ISSN 1554-7914
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  9. Article ; Online: Are patients with ulcerative colitis still at increased risk of colon cancer?

    Damas, Oriana M / Abreu, Maria T

    Lancet (London, England)

    2020  Volume 395, Issue 10218, Page(s) 92–94

    MeSH term(s) Cohort Studies ; Colitis, Ulcerative ; Colonic Neoplasms ; Colorectal Neoplasms ; Humans
    Language English
    Publishing date 2020-01-05
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 3306-6
    ISSN 1474-547X ; 0023-7507 ; 0140-6736
    ISSN (online) 1474-547X
    ISSN 0023-7507 ; 0140-6736
    DOI 10.1016/S0140-6736(19)33225-8
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  10. Article ; Online: Pattern Recognition Receptor Signaling and Cytokine Networks in Microbial Defenses and Regulation of Intestinal Barriers: Implications for Inflammatory Bowel Disease.

    Abraham, Clara / Abreu, Maria T / Turner, Jerrold R

    Gastroenterology

    2022  Volume 162, Issue 6, Page(s) 1602–1616.e6

    Abstract: Inflammatory bowel disease is characterized by defects in epithelial function and dysregulated inflammatory signaling by lamina propria mononuclear cells including macrophages and dendritic cells in response to microbiota. In this review, we focus on the ...

    Abstract Inflammatory bowel disease is characterized by defects in epithelial function and dysregulated inflammatory signaling by lamina propria mononuclear cells including macrophages and dendritic cells in response to microbiota. In this review, we focus on the role of pattern recognition receptors in the inflammatory response as well as epithelial barrier regulation. We explore cytokine networks that increase inflammation, regulate paracellular permeability, cause epithelial damage, up-regulate epithelial proliferation, and trigger restitutive processes. We focus on studies using patient samples as well as speculate on pathways that can be targeted to more holistically treat patients with inflammatory bowel disease.
    MeSH term(s) Caco-2 Cells ; Cytokines/metabolism ; Epithelial Cells/metabolism ; Humans ; Inflammatory Bowel Diseases/metabolism ; Intestinal Mucosa/metabolism ; Intestines ; Myosin-Light-Chain Kinase/metabolism ; Permeability ; Tight Junctions/metabolism
    Chemical Substances Cytokines ; Myosin-Light-Chain Kinase (EC 2.7.11.18)
    Language English
    Publishing date 2022-02-09
    Publishing country United States
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural
    ZDB-ID 80112-4
    ISSN 1528-0012 ; 0016-5085
    ISSN (online) 1528-0012
    ISSN 0016-5085
    DOI 10.1053/j.gastro.2021.12.288
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