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  1. Article: Pandemic H1N1 influenza virus triggers a strong T helper cell response in human nasopharynx-associated lymphoid tissues.

    Mahallawi, Waleed H / Khabour, Omar F

    Saudi journal of biological sciences

    2024  Volume 31, Issue 3, Page(s) 103941

    Abstract: The pH1N1 belongs to influenza A family that is sometimes transmitted to humans via contact with pigs. Human tonsillar immune cells are widely used ... ...

    Abstract The pH1N1 belongs to influenza A family that is sometimes transmitted to humans via contact with pigs. Human tonsillar immune cells are widely used as
    Language English
    Publishing date 2024-01-28
    Publishing country Saudi Arabia
    Document type Journal Article
    ZDB-ID 2515206-3
    ISSN 2213-7106 ; 1319-562X
    ISSN (online) 2213-7106
    ISSN 1319-562X
    DOI 10.1016/j.sjbs.2024.103941
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Investigation of the association of the

    Alquraan, Khloud M / Khabour, Omar F

    Romanian journal of internal medicine = Revue roumaine de medecine interne

    2023  Volume 61, Issue 3, Page(s) 154–162

    Abstract: Introduction: Venous thromboembolism (VTE) is the third most common hemostatic disease worldwide. Studies have reported a role for microRNA (miRNA) in the homeostasis and development of VTE. The ras-related nuclear protein (: Methods: The study ... ...

    Abstract Introduction: Venous thromboembolism (VTE) is the third most common hemostatic disease worldwide. Studies have reported a role for microRNA (miRNA) in the homeostasis and development of VTE. The ras-related nuclear protein (
    Methods: The study sample consisted of 300 subjects (150 patients and 150 age and sex matched controls). The polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) and tetra-primer amplification refractory mutation system (T-ARMS) techniques were used to genotype rs14035 and rs11077, respectively.
    Results: The results showed that there was a significant association between the
    Conclusion: The
    MeSH term(s) Humans ; Case-Control Studies ; Genetic Predisposition to Disease ; Genotype ; Karyopherins/genetics ; MicroRNAs/genetics ; Polymorphism, Single Nucleotide ; ran GTP-Binding Protein/genetics ; ran GTP-Binding Protein/metabolism ; Venous Thromboembolism/genetics
    Chemical Substances Karyopherins ; MicroRNAs ; ran GTP-Binding Protein (EC 3.6.5.2) ; XPO5 protein, human ; RAN protein, human
    Language English
    Publishing date 2023-06-13
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2015966-3
    ISSN 2501-062X ; 0035-3973 ; 1582-3296
    ISSN (online) 2501-062X
    ISSN 0035-3973 ; 1582-3296
    DOI 10.2478/rjim-2023-0014
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 738: Show issues Location:
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    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: Vitamin B12 Protects Against Genotoxicity Induced by Cisplatin.

    Al-Bataineh, Wejdan M / Alzoubi, Karem H / Khabour, Omar F / Mahasneh, Amjad / Almomani, Enaam M

    Current cancer drug targets

    2024  

    Abstract: Background: Cisplatin is an effective synthetic chemotherapeutic drug used for cancer treatment. Vitamin B12 has been shown to possess anti-genotoxic activity. This study aimed to investigate the effect of vitamin B12 on chromosomal damage induced by ... ...

    Abstract Background: Cisplatin is an effective synthetic chemotherapeutic drug used for cancer treatment. Vitamin B12 has been shown to possess anti-genotoxic activity. This study aimed to investigate the effect of vitamin B12 on chromosomal damage induced by cisplatin.
    Methods: The level of sister chromatid exchanges (SCEs) and chromosomal aberrations (CAs) were measured in cultured human blood lymphocytes treated with cisplatin and/or vitamin B12.
    Results: The results showed a significantly elevated frequency of CAs and SCEs of cisplatin-treated cultures compared to the control (P < 0.05). The CAs and SCEs induced by cisplatin were significantly lowered by pretreatment of cell cultures with vitamin B12. In addition, cisplatin caused a slight reduction in the mitotic index (MI), while vitamin B12 did not modulate the effect of cisplatin on MI.
    Conclusion: Vitamin B12 can protect human lymphocytes against genotoxicity associated with cisplatin.
    Language English
    Publishing date 2024-01-30
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2064824-8
    ISSN 1873-5576 ; 1568-0096
    ISSN (online) 1873-5576
    ISSN 1568-0096
    DOI 10.2174/0115680096284684240110044954
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5589: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article: The Impact of COVID-19 Confinement on Reading Behavior.

    Alomari, Mahmoud A / Khabour, Omar F / Alzoubi, Karem H / Aburub, Aseel

    Clinical practice and epidemiology in mental health : CP & EMH

    2023  Volume 19, Page(s) e174501792304260

    Abstract: Background: The COVID-19 pandemic was detrimental to lifestyle and behavior. In this investigation, changes in reading habits during the pandemic were examined.: Methods: The study is cross-sectional and survey-based. 1844 individuals completed an ... ...

    Abstract Background: The COVID-19 pandemic was detrimental to lifestyle and behavior. In this investigation, changes in reading habits during the pandemic were examined.
    Methods: The study is cross-sectional and survey-based. 1844 individuals completed an online survey about sociodemographic and reading habits during COVID-19. Multinomial logistic regression was used to examine the relationship between the study variables.
    Results: Most of the participants were active readers (71.5%-83.2%). Fewer (13.8-18.0%) reported a decrease in reading, while about half reported a no change, and 1/3
    Conclusion: About half of the participants during the pandemic reported a change in reading habits. Interventions to further enhance reading among people during the pandemic might help ameliorate the negative impacts of the pandemic.
    Language English
    Publishing date 2023-06-05
    Publishing country United Arab Emirates
    Document type Journal Article
    ZDB-ID 2559748-6
    ISSN 1745-0179
    ISSN 1745-0179
    DOI 10.2174/17450179-v19-e230505-2022-42
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  5. Article ; Online: Coriandrum sativum

    Khabour, Omar F / Abuhammad, Sawsan / Alzoubi, Karem H / Alkofahi, Ahmad S

    Current cancer drug targets

    2023  Volume 24, Issue 4, Page(s) 455–462

    Abstract: Aim: The aim of this study is to examine the protective properties of : Methods: The skin cancer balb/c mouse model was utilized in the study. Plant extracts were administered to animals using oral gavage. In addition, skin cancer was induced using 7, ...

    Abstract Aim: The aim of this study is to examine the protective properties of
    Methods: The skin cancer balb/c mouse model was utilized in the study. Plant extracts were administered to animals using oral gavage. In addition, skin cancer was induced using 7,12-dimethylbenz( a) anthracene (DMBA).
    Results: The study found that
    Conclusion: The findings of this study revealed that
    MeSH term(s) Animals ; Coriandrum/chemistry ; Plant Extracts/pharmacology ; Mice, Inbred BALB C ; Mice ; 9,10-Dimethyl-1,2-benzanthracene/toxicity ; Skin Neoplasms/prevention & control ; Skin Neoplasms/chemically induced ; Skin Neoplasms/pathology ; Skin Neoplasms/drug therapy ; Female ; Plant Leaves/chemistry ; Male ; Disease Models, Animal
    Chemical Substances Plant Extracts ; 9,10-Dimethyl-1,2-benzanthracene (57-97-6)
    Language English
    Publishing date 2023-08-12
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2064824-8
    ISSN 1873-5576 ; 1568-0096
    ISSN (online) 1873-5576
    ISSN 1568-0096
    DOI 10.2174/1568009623666230817101757
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5589: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: The impact of COVID-19 pandemic on tobacco use: A population-based study.

    Alomari, Mahmoud A / Khabour, Omar F / Alzoubi, Karem H / Maikano, Abubakar B

    PloS one

    2023  Volume 18, Issue 6, Page(s) e0287375

    Abstract: Background: Various aspects of lifestyle seem to change during confinement, particularly during the COVID-19 pandemic. The current study examines confinement's effects on tobacco smoking habits (SH).: Methods: A survey was distributed among adults ... ...

    Abstract Background: Various aspects of lifestyle seem to change during confinement, particularly during the COVID-19 pandemic. The current study examines confinement's effects on tobacco smoking habits (SH).
    Methods: A survey was distributed among adults living in Jordan (age >18 years) of both genders during April-May of 2020, of which 1925 responded to the survey.
    Results: The prevalence of smoking was 33.3%, 46.1%, and 21.1% for cigarettes (Cg), waterpipe (Wp), and E-cigarettes (ECg), respectively. Among the smokers, 38.5-45.8% reported a "no-change," while 32.1-41.7% reported a "decrease" in SH during confinement. On the other hand, 18.0-22.1% reported an "increase" in the SH. However, concerning the factors that might affect SH, the results showed that age, gender, income, and job sector contribute to the observed changes.
    Conclusions: Changes in the SH during COVID-19 have been reported in about 50% of participants who smoke tobacco, with a more reported decrease than increase in use. Studies and interventions are needed to confirm further and understand the current results and discourage smoking during the COVID-19 pandemic.
    MeSH term(s) Adult ; Humans ; Male ; Female ; Adolescent ; Electronic Nicotine Delivery Systems ; Pandemics ; COVID-19/epidemiology ; Tobacco Products ; Tobacco Use/epidemiology
    Language English
    Publishing date 2023-06-23
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0287375
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  7. Article ; Online: Associations between rs2241766 and rs3774261 polymorphisms in ADIPOQ gene and atopic dermatitis.

    Al-Shaheri, Fawaz / Khabour, Omar F

    Acta biochimica Polonica

    2022  Volume 69, Issue 3, Page(s) 637–677

    Abstract: Atopic dermatitis (AD) is a common skin condition that affects both children and adults. Adipokines have been shown to play a role in the pathogenesis of AD. In the current study, the association between adiponectin gene (ADIPOQ) polymorphisms and AD was ...

    Abstract Atopic dermatitis (AD) is a common skin condition that affects both children and adults. Adipokines have been shown to play a role in the pathogenesis of AD. In the current study, the association between adiponectin gene (ADIPOQ) polymorphisms and AD was investigated. In addition, changes in serum adiponectin levels in AD patients were examined. Restriction fragment length polymorphism-PCR technique was used to genotype ADIPOQ SNPs. The ELISA assay was used to measure serum Adiponectin levels. A total of 324 participants (162 AD and 162 healthy controls) were included in the study. The frequency of the GG genotype of rs3774261 was higher in the AD group (44.5%) than in the control group (32.7%, P<0.05). Regarding the rs2241766 SNP, the frequency of the GG genotype was higher in the AD group (10.5%) than in the control group (3.1%), while the frequency of the TT genotype was lower (P<0.001) in the AD group (35.8%) than the control group (57.4%). Moreover, the GG haplotype of rs3774261 and rs2241766 significantly increased the risk of AD by about 2-fold (P<0.05). Finally, serum adiponectin levels were lower in the AD group than in the control group (P<0.05). These results indicate an association of the rs2241766 and rs3774261 SNPs with the risk of developing AD among the population examined.
    MeSH term(s) Adiponectin/genetics ; Adult ; Case-Control Studies ; Child ; Dermatitis, Atopic/genetics ; Gene Frequency ; Genetic Predisposition to Disease ; Genotype ; Humans ; Polymorphism, Single Nucleotide
    Chemical Substances ADIPOQ protein, human ; Adiponectin
    Language English
    Publishing date 2022-09-28
    Publishing country Poland
    Document type Journal Article
    ZDB-ID 595762-x
    ISSN 1734-154X ; 0001-527X
    ISSN (online) 1734-154X
    ISSN 0001-527X
    DOI 10.18388/abp.2020_6157
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    In stock of ZB MED Cologne/Königswinter

    Zs.B 232: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: Effect of natural products use prior to infection with COVID-19 on disease severity and hospitalization: A self-reported cross-sectional survey study.

    Nimer, Refat M / Khabour, Omar F / Swedan, Samer F / Kofahi, Hassan M

    F1000Research

    2022  Volume 11, Page(s) 639

    Abstract: Background: ...

    Abstract Background:
    MeSH term(s) Biological Products/therapeutic use ; COVID-19 ; Cross-Sectional Studies ; Hospitalization ; Humans ; SARS-CoV-2 ; Self Report ; Severity of Illness Index
    Chemical Substances Biological Products
    Language English
    Publishing date 2022-06-10
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2699932-8
    ISSN 2046-1402 ; 2046-1402
    ISSN (online) 2046-1402
    ISSN 2046-1402
    DOI 10.12688/f1000research.121933.2
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  9. Article ; Online: Understanding Mental Health Status of Syrian Refugee and Jordanian Women: Novel Insights from a Comparative Study.

    Atrooz, Fatin / Aljararwah, Sally Mohammad / Chen, Tzuan A / Khabour, Omar F / Salim, Samina

    International journal of environmental research and public health

    2023  Volume 20, Issue 4

    Abstract: 1) Background: War and displacement are well-known predictors of negative mental health outcomes among affected populations. This is especially relevant for refugees of war, particularly women, who often repress their mental health needs due to family ... ...

    Abstract (1) Background: War and displacement are well-known predictors of negative mental health outcomes among affected populations. This is especially relevant for refugees of war, particularly women, who often repress their mental health needs due to family responsibilities, social stigma, and/or cultural pressures. In this study, we compared the mental health status of urban Syrian refugee women (
    MeSH term(s) Humans ; Female ; Refugees/psychology ; Syria ; Jordan ; Health Status ; Surveys and Questionnaires
    Language English
    Publishing date 2023-02-08
    Publishing country Switzerland
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph20042976
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  10. Article ; Online: Breast Cancer Beliefs and Screening Practices among Syrian Refugee Women and Jordanian Women.

    Atrooz, Fatin / Aljararwah, Sally Mohammad / Acquati, Chiara / Khabour, Omar F / Salim, Samina

    International journal of environmental research and public health

    2023  Volume 20, Issue 4

    Abstract: Despite significant declines in breast cancer (BC) incidence in the West, this disease is widespread in Jordan, where cancer detection occurs at much advanced stages. This is particularly concerning for Syrian refugee women resettled in Jordan, who are ... ...

    Abstract Despite significant declines in breast cancer (BC) incidence in the West, this disease is widespread in Jordan, where cancer detection occurs at much advanced stages. This is particularly concerning for Syrian refugee women resettled in Jordan, who are less likely to undergo cancer preventative procedures because of poor health literacy and lack of health services access. The present work assesses and compares breast cancer awareness and breast cancer screening behaviors among Syrian refugee women and Jordanian women residing close to the Syrian-Jordanian border city of
    MeSH term(s) Humans ; Female ; Breast Neoplasms ; Refugees ; Jordan ; Syria ; Cross-Sectional Studies ; Early Detection of Cancer
    Language English
    Publishing date 2023-02-18
    Publishing country Switzerland
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph20043645
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