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  1. Article ; Online: Efficacy of electroacupuncture in improving postoperative ileus in patients receiving colorectal surgery: a systematic review and meta-analysis.

    Chen, Hsiao-Tien / Hung, Kuo-Chuan / Huang, Yen-Ta / Wu, Jheng-Yan / Hsing, Chung-Hsi / Lin, Chien-Ming / Chen, I-Wen / Sun, Cheuk-Kwan

    International journal of surgery (London, England)

    2024  Volume 110, Issue 2, Page(s) 1113–1125

    Abstract: Background: This meta-analysis aimed to evaluate the efficacy and safety of electroacupuncture (EA) in improving postoperative ileus after colorectal surgery.: Methods: Electronic databases (e.g. Medline) were screened to identify randomized ... ...

    Abstract Background: This meta-analysis aimed to evaluate the efficacy and safety of electroacupuncture (EA) in improving postoperative ileus after colorectal surgery.
    Methods: Electronic databases (e.g. Medline) were screened to identify randomized controlled trials that focused on the association between EA and postoperative ileus. Time to first flatus served as the primary outcome, while the secondary outcomes included time required for the recovery of other gastrointestinal functions (e.g. bowel sound recovery), time to tolerability of liquid/solid food, postoperative pain scores, risk of overall complications, and hospital length of stay.
    Results: Our meta-analysis focusing on 16 studies with a total of 1562 patients demonstrated positive associations of EA with shorter times to the first flatus [mean difference (MD): -10.1 h, P <0.00001, n =1562], first defecation (MD: -11.77 h, P <0.00001, n =1231), bowel sound recovery (MD: -10.76 h, P <0.00001, n =670), tolerability of liquid (MD: -16.44 h, P =0.0002, n =243), and solid food (MD: -17.21 h, P =0.005, n =582) than those who received standard care. The use of EA was also correlated with a lower risk of overall complications (risk ratio:0.71, P =0.04, n =1011), shorter hospital length of stay (MD: -1.22 days, P =0.0001, n =988), and a lower pain score on postoperative days two (standardized MD: -0.87, P =0.009, n =665) and three (standardized MD: -0.45, P <0.00001, n =795), without a difference in time to first ambulation.
    Conclusion: Our findings showed an association between EA and enhanced gastrointestinal functional recovery and reduced pain severity following colorectal surgery, highlighting the potential benefits of incorporating EA into perioperative care to enhance recovery outcomes in this setting.
    MeSH term(s) Humans ; Electroacupuncture/adverse effects ; Colorectal Surgery/adverse effects ; Flatulence ; Postoperative Complications/etiology ; Postoperative Complications/prevention & control ; Ileus/etiology ; Ileus/prevention & control
    Language English
    Publishing date 2024-02-01
    Publishing country United States
    Document type Meta-Analysis ; Systematic Review ; Journal Article
    ZDB-ID 2212038-5
    ISSN 1743-9159 ; 1743-9191
    ISSN (online) 1743-9159
    ISSN 1743-9191
    DOI 10.1097/JS9.0000000000000848
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: The clinical outcomes and effectiveness of antiviral agents among underweight patients with COVID-19.

    Wu, Jheng-Yan / Liu, Mei-Yuan / Lee, Mei-Chuan / Hung, Kuo-Chuan / Hsu, Wan-Hsuan / Tsai, Ya-Wen / Liu, Ting-Hui / Huang, Po-Yu / Chuang, Min-Hsiang / Tseng, Shu-Ching / Lu, Chih-Ying / Lai, Chih-Cheng

    Expert review of anti-infective therapy

    2024  , Page(s) 1–10

    Abstract: Objectives: This study investigated the outcomes of underweight patients with COVID-19 and the effectiveness of antiviral agents in this population.: Methods: A retrospective cohort study using theTriNetX research network was conducted. Propensity ... ...

    Abstract Objectives: This study investigated the outcomes of underweight patients with COVID-19 and the effectiveness of antiviral agents in this population.
    Methods: A retrospective cohort study using theTriNetX research network was conducted. Propensity score matching (PSM) was employed to balance the first cohort involving COVID-19 patients with underweight and normal-weight. In the second cohort, underweight patients receiving antiviral agents and untreated individuals were matched using PSM. The primary outcome was a composite of all-cause hospitalization and death during the 7-30-day follow-up period.
    Results: After PSM, the first cohort including each group of 13,502 patients with balanced baseline characteristics were identified for comparing the outcome of patients with underweight and normal weight. The underweight group had a higher risk of the composite primary outcome than those with normal weight (hazard ratio [HR], 1.251; 95% confidence interval [CI], 1.132-1.382). The second cohort included each 884 underweight patients with and without receiving antivirals.Compared with untreated patients, those receiving antiviral treatment had a lower risk of composite primary outcomes (HR, 0.426; 95% CI, 0.278-0.653).
    Conclusion: Underweight status may be associated with a higher risk of all-cause hospitalization and death in patients with COVID-19.Among underweight patients, antiviral agents demonstrated clinically beneficial effects.
    Language English
    Publishing date 2024-01-04
    Publishing country England
    Document type Journal Article
    ZDB-ID 2181279-2
    ISSN 1744-8336 ; 1478-7210
    ISSN (online) 1744-8336
    ISSN 1478-7210
    DOI 10.1080/14787210.2024.2303017
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Diagnostic efficacy of sonographic measurement of laryngeal air column width difference for predicting the risk of post-extubation stridor: A meta-analysis of observational studies.

    Tsai, Wen-Wen / Hung, Kuo-Chuan / Huang, Yen-Ta / Yu, Chia-Hung / Lin, Chien-Hung / Chen, I-Wen / Sun, Cheuk-Kwan

    Frontiers in medicine

    2023  Volume 10, Page(s) 1109681

    Abstract: Background: This meta-analysis aimed at assessing the diagnostic accuracy of ultrasound-measured laryngeal air column width difference (ACWD) in predicting post-extubation stridor (PES) in intubated adult patients.: Methods: We searched the Medline, ... ...

    Abstract Background: This meta-analysis aimed at assessing the diagnostic accuracy of ultrasound-measured laryngeal air column width difference (ACWD) in predicting post-extubation stridor (PES) in intubated adult patients.
    Methods: We searched the Medline, Cochrane Library, EMBASE, and Google scholar databases from inception to October, 2022 to identify studies that examined the diagnostic accuracy of ACWD for PES. The primary outcome was the diagnostic performance by calculating the pooled sensitivity, specificity, and area under the curve (AUC). The secondary outcomes were the differences in ACWD and duration of intubation between patients with and without PES.
    Results: Following literature search, 11 prospective studies (intensive care setting,
    Conclusion: Ultrasound-measured laryngeal ACWD showed satisfactory sensitivity and specificity for predicting PES. Because of the limited number of studies available, further investigations are needed to support our findings.
    Systematic review registration: https://www.crd.york.ac.uk/prospero/, identifier CRD42022375772.
    Language English
    Publishing date 2023-01-19
    Publishing country Switzerland
    Document type Systematic Review
    ZDB-ID 2775999-4
    ISSN 2296-858X
    ISSN 2296-858X
    DOI 10.3389/fmed.2023.1109681
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: A new formula to predict the size and insertion depth of cuffed nasotracheal tube in children receiving dental surgery: a retrospective study.

    Chou, Chen-Hung / Tsai, Chia-Ling / Lin, Kai-Lieh / Wu, Shao-Chun / Chiang, Min-Hsien / Huang, Hui-Wen / Hung, Kuo-Chuan

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 12585

    Abstract: This retrospective study aimed to develop a new formula for selecting the appropriate size and determining the depth of the cuffed nasotracheal intubation (NTI) for a cuffed endotracheal tube (cETT) in pediatric patients undergoing dental surgery. In ... ...

    Abstract This retrospective study aimed to develop a new formula for selecting the appropriate size and determining the depth of the cuffed nasotracheal intubation (NTI) for a cuffed endotracheal tube (cETT) in pediatric patients undergoing dental surgery. In addition, the clinical data on cETT (i.e., the size and depth of insertion) was compared with those calculated with age-based formulas to evaluate their correlation. A total number of 684 patients who received NTI were enrolled (healthy group, n = 607; special-need group, n = 77). The ETT size used in real-world scenarios was smaller (i.e., about 0.5 and 0.94 mm) than the age-based formula, while the ETT depth was greater (i.e., about 1.5 cm) than the age-based formula in both groups. In the healthy group, age, gender, and body weight were identified as predictors of ETT size and depth through multiple linear regression analysis, while only age and body weight were predictors in the special-needs group. New formulas were developed based on these findings, with ETT size = 3.98 + 0.052 × age + 0.048 × gender (male = 1, female = 0) + 0.023 × body weight (kg) and ETT depth = 15.1 + 0.43 × age + 0.300 × gender (male = 1, female = 0) + 0.007 × body weight (kg). The new formula could be useful for both healthy and special-need pediatric populations undergoing dental procedures.
    MeSH term(s) Humans ; Child ; Male ; Female ; Infant, Newborn ; Infant ; Retrospective Studies ; Intubation, Intratracheal/adverse effects ; Intubation, Intratracheal/methods ; Body Weight ; Linear Models
    Language English
    Publishing date 2023-08-03
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-39793-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Isolated Primary Neurolymphomatosis in the Right Brachial Plexus Proven by Partial Nerve Biopsy.

    Lee, Gin Hoong / Hsueh, Hsueh-Wen / Wang, Kuo-Chuan / Yu, Shan-Chi / Huang, Hsin-Yi / Chao, Chi-Chao / Hsieh, Sung-Tsang

    The neurologist

    2023  Volume 28, Issue 4, Page(s) 247–249

    Abstract: Introduction: Isolated primary neurolymphomatosis is a rare manifestation of lymphoma, which is challenging to diagnose as there is only involvement of the nervous system, and nerve biopsy is not frequently pursued due to the high risk of irreversible ... ...

    Abstract Introduction: Isolated primary neurolymphomatosis is a rare manifestation of lymphoma, which is challenging to diagnose as there is only involvement of the nervous system, and nerve biopsy is not frequently pursued due to the high risk of irreversible complications.
    Case report: We present a case of isolated primary neurolymphomatosis of diffuse large B-cell lymphoma restricted to only the right brachial plexus and right axillary nerve. The clinical course has been indolent for several years. The initial examination, including MRI and the cerebrospinal fluid study, did not yield any evidence of malignancy. Eventually, due to the patient's symptom progression and the follow-up imaging findings, we conducted a partial nerve biopsy of the brachial plexus to confirm the malignancy. His neurological symptoms did not further deteriorate post-biopsy.
    Conclusion: Isolated primary neurolymphomatosis with an indolent course is rare and challenging to diagnose. Serial MRI and fluorodeoxyglucose-positron emission tomography reveal clues for tumor involvement. Partial nerve biopsy or targeted fascicular nerve biopsy could be an alternative for achieving a pathologic diagnosis.
    MeSH term(s) Humans ; Neurolymphomatosis/diagnostic imaging ; Brachial Plexus/diagnostic imaging ; Brachial Plexus/pathology ; Lymphoma, Large B-Cell, Diffuse/diagnostic imaging ; Positron-Emission Tomography ; Biopsy
    Language English
    Publishing date 2023-07-01
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 1361380-7
    ISSN 2331-2637 ; 1074-7931
    ISSN (online) 2331-2637
    ISSN 1074-7931
    DOI 10.1097/NRL.0000000000000471
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: The efficacy of Perfusion Index for identifying failed nerve block in patients receiving upper extremity surgery: a meta-analysis.

    Hung, Kuo-Chuan / Liu, Chien-Cheng / Huang, Yen-Ta / Chen, Jen-Yin / Chen, Hsiao-Tien / Wang, Kuei-Fen / Hsing, Chung-Hsi / Chen, I-Wen

    Minerva anestesiologica

    2023  Volume 90, Issue 4, Page(s) 311–320

    Abstract: Introduction: Nerve block success is commonly assessed through a variety of techniques, including testing sensations for temperature over the relevant dermatomes and evaluating pain response (e.g., pin-prick). This meta-analysis aimed to investigate the ...

    Abstract Introduction: Nerve block success is commonly assessed through a variety of techniques, including testing sensations for temperature over the relevant dermatomes and evaluating pain response (e.g., pin-prick). This meta-analysis aimed to investigate the diagnostic efficacy of Perfusion Index (PI) in identifying failed nerve blocks in patients undergoing upper extremity surgery.
    Evidence acquisition: A literature search was conducted using four databases, including Medline (OVID), Google Scholar, EMBASE (OVID), and the Cochrane Database of Systematic Reviews, to identify relevant studies from the inception of the databases until June 2023. The main purpose of this study was to evaluate the diagnostic accuracy of PI values and PI ratios in identifying failed nerve blocks.
    Evidence synthesis: Nine studies (published from 2006 to 2022) involving 533 participants (age ranged from 31 to 52 years) were included. The failure rate of nerve blocks ranged from 0% to 18.9%. Pooled results demonstrated promising diagnostic accuracy when using PI values as a predictor of failed nerve block (sensitivity, 77%; specificity, 88.1%; diagnostic odds ratio [DOR], 30.585). Additionally, the analysis of PI ratios as a diagnostic measure showed even higher diagnostic efficacy than using PI values alone, with a sensitivity of 82.9%, specificity of 93.1%, and DOR of 74.543.
    Conclusions: Our meta-analysis confirmed that the PI values and ratios are promising objective predictors of nerve block failure. The simplicity of these techniques supports their feasibility for routine clinical practice. Further studies focusing on different patient populations, such as pregnant women or the elderly, are needed to validate and expand upon our findings.
    MeSH term(s) Humans ; Nerve Block/methods ; Upper Extremity/surgery ; Treatment Failure ; Perfusion Index
    Language English
    Publishing date 2023-11-21
    Publishing country Italy
    Document type Journal Article ; Meta-Analysis ; Systematic Review
    ZDB-ID 123584-9
    ISSN 1827-1596 ; 0026-4717 ; 0375-9393
    ISSN (online) 1827-1596
    ISSN 0026-4717 ; 0375-9393
    DOI 10.23736/S0375-9393.23.17655-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Clinical effectiveness of oral antiviral agents for treating non-hospitalized COVID-19 patients with chronic kidney disease.

    Chen, Chia-Chen / Huang, Chi-Ya / Wu, Jheng-Yan / Liu, Mei-Yuan / Chuang, Min-Hsiang / Liu, Ting-Hui / Tsai, Ya-Wen / Hsu, Wan-Hsuan / Huang, Po-Yu / Chen, Ming-Hui / Liu, Su-Yen / Lee, Mei-Chuan / Hung, Kuo-Chuan / Lai, Chih-Cheng / Yang, I-Ning

    Expert review of anti-infective therapy

    2024  , Page(s) 1–8

    Abstract: Objectives: This study examined the effectiveness of nirmatrelvir plus ritonavir (NMV-r) and molnupiravir (MOV) in treating COVID-19 among chronic kidney disease (CKD) patients.: Methods: This retrospective cohort study, using the TriNetX research ... ...

    Abstract Objectives: This study examined the effectiveness of nirmatrelvir plus ritonavir (NMV-r) and molnupiravir (MOV) in treating COVID-19 among chronic kidney disease (CKD) patients.
    Methods: This retrospective cohort study, using the TriNetX research network, identified stage 3-5 CKD and end-stage kidney disease (ESKD) patients with non-hospitalized COVID-19 between 1 January 2022, and 31 May 2023. Propensity score matching (PSM) was used to compare patients on NMV-r or MOV (antiviral group) against those not receiving these treatments (control group). The primary composite outcome was the cumulative hazard ratio (HR) for all-cause hospitalization or death within the 30-day follow-up.
    Results: After PSM, two balanced cohorts of 6,275 patients each were established. The antiviral group exhibited a lower incidence of all-cause hospitalization or mortality (5.93% vs. 9.53%; HR: 0.626; 95% CI: 0.550-0.713) than controls. Additionally, antiviral recipients were associated with a lower risk of all-cause hospitalization (HR: 0.679; 95% CI: 0.594-0.777) and mortality (HR: 0.338; 95% CI: 0.227-0.504). The beneficial effects of antiviral agents were consistent across sex, age, vaccination status, antiviral type, and CKD stage.
    Conclusion: Oral antiviral agents could be associated with lower rates of all-cause hospitalization or death among non-hospitalized COVID-19 patients with CKD.
    Language English
    Publishing date 2024-03-26
    Publishing country England
    Document type Journal Article
    ZDB-ID 2181279-2
    ISSN 1744-8336 ; 1478-7210
    ISSN (online) 1744-8336
    ISSN 1478-7210
    DOI 10.1080/14787210.2024.2334052
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Efficacy of the visual cognitive assessment test for mild cognitive impairment/mild dementia diagnosis: a meta-analysis.

    Hsu, Jui-Hung / Liu, Chien-Cheng / Chen, I-Wen / Wu, Jheng-Yan / Huang, Po-Yu / Liu, Ting-Hui / Hung, Kuo-Chuan

    Frontiers in public health

    2023  Volume 11, Page(s) 1293710

    Abstract: Background: Mild cognitive impairment (MCI) is an intermediate stage between normal ageing and dementia. The early identification of MCI is important for timely intervention. The visual cognitive assessment test (VCAT) is a brief language-neutral ... ...

    Abstract Background: Mild cognitive impairment (MCI) is an intermediate stage between normal ageing and dementia. The early identification of MCI is important for timely intervention. The visual cognitive assessment test (VCAT) is a brief language-neutral screening tool for detecting MCI/mild dementia. This meta-analysis evaluated the diagnostic efficacy of the VCAT for MCI/mild dementia.
    Methods: Medline, Embase, Google Scholar, and Cochrane Library were searched from their inception until August 2023 to identify studies using VCAT to diagnose MCI/mild dementia. The primary outcome was to assess the diagnostic accuracy of the VCAT for detecting MCI/mild dementia through area under the receiver operating characteristic curve (AU-ROC) analysis. The secondary outcome was to explore the correlation between VCAT scores and MCI/mild dementia presence by comparing scores among patients with and without MCI/mild dementia. Pooled sensitivity, specificity, and area under the curve (AUC) were calculated.
    Results: Five studies with 1,446 older adults (mean age 64-68.3 years) were included. The percentage of participants with MCI/mild dementia versus controls ranged from 16.5% to 87% across studies. All studies were conducted in Asian populations, mostly Chinese, in Singapore and Malaysia. The pooled sensitivity was 80% [95% confidence interval (CI) 68%-88%] and the specificity was 75% (95% CI 68%-80%). The AU-ROCC was 0.77 (95% CI 0.73-0.81). Patients with MCI/mild dementia had lower VCAT scores than the controls (mean difference -6.85 points,
    Conclusion: VCAT demonstrated acceptable diagnostic accuracy in distinguishing MCI/mild dementia in cognitively normal older adults. As a language-neutral and culturally unbiased tool, the VCAT shows promise in detecting MCI/mild dementia. Further studies in non-Asian populations are required.
    Systematic review registration: https://www.crd.york.ac.uk/prospero/, identifier: CRD42023453453.
    MeSH term(s) Humans ; Aged ; Middle Aged ; Alzheimer Disease ; Sensitivity and Specificity ; Cognitive Dysfunction/diagnosis ; ROC Curve ; Cognition
    Language English
    Publishing date 2023-10-31
    Publishing country Switzerland
    Document type Meta-Analysis ; Systematic Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2711781-9
    ISSN 2296-2565 ; 2296-2565
    ISSN (online) 2296-2565
    ISSN 2296-2565
    DOI 10.3389/fpubh.2023.1293710
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Comment on: Environmental sustainability in robotic and laparoscopic surgery: systematic review.

    Hung, Chao-Ming / Hung, Kuo-Chuan / Lee, Po-Huang / Lu, Kang / Hsieh, Meng-Che / Chiu, Chong-Chi

    The British journal of surgery

    2022  

    Language English
    Publishing date 2022-11-03
    Publishing country England
    Document type Journal Article
    ZDB-ID 2985-3
    ISSN 1365-2168 ; 0263-1202 ; 0007-1323 ; 1355-7688
    ISSN (online) 1365-2168
    ISSN 0263-1202 ; 0007-1323 ; 1355-7688
    DOI 10.1093/bjs/znac369
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Comment on: Tranexamic acid for safer surgery: the time is now.

    Hung, Chao-Ming / Hung, Kuo-Chuan / Lee, Po-Huang / Tsai, I Ting / Lee, Hui-Ming / Chiu, Chong-Chi

    The British journal of surgery

    2022  Volume 109, Issue 12, Page(s) e130

    Language English
    Publishing date 2022-09-17
    Publishing country England
    Document type Journal Article
    ZDB-ID 2985-3
    ISSN 1365-2168 ; 0263-1202 ; 0007-1323 ; 1355-7688
    ISSN (online) 1365-2168
    ISSN 0263-1202 ; 0007-1323 ; 1355-7688
    DOI 10.1093/bjs/znac331
    Database MEDical Literature Analysis and Retrieval System OnLINE

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