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  1. Article ; Online: Prevalence of gastrointestinal symptoms in autism spectrum disorder: A meta-analysis.

    Lasheras, Isabel / Real-López, Matias / Santabárbara, Javier

    Anales de pediatria

    2023  Volume 99, Issue 2, Page(s) 102–110

    Abstract: Introduction: A high prevalence of gastrointestinal (GI) symptoms has been described in children and adolescents with autism spectrum disorder (ASD). In addition, there is evidence that presence of GI symptoms is associated to greater severity of ASD. ... ...

    Abstract Introduction: A high prevalence of gastrointestinal (GI) symptoms has been described in children and adolescents with autism spectrum disorder (ASD). In addition, there is evidence that presence of GI symptoms is associated to greater severity of ASD. However, the frequency of GI symptoms in children and adolescents with ASD varies widely across studies, and their true prevalence is unknown. Therefore, the objective of this study was to estimate the prevalence of GI symptoms in children and adolescents with ASD.
    Material and method: We conducted a meta-analysis following the PRISMA guidelines. We carried out a rapid systematic search for recent clinical and observational studies published from August 2012 in PubMed. The statistical analyses were performed with the software R.
    Results: Of 91 potentially eligible articles, only 8 met our inclusion criteria. The prevalence of GI symptoms ranged between 0% and 69%, with an estimated general prevalence of 33% (95% CI, 13%-57%), higher than that reported by a previous meta-analysis for the general paediatric population. This difference is even greater in the specific comparison of studies that applied the paediatric version of the ROME III questionnaire (QPGS-ROME III).
    Conclusions: The results confirmed the hypothesis that there is a higher prevalence of functional GI symptoms in paediatric patients with ASD compared to their neurotypical peers.
    MeSH term(s) Adolescent ; Humans ; Child ; Autism Spectrum Disorder/epidemiology ; Prevalence ; Gastrointestinal Diseases/diagnosis ; Gastrointestinal Diseases/epidemiology ; Surveys and Questionnaires
    Language English
    Publishing date 2023-07-18
    Publishing country Spain
    Document type Meta-Analysis ; Journal Article
    ZDB-ID 2830901-7
    ISSN 2341-2879 ; 2341-2879
    ISSN (online) 2341-2879
    ISSN 2341-2879
    DOI 10.1016/j.anpede.2023.07.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Use of antimalarial drugs in the treatment of COVID-19: A window of opportunity?

    Lasheras, Isabel / Santabárbara, Javier

    Medicina clinica (English ed.)

    2020  Volume 155, Issue 1, Page(s) 23–25

    Keywords covid19
    Language English
    Publishing date 2020-05-22
    Publishing country Spain
    Document type Journal Article
    ISSN 2387-0206
    ISSN (online) 2387-0206
    DOI 10.1016/j.medcle.2020.04.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Use of antimalarial drugs in the treatment of COVID-19: A window of opportunity?

    Lasheras, Isabel / Santabárbara, Javier

    Medicina clinica

    2020  Volume 155, Issue 1, Page(s) 23–25

    Title translation Uso de antipalúdicos en el tratamiento del COVID-19: ¿una ventana de oportunidad?
    MeSH term(s) Antimalarials/therapeutic use ; Betacoronavirus ; COVID-19 ; Coronavirus Infections/drug therapy ; Global Health ; Humans ; Pandemics ; Pneumonia, Viral/drug therapy ; SARS-CoV-2 ; Treatment Outcome
    Chemical Substances Antimalarials
    Keywords covid19
    Language Spanish
    Publishing date 2020-04-22
    Publishing country Spain
    Document type Editorial
    ZDB-ID 411607-0
    ISSN 1578-8989 ; 0025-7753
    ISSN (online) 1578-8989
    ISSN 0025-7753
    DOI 10.1016/j.medcli.2020.04.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Use of antimalarial drugs in the treatment of COVID-19

    Lasheras, Isabel / Santabárbara, Javier

    Medicina Clínica (English Edition)

    A window of opportunity?

    2020  Volume 155, Issue 1, Page(s) 23–25

    Keywords covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ISSN 2387-0206
    DOI 10.1016/j.medcle.2020.04.002
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Uso de antipalúdicos en el tratamiento del COVID-19

    Lasheras, Isabel / Santabárbara, Javier

    Medicina Clínica

    ¿una ventana de oportunidad?

    2020  Volume 155, Issue 1, Page(s) 23–25

    Keywords General Medicine ; covid19
    Language Spanish
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ZDB-ID 411607-0
    ISSN 1578-8989 ; 0025-7753
    ISSN (online) 1578-8989
    ISSN 0025-7753
    DOI 10.1016/j.medcli.2020.04.004
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article: Uso de antipalúdicos en el tratamiento del COVID-19: ¿una ventana de oportunidad?/ Uso de antipalúdicos en el tratamiento del COVID-19: ¿una ventana de oportunidad?/ Use of antimalarial drugs in the treatment of COVID-19: A window of opportunity?

    Lasheras, Isabel / Santabárbara, Javier

    Med. clin (Ed. impr.)

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #32386744
    Database COVID19

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  9. Article ; Online: Magnetoelastic Resonance Sensors: Principles, Applications, and Perspectives.

    G Saiz, Paula / Fernández de Luis, Roberto / Lasheras, Andoni / Arriortua, María Isabel / Lopes, Ana Catarina

    ACS sensors

    2022  Volume 7, Issue 5, Page(s) 1248–1268

    Abstract: Magnetoelastic resonators are gaining attention as an incredibly versatile and sensitive transduction platform for the detection of varied physical, chemical, and biological parameters. These sensors, based on the coupling effect between mechanical and ... ...

    Abstract Magnetoelastic resonators are gaining attention as an incredibly versatile and sensitive transduction platform for the detection of varied physical, chemical, and biological parameters. These sensors, based on the coupling effect between mechanical and magnetic properties of ME platforms, stand out in comparison to alternative technologies due to their low cost and wireless detection capability. Several parameters have been optimized over the years to improve their performance, such as their composition, surface functionalization, or shape geometry. In this review, the working principles, recent advances, and future perspectives of magnetoelastic resonance transducers are introduced, highlighting their potentials as a versatile platform for sensing applications. First, the fundamental principles governing the magnetoelastic resonators performance are introduced as well as the most common magnetoelastic materials and their main fabrication methods are described. Second, the versatility and technical feasibility of magnetoelastic resonators for biological, chemical, and physical sensing are highlighted and the most recent results and functionalization processes are summarized. Finally, the forefront advances to further improve the performance of magnetoelastic resonators for sensing applications have been identified.
    MeSH term(s) Biosensing Techniques/methods ; Magnetics ; Transducers
    Language English
    Publishing date 2022-04-22
    Publishing country United States
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ISSN 2379-3694
    ISSN (online) 2379-3694
    DOI 10.1021/acssensors.2c00032
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: The impact of acute energy drink consumption on electrical heart disease: A systematic review and meta-analysis.

    Lasheras, Isabel / Seral, Paloma / Alonso-Ventura, Vanesa / Santabárbara, Javier

    Journal of electrocardiology

    2021  Volume 65, Page(s) 128–135

    Abstract: Aims: Energy Drink (ED)-associated cardiovascular emergency visits have increased in recent years. Although a toxicity threshold has been established for caffeine, the safety profile of whole ED consumption has not yet been defined.: Methods: This ... ...

    Abstract Aims: Energy Drink (ED)-associated cardiovascular emergency visits have increased in recent years. Although a toxicity threshold has been established for caffeine, the safety profile of whole ED consumption has not yet been defined.
    Methods: This systematic review was conducted following the PRISMA guidelines. Three reviewers conducted two separate systematic searches on PubMed on October 24 and December 3, 2019. Out of 250 potential records, 43 prospective clinical studies assessing the effects of ED on heart rate (HR) and/or any electrocardiographic (ECG) parameters were included. A meta-analysis was conducted to estimate pooled p-values using metap command for STATA 10.0.
    Results: After ED consumption, resting HR increased in 71.1% of studies (pooled p-value <0.001) but was only significant in 38%; HR during and after exercise increased in 55.5% (pooled p-value <0.001) and 71.4% of studies, respectively; QRS increased in all but two protocols; evidence on PR interval was contradictory, and corrected QT interval (QTc) increased compared to baseline in all but one study, exceeding the pathological limit value in two of them. T wave changes were seen in two studies, and one study reported a ratio of 5 to 1 in the number of ectopic beats.
    Conclusion: Acute consumption of ED can alter the ECG in certain risk populations, posing a risk whose magnitude is yet to be determined. Caution should be exercised among at-risk and underage individuals but further research in these populations is warranted before restrictions are made.
    Language English
    Publishing date 2021-02-09
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 410286-1
    ISSN 1532-8430 ; 0022-0736
    ISSN (online) 1532-8430
    ISSN 0022-0736
    DOI 10.1016/j.jelectrocard.2021.01.020
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Jg. 1995 - 2021: Lesesall (1.OG)
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