LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 52

Search options

  1. Article ; Online: Tips and Advice on Preparing a Research Manuscript for Submission and Publication in a Peer-Reviewed Stroke Journal.

    Lendaris, Andrea / Esenwa, Charles

    Stroke

    2023  Volume 54, Issue 5, Page(s) e217–e219

    MeSH term(s) Humans ; Publishing ; Peer Review, Research
    Language English
    Publishing date 2023-04-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80381-9
    ISSN 1524-4628 ; 0039-2499 ; 0749-7954
    ISSN (online) 1524-4628
    ISSN 0039-2499 ; 0749-7954
    DOI 10.1161/STROKEAHA.122.037872
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article ; Online: Importance of cerebral angiography in the evaluation of delayed carotid stent thrombosis: a case report.

    Masoud, Zaki / Daza-Ovalle, Juan Felipe / Esenwa, Charles

    Journal of medical case reports

    2024  Volume 18, Issue 1, Page(s) 109

    Abstract: Background: While noninvasive imaging is typically used during the initial assessment of carotid artery disease, digital subtraction angiography remains the gold standard for evaluating carotid stent thrombosis and stenosis (Krawisz in Cardiol Clin 39: ... ...

    Abstract Background: While noninvasive imaging is typically used during the initial assessment of carotid artery disease, digital subtraction angiography remains the gold standard for evaluating carotid stent thrombosis and stenosis (Krawisz in Cardiol Clin 39:539-549, 2021). This case highlights the importance of digital subtraction angiography for assessing carotid artery stent patency in place of non-invasive imaging.
    Case presentation: We present a 61-year-old African American male patient with a history of right cervical internal carotid artery dissection that was treated with carotid artery stenting and endovascular thrombectomy, who developed recurrent right hemispheric infarcts related to delayed carotid stent thrombosis. Digital subtraction angiography found multiple filling defects consistent with extensive in-stent thrombosis not clearly observed with magnetic resonance angiography. Etiology was likely secondary to chronic antiplatelet noncompliance. Therefore, the patient was treated medically with a heparin drip, and dual antiplatelet therapy (dAPT) was restarted. At 1-month follow-up the patient did not report new motor or sensory deficits.
    Conclusion: In the setting of delayed carotid stent thrombosis secondary to antiplatelet noncompliance, digital subtraction angiography may play an essential diagnostic role for early identification and determination of the most appropriate treatment.
    MeSH term(s) Humans ; Male ; Middle Aged ; Stents/adverse effects ; Carotid Stenosis/diagnostic imaging ; Carotid Stenosis/surgery ; Cerebral Angiography ; Thrombosis/diagnostic imaging ; Thrombosis/etiology ; Carotid Artery, Internal/diagnostic imaging ; Angiography, Digital Subtraction
    Language English
    Publishing date 2024-02-22
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 2269805-X
    ISSN 1752-1947 ; 1752-1947
    ISSN (online) 1752-1947
    ISSN 1752-1947
    DOI 10.1186/s13256-024-04379-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article ; Online: Transforming Posthospital Stroke Care, Outcomes, and Use of New Innovations Through Implementation Science.

    Bettger, Janet Prvu / Nichols, Michelle / Esenwa, Charles / Simpkins, Alexis N

    Journal of the American Heart Association

    2024  Volume 13, Issue 7, Page(s) e031310

    MeSH term(s) Humans ; Implementation Science ; Stroke/epidemiology ; Stroke/therapy ; Patient Discharge ; Stroke Rehabilitation
    Language English
    Publishing date 2024-03-26
    Publishing country England
    Document type Journal Article
    ZDB-ID 2653953-6
    ISSN 2047-9980 ; 2047-9980
    ISSN (online) 2047-9980
    ISSN 2047-9980
    DOI 10.1161/JAHA.123.031310
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Article ; Online: Paging Global Neurology Organizations-The Time Is Now for More Inclusive Leadership.

    Esenwa, Charles / Ovbiagele, Bruce

    JAMA neurology

    2022  Volume 79, Issue 10, Page(s) 964–965

    MeSH term(s) Humans ; Leadership ; Neurology
    Language English
    Publishing date 2022-08-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2702023-X
    ISSN 2168-6157 ; 2168-6149
    ISSN (online) 2168-6157
    ISSN 2168-6149
    DOI 10.1001/jamaneurol.2022.2181
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  5. Article ; Online: A Novel COL4A2 Mutation Associated with Recurrent Strokes.

    McHugh, Daryl C / Esenwa, Charles

    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association

    2020  Volume 29, Issue 10, Page(s) 105156

    Abstract: Mutations in type four collagens, specifically COL4A1 and COL4A2, have been associated with cerebral small vessel disease (SVD), defined as lacunar infarcts, deep intracerebral hemorrhages (ICH), and leukoaraiosis. We present a case of a man with ... ...

    Abstract Mutations in type four collagens, specifically COL4A1 and COL4A2, have been associated with cerebral small vessel disease (SVD), defined as lacunar infarcts, deep intracerebral hemorrhages (ICH), and leukoaraiosis. We present a case of a man with recurrent cerebral infarcts, related to a novel COL4A2 mutation, the p.A1534S variant. Magnetic resonance imaging demonstrated multiple lacunar infarcts, numerous deep and lobar microhemorrhages and advanced leukoaraiosis. Evaluation for COL4A2 mutations should be considered when suspecting a genetic cerebral small vessel disease.
    MeSH term(s) Cerebral Infarction/diagnostic imaging ; Cerebral Infarction/genetics ; Collagen Type IV/genetics ; DNA Mutational Analysis ; Genetic Predisposition to Disease ; Heterozygote ; Humans ; Intracranial Hemorrhages/diagnostic imaging ; Intracranial Hemorrhages/genetics ; Leukoaraiosis/diagnostic imaging ; Leukoaraiosis/genetics ; Male ; Middle Aged ; Mutation ; Phenotype ; Recurrence ; Whole Exome Sequencing
    Chemical Substances COL4A2 protein, human ; Collagen Type IV
    Language English
    Publishing date 2020-07-25
    Publishing country United States
    Document type Case Reports
    ZDB-ID 1131675-5
    ISSN 1532-8511 ; 1052-3057
    ISSN (online) 1532-8511
    ISSN 1052-3057
    DOI 10.1016/j.jstrokecerebrovasdis.2020.105156
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  6. Article ; Online: The effect of COVID-19 on stroke hospitalizations in New York City.

    Esenwa, Charles / Parides, Michael K / Labovitz, Daniel L

    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association

    2020  Volume 29, Issue 10, Page(s) 105114

    Abstract: Background: Little is known about the effect of the Coronavirus disease 2019 pandemic on stroke care and the impact of the epidemic on acute stroke hospitalizations has not been described.: Methods: We analyze the stroke admission rate in three ... ...

    Abstract Background: Little is known about the effect of the Coronavirus disease 2019 pandemic on stroke care and the impact of the epidemic on acute stroke hospitalizations has not been described.
    Methods: We analyze the stroke admission rate in three hospitals in New York City from January 1, 2020 through April 17, 2020, identifying all cases of acute ischemic stroke, intraparenchymal hemorrhage and subarachnoid hemorrhage.
    Results: We confirmed 518 cases of out-of-hospital stroke. During the baseline period up to February 25, 2020, the daily stroke admission rate was stable, with the slope of the regression describing the number of admissions over time equal to -0.33 (se = 1.21), not significantly different from 0 (p = 0.79), with daily admissions averaging 41. During the pandemic period, the slope was -4.4 (se = 1.00); i.e., the number of stroke admissions decreased an average of 4.4 per week, (p = 0.005), with weekly admissions averaging 23, a reduction of 44% versus baseline. This general result was not different by patient age, sex, or race/ethnicity.
    Conclusions: The weekly stroke admission rate started declining two weeks prior to the local surge of coronavirus admissions. The consequences of lack of diagnosis and treatment of a large proportion of acute stroke patients are likely severe and lasting.
    MeSH term(s) Aged ; Betacoronavirus/pathogenicity ; COVID-19 ; Coronavirus Infections/diagnosis ; Coronavirus Infections/epidemiology ; Coronavirus Infections/therapy ; Coronavirus Infections/virology ; Delivery of Health Care/trends ; Female ; Host Microbial Interactions ; Humans ; Intracranial Hemorrhages/diagnosis ; Intracranial Hemorrhages/epidemiology ; Intracranial Hemorrhages/therapy ; Intracranial Hemorrhages/virology ; Male ; Middle Aged ; New York City/epidemiology ; Pandemics ; Patient Admission/trends ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/therapy ; Pneumonia, Viral/virology ; Prognosis ; SARS-CoV-2 ; Stroke/diagnosis ; Stroke/epidemiology ; Stroke/therapy ; Stroke/virology ; Subarachnoid Hemorrhage/epidemiology ; Subarachnoid Hemorrhage/therapy ; Time Factors
    Keywords covid19
    Language English
    Publishing date 2020-07-13
    Publishing country United States
    Document type Journal Article ; Multicenter Study
    ZDB-ID 1131675-5
    ISSN 1532-8511 ; 1052-3057
    ISSN (online) 1532-8511
    ISSN 1052-3057
    DOI 10.1016/j.jstrokecerebrovasdis.2020.105114
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  7. Article ; Online: Trends in diversity, equity and inclusion publications in neurological journals: 2015-2020.

    Esenwa, Charles / Patel, Nikunj K / Etienne, Mill / Drugge, Elizabeth D / Wallace, Emma / Ovbiagele, Bruce

    Journal of the National Medical Association

    2022  

    Abstract: Background: Contemporary information on health equity related efforts by scientific neurological journals, as measured by publications related to diversity, equity and inclusion (DEI) and health disparities related to social determinants of health (SDH) ...

    Abstract Background: Contemporary information on health equity related efforts by scientific neurological journals, as measured by publications related to diversity, equity and inclusion (DEI) and health disparities related to social determinants of health (SDH) are lacking.
    Objective: To assess the yearly rates of DEI and SDH related publications in the highest cited general neurology and neurological sub-specialty journals and compare them to the highest cited medical journals over a 6-year period.
    Methods: We included publications from 15 general neurology and neurological subspecialty journals between January 1
    Results: Total yearly proportion of DEI and SDH related publications in neurological journals was 3.9% compared to 6.2% in the highest cited medical journals for years 2015 to 2020 (p=0.001). There was no change in overall trend in publications related to DEI and SDH topics in neurological (ρ = -0.082, p=0.45) or highest cited medical journals between 2015 and 2020 (ρ = -0.065, p=0.54).
    Conclusion: Neurological journals had a significantly lower yearly proportion of DEI and SDH related publications compared to top-cited medical journals. Despite heightened awareness of racial/ethnic health disparities and inequities driven by SDH there was no change in related publications in neurological journals between 2015-2020.
    Language English
    Publishing date 2022-10-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 419737-9
    ISSN 1943-4693 ; 0027-9684
    ISSN (online) 1943-4693
    ISSN 0027-9684
    DOI 10.1016/j.jnma.2022.09.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  8. Article ; Online: Scoping Review of Racial, Ethnic, and Sex Disparities in the Diagnosis and Management of Hemorrhagic Stroke.

    Kalasapudi, Lakshman / Williamson, Stacey / Shipper, Andrea G / Motta, Melissa / Esenwa, Charles / Otite, Fadar Oliver / Chaturvedi, Seemant / Morris, Nicholas A

    Neurology

    2023  Volume 101, Issue 3, Page(s) e267–e276

    Abstract: Background and objectives: In the United States, Black, Hispanic, and Asian Americans experience excessively high incidence rates of hemorrhagic stroke compared with White Americans. Women experience higher rates of subarachnoid hemorrhage than men. ... ...

    Abstract Background and objectives: In the United States, Black, Hispanic, and Asian Americans experience excessively high incidence rates of hemorrhagic stroke compared with White Americans. Women experience higher rates of subarachnoid hemorrhage than men. Previous reviews detailing racial, ethnic, and sex disparities in stroke have focused on ischemic stroke. We performed a scoping review of disparities in the diagnosis and management of hemorrhagic stroke in the United States to identify areas of disparities, research gaps, and evidence to inform efforts aimed at health equity.
    Methods: We included studies published after 2010 that assessed racial and ethnic or sex disparities in the diagnosis or management of patients aged 18 years or older in the United States with a primary diagnosis of spontaneous intracerebral hemorrhage or aneurysmal subarachnoid hemorrhage. We did not include studies assessing disparities in incidence, risks, or mortality and functional outcomes of hemorrhagic stroke.
    Results: After reviewing 6,161 abstracts and 441 full texts, 59 studies met our inclusion criteria. Four themes emerged. First, few data address disparities in acute hemorrhagic stroke. Second, racial and ethnic disparities in blood pressure control after intracerebral hemorrhage exist and likely contribute to disparities in recurrence rates. Third, racial and ethnic differences in end-of-life care exist, but further work is required to understand whether these differences represent true disparities in care. Fourth, very few studies specifically address sex disparities in hemorrhagic stroke care.
    Discussion: Further efforts are necessary to delineate and correct racial, ethnic, and sex disparities in the diagnosis and management of hemorrhagic stroke.
    MeSH term(s) Female ; Humans ; Male ; Cerebral Hemorrhage/diagnosis ; Cerebral Hemorrhage/epidemiology ; Cerebral Hemorrhage/ethnology ; Cerebral Hemorrhage/therapy ; Healthcare Disparities/ethnology ; Healthcare Disparities/statistics & numerical data ; Hemorrhagic Stroke/diagnosis ; Hemorrhagic Stroke/epidemiology ; Hemorrhagic Stroke/ethnology ; Hemorrhagic Stroke/etiology ; Hemorrhagic Stroke/therapy ; Hispanic or Latino/statistics & numerical data ; Racial Groups/statistics & numerical data ; Stroke/diagnosis ; Stroke/epidemiology ; Stroke/ethnology ; Stroke/therapy ; Subarachnoid Hemorrhage/complications ; Subarachnoid Hemorrhage/diagnosis ; Subarachnoid Hemorrhage/epidemiology ; Subarachnoid Hemorrhage/ethnology ; United States/epidemiology ; Sex Factors ; Race Factors ; Black or African American/statistics & numerical data ; Asian/statistics & numerical data ; White/statistics & numerical data ; Incidence
    Language English
    Publishing date 2023-05-18
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 207147-2
    ISSN 1526-632X ; 0028-3878
    ISSN (online) 1526-632X
    ISSN 0028-3878
    DOI 10.1212/WNL.0000000000207406
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  9. Article ; Online: Historical Redlining, Social Determinants of Health, and Stroke Prevalence in Communities in New York City.

    Jadow, Benjamin M / Hu, Liangyuan / Zou, Jungang / Labovitz, Daniel / Ibeh, Chinwe / Ovbiagele, Bruce / Esenwa, Charles

    JAMA network open

    2023  Volume 6, Issue 4, Page(s) e235875

    Abstract: Importance: Historical redlining was a discriminatory housing policy that placed financial services beyond the reach of residents in inner-city communities. The extent of the impact of this discriminatory policy on contemporary health outcomes remains ... ...

    Abstract Importance: Historical redlining was a discriminatory housing policy that placed financial services beyond the reach of residents in inner-city communities. The extent of the impact of this discriminatory policy on contemporary health outcomes remains to be elucidated.
    Objective: To evaluate the associations among historical redlining, social determinants of health (SDOH), and contemporary community-level stroke prevalence in New York City.
    Design, setting, and participants: An ecological, retrospective, cross-sectional study was conducted using New York City data from January 1, 2014, to December 31, 2018. Data from the population-based sample were aggregated on the census tract level. Quantile regression analysis and a quantile regression forests machine learning model were used to determine the significance and overall weight of redlining in relation to other SDOH on stroke prevalence. Data were analyzed from November 5, 2021, to January 31, 2022.
    Exposures: Social determinants of health included race and ethnicity, median household income, poverty, low educational attainment, language barrier, uninsurance rate, social cohesion, and residence in an area with a shortage of health care professionals. Other covariates included median age and prevalence of diabetes, hypertension, smoking, and hyperlipidemia. Weighted scores for historical redlining (ie, the discriminatory housing policy in effect from 1934 to 1968) were computed using the mean proportion of original redlined territories overlapped on 2010 census tract boundaries in New York City.
    Main outcomes and measures: Stroke prevalence was collected from the Centers for Disease Control and Prevention 500 Cities Project for adults 18 years and older from 2014 to 2018.
    Results: A total of 2117 census tracts were included in the analysis. After adjusting for SDOH and other relevant covariates, the historical redlining score was independently associated with a higher community-level stroke prevalence (odds ratio [OR], 1.02 [95% CI, 1.02-1.05]; P < .001). Social determinants of health that were positively associated with stroke prevalence included educational attainment (OR, 1.01 [95% CI, 1.01-1.01]; P < .001), poverty (OR, 1.01 [95% CI, 1.01-1.01]; P < .001), language barrier (OR, 1.00 [95% CI, 1.00-1.00]; P < .001), and health care professionals shortage (OR, 1.02 [95% CI, 1.00-1.04]; P = .03).
    Conclusions and relevance: This cross-sectional study found that historical redlining was associated with modern-day stroke prevalence in New York City independently of contemporary SDOH and community prevalence of some relevant cardiovascular risk factors.
    MeSH term(s) Adult ; Humans ; New York City ; Social Determinants of Health ; Retrospective Studies ; Cross-Sectional Studies ; Prevalence ; Stroke
    Language English
    Publishing date 2023-04-03
    Publishing country United States
    Document type Journal Article
    ISSN 2574-3805
    ISSN (online) 2574-3805
    DOI 10.1001/jamanetworkopen.2023.5875
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  10. Article ; Online: "Basilar Web" Causing Basilar Branch Infarction.

    Esenwa, Charles / Labovitz, Daniel / Caplan, Louis R

    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association

    2019  Volume 28, Issue 11, Page(s) 104366

    Abstract: We present a young patient with no vascular risk factors with a basilar branch infarction secondary to a shelf-like filling defect of the basilar artery. This defect was present and unchanged on repeat imaging and determined to be most consistent with a ... ...

    Abstract We present a young patient with no vascular risk factors with a basilar branch infarction secondary to a shelf-like filling defect of the basilar artery. This defect was present and unchanged on repeat imaging and determined to be most consistent with a basilar web. Similar to carotid webs, a basilar web is believed to be an area of focal intimal fibroplasia that increases the risk of brainstem infarction. Focal fibroplasia of the posterior circulation should be considered when evaluating young adults with posterior circulation strokes of otherwise undetermined cause.
    MeSH term(s) Basilar Artery/diagnostic imaging ; Basilar Artery/pathology ; Brain Stem Infarctions/diagnostic imaging ; Brain Stem Infarctions/etiology ; Brain Stem Infarctions/pathology ; Female ; Fibromuscular Dysplasia/complications ; Fibromuscular Dysplasia/diagnostic imaging ; Fibromuscular Dysplasia/pathology ; Fibrosis ; Humans ; Hyperplasia ; Pons/blood supply ; Risk Factors ; Young Adult
    Language English
    Publishing date 2019-09-09
    Publishing country United States
    Document type Case Reports
    ZDB-ID 1131675-5
    ISSN 1532-8511 ; 1052-3057
    ISSN (online) 1532-8511
    ISSN 1052-3057
    DOI 10.1016/j.jstrokecerebrovasdis.2019.104366
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top