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  1. Article ; Online: Introduction to XIII Updating Course of Antimicrobials and Infectious Diseases.

    Candel, F J

    Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia

    2023  Volume 36 Suppl 1, Page(s) 1

    MeSH term(s) Humans ; Communicable Diseases/drug therapy ; Anti-Infective Agents/therapeutic use
    Chemical Substances Anti-Infective Agents
    Language English
    Publishing date 2023-11-24
    Publishing country Spain
    Document type Journal Article ; Review
    ZDB-ID 1018135-0
    ISSN 1988-9518 ; 0214-3429
    ISSN (online) 1988-9518
    ISSN 0214-3429
    DOI 10.37201/req/s01.00.2023
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2833: Show issues Location:
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  2. Article ; Online: Introduction to XII Updating Course of Antimicrobials and Infectious Diseases.

    Candel, F J

    Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia

    2022  Volume 35 Suppl 3, Page(s) 1

    MeSH term(s) Humans ; Communicable Diseases/drug therapy ; Anti-Infective Agents/therapeutic use
    Chemical Substances Anti-Infective Agents
    Language English
    Publishing date 2022-10-24
    Publishing country Spain
    Document type Journal Article ; Review
    ZDB-ID 1018135-0
    ISSN 1988-9518 ; 0214-3429
    ISSN (online) 1988-9518
    ISSN 0214-3429
    DOI 10.37201/req/s03.00.2022
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2833: Show issues Location:
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  3. Article ; Online: Introduction to XI Updating Course of Antimicrobials and Infectious Diseases.

    Candel, F J

    Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia

    2021  Volume 34 Suppl 1, Page(s) 1

    MeSH term(s) Anti-Infective Agents/therapeutic use ; Communicable Diseases/drug therapy ; Humans
    Chemical Substances Anti-Infective Agents
    Language English
    Publishing date 2021-09-30
    Publishing country Spain
    Document type Journal Article ; Review
    ZDB-ID 1018135-0
    ISSN 1988-9518 ; 0214-3429
    ISSN (online) 1988-9518
    ISSN 0214-3429
    DOI 10.37201/req/s01.00.2021
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2833: Show issues Location:
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  4. Article ; Online: Nosocomial pneumonia: Current etiology and impact on antimicrobial therapy.

    Gamazo, J J / Candel, F J / González Del Castillo, J

    Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia

    2023  Volume 36 Suppl 1, Page(s) 9–14

    Abstract: Nosocomial pneumonia is an infection with high clinical impact and high morbimortality in which Pseudomonas aeruginosa plays a priority role, especially in the critically ill patient. Conventional antipseudomonal treatments, historically considered as ... ...

    Abstract Nosocomial pneumonia is an infection with high clinical impact and high morbimortality in which Pseudomonas aeruginosa plays a priority role, especially in the critically ill patient. Conventional antipseudomonal treatments, historically considered as standard, are currently facing important challenges due to the increase of antimicrobial resistance. In recent years, new antimicrobials have been developed with attractive sensitivity profiles and remarkable efficacy in clinical scenarios of nosocomial pneumonia including bacteremia, mechanical ventilation, infections with multidrug-resistant organisms or situations of therapeutic failure. This new evidence underscores the need to update current clinical guidelines for the antimicrobial treatment of nosocomial pneumonia, especially in the most critically ill patients.
    MeSH term(s) Humans ; Anti-Bacterial Agents/therapeutic use ; Cross Infection/drug therapy ; Cross Infection/etiology ; Critical Illness ; Pseudomonas Infections/drug therapy ; Pseudomonas Infections/complications ; Healthcare-Associated Pneumonia/drug therapy ; Anti-Infective Agents/therapeutic use ; Pseudomonas aeruginosa
    Chemical Substances Anti-Bacterial Agents ; Anti-Infective Agents
    Language English
    Publishing date 2023-11-24
    Publishing country Spain
    Document type Journal Article ; Review
    ZDB-ID 1018135-0
    ISSN 1988-9518 ; 0214-3429
    ISSN (online) 1988-9518
    ISSN 0214-3429
    DOI 10.37201/req/s01.03.2023
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2833: Show issues Location:
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    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Risk of severe COVID in solid organ transplant recipient.

    Barreiro, P / Candel, F J / Carretero, M M / San Román, J

    Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia

    2023  Volume 36 Suppl 1, Page(s) 15–17

    Abstract: Despite the fact that COVID is today not a life-threat for the general population, recipients of solid organ transplantation should be viewed as a high risk group for severe COVID. Repetitive doses of SARS-CoV-2 vaccine still fail to protect SOT ... ...

    Abstract Despite the fact that COVID is today not a life-threat for the general population, recipients of solid organ transplantation should be viewed as a high risk group for severe COVID. Repetitive doses of SARS-CoV-2 vaccine still fail to protect SOT recipients from infection, disease or even death caused by COVID. A more frequent need for medical care may initially place these patients at greater chances of SARS-CoV-2 infection. Immunosuppression after engrafting and underlying medical conditions that led to the practice of SOT contribute to more risk of severe infection. Immunosuppression also blunts the intensity of humoral and cellular responses after vaccination, even when several booster doses have been administered. Still, vaccination is the best strategy to prevent a fatal outcome in case of SARS-CoV-2 infection, with a particular reduction in mortality. SOT recipients should be considered a high-risk population that need yearly SARS-CoV-2 vaccination.
    MeSH term(s) Humans ; COVID-19 ; COVID-19 Vaccines ; SARS-CoV-2 ; Transplant Recipients ; Organ Transplantation/adverse effects
    Chemical Substances COVID-19 Vaccines
    Language English
    Publishing date 2023-11-24
    Publishing country Spain
    Document type Journal Article ; Review
    ZDB-ID 1018135-0
    ISSN 1988-9518 ; 0214-3429
    ISSN (online) 1988-9518
    ISSN 0214-3429
    DOI 10.37201/req/s01.04.2023
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2833: Show issues Location:
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    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Candent issues in pneumonia. Reflections from the Fifth Annual Meeting of Spanish Experts 2023.

    Rodríguez-Leal, C M / González-Corralejo, C / Candel, F J / Salavert, M

    Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia

    2024  

    Abstract: Pneumonia is a multifaceted illness with a wide range of clinical manifestations, degree of severity and multiple potential causing microorganisms. Despite the intensive research of recent decades, community-acquired pneumonia remains the third-highest ... ...

    Abstract Pneumonia is a multifaceted illness with a wide range of clinical manifestations, degree of severity and multiple potential causing microorganisms. Despite the intensive research of recent decades, community-acquired pneumonia remains the third-highest cause of mortality in developed countries and the first due to infections; and hospital-acquired pneumonia is the main cause of death from nosocomial infection in critically ill patients. Guidelines for management of this disease are available world wide, but there are questions which generate controversy, and the latest advances make it difficult to stay them up to date. A multidisciplinary approach can overcome these limitations and can also aid to improve clinical results. Spanish medical societies involved in diagnosis and treatment of pneumonia have made a collaborative effort to actualize and integrate last expertise about this infection. The aim of this paper is to reflect this knowledge, communicated in Fifth Pneumonia Day in Spain. It reviews the most important questions about this disorder, such as microbiological diagnosis, advances in antibiotic and sequential therapy, management of beta-lactam allergic patient, preventive measures, management of unusual or multi-resistant microorganisms and adjuvant or advanced therapies in Intensive Care Unit.
    Language English
    Publishing date 2024-03-04
    Publishing country Spain
    Document type Journal Article ; Review
    ZDB-ID 1018135-0
    ISSN 1988-9518 ; 0214-3429
    ISSN (online) 1988-9518
    ISSN 0214-3429
    DOI 10.37201/req/018.2024
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2833: Show issues Location:
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  7. Article ; Online: Governance principles for accelerating food systems transformation in the European Union.

    Fesenfeld, Lukas Paul / Candel, Jeroen / Gaupp, Franziska

    Nature food

    2023  Volume 4, Issue 10, Page(s) 826–829

    Language English
    Publishing date 2023-09-26
    Publishing country England
    Document type Journal Article
    ISSN 2662-1355
    ISSN (online) 2662-1355
    DOI 10.1038/s43016-023-00850-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Introduction to Third Pneumonia National Meeting (November 12th, 2021).

    Candel, F J / Menéndez, R / Sancho, S

    Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia

    2022  Volume 35 Suppl 1, Page(s) 1

    MeSH term(s) Humans ; Pneumonia/drug therapy
    Language English
    Publishing date 2022-04-22
    Publishing country Spain
    Document type Journal Article ; Review
    ZDB-ID 1018135-0
    ISSN 1988-9518 ; 0214-3429
    ISSN (online) 1988-9518
    ISSN 0214-3429
    DOI 10.37201/req/s01.00.2022
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    Zs.A 2833: Show issues Location:
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  9. Article ; Online: Value of syndromic panels in the management of severe community-acquired pneumonia.

    Burillo, A / Candel, F J / Canut-Blasco, A

    Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia

    2022  Volume 35 Suppl 1, Page(s) 15–20

    Abstract: Community-acquired pneumonia requiring hospital admission is a prevalent and potentially serious infection, especially in high-risk patients (e.g., those requiring ICU admission or immunocompromised). International guidelines recommend early aetiological ...

    Abstract Community-acquired pneumonia requiring hospital admission is a prevalent and potentially serious infection, especially in high-risk patients (e.g., those requiring ICU admission or immunocompromised). International guidelines recommend early aetiological diagnosis to improve prognosis and reduce mortality. Syndromic panels that detect causative pathogens by molecular methods are here to stay. They are highly sensitive and specific for detecting the targets included in the test. A growing number of studies measuring their clinical impact have observed increased treatment appropriateness and decreased turnaround time to aetiological diagnosis, need for admission, length of hospital stay, days of isolation, adverse effects of medication and hospital costs. Its use is recommended a) per a pre-established protocol on making the diagnosis and managing the patient, b) together with an antimicrobial stewardship programme involving both the Microbiology Service and the clinicians responsible for the patient, and c) the final evaluation of the whole process. However, we recall that microbiological diagnosis with traditional methods remains mandatory due to the possibility that the aetiological agent is not included among the molecular targets and to determine the antimicrobial susceptibility of the pathogens detected.
    MeSH term(s) Community-Acquired Infections/diagnosis ; Community-Acquired Infections/drug therapy ; Community-Acquired Infections/microbiology ; Hospital Costs ; Hospitalization ; Humans ; Length of Stay ; Pneumonia/diagnosis ; Pneumonia/drug therapy
    Language English
    Publishing date 2022-04-22
    Publishing country Spain
    Document type Journal Article ; Review
    ZDB-ID 1018135-0
    ISSN 1988-9518 ; 0214-3429
    ISSN (online) 1988-9518
    ISSN 0214-3429
    DOI 10.37201/req/s01.03.2022
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Therapeutic strategy in the transplanted patient.

    Núñez-Orantos, M J / Julián-Jiménez, A / Candel, F J / González Del Castillo, J

    Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia

    2023  Volume 36 Suppl 1, Page(s) 18–21

    Abstract: The SARS-CoV-2 infection prognosis has dramatically changed as a result of population vaccination and the surge of omicron. However, there are still specific populations at risk of progression to severe diseases that require hospitalization or even at ... ...

    Abstract The SARS-CoV-2 infection prognosis has dramatically changed as a result of population vaccination and the surge of omicron. However, there are still specific populations at risk of progression to severe diseases that require hospitalization or even at risk of death. The kidney transplant population is one of them. Consequently, when compatible symptoms appear, an early diagnosis should be sought in order to start specific antiviral treatment as soon as possible to avoid clinical deterioration of the patient. Antivirals have shown, in transplant patients, a decrease in the rate of hospitalization and death, especially with their early administration.
    MeSH term(s) Humans ; Kidney Transplantation ; COVID-19 ; Hospitalization ; Vaccination
    Language English
    Publishing date 2023-11-24
    Publishing country Spain
    Document type Journal Article ; Review
    ZDB-ID 1018135-0
    ISSN 1988-9518 ; 0214-3429
    ISSN (online) 1988-9518
    ISSN 0214-3429
    DOI 10.37201/req/s01.05.2023
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