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  1. Article ; Online: Injudicious use of cranio-spinal imaging in Guillain-Barré syndrome in a low resource country.

    Hassan, Muhammad / Badshah, Mazhar / Iqbal, Mansoor

    Current journal of neurology

    2024  Volume 22, Issue 4, Page(s) 261–264

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2024-02-15
    Publishing country Iran
    Document type Journal Article
    ISSN 2717-011X
    ISSN (online) 2717-011X
    DOI 10.18502/cjn.v22i4.14532
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  2. Article ; Online: Letter to editor: Prophylactic use of statins in HIV patients: Better be safe than sorry.

    Shafiq, Muhammad Hamza / Farooq, Fatima / Mansoor, Misha / Ahmad, Muhammad Hassan

    Irish journal of medical science

    2024  

    Language English
    Publishing date 2024-04-30
    Publishing country Ireland
    Document type Letter
    ZDB-ID 390895-1
    ISSN 1863-4362 ; 0021-1265
    ISSN (online) 1863-4362
    ISSN 0021-1265
    DOI 10.1007/s11845-024-03696-4
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    Zs.B 323: Show issues Location:
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  3. Article: Pharmacokinetics of Midazolam in preterm neonates with an insight in brain Tissue: A PBPK approach.

    Mansoor, Najia / Ahmed, Mansoor / Czejka, Martin / Sharib, Syed / Hassan, Sohail / Hassan, Amir

    Pakistan journal of pharmaceutical sciences

    2022  Volume 35, Issue 5, Page(s) 1459–1465

    Abstract: Physiological maturity is a gradual process taking place throughout infancy and childhood. Though for years anatomical growth has been the basis for dose calculation in pediatric population, physiological immaturity can-not be overlooked especially in ... ...

    Abstract Physiological maturity is a gradual process taking place throughout infancy and childhood. Though for years anatomical growth has been the basis for dose calculation in pediatric population, physiological immaturity can-not be overlooked especially in neonates. The potential difference in physiology can significantly affect the outcomes of treatment and may result in under dosing or over-dosage. For many ethical and logistic constrains, carrying out pharmacokinetic studies of pharmacological agents in neonatal population remains a challenging task and such data is therefore, insufficient. This work presents Physiologically Based Pharmacokinetic modeling approach to predict the disposition of IV Midazolam in preterm neonates of different gestational ages, validated by the experimental studies. Furthermore, midazolam concentration in brain tissue of these neonates- the major site of its action- has been noted. The predicted and observed plasma pharmacokinetic parameters are comparable. This article demonstrates the usefulness of in-silico approach for finding out the PK parameters in neonates which may aid in deciding the frequency of drug administration in this population.
    MeSH term(s) Child ; Humans ; Infant, Newborn ; Midazolam ; Brain ; Gestational Age ; Plasma
    Chemical Substances Midazolam (R60L0SM5BC)
    Language English
    Publishing date 2022-12-01
    Publishing country Pakistan
    Document type Journal Article
    ZDB-ID 885131-1
    ISSN 1011-601X
    ISSN 1011-601X
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  4. Book ; Online: The Impact of Preference Agreement in Reinforcement Learning from Human Feedback

    Gooding, Sian / Mansoor, Hassan

    A Case Study in Summarization

    2023  

    Abstract: Reinforcement Learning from Human Feedback (RLHF) can be used to capture complex and nuanced properties of text generation quality. As a result, the task of text summarization has been identified as a good candidate for this process. In this paper, we ... ...

    Abstract Reinforcement Learning from Human Feedback (RLHF) can be used to capture complex and nuanced properties of text generation quality. As a result, the task of text summarization has been identified as a good candidate for this process. In this paper, we explore how preference agreement impacts the efficacy of RLHF for summarization. We show that sampling human preferences to include a range of annotator agreement results in (1) higher accuracy reward models and (2) alters the characteristics of quality captured. We additionally show improvements in downstream generation when using a reward model trained with a range of preference agreements. Our contributions have implications for the design of synthetic datasets as well as the importance of considering quality differentials in comparison-based data.
    Keywords Computer Science - Computation and Language ; Computer Science - Artificial Intelligence ; Computer Science - Human-Computer Interaction
    Publishing date 2023-11-02
    Publishing country us
    Document type Book ; Online
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  5. Article ; Online: Novel microbial synthesis of titania nanoparticles using probiotic Bacillus coagulans and its role in enhancing the microhardness of glass ionomer restorative materials.

    Mansoor, Afsheen / Mansoor, Emaan / Mehmood, Mazhar / Hassan, Syed Mujtaba Ul / Shah, Atta Ullah / Asjid, Uzma / Ishtiaq, Muhammad / Jamal, Asif / Rai, Akhilesh / Palma, Paulo J

    Odontology

    2024  

    Abstract: Dental caries is a commonly occurring non-communicable disease throughout the world that might compromise the quality of any individual's life. Glass ionomer cements (GIC) are the most acceptable restorative materials due to their ease of manipulation, ... ...

    Abstract Dental caries is a commonly occurring non-communicable disease throughout the world that might compromise the quality of any individual's life. Glass ionomer cements (GIC) are the most acceptable restorative materials due to their ease of manipulation, minimal tooth loss and least invasive strategy; however, they lack mechanical stability that has become a point of concern. Nanoparticles (NPs) are an outstanding option for modifying and enhancing the properties of dental materials. The focus of this study was to prepare novel, biocompatible titania dioxide (TiO
    Language English
    Publishing date 2024-03-30
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 2092085-4
    ISSN 1618-1255 ; 1618-1247
    ISSN (online) 1618-1255
    ISSN 1618-1247
    DOI 10.1007/s10266-024-00921-5
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  6. Article ; Online: A new deep learning-based technique for rice pest detection using remote sensing.

    Hassan, Syeda Iqra / Alam, Muhammad Mansoor / Illahi, Usman / Mohd Suud, Mazliham

    PeerJ. Computer science

    2023  Volume 9, Page(s) e1167

    Abstract: Background: Agriculture plays a vital role in the country's economy and human society. Rice production is mainly focused on financial improvements as it is demanding worldwide. Protecting the rice field from pests during seedling and after production is ...

    Abstract Background: Agriculture plays a vital role in the country's economy and human society. Rice production is mainly focused on financial improvements as it is demanding worldwide. Protecting the rice field from pests during seedling and after production is becoming a challenging research problem. Identifying the pest at the right time is crucial so that the measures to prevent rice crops from pests can be taken by considering its stage. In this article, a new deep learning-based pest detection model is proposed. The proposed system can detect two types of rice pests (stem borer and Hispa) using an unmanned aerial vehicle (UAV).
    Methodology: The image is captured in real time by a camera mounted on the UAV and then processed by filtering, labeling, and segmentation-based technique of color thresholding to convert the image into greyscale for extracting the region of interest. This article provides a rice pests dataset and a comparative analysis of existing pre-trained models. The proposed approach YO-CNN recommended in this study considers the results of the previous model because a smaller network was regarded to be better than a bigger one. Using additional layers has the advantage of preventing memorization, and it provides more precise results than existing techniques.
    Results: The main contribution of the research is implementing a new modified deep learning model named Yolo-convolution neural network (YO-CNN) to obtain a precise output of up to 0.980 accuracies. It can be used to reduce rice wastage during production by monitoring the pests regularly. This technique can be used further for target spraying that saves applicators (fertilizer water and pesticide) and reduces the adverse effect of improper use of applicators on the environment and human beings.
    Language English
    Publishing date 2023-03-06
    Publishing country United States
    Document type Journal Article
    ISSN 2376-5992
    ISSN (online) 2376-5992
    DOI 10.7717/peerj-cs.1167
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  7. Article: LUSPATERCEPT - A better strategy for thalassemia?

    Patel, Mustafa Saleem / Raza, Imran Mansoor / Hassan, Syeda Zuhaa

    JPMA. The Journal of the Pakistan Medical Association

    2021  Volume 71, Issue 8, Page(s) 2107

    MeSH term(s) Activin Receptors, Type II ; Humans ; Immunoglobulin Fc Fragments ; Recombinant Fusion Proteins ; Thalassemia/drug therapy ; beta-Thalassemia
    Chemical Substances Immunoglobulin Fc Fragments ; Recombinant Fusion Proteins ; luspatercept (AQK7UBA1LS) ; Activin Receptors, Type II (EC 2.7.11.30)
    Language English
    Publishing date 2021-08-21
    Publishing country Pakistan
    Document type Journal Article
    ZDB-ID 603873-6
    ISSN 0030-9982
    ISSN 0030-9982
    DOI 10.47391/JPMA.773
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  8. Article ; Online: Identifying and Prioritizing the Factors Affecting Creativity and Innovation in Public Libraries

    Mohammad Hassan Azimi / mansoor koohi rostami / Fatemeh hosseinzade

    تحقیقات اطلاع‌رسانی و کتابخانه‌های عمومی, Vol 27, Iss 4, Pp 707-

    2022  Volume 738

    Abstract: Purpose: To identify and prioritize the factors affecting innovation and creativity in public libraries from the perspective of public librarians in Khuzestan province. Method: The present research is an exploratory and mixed study in terms of purpose. ... ...

    Abstract Purpose: To identify and prioritize the factors affecting innovation and creativity in public libraries from the perspective of public librarians in Khuzestan province. Method: The present research is an exploratory and mixed study in terms of purpose. The statistical population in the qualitative section included 22 university professors who were selected by purposive sampling. The research population in the quantitative section included all librarians of public libraries in Khuzestan province. The data collection tool was a questionnaire. Data were analyzed using descriptive statistics including frequency and frequency percentage and inferential statistics tests including t-test, structural equation modeling, heuristic factor analysis and confirmatory factor analysis using SPSS and Wimos software. Findings: Qualitative section of research involved the identification of 50 components affecting creativity and innovation in public libraries in Khuzestan province. Based on the findings of the quantitative section, the factors affecting creativity and innovation in public libraries from the perspective of librarians of public libraries in Khuzestan province can be classified into 8 general factors, which are: organizational culture, individual factors and personality traits, organizational structure, organizational strategy, organizational management and leadership, organizational climate, organizational motivation and reward, and organizational resources. Originality/value: In order to develop creativity in all organizational elements, there must be an atmosphere in which employees feel free in the way they perform their duties and have control over their work, and their authority and choices should be supported in achieving goals, and the control over individuals’ work should be reduced to a minimum. Motivation and reward, as an effective factor in fostering creativity and innovation, is the driving force of employees’ creativity. Motivations such as welfare and financial issues, self-preservation, curiosity, ...
    Keywords creativity ; innovation ; librarian ; public libraries ; Bibliography. Library science. Information resources ; Z ; Information technology ; T58.5-58.64
    Subject code 306
    Language Persian
    Publishing date 2022-03-01T00:00:00Z
    Publisher Iran Public Libraries Foundation
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article: Indoxacarb poisoning presenting as methemoglobinemia: A case report.

    Mohammed, Abdelhakim Osman Hassan / Saeed, Malik Muhammed Akbar / Ahmad, Akhwand Shakeel / Abdulla, Mansoor C

    International journal of critical illness and injury science

    2024  Volume 14, Issue 1, Page(s) 59–61

    Abstract: A 34-year-old Sri Lankan man presented with multiple episodes of vomiting following accidental ingestion of 100 ml of indoxacarb (Avaunt). He had a significant saturation gap (discrepancy between oxygen saturation [98%] in blood gas analysis and ... ...

    Abstract A 34-year-old Sri Lankan man presented with multiple episodes of vomiting following accidental ingestion of 100 ml of indoxacarb (Avaunt). He had a significant saturation gap (discrepancy between oxygen saturation [98%] in blood gas analysis and saturation on pulse oximetry [70%] in finger pulse oximetry), the color of the blood was muddy brown, and the methemoglobin level (60%) was high in the blood gas analysis. A diagnosis of methemoglobinemia secondary to indoxacarb poisoning was made, and he was treated with methylene blue with a favorable outcome. Methemoglobinemia secondary to indoxacarb poisoning is extremely rare, and clinicians should be aware of this important complication. Methemoglobinemia secondary to indoxacarb poisoning has a favorable outcome if recognized and treated promptly.
    Language English
    Publishing date 2024-03-27
    Publishing country India
    Document type Case Reports
    ZDB-ID 2638865-0
    ISSN 2231-5004 ; 2229-5151
    ISSN (online) 2231-5004
    ISSN 2229-5151
    DOI 10.4103/ijciis.ijciis_37_23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Detection and genomic characterization of Klebsiella pneumoniae and Escherichia coli harboring tet(X4) in black kites (Milvus migrans) in Pakistan.

    Mansoor, Muhammad Hassan / Lu, Xiaoyu / Woksepp, Hanna / Sattar, Amna / Humak, Farwa / Ali, Jabir / Li, Ruichao / Bonnedahl, Jonas / Mohsin, Mashkoor

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 9054

    Abstract: The emergence of plasmid-mediated tigecycline resistance gene tet(X4) among clinically relevant bacteria has promoted significant concerns, as tigecycline is considered a last-resort drug against serious infections caused by multidrug-resistant bacteria. ...

    Abstract The emergence of plasmid-mediated tigecycline resistance gene tet(X4) among clinically relevant bacteria has promoted significant concerns, as tigecycline is considered a last-resort drug against serious infections caused by multidrug-resistant bacteria. We herein focused on the isolation and molecular characterization of tet(X4)-positive Klebsiella pneumoniae (K. pneumoniae) and Escherichia coli (E. coli) in wild bird populations with anthropogenic interaction in Faisalabad, Pakistan. A total of 150 birds including black kites (Milvus migrans) and house crows (Corvus splendens) were screened for the presence of tigecycline resistance K. pneumoniae and E. coli. We found two K. pneumoniae and one E. coli isolate carrying tet(X4) originating from black kites. A combination of short- and long-read sequencing strategies showed that tet(X4) was located on a broad host range IncFII plasmid family in K. pneumoniae isolates whereas on an IncFII-IncFIB hybrid plasmid in E. coli. We also found an integrative and conjugative element ICEKp2 in K. pneumoniae isolate KP8336. We demonstrate the first description of tet(X4) gene in the WHO critical-priority pathogen K. pneumoniae among wild birds. The convergence of tet(X4) and virulence associated ICEKp2 in a wild bird with known anthropogenic contact should be further investigated to evaluate the potential epidemiological implications. The potential risk of global transmission of tet(X4)-positive K. pneumoniae and E. coli warrant comprehensive evaluation and emphasizes the need for effective mitigation strategies to reduce anthropogenic-driven dissemination of AMR in the environment.
    MeSH term(s) Animals ; Tigecycline/pharmacology ; Escherichia coli ; Anti-Bacterial Agents/pharmacology ; Klebsiella pneumoniae ; Pakistan ; Drug Resistance, Bacterial/genetics ; Birds/genetics ; Plasmids/genetics ; Genomics ; Microbial Sensitivity Tests
    Chemical Substances Tigecycline (70JE2N95KR) ; Anti-Bacterial Agents
    Language English
    Publishing date 2024-04-20
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-59201-5
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