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Article ; Online: Clostridium difficile associated disease.

Hassoun, Ali

2018 Volume 363, Page(s) k4369

MeSH term(s)	Abdominal Pain/diagnosis ; Anti-Bacterial Agents/therapeutic use ; Clostridium Infections/diagnosis ; Clostridium Infections/microbiology ; Clostridium Infections/therapy ; Clostridium difficile ; Diarrhea/diagnosis ; Digestive System Surgical Procedures ; Fecal Microbiota Transplantation ; Humans ; Practice Guidelines as Topic ; Recurrence ; Risk Factors
Chemical Substances	Anti-Bacterial Agents
Language	English
Publishing date	2018-10-29
Publishing country	England
Document type	Journal Article
ZDB-ID	1362901-3
ISSN	1756-1833 ; 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
ISSN (online)	1756-1833
ISSN	0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
DOI	10.1136/bmj.k4369
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: A Case of Disseminated Histoplasmosis Presenting in a 65-Year-Old Male Without Apparent Immunodeficiency Successfully Treated With Isavuconazole.

Boney, Colton P / Hassoun, Ali / Viswanathan, Sandhya / Shrestha, Rabi

Cureus

2024 Volume 16, Issue 2, Page(s) e53495

Abstract: Histoplasma ... ...

Abstract	Histoplasma capsulatum
Language	English
Publishing date	2024-02-03
Publishing country	United States
Document type	Case Reports
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.53495
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: A Rare Complication of Leptospirosis: Weil's Disease Diagnosed in the United States.

Rathi, Hinal / Patel, Aesha / Beblawy, Rafik / Hassoun, Ali

Cureus

2023 Volume 15, Issue 8, Page(s) e43620

Abstract: Leptospirosis is mostly found in tropical regions such as Latin America and Southeast Asia. Here we present a case of leptospirosis in the United States in a 43-year-old African American male who had complications such as sepsis, acute renal failure, ... ...

Abstract	Leptospirosis is mostly found in tropical regions such as Latin America and Southeast Asia. Here we present a case of leptospirosis in the United States in a 43-year-old African American male who had complications such as sepsis, acute renal failure, hyperbilirubinemia, and transaminitis. Through this case report, we want to highlight the rare occurrence of this infection in the United States. It should be considered high in the list of differential diagnoses for patients traveling to underdeveloped countries and participating in adventure sports. Early recognition and treatment of leptospirosis are essential in decreasing life-threatening complications.
Language	English
Publishing date	2023-08-17
Publishing country	United States
Document type	Case Reports
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.43620
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: The Bay Area Muslim mental health community advisory board: evaluation of a community based participatory approach.

Ali, S S / Mahoui, I / Hassoun, R / Mojaddidi, H / Awaad, R

Epidemiology and psychiatric sciences

2023 Volume 32, Page(s) e7

Abstract: Aims: The aim of this paper is to present a novel case for the formation, operation and evaluation of a community advisory aboard comprised of Muslims residing in the San Francisco Bay Area, California that utilised a community based participatory ... ...

Abstract	Aims: The aim of this paper is to present a novel case for the formation, operation and evaluation of a community advisory aboard comprised of Muslims residing in the San Francisco Bay Area, California that utilised a community based participatory approach to address local Muslim mental health needs. The CAB was recruited in partnership with the Muslim Community Association (MCA), one of the largest Islamic centres in the San Franscisco Bay Area. In addition to describing the development of the CAB, the authors present the findings of the evaluation and synthesis of best processes based on CAB members' feedback. Methods: To evaluate the perceived community advisory board members' perceptions of their roles and elicit feedback on how to enhance the relationship between the university team and the CAB, an evaluation was conducted by an independent team who was not part of the research process. Data was collected using anonymous individual surveys and small group open discussions that were conducted over three evaluation meetings. The evaluation utilised mixed method data collection strategies using questions from Schulz Results: Results of the evaluation within the sphere of CAB operation indicated that CAB members found the greatest satisfaction from their contributions through direct participation in the research activities that were conducted by the university-CAB team. The collective responses indicated that most CAB members were satisfied with trust built between the university-CAB team and the diversity represented in the members of the board. However, given that the Bay Area is home to a very diverse Muslim community, challenges in recruiting representatives that account for all possible self-identifying groups was reported by the CAB with recommendations to recruit religious leaders. Recommendations also included eliciting funds for potential financial compensation for CAB members. Conclusions: The Stanford-San Francisco Bay Area CAB demonstrated that empowering community members through direct participation, creating channels and safe spaces for feedback help create community rooted research that carry the true voices of marginalised communities and reflects their evolving needs.
MeSH term(s)	Humans ; Islam ; Mental Health ; Community-Based Participatory Research/methods ; Community Participation ; Cooperative Behavior
Language	English
Publishing date	2023-01-31
Publishing country	England
Document type	Journal Article
ZDB-ID	2607964-1
ISSN	2045-7979 ; 2045-7960
ISSN (online)	2045-7979
ISSN	2045-7960
DOI	10.1017/S2045796022000786
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Article ; Online: Can we reduce contact precautions days for methicillin-resistant Staphylococcus aureus and vancomycin resistant Enterococcus infected patients?

Thottacherry, Elizabeth Dilip / Hassoun, Ali

Journal of infection and public health

2020 Volume 13, Issue 8, Page(s) 1118–1122

Abstract: Background: Patients with MRSA (methicillin-resistant Staphylococcus aureus) and VRE (vancomycin resistant Enterococcus) are placed under contact precautions according to the Center of Disease Control protocol. Contact precautions however increases ... ...

Abstract	Background: Patients with MRSA (methicillin-resistant Staphylococcus aureus) and VRE (vancomycin resistant Enterococcus) are placed under contact precautions according to the Center of Disease Control protocol. Contact precautions however increases patient isolation from Health Care Workers, increase overall hospital costs and may increase depression and anxiety. Our aim in this study was to observe the effects of shortening the number of days of contact precautions for patients infected with MRSA and VRE. Method: We observed patients as two cohorts (Pre-Pilot and Pilot) in one Medical Intensive Care Unit, one Surgical Intensive Care Unit & two medical floors during 2014-2015. In the Pre-pilot period contact precautions were kept throughout admission. In the Pilot period contact precautions were initially placed followed by universal gloving. Comparisons were made for MRSA and VRE infection rates. Total costs were estimated assuming the average cost of 1 gown was $26 per patient per day. Results: Mean isolation days were reduced from 11.9 days to 6.8 days for MRSA and 12.8 days to 8.4 days for VRE. There were 86 MRSA infections in the Pre-Pilot period and 73 MRSA infections during the Pilot period (p=0.052). Incidence of hospital acquired MRSA in the wards decreased from 15 to 7 cases and 6 to 2 cases in the Intensive Care Unit in both the Pilot and Pre-Pilot periods respectively. Cost reduced by $2476 and $17,336 per month for VRE and MRSA patients. Number of readmissions also decreased by 39% for MRSA and 50% for VRE. Conclusions: A reduction in contact precautions has reduced patient costs without affecting the rate of MRSA and VRE infection within a one-year period.
MeSH term(s)	Cross Infection/epidemiology ; Cross Infection/prevention & control ; Gram-Positive Bacterial Infections/epidemiology ; Gram-Positive Bacterial Infections/prevention & control ; Humans ; Infection Control/methods ; Methicillin-Resistant Staphylococcus aureus ; Patient Isolation/statistics & numerical data ; Staphylococcal Infections/epidemiology ; Staphylococcal Infections/prevention & control ; Vancomycin-Resistant Enterococci
Language	English
Publishing date	2020-04-23
Publishing country	England
Document type	Journal Article
ISSN	1876-035X
ISSN (online)	1876-035X
DOI	10.1016/j.jiph.2020.04.003
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Myocarditis presentation following COVID-19 virus infection versus COVID-19 vaccination.

Yendrapalli, Usha / Hassoun, Ali / Zalamea, Roderick M / Hritani, Abdulwahab

American journal of cardiovascular disease

2022 Volume 12, Issue 5, Page(s) 272–277

Abstract: Coronavirus disease 2019 (COVID-19) vaccine-induced cardiac injury has recently emerged as a major public health concern around the globe. There are reported cases of COVID-19 vaccine-induced myocarditis, but they are generally extremely rare and mild. ... ...

Abstract	Coronavirus disease 2019 (COVID-19) vaccine-induced cardiac injury has recently emerged as a major public health concern around the globe. There are reported cases of COVID-19 vaccine-induced myocarditis, but they are generally extremely rare and mild. In contrast, COVID-19 infection can cause acute cardiac injury with poor prognosis and high mortality rates. Herein, we describe the difference in patients' presentation by comparing two cases of myocarditis. One after contracting COVID-19 virus infection with a severe clinical course, and the other patient developed myocarditis post-COVID-19 vaccine.
Language	English
Publishing date	2022-10-15
Publishing country	United States
Document type	Journal Article
ZDB-ID	2616844-3
ISSN	2160-200X
ISSN	2160-200X
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Esophageal cancer: a twenty-four-year experience at a tertiary care center with an evaluation of the prognostic significance of the neutrophil-lymphocyte ratio.

Mahmoud, Walaa / Hassoun, Lara / Kerbage, Anthony / Mukherji, Deborah / Shamseddine, Ali / Tamraz, Sally / Hakim, Ayman / Barada, Kassem

BMC gastroenterology

2024 Volume 24, Issue 1, Page(s) 27

Abstract: Background: A high neutrophil-lymphocyte ratio (NLR) may be associated with worse survival in esophageal cancer (EC). Our aims were to describe the demographic and clinical data of EC in a tertiary referral center in Lebanon and to determine the ... ...

Abstract	Background: A high neutrophil-lymphocyte ratio (NLR) may be associated with worse survival in esophageal cancer (EC). Our aims were to describe the demographic and clinical data of EC in a tertiary referral center in Lebanon and to determine the prognostic value of NLR. Methods: A retrospective cohort study based on chart review of patients diagnosed with EC was conducted at the American University of Beirut Medical Center (AUBMC). The demographic characteristics, clinical presentation and outcomes were described and compared between squamous cell carcinomas (ESCC) and adenocarcinomas (EAC). Data about esophageal cancer incidence were obtained from the National Cancer Registry, the Ministry of Public Health and GLOBOCAN 2020. Cox regression analysis was performed to determine whether the NLR is an independent predictor of survival, using variables based on clinical knowledge and previously established data. Results: 110 patients were diagnosed with EC, which was the least common among other gastrointestinal malignancies. Our follow up rates reached 86.4%. The median survival was 9 months (IQR 3-25.5.) and was comparable between ESCC (median of 7 months, IQR 2-25) and EAC (median of 9 months, IQR 3-26.3), p = 0.803. Advanced stage was associated with a worse prognosis (p = 0.037). The mean NLR(±SD) was 5.20 ± 6.8, with no significant difference between EAC and ESCC (4.5 ± 3.4 vs. 5.9 ± 9.2, p = 0.420) or between early or advanced stages (5.4 ± 8.1 vs. 4.7 ± 6.8, p = 0.732). The area under the curve for the NLR was 0.560 (95% CI: 0.374-0.746, p = 0.488). After adjusting for age, gender, TNM staging and grading, cox regression analysis showed that an increased NLR was a significant predictor of mortality, with an adjusted hazard ratio of 1.095 (p = 0.011). Conclusion: EC is quite uncommon in Lebanon despite a high prevalence of smoking and obesity. Advanced stage and high NLR were associated with a negative prognostic value.
MeSH term(s)	Humans ; Prognosis ; Tertiary Care Centers ; Neutrophils ; Retrospective Studies ; Esophageal Neoplasms ; Lymphocytes
Language	English
Publishing date	2024-01-09
Publishing country	England
Document type	Journal Article
ZDB-ID	2041351-8
ISSN	1471-230X ; 1471-230X
ISSN (online)	1471-230X
ISSN	1471-230X
DOI	10.1186/s12876-023-03115-5
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Efficacy and safety of commercialized fecal microbiota transplant for the treatment of recurrent Clostridioides difficile infection.

Yendrapalli, Usha / Edwards, Jonathan / Belk, Madeline / Steuber, Taylor / Hassoun, Ali

Infection, disease & health

2022 Volume 28, Issue 1, Page(s) 71–73

MeSH term(s)	Humans ; Fecal Microbiota Transplantation ; Clostridium Infections/therapy ; Feces
Language	English
Publishing date	2022-07-21
Publishing country	Netherlands
Document type	Letter
ZDB-ID	2902143-1
ISSN	2468-0869 ; 2468-0451
ISSN (online)	2468-0869
ISSN	2468-0451
DOI	10.1016/j.idh.2022.06.002
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Article ; Online: Knowledge, attitude and practices of insulin therapy among patients with type 2 diabetes: a cross-sectional study.

Almheiri, Ayesha / Binjab, Eman Ali / Albloushi, Maha Murad / Alshamsi, Mohamed Taryam / Khansaheb, Hamda Hassan / Zidan, Marwan / Hassoun, Ahmed Abdul Karim

BMJ open

2024 Volume 14, Issue 3, Page(s) e079693

Abstract: Objectives: This study aimed to assess the knowledge, attitude and practices of patients with type 2 diabetes on insulin regarding insulin therapy.: Design: A cross-sectional study.: Setting: This study was conducted at the Dubai Diabetes Center ... ...

Abstract	Objectives: This study aimed to assess the knowledge, attitude and practices of patients with type 2 diabetes on insulin regarding insulin therapy. Design: A cross-sectional study. Setting: This study was conducted at the Dubai Diabetes Center from 1 December 2018 to 1 March 2020. Participants: Face-to-face interviews were conducted for 350 participants with type 2 diabetes at the Dubai Diabetes Center. Interviews followed the structured format of a questionnaire designed to obtain demographic details and score participants on knowledge, attitude and practices. We included patients aged >18 years and receiving insulin therapy. Patients with type 1 diabetes, pregnant women with gestational diabetes, those aged <18 years or those with a history of dementia were excluded. Results: The median age of participants was 61 years (first quartile, 53 years; third quartile, 67 years); 35.7% were male individuals and 64.3% were female individuals. The median percentage scores for knowledge, attitude and practices were 62.5% (62.5%, 75%), 85.7% (71.4%, 100%) and 77.7% (66.6%, 88.8%), respectively. Highly educated participants had a high level of knowledge. Significant negative correlations were found between the percentage knowledge scores and participants' age and between the participants' percentage attitude scores and haemoglobin A1C levels; Spearman's correlations were -0.182 (p<0.001) and -0.14 (p=0.008), respectively. A significant positive Spearman's correlation of 0.123 (p=0.021) was found between the percentage knowledge and percentage practice scores. No correlations were found among knowledge levels, participants' haemoglobin A1c levels and duration of insulin use. Conclusion: Patients with type 2 diabetes receiving insulin therapy and attending the Dubai Diabetes Center had adequate knowledge, a positive attitude and correct practice regarding insulin therapy. However, knowledge of specific facts did not always translate into correct behaviours and practices.
MeSH term(s)	Pregnancy ; Humans ; Female ; Male ; Middle Aged ; Insulin/therapeutic use ; Diabetes Mellitus, Type 2/drug therapy ; Cross-Sectional Studies ; Glycated Hemoglobin ; Health Knowledge, Attitudes, Practice
Chemical Substances	Insulin ; Glycated Hemoglobin
Language	English
Publishing date	2024-03-05
Publishing country	England
Document type	Journal Article
ZDB-ID	2599832-8
ISSN	2044-6055 ; 2044-6055
ISSN (online)	2044-6055
ISSN	2044-6055
DOI	10.1136/bmjopen-2023-079693
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Tuberculous mycotic aneurysm of aortic arch: a case report emphasising on multidisciplinary management approach.

Velu, Dhivya / Ibrahim, Farrah / Hassoun, Ali

BMJ case reports

2021 Volume 14, Issue 2

Abstract: Although tuberculosis (TB) is a well-known infection worldwide, the disease involvement in blood vessels, mainly aorta, is quite rare. The objective of this case report is to address the importance of a multidisciplinary approach aiming at successful ... ...

Abstract	Although tuberculosis (TB) is a well-known infection worldwide, the disease involvement in blood vessels, mainly aorta, is quite rare. The objective of this case report is to address the importance of a multidisciplinary approach aiming at successful treatment of tuberculosis, especially when presenting with mycotic aneurysm. We report a case of a 45-year-old woman with the history of sputum positive pulmonary TB, presenting with seizures and eventually found to have developed disseminated infection involving multiple organs, including the aorta. The patient was started on WHO-recommended anti-tubercular treatment but ended up requiring surgical intervention for the aneurysm. Although the main modality of treatment is the use of proper and adequate medical therapy, vascular dissemination in the form of mycotic aneurysm is difficult to be dealt singlehandedly due to their irreversible and multifactorial nature, with infection being the leading cause and their tendency to progress despite the primary infection being treated.
MeSH term(s)	Aneurysm, Infected/diagnostic imaging ; Aneurysm, Infected/surgery ; Aorta ; Aorta, Thoracic/diagnostic imaging ; Aorta, Thoracic/surgery ; Female ; Humans ; Middle Aged ; Tuberculosis
Language	English
Publishing date	2021-02-18
Publishing country	England
Document type	Case Reports ; Journal Article
ISSN	1757-790X
ISSN (online)	1757-790X
DOI	10.1136/bcr-2020-239309
Database	MEDical Literature Analysis and Retrieval System OnLINE

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