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  1. Article: Roundup® disrupts tissue architecture, attenuates Na

    Noor, Md Imran / Rahman, Md Saydur

    Comparative biochemistry and physiology. Toxicology & pharmacology : CBP

    2023  Volume 272, Page(s) 109710

    Abstract: Extensive agricultural activities to feed the growing population are one major driving force behind aquatic pollution. Different types of pesticides are used in farmlands to increase crop production and wash up into water bodies. Glyphosate-based ... ...

    Abstract Extensive agricultural activities to feed the growing population are one major driving force behind aquatic pollution. Different types of pesticides are used in farmlands to increase crop production and wash up into water bodies. Glyphosate-based herbicide Roundup® is one of the most used pesticides in the United States; however, its effects on teleost species are still poorly understood. This study focused on the effects of environmentally relevant concentrations of Roundup exposure (low- and high-dose: 0.5 and 5 μg/L for 2-week) on Na
    MeSH term(s) Animals ; Antioxidants/metabolism ; Goldfish/metabolism ; Gills/metabolism ; Sodium-Potassium-Exchanging ATPase/metabolism ; Superoxide Dismutase/metabolism ; Herbicides ; Apoptosis ; Sodium/metabolism ; Biomarkers/metabolism
    Chemical Substances Antioxidants ; Sodium-Potassium-Exchanging ATPase (EC 7.2.2.13) ; Superoxide Dismutase (EC 1.15.1.1) ; Herbicides ; Sodium (9NEZ333N27) ; Biomarkers
    Language English
    Publishing date 2023-07-31
    Publishing country United States
    Document type Journal Article
    ZDB-ID 189285-x
    ISSN 1532-0456 ; 0306-4492 ; 0742-8413
    ISSN 1532-0456 ; 0306-4492 ; 0742-8413
    DOI 10.1016/j.cbpc.2023.109710
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Exploring the Antarctic aminopeptidase P from

    Omar, Muhamad Nadzmi / Rahman, Raja Noor Zaliha Raja Abd / Noor, Noor Dina Muhd / Latip, Wahhida / Knight, Victor Feizal / Ali, Mohd Shukuri Mohamad

    Journal of biomolecular structure & dynamics

    2024  , Page(s) 1–13

    Abstract: Aminopeptidase P (APPro) is a crucial metalloaminopeptidase involved in amino acid cleavage from peptide N-termini, playing essential roles as versatile biocatalysts with applications ranging from pharmaceuticals to industrial processes. Despite ... ...

    Abstract Aminopeptidase P (APPro) is a crucial metalloaminopeptidase involved in amino acid cleavage from peptide N-termini, playing essential roles as versatile biocatalysts with applications ranging from pharmaceuticals to industrial processes. Despite acknowledging its potential for catalysis in lower temperatures, detailed molecular basis and biotechnological implications in cold environments are yet to be explored. Therefore, this research aims to investigate the molecular mechanisms underlying the cold-adapted characteristics of APPro from
    Language English
    Publishing date 2024-03-31
    Publishing country England
    Document type Journal Article
    ZDB-ID 49157-3
    ISSN 1538-0254 ; 0739-1102
    ISSN (online) 1538-0254
    ISSN 0739-1102
    DOI 10.1080/07391102.2024.2331093
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  3. Article: Conflict Of Interests Driven By Pharmaceutical Incentivisation: Risks To The Medical Fraternity In Pakistan.

    Noor, Muhammad Naveed / Shepherd, Afifah Rahman / Siddiqui, Amna Rehana

    JPMA. The Journal of the Pakistan Medical Association

    2023  Volume 73, Issue 11, Page(s) 2150–2151

    MeSH term(s) Humans ; Pakistan ; Conflict of Interest ; Pharmacy ; Drug Industry ; Pharmaceutical Preparations
    Chemical Substances Pharmaceutical Preparations
    Language English
    Publishing date 2023-11-28
    Publishing country Pakistan
    Document type Editorial
    ZDB-ID 603873-6
    ISSN 0030-9982
    ISSN 0030-9982
    DOI 10.47391/JPMA.23-91
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  4. Article: Correction: Patient-controlled analgesia morphine for the management of acute pain in the emergency department: a systematic review and meta-analysis.

    Oon, Muhammad Baihaqi / Hisamuddin, Nik Nik Ab Rahman / Noor, Norhayati Mohd / Yazid, Mohd Boniami

    International journal of emergency medicine

    2024  Volume 17, Issue 1, Page(s) 54

    Language English
    Publishing date 2024-04-10
    Publishing country England
    Document type Published Erratum
    ZDB-ID 2411462-5
    ISSN 1865-1380 ; 1865-1372
    ISSN (online) 1865-1380
    ISSN 1865-1372
    DOI 10.1186/s12245-024-00625-1
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  5. Article ; Online: Effects of alcohol concentration and temperature on the dynamics and stability of mutant Staphylococcal lipase.

    Ong, Shir Nee / Kamarudin, Nor Hafizah Ahmad / Shariff, Fairolniza Mohd / Noor, Noor Dina Muhd / Ali, Mohd Shukuri Mohamad / Rahman, Raja Noor Zaliha Raja Abd

    Journal of biomolecular structure & dynamics

    2023  , Page(s) 1–17

    Abstract: The stability and activity of lipase in organic media are important parameters in determining how quickly biocatalysis proceeds. This study aimed to examine the effects of two commonly used alcohols in industrial applications, methanol (MtOH) and ethanol ...

    Abstract The stability and activity of lipase in organic media are important parameters in determining how quickly biocatalysis proceeds. This study aimed to examine the effects of two commonly used alcohols in industrial applications, methanol (MtOH) and ethanol (EtOH) on the conformational stability and catalytic activity of G210C lipase, a laboratory-evolved mutant of
    Language English
    Publishing date 2023-11-15
    Publishing country England
    Document type Journal Article
    ZDB-ID 49157-3
    ISSN 1538-0254 ; 0739-1102
    ISSN (online) 1538-0254
    ISSN 0739-1102
    DOI 10.1080/07391102.2023.2282177
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  6. Article: Procedure of the overexpression, purification and crystallization of BLEG-1, a bifunctional and evolutionary divergent B3 metallo-β-lactamase, for structure-function studies.

    Au, Shaw Xian / Noor, Noor Dina Muhd / Matsumura, Hiroyoshi / Rahman, Raja Noor Zaliha Raja Abdul / Normi, Yahaya M

    MethodsX

    2022  Volume 9, Page(s) 101740

    Abstract: Metallo-β-lactamases (MBLs) are class B β-lactamases from the metallo-hydrolase-like MBL-fold superfamily which act on a broad range of β-lactam antibiotics, thus conferring antibiotics resistance to bacterial pathogens. The attempt to structurally ... ...

    Abstract Metallo-β-lactamases (MBLs) are class B β-lactamases from the metallo-hydrolase-like MBL-fold superfamily which act on a broad range of β-lactam antibiotics, thus conferring antibiotics resistance to bacterial pathogens. The attempt to structurally characterize BLEG-1, an evolutionary divergent B3 metallo-β-lactamase (MBL) with dual activity from
    Language English
    Publishing date 2022-05-27
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2830212-6
    ISSN 2215-0161
    ISSN 2215-0161
    DOI 10.1016/j.mex.2022.101740
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  7. Article ; Online: We need a universally endorsed definition of a pandemic for the Pandemic Accord to be effective.

    Shakfeh, Noor / Rahman, Fifa A / Bertram, Katri

    BMJ (Clinical research ed.)

    2023  Volume 382, Page(s) 1946

    MeSH term(s) Humans ; Pandemics/prevention & control
    Language English
    Publishing date 2023-08-23
    Publishing country England
    Document type Editorial
    ZDB-ID 1362901-3
    ISSN 1756-1833 ; 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    ISSN (online) 1756-1833
    ISSN 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    DOI 10.1136/bmj.p1946
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  8. Article ; Online: Retraction Note: Investigation of the mechanism of gamma irradiation effect on bovine bone.

    Rahman, Noor / Khan, Rafiullah / Hussain, Tanvir / Ahmed, Nabi

    Cell and tissue banking

    2023  

    Language English
    Publishing date 2023-08-24
    Publishing country Netherlands
    Document type Retraction of Publication
    ZDB-ID 2170897-6
    ISSN 1573-6814 ; 1389-9333
    ISSN (online) 1573-6814
    ISSN 1389-9333
    DOI 10.1007/s10561-023-10108-x
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  9. Article: Ficus deltoidea

    Abrahim, Noor Nazirahanie / Aminudin, Norhaniza / Abdul-Rahman, Puteri Shafinaz

    Food technology and biotechnology

    2023  Volume 61, Issue 2, Page(s) 191–201

    Abstract: Research background: Ficus deltoidea: Experimental approach: The leaves of three : Results and conclusions: Ficus deltoidea: Novelty and scientific contribution: F. ... ...

    Abstract Research background: Ficus deltoidea
    Experimental approach: The leaves of three
    Results and conclusions: Ficus deltoidea
    Novelty and scientific contribution: F. deltoidea
    Language English
    Publishing date 2023-07-05
    Publishing country Croatia
    Document type Journal Article
    ZDB-ID 1340467-2
    ISSN 1330-9862
    ISSN 1330-9862
    DOI 10.17113/ftb.61.02.23.7802
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    Z 7645: Show issues

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  10. Article ; Online: Expression and functional analysis of a recombinant aquaporin Z from Antarctic Pseudomonas sp. AMS3.

    Balakrishnan, S / Rahman, R N Z R A / Noor, N D M / Latip, W / Ali, M S M

    Proteins

    2024  

    Abstract: Aquaporin (AQP) is a water channel protein from the family of transmembrane proteins which facilitates the movement of water across the cell membrane. It is ubiquitous in nature, however the understanding of the water transport mechanism, especially for ... ...

    Abstract Aquaporin (AQP) is a water channel protein from the family of transmembrane proteins which facilitates the movement of water across the cell membrane. It is ubiquitous in nature, however the understanding of the water transport mechanism, especially for AQPs in microbes adapted to low temperatures, remains limited. AQP also has been recognized for its ability to be used for water filtration, but knowledge of the biochemical features necessary for its potential applications in industrial processes has been lacking. Therefore, this research was conducted to express, extract, solubilize, purify, and study the functional adaptations of the aquaporin Z family from Pseudomonas sp. AMS3 via molecular approaches. In this study, AqpZ1 AMS3 was successfully subcloned and expressed in E. coli BL21 (DE3) as a recombinant protein. The AqpZ1 AMS3 gene was expressed under optimized conditions and the best optimized condition for the AQP was in 0.5 mM IPTG incubated at 25°C for 20 h induction time. A zwitterionic mild detergent [(3-cholamidopropyl) dimethylammonio]-1-propanesulfonate was the suitable surfactant for the protein solubilization. The protein was then purified via affinity chromatography. Liposome and proteoliposome was reconstituted to determine the particle size using dynamic light scattering. This information obtained from this psychrophilic AQP identified provides new insights into the structural adaptation of this protein at low temperatures and could be useful for low temperature application and molecular engineering purposes in the future.
    Language English
    Publishing date 2024-03-13
    Publishing country United States
    Document type Journal Article
    ZDB-ID 806683-8
    ISSN 1097-0134 ; 0887-3585
    ISSN (online) 1097-0134
    ISSN 0887-3585
    DOI 10.1002/prot.26680
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