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  1. Article: Vacunas contra el coronavirus.

    Urbiztondo, L / Borràs, E / Mirada, G

    Vacunas

    2020  Volume 21, Issue 1, Page(s) 69–72

    Title translation Coronavirus vaccines.
    Keywords covid19
    Language Spanish
    Publishing date 2020-04-18
    Publishing country Spain
    Document type Journal Article
    ISSN 1576-9887
    ISSN 1576-9887
    DOI 10.1016/j.vacun.2020.04.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Unravelling the key factors in the chlorine-promoted epoxidation of ethylene over a silver-copper oxide nanocatalyst.

    Urbiztondo, Miguel / Ramirez, Adrian / Hueso, Jose L / Santamaria, Jesus / Ruiz-Salvador, A Rabdel / Hamad, Said

    Nanoscale

    2022  Volume 14, Issue 19, Page(s) 7332–7340

    Abstract: Ethylene oxide is one of the most important raw materials in the chemical industry, with an annual production close to 35 million metric tons. Despite its importance, to date, no metal has been found that can compete with the original silver bulk ... ...

    Abstract Ethylene oxide is one of the most important raw materials in the chemical industry, with an annual production close to 35 million metric tons. Despite its importance, to date, no metal has been found that can compete with the original silver bulk material catalyst discovered in 1931. Recently, a few copper and copper-silver based nanostructures have demonstrated remarkable selectivity and activity, especially when coupled with an industrial chlorine promoter. The present work evaluates the mechanistic role of chlorine as an active promoter of the selective oxidation of ethylene to ethylene oxide in the presence of a silver-copper oxide hybrid nanocatalyst (AgCuO). Experimental kinetic studies combined with density functional theory (DFT) calculations provide insight into the influence that Ag/CuO-supported chlorine atoms have over the ethylene epoxidation reaction. Remarkably, the typically described indirect route
    Language English
    Publishing date 2022-05-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 2515664-0
    ISSN 2040-3372 ; 2040-3364
    ISSN (online) 2040-3372
    ISSN 2040-3364
    DOI 10.1039/d2nr00702a
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Vacunas contra el coronavirus

    Urbiztondo, L. / Borràs, E. / Mirada, G.

    reponame:Expeditio Repositorio Institucional UJTL ; instname:Universidad de Bogotá Jorge Tadeo Lozano

    2020  

    Abstract: Es difícil aventurar cuándo se podrá disponer de vacunas contra la infección por coronavirus SARS-CoV-2. La aparición de la COVID-19 ha hecho pensar en las vacunas como la mejor manera de poder prevenirla, como ocurre habitualmente cuando aparece una ... ...

    Abstract Es difícil aventurar cuándo se podrá disponer de vacunas contra la infección por coronavirus SARS-CoV-2. La aparición de la COVID-19 ha hecho pensar en las vacunas como la mejor manera de poder prevenirla, como ocurre habitualmente cuando aparece una nueva enfermedad infecciosa. En los medios de comunicación generalistas aparecen continuamente noticias que prevén que habrá vacunas en pocos meses; sin embargo, en la prensa científica los artículos sobre este tema son relativamente escasos. Evidentemente, hay gran interés por conseguir vacunas contra esta enfermedad y hay numerosas empresas e instituciones académicas de todo el mundo que trabajan para conseguirlo. En el borrador proporcionado por la Organización Mundial de la Salud (OMS) con finalidad informativa, actualizado el 11 de abril, constan 70 productos candidatos a vacunas en evaluación: 3 vacunas en evaluación clínica y 67 en evaluación preclínica. La mayoría de estos productos se están desarrollando en laboratorios de investigación básica; si superan las primeras fases, deberán pasar a las industrias farmacéuticas con capacidad para realizar los ensayos clínicos necesarios para garantizar su eficacia y seguridad y el escalado de producción necesario para poner las vacunas al alcance de la población que las necesita. Más que de meses, la escala temporal para conseguir esto normalmente es de anos. ˜ No obstante, el enorme impacto humanitario y económico de la pandemia de COVID-19 está impulsando la evaluación de las plataformas de tecnología de vacunas de próxima generación a través de nuevos paradigmas para acelerar el desarrollo. De hecho, el primer candidato a la vacuna entró en evaluación clínica con una rapidez sin precedentes el 16 de marzo de 2020, teniendo en cuenta que la secuencia genética del SARS-CoV-2 se publicó el 11 de enero de 2020. Por esta razón, diferentes organismos sanitarios internacionales estiman en 12-18meses el tiempo necesario para disponer de una vacuna frente al SARS-CoV-2.
    Keywords Vacunas ; Coronavirus ; Síndrome respiratorio agudo grave ; COVID-19 ; SARS-CoV-2 ; Coronavirus vaccines ; covid19
    Publisher Get Personal Access to Vacunas
    Publishing country co
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Immunization recommendations against hepatitis A in Spain: Effectiveness of immunization in MSM and selection of antigenic variants.

    Urbiztondo, Luis / Pérez-Martin, Jaime J / Borràs-López, Eva / Navarro-Alonso, José A / Limia, Aurora

    EBioMedicine

    2019  Volume 45, Page(s) 19–20

    MeSH term(s) Hepatitis A ; Hepatitis A Antigens ; Hepatitis A virus/immunology ; Homosexuality, Male ; Humans ; Immunization ; Male ; Sexual and Gender Minorities ; Spain ; Vaccination
    Chemical Substances Hepatitis A Antigens
    Language English
    Publishing date 2019-06-25
    Publishing country Netherlands
    Document type Journal Article ; Comment
    ZDB-ID 2851331-9
    ISSN 2352-3964
    ISSN (online) 2352-3964
    DOI 10.1016/j.ebiom.2019.06.027
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 7090: Show issues Location:
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  7. Article: Decreasing Inappropriate Use of Antibiotics in Primary Care in Four Countries in South America-Cluster Randomized Controlled Trial.

    Urbiztondo, Inés / Bjerrum, Lars / Caballero, Lidia / Suarez, Miguel Angel / Olinisky, Monica / Córdoba, Gloria

    Antibiotics (Basel, Switzerland)

    2017  Volume 6, Issue 4

    Abstract: High antibiotic prescribing and antimicrobial resistance in patients attending primary care have been reported in South America. Very few interventions targeting general practitioners (GPs) to decrease inappropriate antibiotic prescribing have been ... ...

    Abstract High antibiotic prescribing and antimicrobial resistance in patients attending primary care have been reported in South America. Very few interventions targeting general practitioners (GPs) to decrease inappropriate antibiotic prescribing have been investigated in this region. This study assessed the effectiveness of online feedback on reducing antibiotic prescribing in patients with suspected respiratory tract infections (RTIs) attending primary care. The aim was to reduce antibiotic prescribing in patients with acute bronchitis and acute otitis media. Both are RTIs for which antibiotics have a very limited effect. A cluster randomized two-arm control trial was implemented. Healthcare centres from Bolivia, Argentina, Paraguay and Uruguay participating in the quality improvement program HAPPY AUDIT were randomly allocated to either intervention or control group. During ten consecutive weeks, GPs in the intervention group received evidence-based online feedback on the management of suspected RTIs. In patients with acute bronchitis, the intervention reduced the antibiotic prescribing rate from 71.6% to 56% (control group from 61.2% to 52%). In patients with acute otitis media, the intervention reduced the antibiotic prescribing from 94.8% to 86.2% (no change in the control group). In all RTIs, the intervention reduced antibiotic prescribing rate from 37.4% to 28.1% (control group from 29% to 27.2%). Online evidence-based feedback is effective for reducing antibiotic prescribing in patients with RTIs attending primary care in South America.
    Language English
    Publishing date 2017-12-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2681345-2
    ISSN 2079-6382
    ISSN 2079-6382
    DOI 10.3390/antibiotics6040038
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Recomendaciones autonómicas en vacunación de hepatitis en adultos infectados por el virus de la inmunodeficiencia humana: ¿disparidad basada en la evidencia?

    Mena, Guillermo / Vilajeliu, Alba / Urbiztondo, Luis / Bayas, José M

    Medicina clinica

    2015  Volume 145, Issue 4, Page(s) 163–170

    Title translation Regional recommendations on hepatitis vaccination in human immunodeficiency virus infected adult patients in Spain: Evidence-based disparity?.
    MeSH term(s) Adult ; Comorbidity ; Evidence-Based Medicine ; Guideline Adherence ; HIV Infections/epidemiology ; Hepatitis A Vaccines ; Hepatitis B Vaccines ; Hepatitis, Viral, Human/epidemiology ; Hepatitis, Viral, Human/prevention & control ; Humans ; Immunization Schedule ; Practice Guidelines as Topic ; Spain/epidemiology ; Vaccination/standards ; Vaccination/utilization
    Chemical Substances Hepatitis A Vaccines ; Hepatitis B Vaccines
    Language Spanish
    Publishing date 2015-08-21
    Publishing country Spain
    Document type Comparative Study ; Journal Article
    ZDB-ID 411607-0
    ISSN 1578-8989 ; 0025-7753
    ISSN (online) 1578-8989
    ISSN 0025-7753
    DOI 10.1016/j.medcli.2014.12.023
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ua VI Zs.279: Show issues Location:
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  9. Article: General Practitioners' Views on the Acceptability and Applicability of Using Quality Indicators as an Intervention to Reduce Unnecessary Prescription of Antibiotics in Four South American Countries.

    Urbiztondo, Inés / de Oliveira, Sandi Michele / Hernández-Flores, Nieves / Caballero, Lidia / Suarez, Miguel Angel / Bjerrum, Lars / Cordoba, Gloria

    Antibiotics (Basel, Switzerland)

    2018  Volume 7, Issue 3

    Abstract: As part of the quality improvement program “Health Alliance for Prudent Prescribing, Yield And Use of anti-microbial Drugs In the Treatment of respiratory tract infections” (HAPPY AUDIT) South America, we planned to implement an intervention based on the ...

    Abstract As part of the quality improvement program “Health Alliance for Prudent Prescribing, Yield And Use of anti-microbial Drugs In the Treatment of respiratory tract infections” (HAPPY AUDIT) South America, we planned to implement an intervention based on the use of quality indicators as a means to influence General Practitioners’ (GPs) prescribing decision. Knowledge on the acceptability and applicability of an intervention is crucial to decide whether the intervention is suitable and will achieve the expected outcomes. This study explores GPs’ views about the acceptability and applicability of using quality indicators as an intervention to influence their prescribing decision in patients with suspected Respiratory Tract Infections (RTIs) across four countries in South-America. In March 2015, GPs that were participating in HAPPY AUDIT South America were invited to participate in focus groups. A discussion guide covering the domains acceptability and applicability was used. Data was analyzed through systematic text condensation with an inductive approach. 171 GPs were invited and 48% participated. Acceptability ranged from totally acceptable to slightly acceptable. This spectrum of GPs views on acceptability was influenced by themes concerning applicability. In conclusion, there is a positive attitude towards the use of quality indicators. Nonetheless, applicability challenges have to be taken into consideration and solved if we are to achieve a large effect with the implementation of this intervention.
    Language English
    Publishing date 2018-07-05
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2681345-2
    ISSN 2079-6382
    ISSN 2079-6382
    DOI 10.3390/antibiotics7030057
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  10. Article ; Online: Impact of a single-age cohort human papillomavirus vaccination strategy in Catalonia, Spain: Population-based analysis of anogenital warts in men and women.

    Brotons, Maria / Monfil, Laura / Roura, Esther / Duarte-Salles, Talita / Casabona, Jordi / Urbiztondo, Luis / Cabezas, Carmen / Bosch, F Xavier / de Sanjosé, Silvia / Bruni, Laia

    Preventive medicine

    2020  Volume 138, Page(s) 106166

    Abstract: Extensive multiple-age cohort human papillomavirus (HPV) vaccination has proved to be highly effective. We aimed to determine the 8-year population impact of a female single-age cohort HPV vaccination programme on the incidence of anogenital warts (AGW). ...

    Abstract Extensive multiple-age cohort human papillomavirus (HPV) vaccination has proved to be highly effective. We aimed to determine the 8-year population impact of a female single-age cohort HPV vaccination programme on the incidence of anogenital warts (AGW). In 2008, Catalonia initiated a school-based quadrivalent HPV vaccination programme targeting 11-year-old girls, achieving coverage over 80%. Data on diagnoses of AGW and genital herpes were obtained from a population-based database of electronic health records covering 74% of the population. The annual incidence rates from 2009 to 2016 were calculated, stratified by age and sex using Joinpoint regression to estimate trends and annual percentage changes (APC). Among women aged 16-19 years, the AGW incidence decreased by 61% from 2012 to 2016 (APC -19.4%; 95% CI: -30.0 to -7.3). In contrast, the incidence of genital herpes in same-aged women increased throughout the study period (APC 11.1%; 95% CI: 7.2-15.2). Among men aged 20-22 years, the increasing incidence of AGW shifted to a downward trend in 2013 (APC 2009-2013: 17.0%; 95% CI: 8.2-26.5; and APC 2013-2016: -4.5%; 95% CI: -14.6 to 6.9). A similar pattern was observed among men aged 23-25 years (APC 2009-2014: 16.0%; 95% CI: 12.0-20.2; and APC 2014-2016: -6.0%; 95% CI: -18.4 to 8.3). In contrast to AGW, among men aged 20-25 years, the incidence of genital herpes increased over this period. Our study strongly suggests that a single-cohort HPV vaccination strategy with high vaccine uptake not only provides direct benefit in the vaccinated cohorts but also extends protection through a herd effect to unvaccinated men.
    MeSH term(s) Alphapapillomavirus ; Child ; Condylomata Acuminata/epidemiology ; Condylomata Acuminata/prevention & control ; Female ; Humans ; Incidence ; Male ; Papillomavirus Infections/epidemiology ; Papillomavirus Infections/prevention & control ; Papillomavirus Vaccines ; Spain/epidemiology ; Vaccination
    Chemical Substances Papillomavirus Vaccines
    Language English
    Publishing date 2020-06-18
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 184600-0
    ISSN 1096-0260 ; 0091-7435
    ISSN (online) 1096-0260
    ISSN 0091-7435
    DOI 10.1016/j.ypmed.2020.106166
    Database MEDical Literature Analysis and Retrieval System OnLINE

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