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Book ; Online: Relationship between malaria endemicity and acute febrile illness mortality in children [letter] / Daniel Chandramohan

Chandramohan, Daniel / Greenwood, Brian M / Cox, Jonathan / Mswia, Robert / Setel, Philip

2001

Keywords	Fever ; Malaria ; Altitude ; Child ; Preschool ; Tanzania ; Parasitic Diseases and their Control ; mortality etiology ; transmission complications
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Book ; Online: Relationship between malaria endemicity and acute febrile illness mortality in children [letter] / Daniel Chandramohan

Chandramohan, Daniel / Greenwood, Brian M / Cox, Jonathan / Mswia, Robert / Setel, Philip

2001

Keywords	Fever ; Malaria ; Altitude ; Child ; Preschool ; United Republic of Tanzania ; Parasitic Diseases and their Control ; mortality etiology ; transmission complications
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Validation and validity of verbal autopsy procedures.

Chandramohan, Daniel

Population health metrics

2011 Volume 9, Page(s) 22

Language	English
Publishing date	2011-08-01
Publishing country	England
Document type	Editorial
ZDB-ID	2127230-X
ISSN	1478-7954 ; 2155-7772
ISSN (online)	1478-7954
ISSN	2155-7772
DOI	10.1186/1478-7954-9-22
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Risk of active tuberculosis among people with diabetes mellitus: systematic review and meta-analysis.

Hayashi, Shintaro / Chandramohan, Daniel

Tropical medicine & international health : TM & IH

2018 Volume 23, Issue 10, Page(s) 1058–1070

Abstract: Objective: To assess the risk of active TB in people with DM and the factors associated with this risk.: Methods: Systematic review and meta-analysis. We searched the literature for studies that reported the effect of DM on TB controlled for the ... ...

Abstract	Objective: To assess the risk of active TB in people with DM and the factors associated with this risk. Methods: Systematic review and meta-analysis. We searched the literature for studies that reported the effect of DM on TB controlled for the effect of age. Studies that had not established the diagnosis of DM prior to detecting active TB were excluded. Study quality was assessed by Newcastle-Ottawa scale and we conducted a meta-analysis using random-effects models. Results: Of 14 studies (eight cohort and six case-control studies) that involved 22 616 623 participants met the selection criteria and were included in the analysis. There was substantial variation between studies in the estimates of the effect of DM on TB. However, the pooled estimates from seven high-quality studies showed that diabetic people have a 1.5-fold increased risk of developing active TB vs. those without DM (95%CI 1.28-1.76), with relatively small heterogeneity (I Conclusion: There is evidence suggesting an increased risk of developing TB among people with DM, and that improving glycaemic control in DM patients would reduce the risk of developing TB. An integrated approach is needed to control the dual burden of DM and TB.
MeSH term(s)	Causality ; Diabetes Complications/epidemiology ; Diabetes Mellitus/epidemiology ; Diabetes Mellitus, Type 2/epidemiology ; Female ; Humans ; Hyperglycemia/epidemiology ; Male ; Risk Factors ; Tuberculosis/epidemiology ; Tuberculosis, Multidrug-Resistant/epidemiology
Language	English
Publishing date	2018-08-29
Publishing country	England
Document type	Journal Article ; Meta-Analysis ; Systematic Review
ZDB-ID	1314080-2
ISSN	1365-3156 ; 1360-2276
ISSN (online)	1365-3156
ISSN	1360-2276
DOI	10.1111/tmi.13133
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Delivery strategies for malaria vaccination in areas with seasonal malaria transmission.

Grant, Jane / Diawara, Halimatou / Traore, Seydou / Koita, Fatoumata / Myers, Jessica / Sagara, Issaka / Chandramohan, Daniel / Dicko, Alassane / Greenwood, Brian / Webster, Jayne

BMJ global health

2023 Volume 8, Issue 5

Abstract: Background: Seasonal vaccination with the RTS,S/AS01: Methods: Potential delivery strategies for RTS,S/AS01: Results: Four delivery strategies were identified: age-based vaccination delivered via the Essential Programme on Immunisation (EPI); ... ...

Abstract	Background: Seasonal vaccination with the RTS,S/AS01 Methods: Potential delivery strategies for RTS,S/AS01 Results: Four delivery strategies were identified: age-based vaccination delivered via the Essential Programme on Immunisation (EPI); seasonal vaccination via EPI mass vaccination campaigns (MVCs); a combination of age-based priming vaccination doses delivered via the EPI clinics and seasonal booster doses delivered via MVCs; and a combination of age-based priming vaccination doses and seasonal booster doses, all delivered via the EPI clinics, which was the preferred strategy for delivery of RTS,S/AS01 Conclusions: Four delivery strategies were identified for administration of RTS,S/AS01
MeSH term(s)	Child ; Humans ; Child, Preschool ; Malaria Vaccines/therapeutic use ; Malaria, Falciparum/prevention & control ; Seasons ; Malaria/prevention & control ; Vaccination
Chemical Substances	Malaria Vaccines
Language	English
Publishing date	2023-04-20
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ISSN	2059-7908
ISSN	2059-7908
DOI	10.1136/bmjgh-2023-011838
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Article ; Online: Resurgent and delayed malaria.

Greenwood, Brian / Zongo, Issaka / Dicko, Alassane / Chandramohan, Daniel / Snow, Robert W / Ockenhouse, Christian

Malaria journal

2022 Volume 21, Issue 1, Page(s) 77

Abstract: The populations of moderate or highly malaria endemic areas gradually acquire some immunity to malaria as a result of repeated exposure to the infection. When this exposure is reduced as a result of effective malaria control measures, subjects who ... ...

Abstract	The populations of moderate or highly malaria endemic areas gradually acquire some immunity to malaria as a result of repeated exposure to the infection. When this exposure is reduced as a result of effective malaria control measures, subjects who benefitted from the intervention may consequently be at increased risk of malaria if the intervention is withdrawn, especially if this is done abruptly, and an effective malaria vector remains. There have been many examples of this occurring in the past, a phenomenon often termed 'rebound malaria', with the incidence of malaria rebounding to the level present before the intervention was introduced. Because the main clinical burden of malaria in areas with a high level of malaria transmission is in young children, malaria control efforts have, in recent decades, focussed on this group, with substantial success being obtained with interventions such as insecticide treated mosquito nets, chemoprevention and, most recently, malaria vaccines. These are interventions whose administration may not be sustained. This has led to concerns that in these circumstances, the overall burden of malaria in children may not be reduced but just delayed, with the main period of risk being in the period shortly after the intervention is no longer given. Although dependent on the same underlying process as classical 'resurgent' malaria, it may be helpful to differentiate the two conditions, describing the later as 'delayed malaria'. In this paper, some of the evidence that delayed malaria occurs is discussed and potential measures for reducing its impact are suggested.
MeSH term(s)	Animals ; Anopheles ; Child ; Child, Preschool ; Humans ; Insecticide-Treated Bednets ; Malaria/epidemiology ; Malaria/prevention & control ; Mosquito Control ; Mosquito Vectors
Language	English
Publishing date	2022-03-09
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	2091229-8
ISSN	1475-2875 ; 1475-2875
ISSN (online)	1475-2875
ISSN	1475-2875
DOI	10.1186/s12936-022-04098-6
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Involvement of single nucleotide polymorphisms of junction adhesion molecule with small vessel vascular dementia.

Xie, Peter / Kancherla, Kiran / Chandramohan, Sashiruben / Braidy, Nady / Chan, Eunice Kar Wing / Xu, Ying Hua / Chan, Daniel K Y

Aging medicine (Milton (N.S.W))

2023 Volume 6, Issue 4, Page(s) 347–352

Abstract: Objectives: It is now recognized that blood brain barrier (BBB) leakage occurs in cerebral small vascular disease (CSVD) and plays a significant role in the pathophysiology of vascular dementia. We hypothesized that genetic polymorphisms of junctional ... ...

Abstract	Objectives: It is now recognized that blood brain barrier (BBB) leakage occurs in cerebral small vascular disease (CSVD) and plays a significant role in the pathophysiology of vascular dementia. We hypothesized that genetic polymorphisms of junctional adhesion molecule-A (JAM-A) (which may result in compromised structure of tight junction proteins that form the BBB) in combination with cerebrovascular risk factors hypertension, lipid disorders, and type 2 diabetes may result in BBB leakage and increase the individual's risk of CSVD-related dementia. Methods: In this case-control study, 97 controls with a mean Mini-Mental State Exam (MMSE) score of 29 and 38 CSVD-related vascular dementia participants (mean MMSE score of 19) were recruited. Bloods were collected for the analysis of two common single nucleotide polymorphisms (SNPs) of the JAM-A genotypes rs790056 and rs2481084 using real-time polymerase chain reaction (PCR) assay. Medical history of hypertension, hyperlipidemia, and diabetes was collected for all participants. Results: Polymorphisms of genotype JAM-A SNP rs790056 showed statistically significant result when the subgroup with hyperlipidemia was analyzed (OR = 3.130, Conclusions: These results lend further support that cerebrovascular risk factors interact with genetic polymorphisms of BBB proteins to increase the risk of vascular dementia.
Language	English
Publishing date	2023-12-24
Publishing country	Australia
Document type	Journal Article
ISSN	2475-0360
ISSN (online)	2475-0360
DOI	10.1002/agm2.12278
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Coinfections of malaria and sexually transmitted and reproductive tract infections in pregnancy in sub-Saharan Africa: a systematic review and individual participant data meta-analysis protocol.

Sorano, Sumire / Gore-Langton, Georgia / Opondo, Charles / Smith, Chris / Matsui, Mitsuaki / Chaponda, Enesia Banda / Chandramohan, Daniel / Chico, R Matthew

BMJ open

2023 Volume 13, Issue 6, Page(s) e074896

Abstract: Introduction: Malaria infection and curable sexually transmitted infections and reproductive tract infections (STIs/RTIs) adversely impact pregnancy outcomes. In sub-Saharan Africa, the prevalence of malaria and curable STIs/RTIs is high and, where ... ...

Abstract	Introduction: Malaria infection and curable sexually transmitted infections and reproductive tract infections (STIs/RTIs) adversely impact pregnancy outcomes. In sub-Saharan Africa, the prevalence of malaria and curable STIs/RTIs is high and, where coinfection is common, combination interventions may be needed to improve pregnancy outcomes. The aim of this systematic review is to estimate the prevalence of malaria and curable STI/RTI coinfection during pregnancy, risk factors for coinfection and prevalence of associated adverse pregnancy outcomes. Methods and analysis: We will use three electronic databases, PubMed, EMBASE and Malaria in Pregnancy Library to identify studies involving pregnant women attending routine antenatal care facilities in sub-Saharan Africa and reporting malaria and curable STI/RTI test results, published in any language since 2000. We will search databases in the second quarter of 2023 and repeat the search before completion of our analyses. The first two authors will screen titles and abstracts, selecting studies that meet inclusion criteria and qualify for full-text screening. If agreement on inclusion/exclusion cannot be reached, the last author will serve as arbiter. We will extract data from eligible publications for a study-level meta-analysis. We will contact research groups of included studies and request individual participant data for meta-analysis. The first two authors will conduct a quality appraisal of included studies using the GRADE system. The last author will adjudicate if the first two authors do not agree on any appraisals. We will conduct sensitivity analyses to test the robustness of effect estimates over time (by decade and half-decade periods), geography (East/Southern Africa vs West/Central Africa), gravidity (primigravidae, secundigravidae, multigravidae), treatment type and dosing frequency, and malaria transmission intensity. Ethics and dissemination: We obtained ethics approval from the London School of Hygiene & Tropical Medicine (LSHTM Ethics Ref: 26167). Results of this study will be disseminated via peer-reviewed publication and presentation at scientific conferences. Prospero registration number: CRD42021224294.
MeSH term(s)	Humans ; Female ; Pregnancy ; Reproductive Tract Infections/epidemiology ; Coinfection/epidemiology ; Sexually Transmitted Diseases/prevention & control ; Malaria/epidemiology ; Malaria/prevention & control ; Pregnancy Outcome ; Africa South of the Sahara/epidemiology ; Systematic Reviews as Topic ; Meta-Analysis as Topic
Language	English
Publishing date	2023-06-20
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2599832-8
ISSN	2044-6055 ; 2044-6055
ISSN (online)	2044-6055
ISSN	2044-6055
DOI	10.1136/bmjopen-2023-074896
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Recovering biogas and nutrients via novel anaerobic co-digestion of pre-treated water hyacinth for the enhanced biogas production.

Daniel, Freedon / Sekar, M / Gavurová, Beata / Govindasamy, Chandramohan / Moorthy R, Krishnan / P, Boomadevi / T R, Praveenkumar

Environmental research

2023 Volume 231, Issue Pt 3, Page(s) 116216

Abstract: The present investigation explores the feasibility of generating biogas from water hyacinth (WH) through a pretreatment process. The WH samples were subjected to a high concentration of ... ...

Abstract	The present investigation explores the feasibility of generating biogas from water hyacinth (WH) through a pretreatment process. The WH samples were subjected to a high concentration of H
MeSH term(s)	Anaerobiosis ; Biofuels ; Eichhornia ; Methane ; Sewage ; Nutrients ; Digestion
Chemical Substances	Biofuels ; Methane (OP0UW79H66) ; Sewage
Language	English
Publishing date	2023-05-22
Publishing country	Netherlands
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	205699-9
ISSN	1096-0953 ; 0013-9351
ISSN (online)	1096-0953
ISSN	0013-9351
DOI	10.1016/j.envres.2023.116216
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Article ; Online: Validation and validity of verbal autopsy procedures

Chandramohan Daniel

Population Health Metrics, Vol 9, Iss 1, p

2011 Volume 22

Keywords	Computer applications to medicine. Medical informatics ; R858-859.7 ; Public aspects of medicine ; RA1-1270
Language	English
Publishing date	2011-08-01T00:00:00Z
Publisher	BMC
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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