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  1. Article ; Online: Does acral melanoma need a distinctive prognostic staging system?

    Carrera, Cristina / Podlipnik, Sebastian

    The British journal of dermatology

    2022  Volume 186, Issue 6, Page(s) 923–924

    MeSH term(s) Humans ; Melanoma ; Prognosis ; Skin Neoplasms ; Melanoma, Cutaneous Malignant
    Language English
    Publishing date 2022-05-03
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 80076-4
    ISSN 1365-2133 ; 0007-0963
    ISSN (online) 1365-2133
    ISSN 0007-0963
    DOI 10.1111/bjd.21585
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  2. Article: Teachers' Perceptions and Position Regarding the Problem of Bullying and Its Socio-Educational Prevention.

    Martínez-Carrera, Sara / Sánchez-Martínez, Cristina / Martínez-Carrera, Isabel / Dieguez, Miguel Ángel Díaz

    Behavioral sciences (Basel, Switzerland)

    2024  Volume 14, Issue 3

    Abstract: The problems that arise with coexistence between schoolchildren are a challenge when it comes to carrying out the teaching-learning process. In recent years, the presence of bullying has increased in schools. The aim of this study is to identify the ... ...

    Abstract The problems that arise with coexistence between schoolchildren are a challenge when it comes to carrying out the teaching-learning process. In recent years, the presence of bullying has increased in schools. The aim of this study is to identify the perceptions of teachers regarding the problems of coexistence among schoolchildren, more specifically concerning bullying, as well as to identify their position regarding the prevention of bullying. Research was carried out using a mixed approach. A total of 225 education professionals from different schools in Spain took part. From the results and our conclusions, it should be noted that teachers consider themselves to have a high level of knowledge of the essential characteristics of the dynamics of bullying, of the actors involved, and of some preventive measures that can be carried out to avoid this type of behaviour as much as possible. On the other hand, a large number of teachers downplay the importance of the problem of coexistence in their fields, and/or are not able to identify it, which makes it impossible to act. Some schools hardly carry out any prevention work, which makes it difficult to eradicate bullying.
    Language English
    Publishing date 2024-03-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2651997-5
    ISSN 2076-328X
    ISSN 2076-328X
    DOI 10.3390/bs14030229
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  3. Article ; Online: Melanoma on congenital melanocytic nevi.

    Alos, Llucia / Carrasco, Antonio / Teixidó, Cristina / Szumera-Ciećkiewicz, Anna / Vicente, Asunción / Massi, Daniela / Carrera, Cristina

    Pathology, research and practice

    2024  Volume 256, Page(s) 155262

    Abstract: Among nevus-associated melanomas, which overall account for 20%-30% of all melanomas, those arising specifically in congenital melanocytic nevi are infrequent, but can be disproportionately frequent in childhood and adolescence. Congenital melanocytic ... ...

    Abstract Among nevus-associated melanomas, which overall account for 20%-30% of all melanomas, those arising specifically in congenital melanocytic nevi are infrequent, but can be disproportionately frequent in childhood and adolescence. Congenital melanocytic nevi (CMNi) are common benign melanocytic tumors that are present at birth or become apparent in early childhood. They are classified based on the projected adult size. Small and medium-sized CMNi are frequent, whereas large/giant CMNi (over 20 cm in diameter) are rare, but can be associated with high morbidity due to marked aesthetic impairment and the risk of neurocutaneous syndrome or melanoma development. In this setting, melanomas can appear in early childhood and are very aggressive, while the risk of small-medium CMNi of developing melanoma is low and similar to non-congenital melanocytic nevi. Histologically, most melanomas on CMNi initiate their growth at the epidermal-dermal junction, but in large/giant CMNi they can develop entirely in the dermis, in deeper tissues, or in extracutaneous sites (especially in the central nervous system). Most CMNi harbour an NRAS mutation, but other genes are rarely involved, and gene translocations have recently been described. However, no prognostic implications have been associated with the CMN genotype. Melanomas developed on CMNi harbour additional molecular alterations to which the aggressive clinical course of these tumors has been attributed. This review covers the distinctive clinical and pathological aspects of melanomas on CMNi, and includes the epidemiology, etiopathogenesis, clinical and dermoscopic presentation, histological and molecular characteristics, as well as tumour behaviour.
    MeSH term(s) Adult ; Infant, Newborn ; Adolescent ; Humans ; Child, Preschool ; Melanoma/genetics ; Melanoma/pathology ; Skin Neoplasms/genetics ; Skin Neoplasms/pathology ; Nevus, Pigmented/genetics ; Nevus, Epithelioid and Spindle Cell ; Nitroimidazoles
    Chemical Substances 1-methyl-5-chloro-4-nitroimidazole (P917JW98BD) ; Nitroimidazoles
    Language English
    Publishing date 2024-03-11
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 391889-0
    ISSN 1618-0631 ; 0344-0338
    ISSN (online) 1618-0631
    ISSN 0344-0338
    DOI 10.1016/j.prp.2024.155262
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  4. Article ; Online: Improving teleophthalmology protocols in high-occupancy, high-demand, and remote settings.

    Cañizares, Stalin / Torres, María Belen / Carrera, Gabriela / Ruiz, Cristina / Gabela, María Cristina / Ocampo, Jaime / Caicedo, Andrés

    Eye (London, England)

    2023  Volume 38, Issue 2, Page(s) 406–407

    MeSH term(s) Humans ; Telemedicine/methods ; Ophthalmology/methods ; Diabetic Retinopathy
    Language English
    Publishing date 2023-08-16
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 91001-6
    ISSN 1476-5454 ; 0950-222X
    ISSN (online) 1476-5454
    ISSN 0950-222X
    DOI 10.1038/s41433-023-02701-x
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  5. Article ; Online: Solitary palmar adult xanthogranuloma.

    Serra-García, Laura / Carrera, Cristina / Giavedoni, Priscila / Riquelme-Mc Loughlin, Constanza

    Anais brasileiros de dermatologia

    2023  Volume 99, Issue 2, Page(s) 302–304

    MeSH term(s) Adult ; Humans ; Skin ; Xanthogranuloma, Juvenile ; Skin Neoplasms
    Language English
    Publishing date 2023-11-22
    Publishing country Spain
    Document type Case Reports
    ZDB-ID 433655-0
    ISSN 1806-4841 ; 0365-0596
    ISSN (online) 1806-4841
    ISSN 0365-0596
    DOI 10.1016/j.abd.2022.10.014
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  6. Article ; Online: Prognostic Value of the Neutrophil-to-lymphocyte Ratio, Platelet-to- lymphocyte Ratio and Monocyte-to-lymphocyte Ratio in Melanoma Patients: A Cohort Study.

    Ertekin, Sümeyre Seda / Mangas, Cristina / Riquelme-Mc Loughlin, Constanza / Carrera, Cristina / Malvehy, Josep / Puig, Susana / Podlipnik, Sebastian

    Acta dermato-venereologica

    2024  Volume 104, Page(s) adv27571

    Abstract: The prognostic value of the neutrophil-lymphocyte ratio, platelet-lymphocyte ratio and monocyte-lymphocyte ratio in patients with melanoma has yielded controversial results in the literature. A retrospective single-centre cohort study was conducted from ... ...

    Abstract The prognostic value of the neutrophil-lymphocyte ratio, platelet-lymphocyte ratio and monocyte-lymphocyte ratio in patients with melanoma has yielded controversial results in the literature. A retrospective single-centre cohort study was conducted from 1998 to 2020, including patients diagnosed with invasive melanoma. A total of 2,721 patients were included in the study. The median follow-up was 8.23 years (IQR 4.41-13.25). The median baseline neutrophil- lymphocyte ratio, platelet-lymphocyte ratio and monocyte-lymphocyte ratio values increased significantly (p < 0.001) with the increasing American Joint Committee on Cancer stage. The optimal cut-off values for neutrophil-lymphocyte ratio, platelet-lymphocyte ratio and monocyte-lymphocyte ratio were determined as 2.1, 184 and 0.2, respectively. In the multivariate analysis, high levels of neutrophil-lymphocyte ratio (≥ 2.1), platelet-lymphocyte ratio (≥ 184) and monocyte-lymphocyte ratio (≥ 0.2) were independently associated with significantly shorter melanoma-specific survival (neutrophil-lymphocyte ratio: HR 1.30, 95% CI 1.06-1.60, p = 0.013; platelet-lymphocyte ratio: HR 1.37, 95% CI 1.06-1.76, p = 0.014; monocyte- lymphocyte ratio: HR 1.29, 95% CI 1.05-1.58, p = 0.015) and overall survival (neutrophil-lymphocyte ratio: HR 1.39, 95% CI 1.19-1.64, p < 0.001; platelet- lymphocyte ratio: HR 1.44, 95% CI 1.19-1.74, p < 0.001; monocyte-lymphocyte ratio: HR 1.42, 95% CI 1.21-1.66, p < 0.001). High levels of neutrophil- lymphocyte ratio and monocyte-lymphocyte ratio were also associated with poor relapse-free survival, while platelet-lymphocyte ratio was not. In conclusion, baseline neutrophil-lymphocyte ratio, platelet-lymphocyte ratio and monocyte-lymphocyte ratio were identified as independent predictors for the prognosis of melanoma.
    MeSH term(s) Humans ; Melanoma/blood ; Melanoma/mortality ; Melanoma/pathology ; Melanoma/immunology ; Male ; Female ; Neutrophils ; Retrospective Studies ; Middle Aged ; Skin Neoplasms/blood ; Skin Neoplasms/pathology ; Skin Neoplasms/mortality ; Skin Neoplasms/immunology ; Monocytes ; Prognosis ; Lymphocyte Count ; Platelet Count ; Lymphocytes ; Blood Platelets/pathology ; Aged ; Adult ; Predictive Value of Tests ; Leukocyte Count ; Neoplasm Staging ; Time Factors
    Language English
    Publishing date 2024-04-24
    Publishing country Sweden
    Document type Journal Article
    ZDB-ID 80007-7
    ISSN 1651-2057 ; 0001-5555
    ISSN (online) 1651-2057
    ISSN 0001-5555
    DOI 10.2340/actadv.v104.27571
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  7. Article ; Online: Polymorphic rupioid psoriasis with chamomile-like lesions: A case report.

    Aromolo, Italo Francesco / Riva, Davide / Cattaneo, Angelo / Carrera, Carlo Giovanni / Spigariolo, Cristina Beatrice / Marzano, Angelo Valerio

    Journal of the European Academy of Dermatology and Venereology : JEADV

    2023  Volume 37, Issue 6, Page(s) e726–e728

    MeSH term(s) Humans ; Chamomile ; Psoriasis/diagnosis ; Exanthema ; Plant Extracts
    Chemical Substances Plant Extracts
    Language English
    Publishing date 2023-01-31
    Publishing country England
    Document type Case Reports ; Letter
    ZDB-ID 1128828-0
    ISSN 1468-3083 ; 0926-9959
    ISSN (online) 1468-3083
    ISSN 0926-9959
    DOI 10.1111/jdv.18888
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    Zs.MO 413: Show issues

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  8. Article: Squamous Cell Carcinoma: An Update on Diagnosis and Treatment.

    Combalia, Andrea / Carrera, Cristina

    Dermatology practical & conceptual

    2020  Volume 10, Issue 3, Page(s) e2020066

    Abstract: Squamous cell carcinoma (SCC) accounts for most nonmelanoma skin cancer-related metastatic disease and deaths. Histopathology and correct surgical excision remain the gold standard for the diagnosis and treatment of SCC; however, new diagnostic imaging ... ...

    Abstract Squamous cell carcinoma (SCC) accounts for most nonmelanoma skin cancer-related metastatic disease and deaths. Histopathology and correct surgical excision remain the gold standard for the diagnosis and treatment of SCC; however, new diagnostic imaging techniques such as dermoscopy and reflectance confocal microscopy have increased the diagnostic accuracy in terms of early recognition, better differential diagnosis, more precise selection of areas to biopsy, and noninvasive monitoring of treatments. The therapeutic intervention in patients with severe actinic damage and multiple in situ/low-risk SCC, and the development of innovative treatments such as epidermal growth factor receptor inhibitors and immune checkpoint inhibitors for locally advanced and metastatic SCC, are improving considerably the approach to the disease. This review summarizes the up-to-date knowledge in the field of detection, treatment, and monitoring of cutaneous SCC.
    Language English
    Publishing date 2020-06-29
    Publishing country Austria
    Document type Journal Article ; Review
    ZDB-ID 2685397-8
    ISSN 2160-9381
    ISSN 2160-9381
    DOI 10.5826/dpc.1003a66
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  9. Article ; Online: Efectos de la densidad de cultivo y de proteína en la dieta sobre el desempeño del capaz (Pimelodus grosskopfii) en estanques

    Silvia Cristina Carrera

    Mutis, Vol 9, Iss 2, Pp 25-

    2019  Volume 33

    Abstract: La diversificación de la piscicultura colombiana se restringe sobre aquellas especies calificadas como promisorias. En el grupo de los silúridos se tienen representantes sobre los que se ha logrado estabilizar algún nivel de constante esfuerzo ... ...

    Abstract La diversificación de la piscicultura colombiana se restringe sobre aquellas especies calificadas como promisorias. En el grupo de los silúridos se tienen representantes sobre los que se ha logrado estabilizar algún nivel de constante esfuerzo experimental en el país. En particular, con el capaz (Pimelodus grosskopfii) los desarrollos alcanzados se centran en la estandarización de manejo reproductivo, pero la información sobre su comportamiento en condiciones de cultivo aún es deficiente. En un estanque en tierra se manejaron alevinos de capaz obtenidos por reproducción artificial en tres densidades de siembra (2, 3 y 4 peces m-2), a los que se suministró concentrado comercial de 25 y 32 % de proteína bruta (pb); se configuró un diseño con un total de 6 tratamientos, cada uno con tres réplicas. El seguimiento se realizó durante 6 meses con muestreos quincenales en los que se evaluó el desempeño. El monitoreo de calidad del agua fue constante durante el periodo. En el crecimiento se demostró una interacción significativa (α = 0,05) entre la densidad de siembra y el porcentaje de proteína en la dieta. Se registró un mayor desempeño con 25 % pb y en densidades de siembra de 2 y 4 peces m-2.
    Keywords p. grosskopfii ; cultivo ; crop ; densidad de siembra ; seeding density ; crecimiento ; growth ; estanques en tierra ; ponds on land ; Science ; Q ; Science (General) ; Q1-390 ; Social sciences (General) ; H1-99
    Language English
    Publishing date 2019-12-01T00:00:00Z
    Publisher Universidad Jorge Tadeo Lozano
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Utilization of medical interventions in hospitalized Mexican adults with cancer at the end of life in a referral hospital: The importance of early palliative care.

    Allende-Pérez, Silvia Rosa / Sandoval-Carrera, Nadia Cristina / Asencio-Huertas, Leticia / Rodríguez-Mayoral, Oscar / Cruz-Sánchez, Jacob Jonatan / Verástegui-Avilés, Emma

    Palliative & supportive care

    2024  , Page(s) 1–8

    Abstract: Objectives: To investigate the impact of early vs. late palliative care (PC) on the frequency of admissions to acute hospital settings and the utilization of end-of-life (EoL) interventions in cancer decedents.: Methods: In this single-center, cross- ... ...

    Abstract Objectives: To investigate the impact of early vs. late palliative care (PC) on the frequency of admissions to acute hospital settings and the utilization of end-of-life (EoL) interventions in cancer decedents.
    Methods: In this single-center, cross-sectional study, we examined the frequency of intensive care unit (ICU) and emergency department (ED) admissions among adult cancer decedents between 2018 and 2022 in a referral hospital in México. Additionally, we assessed EoL medical interventions, categorizing patients into 3 groups: those who received early PC (EPC), late PC (LPC), and those who did not receive PC (NPC).
    Results: We analyzed data from 1762 patients, averaging 56 ± 16.3 years old, with a predominant representation of women (56.8%). PC was administered to 45.2% of patients, but EPC was limited to only 12.3%. The median time from the initiation of PC to death was 5 days (interquartile range: 2.0-31.5). Hematological malignancies were the most prevalent, affecting 21.5% of patients. EPC recipients demonstrated notable reductions in ICU and ED admissions, as well as diminished utilization of chemotherapy, radiotherapy (RT), antibiotics, blood transfusions, and surgery when compared to both LPC and NPC groups. EPC also exhibited fewer medical interventions in the last 14 days of life, except for RT.
    Significance of results: The findings of this study indicate that a significant proportion of EoL cancer patients receive PC; however, few receive EPC, emphasizing the need to improve accessibility to these services. Moreover, the results underscore the importance of thoughtful deliberation regarding the application of EoL medical interventions in cancer patients.
    Language English
    Publishing date 2024-03-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 2454009-2
    ISSN 1478-9523 ; 1478-9515
    ISSN (online) 1478-9523
    ISSN 1478-9515
    DOI 10.1017/S1478951524000051
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