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  1. Article ; Online: Development and implementation of sexual and gender minority curriculum for advanced practice nursing: A feasibility study.

    Tsusaki, Rebecca / Mullassery, Daisy / Ramaswamy, Padmavathy

    Journal of advanced nursing

    2024  

    Abstract: Aim: To explore the feasibility of development and implementation of an educational intervention addressing sexual and gender minority healthcare issues; examine recruitment processes and instrument appropriateness.: Design: Non-randomized ... ...

    Abstract Aim: To explore the feasibility of development and implementation of an educational intervention addressing sexual and gender minority healthcare issues; examine recruitment processes and instrument appropriateness.
    Design: Non-randomized feasibility study.
    Methods: The educational intervention was developed and implemented in family nurse practitioner courses with data collection from August through December 2022. Clinical preparedness, attitudinal awareness and basic knowledge were measured using the lesbian, gay, bisexual and transgender Development of Clinical Skills Scale.
    Results: Development and implementation of the intervention was feasible but will require amendment before progressing to the pilot study. Clinical preparedness and basic knowledge increased post-intervention, but attitudinal awareness did not improve. Recruitment did not achieve the desired sample size. Instrument internal consistency reliability was confirmed.
    Conclusion: Feasibility was established but will require amendment prior to the pilot study.
    Implications for the profession and/or patient care: To prepare nurses and nurse practitioners to care for sexual and gender minority patients.
    Impact: This study addressed the feasibility of developing and implementing a sexual and gender minority healthcare education using an e-Learning platform. Findings confirm that the intervention was feasible but will require amendment. The intervention increased knowledge and clinical preparedness in caring for this population, but recruitment was challenging. This research will impact nurses, nurse practitioners and nurse educators.
    Reporting method: The authors adhered to the relevant EQUATOR guidelines. The Consolidated Standards of Reporting Trials guideline extension for reporting randomized and feasibility guidelines were used.
    Public contribution: Sexual and gender minority community members contributed to the intervention development. WHAT DOES THIS PAPER CONTRIBUTE TO THE WIDER GLOBAL CLINICAL COMMUNITY?: The feasibility of using interactive e-learning educational resources to provide sexual and gender minority healthcare curriculum. Evidence to support the use of the Lesbian, Gay, Bisexual, and Transgender Development of Clinical Skills Scale to measure learning outcomes.
    Trial registration: This study was not prospectively registered because it was an educational intervention involving graduate student nurses and did not assess clinical outcomes of patients.
    Language English
    Publishing date 2024-01-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 197634-5
    ISSN 1365-2648 ; 0309-2402
    ISSN (online) 1365-2648
    ISSN 0309-2402
    DOI 10.1111/jan.16051
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    Zs.B 1851: Show issues Location:
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  2. Article ; Online: Stress, Grit, Satisfaction With Life, and Remediation of Prelicensure Nursing Students.

    Tsusaki, Rebecca / Mullassery, Daisy / Ramaswamy, Padmavathy

    Nurse educator

    2023  Volume 49, Issue 1, Page(s) 19–24

    Abstract: Background: Stress and poor academic performance often lead to high levels of nursing school attrition.: Purpose: To explore nursing students' perceived stress, grit, and satisfaction with life, and assess the effectiveness of a remediation program ... ...

    Abstract Background: Stress and poor academic performance often lead to high levels of nursing school attrition.
    Purpose: To explore nursing students' perceived stress, grit, and satisfaction with life, and assess the effectiveness of a remediation program for students at risk for poor academic performance.
    Methods: Perceived stress, grit, and satisfaction with life were measured, and the effect of remediation given to at-risk students was studied. Examination and psychometric scores were compared between remediation and nonremediation groups.
    Results: The remediation group had higher levels of perceived stress and a lower satisfaction with life compared with the rest of the cohort. Remediation significantly improved examination scores of at-risk students although scores remained lower than those among nonremediation students.
    Conclusions: Perceived stress and grit scores were high in nursing students, and satisfaction varied among age groups. Remediation based on metacognitive theory significantly improved at-risk students' examination scores.
    MeSH term(s) Humans ; Students, Nursing/psychology ; Surveys and Questionnaires ; Nursing Education Research ; Personal Satisfaction ; Psychometrics
    Language English
    Publishing date 2023-07-13
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1034267-9
    ISSN 1538-9855 ; 0363-3624
    ISSN (online) 1538-9855
    ISSN 0363-3624
    DOI 10.1097/NNE.0000000000001481
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    Zs.A 2904: Show issues Location:
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  3. Article ; Online: Biochar-ZnO/polyaniline composite in energy storage application

    Diana Thomas / Noeline B. Fernandez / Manohar D Mullassery / R. Surya

    Results in Chemistry, Vol 6, Iss , Pp 101061- (2023)

    Synthesis, characterization and electrochemical analysis

    2023  

    Abstract: Carbon materials displaying electrical double layer capacitance are widely used in the electrochemical energy storage devices. To enhance the electrochemical performance, compositing carbon with transition metal oxides and conducting polymers have been ... ...

    Abstract Carbon materials displaying electrical double layer capacitance are widely used in the electrochemical energy storage devices. To enhance the electrochemical performance, compositing carbon with transition metal oxides and conducting polymers have been very much appreciated. A novel and effective approach to prepare a high energy density and high specific capacitance composite electrode material from a biomass is presented in the work. Pyrolysis of biomass at 500 °C in the nitrogen atmosphere yielded a biochar (BC) with well-developed porosity, surface functionality and suitable morphological characteristics. Anchoring ZnO nanoparticles on BC and subsequently coating it with a conducting polymeric material, polyaniline (PANI) obtained the hierarchical BC-ZnO/PANI composite. Both BC-ZnO and BC-ZnO/PANI composites have been characterized by FTIR, UV–Visible, XRD, SEM and TEM studies. The characteristic signals at 2θ values 18.5°, 28.4°, 24.0° and 31.4° in XRD correspond to wurtzite structure of ZnO nanoparticles. ZnO rod like structural morphology was confirmed by SEM analysis. The maximum specific capacitance was found to be 110.0 F/g for BC-ZnO and 198.0 F/g for BC-ZnO/PANI. The ternary composite displayed low solution resistance and charge transfer resistance as evident from the Nyquist plots. The results proved that PANI coating is a promising methodology in the fabrication of electrode materials for energy storage applications.
    Keywords Biochar ; Super capacitor ; PANI ; ZnO ; Chemistry ; QD1-999
    Subject code 620
    Language English
    Publishing date 2023-12-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
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  4. Article ; Online: Current treatment and outcomes of pediatric gastrointestinal stromal tumors (GIST): a systematic review of published studies.

    Raitio, Arimatias / Salim, Adeline / Mullassery, Dhanya / Losty, Paul D

    Pediatric surgery international

    2021  Volume 37, Issue 9, Page(s) 1161–1165

    Abstract: Gastrointestinal stromal tumor (GIST) is a rare cancer of mesenchymal origin mostly seen in adult and elderly populations. Therefore, the prognostic and therapeutic features of pediatric GIST are not clearly defined. Clinical knowledge has been largely ... ...

    Abstract Gastrointestinal stromal tumor (GIST) is a rare cancer of mesenchymal origin mostly seen in adult and elderly populations. Therefore, the prognostic and therapeutic features of pediatric GIST are not clearly defined. Clinical knowledge has been largely extrapolated from case series and adult studies. In this systematic review, we aimed to analyze the health outcome metrics of pediatric GIST. Medline and Embase databases were searched using relevant key terms. The original search retrieved 1,892 titles; 27 studies with 184 patients (68% female) were included for final review. The primary tumors were located in the stomach (165/184, 90%), small bowel (12/184, 7%), and elsewhere (7/184, 4%). Individual patient data were available in 125 cases with a median follow-up of 6.7 years. All patients underwent surgical resection, which varied from wide local excision to total gastrectomy. There were 12 deaths (10%), 65 (52%) patients were alive with no evidence of disease, and 31 cases (25%) were alive with disease. Tumor size > 5 cm, high mitotic index, and spindle morphology were predictive of mortality. Pediatric GIST has a more favorable prognosis and different characteristics versus adult tumors. There is a crucial need for international consensus and specific pediatric guidelines for the treatment of this rare tumor.
    MeSH term(s) Adult ; Aged ; Child ; Female ; Gastrointestinal Stromal Tumors/epidemiology ; Gastrointestinal Stromal Tumors/surgery ; Humans ; Intestine, Small ; Male ; Prognosis ; Retrospective Studies ; Treatment Outcome
    Language English
    Publishing date 2021-06-03
    Publishing country Germany
    Document type Journal Article ; Review ; Systematic Review
    ZDB-ID 632773-4
    ISSN 1437-9813 ; 0179-0358
    ISSN (online) 1437-9813
    ISSN 0179-0358
    DOI 10.1007/s00383-021-04931-0
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    Zs.A 2138: Show issues Location:
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  5. Article ; Online: Experiential Skills Laboratory Experiences in a Didactic Undergraduate Reproductive Health Course.

    Tsusaki, Rebecca / Ethington, Melissa D / Helmreich, Rebecca J / Mullassery, Daisy G / Ramaswamy, Padmavathy

    The Journal of nursing education

    2022  Volume 61, Issue 6, Page(s) 326–329

    Abstract: Background: Experiential learning provides undergraduate nursing students with hands-on opportunities to integrate knowledge and clinical skills. Using educational theory, nurse educators can integrate experiential laboratory experiences into didactic ... ...

    Abstract Background: Experiential learning provides undergraduate nursing students with hands-on opportunities to integrate knowledge and clinical skills. Using educational theory, nurse educators can integrate experiential laboratory experiences into didactic courses to increase comprehension of knowledge and skills required in the clinical setting.
    Method: Experiential laboratory experiences were coordinated with didactic content in an undergraduate reproductive health course, and student scores on weekly quizzes and a standardized final examination were compared for three cohorts. One cohort participated in a generic laboratory at the start of the semester, one cohort received 4 synchronized laboratory days throughout the semester, and another cohort received the same content in 2-day laboratory sessions.
    Results: Weekly quiz scores and standardized final examination scores were significantly higher among students who had synchronized experiential laboratory experiences than for students who had a generic laboratory experience.
    Conclusion: Experiential laboratory experiences are helpful in integrating clinical skills and course knowledge comprehension in didactic undergraduate courses.
    MeSH term(s) Clinical Competence ; Education, Nursing, Baccalaureate ; Humans ; Problem-Based Learning ; Reproductive Health ; Students, Nursing
    Language English
    Publishing date 2022-06-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 410686-6
    ISSN 1938-2421 ; 0148-4834
    ISSN (online) 1938-2421
    ISSN 0148-4834
    DOI 10.3928/01484834-20220404-11
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    Zs.B 616: Show issues Location:
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  6. Article ; Online: Banana stem biochar composite with polyaniline for energy storage applications

    Diana Thomas / Noeline B. Fernandez / Manohar D. Mullassery / R. Surya / Linda E. Jacob

    Results in Chemistry, Vol 6, Iss , Pp 101088- (2023)

    2023  

    Abstract: The production and use of activated carbon from biochar, exclusively for energy storage and environmental applications was attracting attention. In this work, the commonly available banana stem was selected as a precursor to be converted into biochar (BC) ...

    Abstract The production and use of activated carbon from biochar, exclusively for energy storage and environmental applications was attracting attention. In this work, the commonly available banana stem was selected as a precursor to be converted into biochar (BC) at 500℃. The conducting polymer poly aniline (PANI) was then incorporated into the char matrix (BC-PANI) in order to improve the electrical properties. FTIR, UV–visible, XRD, SEM and TEM techniques were used to characterize the polymer composite. The integration PANI onto BC was clearly revealed from SEM and TEM micrographs and also the nanocomposite formation (BC-PANI, 0.37 nm) was confirmed from the XRD analysis. Furthermore, the electrochemical performance was analyzed using cyclicvoltammetry and electrochemical impedance spectroscopy. Both BC and BC-PANI attained maximum specific capacitance of 27.00 and 57.50 Fg−1 respectively. The various resistance that originated at electrode/electrolyte interface was also identified from impedance spectroscopy. These findings highlighted the good capacitive nature of the electrode material (BC-PANI).
    Keywords Chemistry ; QD1-999
    Subject code 540
    Language English
    Publishing date 2023-12-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
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  7. Article ; Online: Short and Medium Term Outcomes of Open and Laparoscopic Assisted Oesophageal Replacement Procedures.

    Maher, Ahmed / De Coppi, Paolo / Blackburn, Simon / Loukogeorgakis, Stavros / Eaton, Simon / Cross, Kate / Giuliani, Stefano / Curry, Joe / Mullassery, Dhanya

    Journal of pediatric surgery

    2023  Volume 59, Issue 2, Page(s) 192–196

    Abstract: Aim of the study: We describe the short- and medium-term outcomes following open and laparoscopic assisted oesophageal replacement surgery in a single tertiary paediatric surgical centre.: Methods: A retrospective review (institutional audit approval ...

    Abstract Aim of the study: We describe the short- and medium-term outcomes following open and laparoscopic assisted oesophageal replacement surgery in a single tertiary paediatric surgical centre.
    Methods: A retrospective review (institutional audit approval no. 3213) on patients who underwent open or laparoscopic-assisted oesophageal replacement (OAR vs. LAR) at our centre between 2002 and 2021 was completed. Data collected (demographics, early complications, stricture formation, need for oesophageal dilatations, and mortality) were analysed using GraphPad Prism v 9.50 and are presented as median (IQR).
    Results: 71 children (37 male) had oesophageal replacement surgery at a median age of 2.3 years (IQR 4.7 years). 51 were LAR (6 conversions). Replacement conduit was stomach (n = 67), colon (n = 3), or jejunum (n = 1). Most gastric transpositions had a pyloroplasty (46/67) or pyloromyotomy (14/67). Most common pathology was oesophageal atresia (n = 50 including 2 failed transpositions), caustic injury (n = 19 including 3 due to button battery), stricture of unknown cause (n = 1), and megaoesophagus (n = 1). There were 2 (2.8 %) early postoperative deaths at 2 days (major vessel thrombosis), 1 month (systemic sepsis), and one death at 5 years in the community. The rate of postoperative complications were comparable across LAR and OAR including anastomotic leak, pleural effusions, or early strictures. More patients with caustic pathology needed dilatations (60 % vs 30 % in OA, p = 0.05).
    Conclusions: Outcomes of open and laparoscopic-assisted oesophageal replacement procedures are comparable in the short and medium term. Anastomotic stricture is higher in those with caustic injury.
    Level of evidence: IV.
    MeSH term(s) Child ; Humans ; Male ; Child, Preschool ; Esophageal Stenosis/epidemiology ; Esophageal Stenosis/etiology ; Esophageal Stenosis/surgery ; Constriction, Pathologic/surgery ; Caustics ; Esophageal Atresia/surgery ; Esophageal Atresia/complications ; Postoperative Complications/epidemiology ; Postoperative Complications/etiology ; Postoperative Complications/surgery ; Laparoscopy/methods ; Retrospective Studies
    Chemical Substances Caustics
    Language English
    Publishing date 2023-10-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80165-3
    ISSN 1531-5037 ; 0022-3468
    ISSN (online) 1531-5037
    ISSN 0022-3468
    DOI 10.1016/j.jpedsurg.2023.10.015
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    Zs.A 607: Show issues Location:
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  8. Article ; Online: Stage 4S Neuroblastoma: What Are the Outcomes? A Systematic Review of Published Studies.

    Raitio, Arimatias / Rice, Michael J / Mullassery, Dhanya / Losty, Paul D

    European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie

    2020  Volume 31, Issue 5, Page(s) 385–389

    Abstract: Introduction:  The prognosis of stage 4S/MS neuroblastoma has traditionally been reported as excellent, yet conflicting treatment protocols exist for this enigmatic disease. To critically address this question, we have undertaken a systematic review of ... ...

    Abstract Introduction:  The prognosis of stage 4S/MS neuroblastoma has traditionally been reported as excellent, yet conflicting treatment protocols exist for this enigmatic disease. To critically address this question, we have undertaken a systematic review of published studies to accurately determine outcomes for infants with stage 4S/MS neuroblastoma.
    Materials and methods:  Studies were identified using MEDLINE, Embase, and Cochrane databases using the relevant search terms. Literature reviews, case reports, and adult studies were excluded. Data were extracted independently following article selection by three authors and reviewed by the senior author.
    Results:  The original search retrieved 2,325 articles. Following application of exclusion criteria and removing duplicate data, 37 studies (1,105 patients) were included for final review. Overall patient survival was 84%. Twelve studies (544 patients) recorded MYCN status. Mortality in MYCN amplified tumors was 56%. Chromosome 1p/11q status was reported in four studies and 1p/11q deletion carried a 40% fatality rate. Management included observation only (201 patients, 8.5% mortality), surgical resection of primary tumor only (153 patients, 6.5% mortality), chemotherapy only (186 patients, 21% mortality), radiotherapy (5 deaths, 33% mortality), chemotherapy with surgery (160 patients, 10% mortality), surgery with radiotherapy (21 patients, 19% mortality), radiotherapy with chemotherapy (42 patients, 29% mortality), and surgery with chemotherapy and radiotherapy (27 patients, 33% mortality).
    Conclusion:  There is a significant mortality observed in stage 4S/MS neuroblastoma infants with a dismal outcome observed in those patients with MYCN amplification and 1p/11q deletion. Those patients suitably amenable for conservative management or surgery to excise the primary tumor carry the best prognosis.
    MeSH term(s) Humans ; Infant ; Infant, Newborn ; N-Myc Proto-Oncogene Protein ; Neoplasm Staging ; Neuroblastoma/genetics ; Neuroblastoma/mortality ; Neuroblastoma/therapy
    Chemical Substances MYCN protein, human ; N-Myc Proto-Oncogene Protein
    Language English
    Publishing date 2020-09-15
    Publishing country United States
    Document type Journal Article ; Systematic Review
    ZDB-ID 1065043-x
    ISSN 1439-359X ; 0939-7248 ; 0939-6764 ; 0930-7249
    ISSN (online) 1439-359X
    ISSN 0939-7248 ; 0939-6764 ; 0930-7249
    DOI 10.1055/s-0040-1716836
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    Zs.A 3140: Show issues Location:
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  9. Article ; Online: Neuroblastoma: the association of anatomical tumour site, molecular biology and patient outcomes.

    Salim, Adeline / Raitio, Arimatias / Pizer, Barry / Mullassery, Dhanya / Losty, Paul D

    ANZ journal of surgery

    2021  Volume 91, Issue 5, Page(s) 1000–1004

    Abstract: Background: Numerous factors have been identified as carrying prognostic value in neuroblastoma (NB) and therefore incorporated in risk stratification of disease. Here, we investigate the association of anatomical site of NB with molecular biology and ... ...

    Abstract Background: Numerous factors have been identified as carrying prognostic value in neuroblastoma (NB) and therefore incorporated in risk stratification of disease. Here, we investigate the association of anatomical site of NB with molecular biology and clinical outcomes.
    Methods: A total of 117 patients with NB were studied over a 30-year period. Tumour location was confirmed with computed tomography/magnetic resonance imaging. Data on molecular biology were obtained as testing became available. Chi-squared, Fisher's exact test and Kaplan-Meier log-rank tests were used for statistical analysis.
    Results: Tumour originated in the thoracic region (thoracic NB, TNB) in 15 patients (13%), adrenal gland (adrenal NB, ANB) in 88 patients (75%) and abdominal/paravertebral chain (paravertebral NB, PVNB) in 14 patients (12%). Overall survival (OS) for ANB was significantly lower (38%; P = 0.015). ANB cases were more frequently diagnosed at stage IV (69%; P = 0.001). MYCN amplification was noted in 33% of ANB cases and associated with lower OS (17% versus 62% MYCN non-amplified ANB; P = 0.01). The vast majority of TNB and PVNB were non-MYCN amplified (100% and 86%, respectively) and carried better prognosis (OS 86% and 83%, respectively). Forty-two percent of ANB cases were diploid and had lower OS (20% versus 71% hyperdiploid ANB; P = 0.079). TNB and PVNB were found to be mostly hyperdiploid (86% and 100%, respectively) with better OS (83% and 33%, respectively). Segmental chromosomal alterations had prognostic significance in those with PVNB (P = 0.03).
    Conclusion: TNB tumours have better outcomes than adrenal tumours. This may be due to varied factors reported here including non-metastatic disease at presentation, non-amplification of the MYCN oncogene and overall favourable molecular biology characteristics.
    MeSH term(s) Humans ; Infant ; Kaplan-Meier Estimate ; Molecular Biology ; N-Myc Proto-Oncogene Protein/genetics ; Neuroblastoma/diagnostic imaging ; Neuroblastoma/genetics ; Prognosis
    Chemical Substances N-Myc Proto-Oncogene Protein
    Language English
    Publishing date 2021-01-28
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 2050749-5
    ISSN 1445-2197 ; 1445-1433 ; 0004-8682
    ISSN (online) 1445-2197
    ISSN 1445-1433 ; 0004-8682
    DOI 10.1111/ans.16595
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  10. Article ; Online: Pd

    Breitwieser, Kevin / Bevilacqua, Matteo / Mullassery, Sneha / Dankert, Fabian / Morgenstern, Bernd / Grandthyll, Samuel / Müller, Frank / Biffis, Andrea / Hering-Junghans, Christian / Munz, Dominik

    Advanced science (Weinheim, Baden-Wurttemberg, Germany)

    2024  , Page(s) e2400699

    Abstract: Atomically precise nanoclusters hold promise for supramolecular assembly and (opto)electronic- as well as magnetic materials. Herein, this work reports that treating palladium(0) precursors with a triphosphirane affords strongly colored ... ...

    Abstract Atomically precise nanoclusters hold promise for supramolecular assembly and (opto)electronic- as well as magnetic materials. Herein, this work reports that treating palladium(0) precursors with a triphosphirane affords strongly colored Pd
    Language English
    Publishing date 2024-04-18
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2808093-2
    ISSN 2198-3844 ; 2198-3844
    ISSN (online) 2198-3844
    ISSN 2198-3844
    DOI 10.1002/advs.202400699
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