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  1. Article ; Online: Transcatheter aortic valve implantation for pure aortic insufficiency in a patient following David-type aortic valve-sparing root replacement after aortic dissection-A successful off-label procedure.

    Oztas, Didem Melis / Ozdemir, Emrah / Bauernschmitt, Robert / Ugurlucan, Murat

    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions

    2024  Volume 103, Issue 6, Page(s) 1074–1077

    Abstract: Transcatheter aortic valve implantation (TAVI) has traditionally been indicated for the treatment of aortic stenosis. However, in this case report, we describe a successful TAVI procedure in a 46-year-old male patient who had previously undergone David ... ...

    Abstract Transcatheter aortic valve implantation (TAVI) has traditionally been indicated for the treatment of aortic stenosis. However, in this case report, we describe a successful TAVI procedure in a 46-year-old male patient who had previously undergone David aortic valve-sparing aortic root replacement for type 1 aortic dissection. The patient presented with aortic valve insufficiency 4 years after the initial surgery and was subsequently treated with a 34 mm Medtronic CoreValve Evolut R prosthesis via TAVI. This case highlights the feasibility of TAVI as a viable treatment option for postoperative aortic valve insufficiency in patients with prior ascending aortic or aortic arch surgery.
    MeSH term(s) Humans ; Male ; Aortic Dissection/surgery ; Aortic Dissection/diagnostic imaging ; Aortic Valve Insufficiency/diagnostic imaging ; Aortic Valve Insufficiency/etiology ; Aortic Valve Insufficiency/surgery ; Aortic Valve Insufficiency/physiopathology ; Middle Aged ; Transcatheter Aortic Valve Replacement/adverse effects ; Transcatheter Aortic Valve Replacement/instrumentation ; Treatment Outcome ; Heart Valve Prosthesis ; Blood Vessel Prosthesis Implantation/instrumentation ; Blood Vessel Prosthesis Implantation/adverse effects ; Aortic Valve/surgery ; Aortic Valve/diagnostic imaging ; Aortic Valve/physiopathology ; Prosthesis Design ; Blood Vessel Prosthesis ; Aortic Aneurysm, Thoracic/surgery ; Aortic Aneurysm, Thoracic/diagnostic imaging ; Aortic Aneurysm/surgery ; Aortic Aneurysm/diagnostic imaging ; Aortography
    Language English
    Publishing date 2024-04-05
    Publishing country United States
    Document type Case Reports
    ZDB-ID 1459995-8
    ISSN 1522-726X ; 1522-1946
    ISSN (online) 1522-726X
    ISSN 1522-1946
    DOI 10.1002/ccd.31033
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    Zs.A 1226: Show issues Location:
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  2. Article: Nutzen altersmedizinischer Abklärungen vor Operationen, Interventionen und onkologischen Therapien.

    Gagesch, Michael / Rösler, Wiebke / Bauernschmitt, Robert / Wilhelm, Markus J / Freystätter, Gregor

    Praxis

    2023  Volume 112, Issue 5-6, Page(s) 340–347

    Abstract: Benefit of a Geriatric Evaluation before Operations, Interventions and Oncological ... ...

    Title translation Benefit of a Geriatric Evaluation before Operations, Interventions and Oncological Therapies.
    Abstract Benefit of a Geriatric Evaluation before Operations, Interventions and Oncological Therapies
    MeSH term(s) Humans ; Aged ; Geriatric Assessment/methods ; Treatment Outcome
    Language German
    Publishing date 2023-03-31
    Publishing country Switzerland
    Document type English Abstract ; Journal Article
    ZDB-ID 209026-0
    ISSN 1661-8165 ; 1661-8157 ; 0369-8394
    ISSN (online) 1661-8165
    ISSN 1661-8157 ; 0369-8394
    DOI 10.1024/1661-8157/a004050
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  3. Book ; Thesis: Untersuchungen zum Einfluß der Ovariektomie auf die Inflammations-mediierte Osteopenie bei der Ratte

    Bauernschmitt, Robert

    1990  

    Author's details vorgelegt von Robert Bauernschmitt
    Size 100 Bl. : Ill., graph. Darst.
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Heidelberg, Univ., Diss., 1990
    HBZ-ID HT003829541
    Database Catalogue ZB MED Medicine, Health

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    91 E 2392 order for loan Magazin

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  4. Article ; Online: Does Comprehensive Geriatric Assessment Reduce the Incidence of Postoperative Delirium? A Quasi-experimental Study in Older Adults Undergoing Transcatheter Aortic Valve Implantation.

    Schwesinger, Anna / Tsai, Li-Tang / Lang, Wei / Mantegazza, Noemi / Bauernschmitt, Robert / Wilhelm, Markus Johannes / Bischoff-Ferrari, Heike Annette / Gagesch, Michael

    Clinical interventions in aging

    2024  Volume 19, Page(s) 347–355

    Abstract: Purpose: Postoperative delirium (POD) after transcatheter aortic valve implantation (TAVI) is frequent in older adults and associated with multiple negative outcomes including a higher mortality. We aimed to investigate whether a comprehensive geriatric ...

    Abstract Purpose: Postoperative delirium (POD) after transcatheter aortic valve implantation (TAVI) is frequent in older adults and associated with multiple negative outcomes including a higher mortality. We aimed to investigate whether a comprehensive geriatric assessment (CGA) prior to TAVI reduces the odds of POD and results in a positive change in self-care ability, intended to lay a foundation for future geriatric comanagement.
    Patients and methods: We used a retrospective, single-center study with a quasi-experimental design enrolling patients aged 70 years and older undergoing CGA before elective TAVI, and a nonrandomized comparison group without preoperative CGA. Data on POD occurrence during the first 5 days after TAVI (primary outcome) and change in self-care ability index (SPI) between admission and discharge (secondary outcome) were collected from electronic health records and CGA data (exposure) by clinical assessment. To explore associations between (1) CGA and POD, and (2) CGA and SPI, multivariate logistic regression and linear regression models were applied adjusting for age, sex, BMI, and number of medications.
    Results: Among 435 patients (mean age 81.0 ± 5.6 years, 43.6% women, median [IQR] SPI at baseline 40 [39, 40] points), POD incidence was 14.3% in the CGA group vs 18.8% in the non-CGA group (
    Conclusion: We observed no association of CGA prior to TAVI with POD incidence or postoperative self-care, highlighting the need for additional studies investigating the effect of POD preventive measures in older TAVI patients integrated into a comprehensive geriatric comanagement program.
    MeSH term(s) Humans ; Female ; Aged ; Aged, 80 and over ; Male ; Emergence Delirium ; Geriatric Assessment ; Incidence ; Retrospective Studies ; Transcatheter Aortic Valve Replacement/adverse effects
    Language English
    Publishing date 2024-02-28
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2364924-0
    ISSN 1178-1998 ; 1176-9092
    ISSN (online) 1178-1998
    ISSN 1176-9092
    DOI 10.2147/CIA.S448167
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  5. Article ; Online: Interventional versus Surgical Treatment of Degenerated Freestyle Prosthesis.

    Fedorov, Denis / Bauernschmitt, Robert / Grunebaum, Jean-Pilippe / Bauer, Stefan / Sodian, Ralf / von Hodenberg, Eberhard

    The Thoracic and cardiovascular surgeon

    2023  Volume 72, Issue 3, Page(s) 188–196

    Abstract: Background:  Bioprosthetic stentless aortic valves may degenerate over time and will require replacement. This study aimed to evaluate early- and mid-term outcomes after isolated surgical redo aortic valve replacement (redo-SAVR) and transcatheter valve- ...

    Abstract Background:  Bioprosthetic stentless aortic valves may degenerate over time and will require replacement. This study aimed to evaluate early- and mid-term outcomes after isolated surgical redo aortic valve replacement (redo-SAVR) and transcatheter valve-in-valve implantation (TAVI-VIV) for degenerated stentless Freestyle bioprostheses.
    Methods:  We reviewed records of 56 patients at a single center. Overall, 37 patients (66.1%) received TAVI-VIV and 19 (33.9%) received redo-SAVR.
    Results:  Thirty-day survival was similar in both groups (100%). One-year survival was comparable between groups (97.3% in TAVI-VIV and 100% in redo-SAVR,
    Conclusion:  The 30-day and 1-year survival rates after both procedures were outstanding, irrespective of baseline characteristics. Isolated redo-SAVR should be favored in young patients, as the pacemaker implantation rate is lower. TAVI-VIV for degenerated Freestyle prosthesis can be a method of choice in elderly patients and those with high operative risk.
    MeSH term(s) Aged ; Humans ; Aortic Valve/diagnostic imaging ; Aortic Valve/surgery ; Aortic Valve Stenosis/diagnostic imaging ; Aortic Valve Stenosis/surgery ; Bioprosthesis/adverse effects ; Heart Valve Prosthesis/adverse effects ; Heart Valve Prosthesis Implantation ; Prosthesis Failure ; Reoperation/methods ; Risk Factors ; Transcatheter Aortic Valve Replacement/methods ; Treatment Outcome
    Language English
    Publishing date 2023-03-01
    Publishing country Germany
    Document type Review ; Journal Article
    ZDB-ID 800050-5
    ISSN 1439-1902 ; 0171-6425 ; 0946-4778 ; 0172-6137
    ISSN (online) 1439-1902
    ISSN 0171-6425 ; 0946-4778 ; 0172-6137
    DOI 10.1055/s-0043-1763286
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  6. Article ; Online: Invited commentary.

    Bauernschmitt, Robert

    The Annals of thoracic surgery

    2011  Volume 91, Issue 1, Page(s) 96

    MeSH term(s) Aortic Aneurysm/pathology ; Aortic Aneurysm/physiopathology ; Aortic Aneurysm/surgery ; Compliance/physiology ; Humans ; Magnetic Resonance Imaging ; Sinus of Valsalva/pathology ; Sinus of Valsalva/physiopathology ; Sinus of Valsalva/surgery ; Treatment Outcome
    Language English
    Publishing date 2011-01
    Publishing country Netherlands
    Document type Comment ; Journal Article
    ZDB-ID 211007-6
    ISSN 1552-6259 ; 0003-4975
    ISSN (online) 1552-6259
    ISSN 0003-4975
    DOI 10.1016/j.athoracsur.2010.10.045
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    Zs.A 252: Show issues Location:
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  7. Article ; Online: Valve-in-valve transcatheter aortic valve replacement in a young patient with a suspected COVID-19 infection: a surgical dilemma in the era of the COVID-19 pandemic.

    Bauernschmitt, Robert / Gabriel, Philip / Gottardi, Roman / Sodian, Ralf

    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery

    2020  Volume 58, Issue 1, Page(s) 188–189

    Abstract: We report on a case of a 57-year-old male patient, who underwent full root replacement in 2005 and now presented with high grade aortic insufficiency. On admission, the patient underwent a computed tomography scan which demonstrated interstitial ... ...

    Abstract We report on a case of a 57-year-old male patient, who underwent full root replacement in 2005 and now presented with high grade aortic insufficiency. On admission, the patient underwent a computed tomography scan which demonstrated interstitial infiltration in the left lung, highly suspicious for a COVID-19 infection that could not be confirmed by reverse transcription polymerase chain reaction (RT-PCR) testing. As there usually is a delay between infection and positive RT-PCR test results, the initial decision was to perform additional testing. However, the patient deteriorated quickly in spite of optimal medical therapy making urgent aortic valve replacement necessary. We decided to perform transcatheter aortic valve replacement to avoid cardiopulmonary bypass with shorter operative times, presumably shorter ventilation times and duration of intensive care unit stay, and thus a lesser risk for pulmonary complications.
    MeSH term(s) Aortic Valve Insufficiency/complications ; Aortic Valve Insufficiency/surgery ; Betacoronavirus/isolation & purification ; COVID-19 ; Coronavirus Infections/complications ; Coronavirus Infections/diagnosis ; Humans ; Male ; Middle Aged ; Pandemics ; Pneumonia, Viral/complications ; Pneumonia, Viral/diagnosis ; SARS-CoV-2 ; Transcatheter Aortic Valve Replacement/methods
    Keywords covid19
    Language English
    Publishing date 2020-05-26
    Publishing country Germany
    Document type Case Reports ; Journal Article
    ZDB-ID 639293-3
    ISSN 1873-734X ; 1010-7940 ; 1567-4258
    ISSN (online) 1873-734X
    ISSN 1010-7940 ; 1567-4258
    DOI 10.1093/ejcts/ezaa193
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  8. Article ; Online: Evaluation of the 2023 Duke-ISCVID and 2023 Duke-ESC Clinical Criteria for the Diagnosis of Infective Endocarditis in a Multicenter Cohort of Patients With Staphylococcus aureus Bacteremia.

    Papadimitriou-Olivgeris, Matthaios / Monney, Pierre / Frank, Michelle / Tzimas, Georgios / Tozzi, Piergiorgio / Kirsch, Matthias / Van Hemelrijck, Mathias / Bauernschmitt, Robert / Epprecht, Jana / Guery, Benoit / Hasse, Barbara

    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

    2024  Volume 78, Issue 3, Page(s) 655–662

    Abstract: Background: The Duke criteria for infective endocarditis (IE) diagnosis underwent revisions in 2023 by the European Society of Cardiology (ESC) and the International Society for Cardiovascular Infectious Diseases (ISCVID). This study aims to assess the ... ...

    Abstract Background: The Duke criteria for infective endocarditis (IE) diagnosis underwent revisions in 2023 by the European Society of Cardiology (ESC) and the International Society for Cardiovascular Infectious Diseases (ISCVID). This study aims to assess the diagnostic accuracy of these criteria, focusing on patients with Staphylococcus aureus bacteremia (SAB).
    Methods: This Swiss multicenter study conducted between 2014 and 2023 pooled data from three cohorts. It evaluated the performance of each iteration of the Duke criteria by assessing the degree of concordance between definite S. aureus IE (SAIE) and the diagnoses made by the Endocarditis Team (2018-23) or IE expert clinicians (2014-17).
    Results: Among 1344 SAB episodes analyzed, 486 (36%) were identified as cases of SAIE. The 2023 Duke-ISCVID and 2023 Duke-ESC criteria demonstrated improved sensitivity for SAIE diagnosis (81% and 82%, respectively) compared to the 2015 Duke-ESC criteria (75%). However, the new criteria exhibited reduced specificity for SAIE (96% for both) compared to the 2015 criteria (99%). Spondylodiscitis was more prevalent among patients with SAIE compared to those with SAB alone (10% vs 7%, P = .026). However, when patients meeting the minor 2015 Duke-ESC vascular criterion were excluded, the incidence of spondylodiscitis was similar between SAIE and SAB patients (6% vs 5%, P = .461).
    Conclusions: The 2023 Duke-ISCVID and 2023 Duke-ESC clinical criteria show improved sensitivity for SAIE diagnosis compared to 2015 Duke-ESC criteria. However, this increase in sensitivity comes at the expense of reduced specificity. Future research should aim at evaluating the impact of each component introduced within these criteria.
    MeSH term(s) Humans ; Staphylococcus aureus ; Discitis ; Endocarditis, Bacterial/diagnosis ; Endocarditis, Bacterial/epidemiology ; Endocarditis/diagnosis ; Staphylococcal Infections/diagnosis ; Staphylococcal Infections/epidemiology ; Bacteremia/diagnosis ; Bacteremia/epidemiology ; Cardiology
    Language English
    Publishing date 2024-01-02
    Publishing country United States
    Document type Multicenter Study ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1099781-7
    ISSN 1537-6591 ; 1058-4838
    ISSN (online) 1537-6591
    ISSN 1058-4838
    DOI 10.1093/cid/ciae003
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    Zs.A 1505: Show issues Location:
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    Zs.MO 480: Show issues

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  9. Article ; Online: Evaluation of the 2023 Duke-International Society of Cardiovascular Infectious Diseases Criteria in a Multicenter Cohort of Patients With Suspected Infective Endocarditis.

    Papadimitriou-Olivgeris, Matthaios / Monney, Pierre / Frank, Michelle / Tzimas, Georgios / Tozzi, Piergiorgio / Kirsch, Matthias / Van Hemelrijck, Mathias / Bauernschmitt, Robert / Epprecht, Jana / Guery, Benoit / Hasse, Barbara

    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

    2024  Volume 78, Issue 4, Page(s) 949–955

    Abstract: Background: Since publication of Duke criteria for infective endocarditis (IE) diagnosis, several modifications have been proposed. We aimed to evaluate the diagnostic performance of the Duke-ISCVID (International Society of Cardiovascular Infectious ... ...

    Abstract Background: Since publication of Duke criteria for infective endocarditis (IE) diagnosis, several modifications have been proposed. We aimed to evaluate the diagnostic performance of the Duke-ISCVID (International Society of Cardiovascular Infectious Diseases) 2023 criteria compared to prior versions from 2000 (Duke-Li 2000) and 2015 (Duke-ESC [European Society for Cardiology] 2015).
    Methods: This study was conducted at 2 university hospitals between 2014 and 2022 among patients with suspected IE. A case was classified as IE (final IE diagnosis) by the Endocarditis Team. Sensitivity for each version of the Duke criteria was calculated among patients with confirmed IE based on pathological, surgical, and microbiological data. Specificity for each version of the Duke criteria was calculated among patients with suspected IE for whom IE diagnosis was ruled out.
    Results: In total, 2132 episodes with suspected IE were included, of which 1101 (52%) had final IE diagnosis. Definite IE by pathologic criteria was found in 285 (13%), 285 (13%), and 345 (16%) patients using the Duke-Li 2000, Duke-ESC 2015, or the Duke-ISCVID 2023 criteria, respectively. IE was excluded by histopathology in 25 (1%) patients. The Duke-ISCVID 2023 clinical criteria showed a higher sensitivity (84%) compared to previous versions (70%). However, specificity of the new clinical criteria was lower (60%) compared to previous versions (74%).
    Conclusions: The Duke-ISCVID 2023 criteria led to an increase in sensitivity compared to previous versions. Further studies are needed to evaluate items that could increase sensitivity by reducing the number of IE patients misclassified as possible, but without having detrimental effect on specificity of Duke criteria.
    MeSH term(s) Humans ; Endocarditis, Bacterial/diagnosis ; Endocarditis/diagnosis ; Heart Valve Prosthesis/microbiology ; Communicable Diseases ; Fluorodeoxyglucose F18
    Chemical Substances Fluorodeoxyglucose F18 (0Z5B2CJX4D)
    Language English
    Publishing date 2024-02-06
    Publishing country United States
    Document type Multicenter Study ; Journal Article
    ZDB-ID 1099781-7
    ISSN 1537-6591 ; 1058-4838
    ISSN (online) 1537-6591
    ISSN 1058-4838
    DOI 10.1093/cid/ciae039
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  10. Article: Interventional versus Surgical Treatment of Degenerated Freestyle Prosthesis

    Fedorov, Denis / Bauernschmitt, Robert / Grunebaum, Jean-Pilippe / Bauer, Stefan / Sodian, Ralf / von Hodenberg, Eberhard

    The Thoracic and Cardiovascular Surgeon

    2023  Volume 72, Issue 03, Page(s) 188–196

    Abstract: Background: Bioprosthetic stentless aortic valves may degenerate over time and will require replacement. This study aimed to evaluate early- and mid-term outcomes after isolated surgical redo aortic valve replacement (redo-SAVR) and transcatheter valve- ... ...

    Abstract Background: Bioprosthetic stentless aortic valves may degenerate over time and will require replacement. This study aimed to evaluate early- and mid-term outcomes after isolated surgical redo aortic valve replacement (redo-SAVR) and transcatheter valve-in-valve implantation (TAVI-VIV) for degenerated stentless Freestyle bioprostheses.
    Methods: We reviewed records of 56 patients at a single center. Overall, 37 patients (66.1%) received TAVI-VIV and 19 (33.9%) received redo-SAVR.
    Results: Thirty-day survival was similar in both groups (100%). One-year survival was comparable between groups (97.3% in TAVI-VIV and 100% in redo-SAVR, p  = 1.0). The difference in mid-term survival after adjusting for age and EuroScore II was not significant ( p  = 0.41). The incidence of pacemaker implantation after TAVI-VIV was higher than after redo-SAVR (19.4% vs. 0%, p  = 0.08).
    Conclusion: The 30-day and 1-year survival rates after both procedures were outstanding, irrespective of baseline characteristics. Isolated redo-SAVR should be favored in young patients, as the pacemaker implantation rate is lower. TAVI-VIV for degenerated Freestyle prosthesis can be a method of choice in elderly patients and those with high operative risk.
    Keywords xenograft ; reoperation ; heart valve ; percutaneous (TAVI) ; heart valve surgery ; aortic valve and root
    Language English
    Publishing date 2023-03-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 800050-5
    ISSN 1439-1902 ; 0171-6425 ; 0946-4778 ; 0172-6137
    ISSN (online) 1439-1902
    ISSN 0171-6425 ; 0946-4778 ; 0172-6137
    DOI 10.1055/s-0043-1763286
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