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  1. Article ; Online: Single photon emitter deterministically coupled to a topological corner state.

    Rao, Mujie / Shi, Fulong / Rao, Zhixuan / Yang, Jiawei / Song, Changkun / Chen, Xiaodong / Dong, Jianwen / Yu, Ying / Yu, Siyuan

    Light, science & applications

    2024  Volume 13, Issue 1, Page(s) 19

    Abstract: Incorporating topological physics into the realm of quantum photonics holds the promise of developing quantum light emitters with inherent topological robustness and immunity to backscattering. Nonetheless, the deterministic interaction of quantum ... ...

    Abstract Incorporating topological physics into the realm of quantum photonics holds the promise of developing quantum light emitters with inherent topological robustness and immunity to backscattering. Nonetheless, the deterministic interaction of quantum emitters with topologically nontrivial resonances remains largely unexplored. Here we present a single photon emitter that utilizes a single semiconductor quantum dot, deterministically coupled to a second-order topological corner state in a photonic crystal cavity. By investigating the Purcell enhancement of both single photon count and emission rate within this topological cavity, we achieve an experimental Purcell factor of F
    Language English
    Publishing date 2024-01-17
    Publishing country England
    Document type Journal Article
    ZDB-ID 2662628-7
    ISSN 2047-7538 ; 2047-7538
    ISSN (online) 2047-7538
    ISSN 2047-7538
    DOI 10.1038/s41377-024-01377-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Effects of different types of xanthophyll extracted from marigold on pigmentation of yellow-feathered chickens

    Yu Wei / Kun Qin / Xu Qin / Fulong Song / Xiao Xu

    Animal Bioscience, Vol 36, Iss 12, Pp 1853-

    2023  Volume 1859

    Abstract: Objective This study aimed to explore the effects of different types of xanthophyll extracted from marigold on the growth performance, skin color, and carcass pigmentation. Methods A total of 192 healthy 60-day-old yellow-feathered broilers weighing an ... ...

    Abstract Objective This study aimed to explore the effects of different types of xanthophyll extracted from marigold on the growth performance, skin color, and carcass pigmentation. Methods A total of 192 healthy 60-day-old yellow-feathered broilers weighing an average of 1,279±81 g were randomly allocated to 4 groups, each with 6 replicates and 8 broilers. The 4 treatments were as follows: i) CON group, fed with basal diet; ii) LTN group, supplemented with lutein; iii) MDP group, supplemented with monohydroxyl pigment including dehydrated lutein, β-cryptoxanthin, and α-cryptoxanthin; iv) LTN+MDP group, supplemented with lutein and monohydroxyl pigment in proportion to 1:1. The supplementary content of LTN, MDP, and LTN+MDP was 2 g/kg. Skin color was measured after 7, 14, 21, and 28 days of feeding the dietary treatments. The breast, thigh, and abdominal fat of slaughtered chickens were stored in cold storage at 4°C for 24 hours and then the meat color of lightness (L*), redness (a*), and yellowness (b*) values was determined. Results The results showed that all treatments enhanced the yellow scores of subwing skin on day 14, 21, and 28 (p<0.05), and the mixture of lutein and monohydroxyl pigment promoted the yellow scores of shanks on day 14, 21, and 28 (p<0.05). The mixture of lutein and monohydroxyl pigment increased the yellow scores of beaks and all treatments enhanced the yellow of shanks on day 28 (p<0.05). In addition, all treatments improved the yellow (b*) values of breast and thigh muscle, moreover, the monohydroxyl pigment and the mixture of lutein and monohydroxyl pigment enhanced the values of redness (a*) and yellow (b*) of abdominal fat (p<0.05). Conclusion In summary, different types of xanthophyll extracted from marigold significantly increased the yellow scores of skin color and the yellow (b*) values of carcass pigmentation. Especially, the mixture of lutein and monohydroxyl pigment was more efficient on skin color.
    Keywords marigold ; monohydroxyl pigment ; pigmentation ; xanthophyll ; yellow-feathered chicken ; Zoology ; QL1-991
    Subject code 571
    Language English
    Publishing date 2023-12-01T00:00:00Z
    Publisher Asian-Australasian Association of Animal Production Societies
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article: Design, synthesis, and evaluation of the novel ozagrel-paeonol codrug with antiplatelet aggregation activities as a potent anti-stroke therapeutic agent.

    Zuo, Chijing / Yan, Fulong / Wang, Jie / Zhu, Yulong / Luo, Wenhui / Liu, Yan / Liang, Wanhui / Yu, Weidong / Zhang, Jingwei / Peng, Daiyin / Ma, Xiaodong / Peng, Can

    Frontiers in pharmacology

    2024  Volume 15, Page(s) 1362857

    Abstract: Introduction: ...

    Abstract Introduction:
    Language English
    Publishing date 2024-03-19
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2024.1362857
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: HCMV-IE2 promotes atherosclerosis by inhibiting vascular smooth muscle cells' pyroptosis.

    Ma, Guixin / Yu, Zhongjie / Nan, Fulong / Zhang, Xianjuan / Jiang, Shasha / Wang, Yunyang / Wang, Bin

    Frontiers in microbiology

    2023  Volume 14, Page(s) 1177391

    Abstract: Atherosclerosis is still the main cause of death in developed and developing countries. Vascular smooth muscle cells (VSMCs) death disorder is a key pathogens of atherosclerosis. During the early stage of human cytomegalovirus (HCMV) infection, immediate ...

    Abstract Atherosclerosis is still the main cause of death in developed and developing countries. Vascular smooth muscle cells (VSMCs) death disorder is a key pathogens of atherosclerosis. During the early stage of human cytomegalovirus (HCMV) infection, immediate early protein 2 (IE2) is critical in regulating its host cell death to ensure HCMV replication. Abnormal cell death induced by HCMV infection contributes to the development of numerous diseases, including atherosclerosis. Hitherto, the underlying mechanism of HCMV involved in the progression of atherosclerosis is still unclear. In this study, the infection models
    Language English
    Publishing date 2023-05-10
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587354-4
    ISSN 1664-302X
    ISSN 1664-302X
    DOI 10.3389/fmicb.2023.1177391
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  5. Article: Effects of different types of xanthophyll extracted from marigold on pigmentation of yellow-feathered chickens.

    Wei, Yu / Qin, Kun / Qin, Xu / Song, Fulong / Xu, Xiao

    Animal bioscience

    2023  Volume 36, Issue 12, Page(s) 1853–1859

    Abstract: Objective: This study aimed to explore the effects of different types of xanthophyll extracted from marigold on the growth performance, skin color, and carcass pigmentation.: Methods: A total of 192 healthy 60-day-old yellow-feathered broilers ... ...

    Abstract Objective: This study aimed to explore the effects of different types of xanthophyll extracted from marigold on the growth performance, skin color, and carcass pigmentation.
    Methods: A total of 192 healthy 60-day-old yellow-feathered broilers weighing an average of 1,279±81 g were randomly allocated to 4 groups, each with 6 replicates and 8 broilers. The 4 treatments were as follows: i) CON group, fed with basal diet; ii) LTN group, supplemented with lutein; iii) MDP group, supplemented with monohydroxyl pigment including dehydrated lutein, β-cryptoxanthin, and α-cryptoxanthin; iv) LTN+MDP group, supplemented with lutein and monohydroxyl pigment in proportion to 1:1. The supplementary content of LTN, MDP, and LTN+MDP was 2 g/kg. Skin color was measured after 7, 14, 21, and 28 days of feeding the dietary treatments. The breast, thigh, and abdominal fat of slaughtered chickens were stored in cold storage at 4°C for 24 hours and then the meat color of lightness (L*), redness (a*), and yellowness (b*) values was determined.
    Results: The results showed that all treatments enhanced the yellow scores of subwing skin on day 14, 21, and 28 (p<0.05), and the mixture of lutein and monohydroxyl pigment promoted the yellow scores of shanks on day 14, 21, and 28 (p<0.05). The mixture of lutein and monohydroxyl pigment increased the yellow scores of beaks and all treatments enhanced the yellow of shanks on day 28 (p<0.05). In addition, all treatments improved the yellow (b*) values of breast and thigh muscle, moreover, the monohydroxyl pigment and the mixture of lutein and monohydroxyl pigment enhanced the values of redness (a*) and yellow (b*) of abdominal fat (p<0.05).
    Conclusion: In summary, different types of xanthophyll extracted from marigold significantly increased the yellow scores of skin color and the yellow (b*) values of carcass pigmentation. Especially, the mixture of lutein and monohydroxyl pigment was more efficient on skin color.
    Language English
    Publishing date 2023-06-26
    Publishing country Korea (South)
    Document type Journal Article
    ISSN 2765-0189
    ISSN 2765-0189
    DOI 10.5713/ab.23.0097
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: CUT&RUNTools 2.0: a pipeline for single-cell and bulk-level CUT&RUN and CUT&Tag data analysis.

    Yu, Fulong / Sankaran, Vijay G / Yuan, Guo-Cheng

    Bioinformatics (Oxford, England)

    2021  Volume 38, Issue 1, Page(s) 252–254

    Abstract: ... yu/CUT-RUNTools-2.0.: Supplementary information: Supplementary data are available ...

    Abstract Motivation: Genome-wide profiling of transcription factor binding and chromatin states is a widely-used approach for mechanistic understanding of gene regulation. Recent technology development has enabled such profiling at single-cell resolution. However, an end-to-end computational pipeline for analyzing such data is still lacking.
    Results: Here, we have developed a flexible pipeline for analysis and visualization of single-cell CUT&Tag and CUT&RUN data, which provides functions for sequence alignment, quality control, dimensionality reduction, cell clustering, data aggregation and visualization. Furthermore, it is also seamlessly integrated with the functions in original CUT&RUNTools for population-level analyses. As such, this provides a valuable toolbox for the community.
    Availability and implementation: https://github.com/fl-yu/CUT-RUNTools-2.0.
    Supplementary information: Supplementary data are available at Bioinformatics online.
    MeSH term(s) Software ; Chromatin ; Sequence Alignment ; Single-Cell Analysis
    Chemical Substances Chromatin
    Language English
    Publishing date 2021-07-02
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 1422668-6
    ISSN 1367-4811 ; 1367-4803
    ISSN (online) 1367-4811
    ISSN 1367-4803
    DOI 10.1093/bioinformatics/btab507
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  7. Article ; Online: Phenotypic Variation in Flower Color and Morphology in the Gerbera (

    Zhou, Yiwei / Zou, Xinru / Yan, Fulong / He, Jingjuan / Zeng, Sixian / Yu, Yunyi / Tang, Xiaoshuang / Liang, Xuanguo / Cai, Xiuping / Yu, Rangcai / Fan, Yanping

    International journal of molecular sciences

    2023  Volume 25, Issue 1

    Abstract: Gerbera ( ...

    Abstract Gerbera (
    MeSH term(s) Animals ; Plant Breeding ; Asteraceae ; Flowers/genetics ; Gastropoda ; Biological Variation, Population
    Language English
    Publishing date 2023-12-22
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms25010203
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  8. Article ; Online: Coupling Ultrafine Pt Nanocrystals over the Fe

    Wang, Fulong / Fang, Bo / Yu, Xu / Feng, Ligang

    ACS applied materials & interfaces

    2019  Volume 11, Issue 9, Page(s) 9496–9503

    Abstract: Ultrafine Pt nanocrystals with an average particle size of 2.2 ± 1 nm coupled over the petaloid ... ...

    Abstract Ultrafine Pt nanocrystals with an average particle size of 2.2 ± 1 nm coupled over the petaloid Fe
    Language English
    Publishing date 2019-02-21
    Publishing country United States
    Document type Journal Article
    ISSN 1944-8252
    ISSN (online) 1944-8252
    DOI 10.1021/acsami.8b18029
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Human Cytomegalovirus Induced Aberrant Expression of Non-coding RNAs.

    Yu, Zhongjie / Wang, Jing / Nan, Fulong / Shi, Wenyi / Zhang, Xianjuan / Jiang, Shasha / Wang, Bin

    Frontiers in microbiology

    2022  Volume 13, Page(s) 918213

    Abstract: Human cytomegalovirus (HCMV) is a β-herpesvirus whose genome consists of double stranded linear DNA. HCMV genome can generate non-coding RNAs (ncRNAs) through transcription in its host cells. Besides that, HCMV infection also changes the ncRNAs ... ...

    Abstract Human cytomegalovirus (HCMV) is a β-herpesvirus whose genome consists of double stranded linear DNA. HCMV genome can generate non-coding RNAs (ncRNAs) through transcription in its host cells. Besides that, HCMV infection also changes the ncRNAs expression profile of the host cells. ncRNAs play a key role in maintaining the normal physiological activity of cells, and the disorder of ncRNAs expression has numerous adverse effects on cells. However, until now, the relationship between ncRNAs and HCMV-induced adverse effects are not summarized in detail. This review aims to give a systematic summary of the role of HCMV infection in ncRNAs expression while providing insights into the molecular mechanism of unnormal cellular events caused by ncRNAs disorder. ncRNAs disorder induced by HCMV infection is highly associated with cell proliferation, apoptosis, tumorigenesis, and immune regulation, as well as the development of cardiovascular diseases, and the potential role of biomarker. We summarize the studies on HCMV associated ncRNAs disorder and suggest innovative strategies for eliminating the adverse effects caused by HCMV infection.
    Language English
    Publishing date 2022-06-13
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2587354-4
    ISSN 1664-302X
    ISSN 1664-302X
    DOI 10.3389/fmicb.2022.918213
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Heuristic Routing Algorithms for Time-Sensitive Networks in Smart Factories.

    Li, Yue / Yin, Zhenyu / Ma, Yue / Xu, Fulong / Yu, Haoyu / Han, Guangjie / Bi, Yuanguo

    Sensors (Basel, Switzerland)

    2022  Volume 22, Issue 11

    Abstract: Over recent years, traditional manufacturing factories have been accelerating their transformation and upgrade toward smart factories, which are an important concept within Industry 4.0. As a key communication technology in the industrial internet ... ...

    Abstract Over recent years, traditional manufacturing factories have been accelerating their transformation and upgrade toward smart factories, which are an important concept within Industry 4.0. As a key communication technology in the industrial internet architecture, time-sensitive networks (TSNs) can break through communication barriers between subsystems within smart factories and form a common network for various network flows. Traditional routing algorithms are not applicable for this novel type of network, as they cause unnecessary congestion and latency. Therefore, this study examined the classification of TSN flows in smart factories, converted the routing problem into two graphical problems, and proposed two heuristic optimization algorithms, namely GATTRP and AACO, to find the optimal solution. The experiments showed that the algorithms proposed in this paper could provide a more reasonable routing arrangement for various TSN flows with different time sensitivities. The algorithms could effectively reduce the overall delay by up to 74% and 41%, respectively, with promising operating performances.
    Language English
    Publishing date 2022-05-30
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s22114153
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