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  1. Article ; Online: Selpercatinib and Pseudo-Decreases in Kidney Function.

    Izzedine, Hassan / Bouderlique, Elise / Besse, Benjamin

    The New England journal of medicine

    2024  Volume 390, Issue 13, Page(s) 1241–1243

    MeSH term(s) Humans ; Pyrazoles ; Pyridines ; Urinary Tract Physiological Phenomena ; Kidney ; Lung Neoplasms ; Protein Kinase Inhibitors
    Chemical Substances selpercatinib (CEGM9YBNGD) ; Pyrazoles ; Pyridines ; Protein Kinase Inhibitors
    Language English
    Publishing date 2024-04-10
    Publishing country United States
    Document type Letter
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMc2400216
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Toxicités rénales des thérapies ciblées en oncologie.

    Izzedine, Hassan

    Nephrologie & therapeutique

    2019  Volume 16, Issue 1, Page(s) 1–8

    Abstract: The advent of new molecules oncology including targeted therapies, has resulted in improved patient survival over standard chemotherapy. The renal toxicities of these anticancer agents are more and more recognized and vary according to the targeted ... ...

    Title translation Renal toxicities of targeted therapies in oncology.
    Abstract The advent of new molecules oncology including targeted therapies, has resulted in improved patient survival over standard chemotherapy. The renal toxicities of these anticancer agents are more and more recognized and vary according to the targeted therapeutic target. This article reviews the renal toxicity associated with targeted anticancer therapies directed against Epidermal growth factor receptor, Human epidermal growth factor-2, B-rapidly accelerated fibrosarcoma, Mitogen-activated protein kinase, Anaplastic lymphoma kinase, Programmed cell death-1/programmed cell death ligand-1, Cytotoxic T lymphocyte antigen-4 and Vascular endothelial growth factor/receptor. The early diagnosis and management of these renal adverse events is essential for the clinician who cares for such patients.
    MeSH term(s) ErbB Receptors/antagonists & inhibitors ; Humans ; Kidney Diseases/chemically induced ; Molecular Targeted Therapy/adverse effects ; Neoplasms/drug therapy ; Receptor, ErbB-2/antagonists & inhibitors
    Chemical Substances EGFR protein, human (EC 2.7.10.1) ; ErbB Receptors (EC 2.7.10.1) ; Receptor, ErbB-2 (EC 2.7.10.1)
    Language French
    Publishing date 2019-12-06
    Publishing country France
    Document type Journal Article ; Review
    ZDB-ID 2229575-6
    ISSN 1872-9177 ; 1769-7255
    ISSN (online) 1872-9177
    ISSN 1769-7255
    DOI 10.1016/j.nephro.2019.06.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6298: Show issues Location:
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  3. Article ; Online: Crystal-storing lymphocytosis.

    Izzedine, Hassan / Touchard, Guy / Ghez, David

    American journal of hematology

    2023  Volume 99, Issue 1, Page(s) 142–143

    MeSH term(s) Humans ; Lymphocytosis/diagnosis ; Diagnosis, Differential
    Language English
    Publishing date 2023-05-10
    Publishing country United States
    Document type Case Reports
    ZDB-ID 196767-8
    ISSN 1096-8652 ; 0361-8609
    ISSN (online) 1096-8652
    ISSN 0361-8609
    DOI 10.1002/ajh.26947
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    Zs.A 1251: Show issues Location:
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  4. Article ; Online: How I Treat: An Algorithmic Approach to Crystalline Nephropathies: An Algorithmic Approach to Crystalline Nephropathies.

    Brocheriou, Isabelle / Jhaveri, Kenar D / Izzedine, Hassan

    Clinical journal of the American Society of Nephrology : CJASN

    2023  Volume 18, Issue 10, Page(s) 1369–1371

    MeSH term(s) Humans ; Kidney Diseases/diagnosis ; Kidney Diseases/therapy ; Algorithms
    Language English
    Publishing date 2023-06-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2226665-3
    ISSN 1555-905X ; 1555-9041
    ISSN (online) 1555-905X
    ISSN 1555-9041
    DOI 10.2215/CJN.0000000000000236
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  5. Article ; Online: Néphrotoxicité médicamenteuse.

    Izzedine, Hassan

    Nephrologie & therapeutique

    2018  Volume 14, Issue 3, Page(s) 127–134

    Abstract: Drug-induced nephrotoxicity (DIN) remains a current problem with economic and medical consequences. It affects all nephron segments. Recovery of renal function is based on the identification of risk factors, early diagnosis of renal disease, rapid (if ... ...

    Title translation Drug nephrotoxicity.
    Abstract Drug-induced nephrotoxicity (DIN) remains a current problem with economic and medical consequences. It affects all nephron segments. Recovery of renal function is based on the identification of risk factors, early diagnosis of renal disease, rapid (if possible) cessation of the causative agent and, in some cases, adjunctive therapy. Prevention is based on identification of early markers of DIN, correction of risk factors, initial assessment of renal function for adequate dosage adjustment and exclusion of other nephrotoxic factors. It has recently been proposed to standardize the phenotype of iatrogenic renal disease and, on the other hand, new markers of renal toxicity allowing early diagnosis and therefore better management of nephrotoxicity.
    MeSH term(s) Biomarkers/blood ; Early Diagnosis ; Humans ; Iatrogenic Disease ; Kidney/drug effects ; Kidney/pathology ; Kidney Diseases/chemically induced ; Kidney Diseases/diagnosis ; Phenotype ; Risk Factors
    Chemical Substances Biomarkers
    Language French
    Publishing date 2018-03-11
    Publishing country France
    Document type Journal Article ; Review
    ZDB-ID 2229575-6
    ISSN 1872-9177 ; 1769-7255
    ISSN (online) 1872-9177
    ISSN 1769-7255
    DOI 10.1016/j.nephro.2017.06.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Anaplastic lymphoma kinase inhibitors and their effect on the kidney.

    Bonilla, Marco / Jhaveri, Kenar D / Izzedine, Hassan

    Clinical kidney journal

    2022  Volume 15, Issue 8, Page(s) 1475–1482

    Abstract: Lung cancer is the leading cause of cancer-related mortality and approximately 5% of non-small-cell lung cancer (NSCLC) patients are positive for anaplastic lymphoma kinase ( ...

    Abstract Lung cancer is the leading cause of cancer-related mortality and approximately 5% of non-small-cell lung cancer (NSCLC) patients are positive for anaplastic lymphoma kinase (
    Language English
    Publishing date 2022-02-26
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2655800-2
    ISSN 2048-8513 ; 2048-8505
    ISSN (online) 2048-8513
    ISSN 2048-8505
    DOI 10.1093/ckj/sfac062
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6587: Show issues Location:
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  7. Article ; Online: How I Manage Hypertension and Proteinuria Associated with VEGF Inhibitor.

    Rashidi, Arash / Wanchoo, Rimda / Izzedine, Hassan

    Clinical journal of the American Society of Nephrology : CJASN

    2022  Volume 18, Issue 1, Page(s) 121–123

    MeSH term(s) Humans ; Vascular Endothelial Growth Factor A/therapeutic use ; Angiogenesis Inhibitors/adverse effects ; Hypertension/drug therapy ; Proteinuria/chemically induced ; Proteinuria/drug therapy
    Chemical Substances Vascular Endothelial Growth Factor A ; Angiogenesis Inhibitors
    Language English
    Publishing date 2022-08-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2226665-3
    ISSN 1555-905X ; 1555-9041
    ISSN (online) 1555-905X
    ISSN 1555-9041
    DOI 10.2215/CJN.05610522
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6584: Show issues Location:
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  8. Article ; Online: Acute kidney injury in patients with COVID-19: an update on the pathophysiology.

    Izzedine, Hassan / Jhaveri, Kenar D

    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association

    2020  Volume 36, Issue 2, Page(s) 224–226

    Keywords covid19
    Language English
    Publishing date 2020-09-04
    Publishing country England
    Document type Journal Article
    ZDB-ID 90594-x
    ISSN 1460-2385 ; 0931-0509
    ISSN (online) 1460-2385
    ISSN 0931-0509
    DOI 10.1093/ndt/gfaa184
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    Zs.A 2198: Show issues Location:
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  9. Article: Genes, COVID-19 and phenotype.

    Izzedine, Hassan / Jhaveri, Kenar D / Perazella, Mark A

    Clinical kidney journal

    2021  Volume 14, Issue 5, Page(s) 1485–1487

    Language English
    Publishing date 2021-02-25
    Publishing country England
    Document type Journal Article
    ZDB-ID 2655800-2
    ISSN 2048-8513 ; 2048-8505
    ISSN (online) 2048-8513
    ISSN 2048-8505
    DOI 10.1093/ckj/sfab044
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  10. Article ; Online: Néphrotoxicité du pemetrexed.

    Izzedine, Hassan

    Bulletin du cancer

    2015  Volume 102, Issue 2, Page(s) 190–197

    Abstract: Pemetrexed belongs to a new generation of multitargeted antifolate cytotoxic agents. It is increasingly used as first-line treatment in combination with cisplatin, and as second-line treatment or maintenance monotherapy mainly in metastatic non-small ... ...

    Title translation Pemetrexed nephrotoxicity.
    Abstract Pemetrexed belongs to a new generation of multitargeted antifolate cytotoxic agents. It is increasingly used as first-line treatment in combination with cisplatin, and as second-line treatment or maintenance monotherapy mainly in metastatic non-small cell lung cancer and in malignant mesothelioma. It is increasingly used as first-line treatment in combination with cisplatin in lung adenocarcinoma, and as second-line treatment or maintenance monotherapy in patients mainly controlled by the first-line to progression or poor tolerance. In mesothelioma, pemetrexed is indicated only in first-line with a platinum salt. The main side effect of pemetrexed is myelosuppression, which may be prevented by folinic acid supplementation. This review focuses on the progressive and cumulative emerging renal toxicity of pemetrexed, affecting five to ten percent of "long-term" pemetrexed-treated patients.
    MeSH term(s) Antimetabolites, Antineoplastic/adverse effects ; Antimetabolites, Antineoplastic/pharmacokinetics ; Antineoplastic Combined Chemotherapy Protocols/adverse effects ; Bone Marrow/drug effects ; Clinical Trials as Topic ; Glutamates/adverse effects ; Glutamates/pharmacokinetics ; Guanine/adverse effects ; Guanine/analogs & derivatives ; Guanine/antagonists & inhibitors ; Guanine/pharmacokinetics ; Humans ; Kidney/drug effects ; Leucovorin/administration & dosage ; Neutropenia/chemically induced ; Neutropenia/prevention & control ; Pemetrexed
    Chemical Substances Antimetabolites, Antineoplastic ; Glutamates ; Pemetrexed (04Q9AIZ7NO) ; Guanine (5Z93L87A1R) ; Leucovorin (Q573I9DVLP)
    Language French
    Publishing date 2015-02
    Publishing country France
    Document type English Abstract ; Journal Article ; Review
    ZDB-ID 213270-9
    ISSN 1769-6917 ; 0007-4551
    ISSN (online) 1769-6917
    ISSN 0007-4551
    DOI 10.1016/j.bulcan.2014.12.012
    Database MEDical Literature Analysis and Retrieval System OnLINE

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