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  1. Article ; Online: Decarboxylative Anti-Michael Addition to Olefins Mediated by Photoredox Catalysis.

    Lovett, Gabrielle H / Sparling, Brian A

    Organic letters

    2016  Volume 18, Issue 14, Page(s) 3494–3497

    Abstract: ... access to anti-Michael-type products from readily available precursors. The scope of this methodology was ...

    Abstract Decarboxylative coupling of carboxylic acids with activated olefins has been accomplished using visible light photoredox catalysis. The strategic placement of a radical-stabilizing aromatic group at the β-position of the olefin component biases the regioselectivity of the addition, allowing reliable, facile access to anti-Michael-type products from readily available precursors. The scope of this methodology was demonstrated with a range of carboxylic acids and appropriately substituted olefins and was applied toward a two-step synthesis of the antiarrhythmic agent encainide.
    Language English
    Publishing date 2016-07-15
    Publishing country United States
    Document type Journal Article
    ISSN 1523-7052
    ISSN (online) 1523-7052
    DOI 10.1021/acs.orglett.6b01712
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  2. Article: Decarboxylative Anti-Michael Addition to Olefins Mediated by Photoredox Catalysis

    Lovett, Gabrielle H / Sparling Brian A

    Organic letters. 2016 July 15, v. 18, no. 14

    2016  

    Abstract: ... access to anti-Michael-type products from readily available precursors. The scope of this methodology was ...

    Abstract Decarboxylative coupling of carboxylic acids with activated olefins has been accomplished using visible light photoredox catalysis. The strategic placement of a radical-stabilizing aromatic group at the β-position of the olefin component biases the regioselectivity of the addition, allowing reliable, facile access to anti-Michael-type products from readily available precursors. The scope of this methodology was demonstrated with a range of carboxylic acids and appropriately substituted olefins and was applied toward a two-step synthesis of the antiarrhythmic agent encainide.
    Keywords carboxylic acids ; catalytic activity ; chemical structure ; olefin ; redox reactions ; regioselectivity
    Language English
    Dates of publication 2016-0715
    Size p. 3494-3497.
    Publishing place American Chemical Society
    Document type Article
    ISSN 1523-7052
    DOI 10.1021%2Facs.orglett.6b01712
    Database NAL-Catalogue (AGRICOLA)

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  3. Article ; Online: Missed Healthcare Visits During the COVID-19 Pandemic: A Longitudinal Study.

    Hernandez, Jethel / Batio, Stephanie / Lovett, Rebecca Mullen / Wolf, Michael S / Bailey, Stacy C

    Journal of primary care & community health

    2024  Volume 15, Page(s) 21501319241233869

    Abstract: Introduction: Missed visits have been estimated to cost the U.S. healthcare system $50 billion annually and have been linked to healthcare inefficiency, higher rates of emergency department visits, and worse outcomes. COVID-19 disrupted existing ... ...

    Abstract Introduction: Missed visits have been estimated to cost the U.S. healthcare system $50 billion annually and have been linked to healthcare inefficiency, higher rates of emergency department visits, and worse outcomes. COVID-19 disrupted existing outpatient healthcare utilization patterns. In our study, we sought to examine the frequency of missed outpatient visits over the course of the COVID-19 pandemic and to examine patient-level characteristics associated with non-attendance.
    Methods: This study utilized data from a longitudinal cohort study (the Chicago COVID-19 Comorbidities (C3) study). C3 participants were enrollees in 1 of 4 active, "parent" studies; they were rapidly enrolled in C3 at the onset of the pandemic. Multiple waves of telephone-based interviews were conducted to collect experiences with the pandemic, as well as socio-demographic and health characteristics, health literacy, patient activation, and depressive and anxiety symptoms. For the current analysis, data from waves 3 to 8 (05/01/20-05/19/22) were analyzed. Participants included 845 English or Spanish-speaking adults with 1 or more chronic conditions.
    Results: The percentage of participants reporting missed visits due to COVID-19 across study waves ranged from 3.1 to 22.4%. Overall, there was a decline in missed visits over time. No participant sociodemographic or health characteristic was consistently associated with missed visits across the study waves. In bivariate and multivariate analysis, only patient-reported anxiety was significantly associated with missed visits across all study waves.
    Conclusion: Findings reveal that anxiety was consistently associated with missed visits during the COVID-19 pandemic, but not sociodemographic or health characteristics. Results can inform future public health initiatives to reduce absenteeism by considering patients' emotional state during times of uncertainty.
    MeSH term(s) Adult ; Humans ; COVID-19/epidemiology ; Longitudinal Studies ; Pandemics ; Anxiety/epidemiology ; Delivery of Health Care
    Language English
    Publishing date 2024-02-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2550221-9
    ISSN 2150-1327 ; 2150-1319
    ISSN (online) 2150-1327
    ISSN 2150-1319
    DOI 10.1177/21501319241233869
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  4. Article ; Online: Reality of clonidine poisoning in children and adolescents.

    Duong, Chi / Lovett, Caitlyn / Downes, MIchael A / Isbister, Geoffrey K

    Journal of paediatrics and child health

    2023  Volume 59, Issue 6, Page(s) 827–832

    Abstract: Aim: We aimed to describe the severity of clonidine poisonings in a paediatric population referred to a tertiary toxicology service.: Methods: We undertook a retrospective review of all presentations of clonidine poisoning in children or adolescents ... ...

    Abstract Aim: We aimed to describe the severity of clonidine poisonings in a paediatric population referred to a tertiary toxicology service.
    Methods: We undertook a retrospective review of all presentations of clonidine poisoning in children or adolescents reported to a tertiary toxicology service from March 2014 to February 2020. Cases were divided into young children (0-6 years), older children (7-11 years) and adolescents (12-17 years). We report clinical effects: bradycardia, hypotension and abnormal Glasgow coma score (GCS), based on standard paediatric observation charts, interventions, length of emergency department stay, proportion admitted to a medical ward or paediatric intensive care unit.
    Results: We identified 111 clonidine poisonings, 41 young children, 9 older children and 61 adolescents. There were more females in the adolescent group and slightly more males in the younger age groups. The median dose ingested was 13 mcg/kg (interquartile range: 7-38 mcg/kg), which varied across ages. Clonidine alone was ingested in 78 cases (70%) and co-ingestion was more common in adolescents (24/61; 39%). Thirty-seven patients (33%) were admitted and 23 (21%) were admitted to paediatric intensive care unit. Median length of emergency department stay was 16.4 h, longer for adolescents. At least one abnormal observation occurred in 101 of 111 (91%) cases: 76 of 106 (72%) bradycardia, 76 of 110 (69%) hypotension and 4 of 99 (4%) GCS < 9. Thirteen (12%) had severe bradycardia, more common in young children and 23 (21%) had severe hypotension, more common in adolescents. For 27 children (0-11 years) ingesting 5-10 mcg/kg, 3 (11%) had severe bradycardia or severe hypotension and 1 received naloxone (4%). No cases ingesting <5 mcg/kg developed moderate/severe bradycardia or hypotension. Four cases received naloxone with no significant change, two patients got atropine with a transient response. One patient was intubated to facilitate safe inter-hospital transfer.
    Conclusion: Paediatric clonidine poisoning commonly results in bradycardia, hypotension and decreased GCS, but rarely severe or requiring major interventions. Children ingesting <5 mcg/kg do not require admission.
    MeSH term(s) Male ; Female ; Child ; Humans ; Adolescent ; Child, Preschool ; Clonidine ; Bradycardia/chemically induced ; Atropine ; Hypotension/chemically induced ; Naloxone ; Retrospective Studies ; Poisoning
    Chemical Substances Clonidine (MN3L5RMN02) ; Atropine (7C0697DR9I) ; Naloxone (36B82AMQ7N)
    Language English
    Publishing date 2023-04-10
    Publishing country Australia
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1024476-1
    ISSN 1440-1754 ; 1034-4810
    ISSN (online) 1440-1754
    ISSN 1034-4810
    DOI 10.1111/jpc.16399
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  5. Article: Become a master planner and elevate your practice.

    Lovett, Michael

    Medical economics

    2015  Volume 92, Issue 23, Page(s) 38–9, 42

    MeSH term(s) Appointments and Schedules ; Humans ; Leadership ; Organizational Objectives ; Outcome and Process Assessment (Health Care) ; Planning Techniques ; Practice Management, Medical/economics ; Practice Management, Medical/organization & administration ; Quality Improvement ; Stress, Psychological/prevention & control
    Language English
    Publishing date 2015-12-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 411622-7
    ISSN 0025-7206
    ISSN 0025-7206
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  6. Article: Maximizing the evolving EHR.

    Lovett, Michael

    Health management technology

    2014  Volume 35, Issue 10, Page(s) 20

    MeSH term(s) Diffusion of Innovation ; Electronic Health Records/organization & administration
    Language English
    Publishing date 2014-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1204815-x
    ISSN 1074-4770
    ISSN 1074-4770
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  7. Article: COVID-19 Health Education Activities: An Analysis of a National Sample of Certified Health Education Specialists (CHES

    Chaney, Beth H / Stellefson, Michael L / Opp, Melissa / Allard, Marianne / Chaney, J Don / Lovett, Kylie

    Health promotion practice

    2023  , Page(s) 15248399231184447

    Abstract: The National Commission of Health Education Credentialing, Inc. (NCHEC) created the Category 1 COVID-19 Claim Form Opportunity to document how Certified Health Education Specialists ( ... ...

    Abstract The National Commission of Health Education Credentialing, Inc. (NCHEC) created the Category 1 COVID-19 Claim Form Opportunity to document how Certified Health Education Specialists (CHES
    Language English
    Publishing date 2023-07-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2036801-X
    ISSN 1552-6372 ; 1524-8399
    ISSN (online) 1552-6372
    ISSN 1524-8399
    DOI 10.1177/15248399231184447
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  8. Article ; Online: Characterizing Caregiver Roles and Conflict in Health Management Support to Older People With Multiple Chronic Conditions.

    Russell, Andrea M / Bonham, Morgan / Lovett, Rebecca / Pack, Allison / Wolf, Michael S / O'Conor, Rachel

    Journal of applied gerontology : the official journal of the Southern Gerontological Society

    2023  Volume 43, Issue 4, Page(s) 386–395

    Abstract: Caregivers provide critical support for older adults managing multiple chronic conditions (MCCs), but few studies describe the assistance caregivers provide or identify factors influencing their provision of support. We conducted qualitative interviews ... ...

    Abstract Caregivers provide critical support for older adults managing multiple chronic conditions (MCCs), but few studies describe the assistance caregivers provide or identify factors influencing their provision of support. We conducted qualitative interviews with 25 caregivers to older adults with MCCs to describe caregivers' roles and identify the factors that influence caregivers' ability to carry out these roles. Transcripts were analyzed using the Framework Method. Caregivers supported the management of MCCs in several ways, including monitoring conditions, communicating with clinicians, and tracking health information. Disagreement, or conflicted relationships, between caregivers and older adults over health and behaviors influenced the provision of support, resulting in less involved and less effective caregivers. Caregivers in conflicted relationships were more challenged by resistance from older adults. Greater agreement, or collaboration, between caregivers and older adults resulted in more involved and effective caregivers. Addressing health-related conflict may enhance caregivers' capacity to support older adults with MCCs.
    MeSH term(s) Humans ; Aged ; Multiple Chronic Conditions ; Caregivers
    Language English
    Publishing date 2023-11-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 155897-3
    ISSN 1552-4523 ; 0733-4648
    ISSN (online) 1552-4523
    ISSN 0733-4648
    DOI 10.1177/07334648231211456
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  9. Article ; Online: Barriers and Facilitators Impacting Disease and Symptom Management Among College Students With Type 1 Diabetes: A Qualitative Study.

    McFadden, Ny'Nika T / Wilkerson, Amanda H / Jaiswal, Jessica / Chaney, Beth H / Stellefson, Michael L / Carmack, Heather J / Lovett, Kylie

    American journal of health promotion : AJHP

    2024  , Page(s) 8901171241233407

    Abstract: Purpose: This study aimed to explore barriers and facilitators impacting disease and symptom management among college students living with Type 1 Diabetes (T1D).: Design: A qualitative, phenomenological approach using semi-structured, one-on-one ... ...

    Abstract Purpose: This study aimed to explore barriers and facilitators impacting disease and symptom management among college students living with Type 1 Diabetes (T1D).
    Design: A qualitative, phenomenological approach using semi-structured, one-on-one interviews.
    Setting: Interviews conducted on Zoom (n = 28) and in-person (n = 3).
    Participants: Purposive sample of 31 college students living with T1D for at least 2 years who attended large, 4-year public universities in the Southeastern United States.
    Method: This study was theoretically informed using the Middle-Range Theory of Self-Care of Chronic Illness Integration of Symptoms to develop interview questions. Interviews were transcribed verbatim and uploaded in NVivo. Data were analyzed thematically using a codebook developed by the research team using the theory as a framework. Trustworthiness was established using an audit trail, memos, and negative case analysis.
    Results: Four themes described barriers: diabetes burnout, challenges adjusting to a college lifestyle, difficulty receiving medical supplies, and insurance limitations. Five themes explained facilitators: years of experience managing T1D, tangible support with medical supplies, informational support for disease management, and emotional/technological support for disease and symptom management.
    Conclusion: Barriers and facilitators in this study should be addressed in future T1D interventions for college students. Findings can also guide healthcare professionals, health promotion practitioners, family, friends, and significant others on how to better support college students as they manage T1D.
    Language English
    Publishing date 2024-02-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 645160-3
    ISSN 2168-6602 ; 0890-1171
    ISSN (online) 2168-6602
    ISSN 0890-1171
    DOI 10.1177/08901171241233407
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  10. Article: Outcomes of Cochlear implantation in early-deafened patients with Waardenburg syndrome: A systematic review and narrative synthesis.

    Lovett, Amy / Eastwood, Michael / Metcalfe, Chris / Muzaffar, Jameel / Monksfield, Peter / Bance, Manohar

    Laryngoscope investigative otolaryngology

    2023  Volume 8, Issue 4, Page(s) 1094–1107

    Abstract: Objective: This systematic review aims to establish the expected hearing and speech outcomes following cochlear implantation (CI) in patients with profound congenital deafness secondary to Waardenburg syndrome (WS).: Methods: A systematic review of ... ...

    Abstract Objective: This systematic review aims to establish the expected hearing and speech outcomes following cochlear implantation (CI) in patients with profound congenital deafness secondary to Waardenburg syndrome (WS).
    Methods: A systematic review of the literature and narrative synthesis was performed in accordance with the PRISMA statement. Databases searched: Medline, Pubmed, Embase, Web of Science, Cochrane Collection, and ClinicalTrials.gov. No limits were placed on language or year of publication.
    Results: Searches identified 186 abstracts and full texts. Of these, 16 studies met inclusion criteria reporting outcomes in 179 patients and at least 194 implants. Hearing outcomes of those receiving cochlear implantation were generally good. Five studies included genetic analysis of one or more of the participants. A total of 11 peri/post-operative complications were reported. The methodological quality of included studies was modest, mainly comprising noncontrolled case series with small cohort size. All studies were OCEBM grade III-IV.
    Conclusion: Cochlear implantation in congenitally deafened children with Waardenburg Syndrome is a well-established intervention as a method of auditory rehabilitation. Due to the uncommon nature of the condition, there is a lack of large-scale high-quality studies examining the use of cochlear implantation in this patient group. However, overall outcomes following implantation are positive with the majority of patients demonstrating improved audiometry, speech perception and speech intelligibility supporting its use in appropriately selected cases.
    Language English
    Publishing date 2023-07-11
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 2378-8038
    ISSN 2378-8038
    DOI 10.1002/lio2.1110
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