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  1. Article ; Online: Prevalence of autoimmune diseases in patients with sickle cell disease: a single center retrospective analysis.

    Tang, Man Wai / Nur, Erfan / Van Tuijn, Charlotte F J / Biemond, Bart J

    Haematologica

    2024  

    Abstract: Not available. ...

    Abstract Not available.
    Language English
    Publishing date 2024-03-28
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2333-4
    ISSN 1592-8721 ; 0017-6567 ; 0390-6078
    ISSN (online) 1592-8721
    ISSN 0017-6567 ; 0390-6078
    DOI 10.3324/haematol.2023.284552
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: The association between renal function decline and disease severity in sickle cell disease.

    Gaartman, Aafke E / van Tuijn, Charlotte F J / Nur, Erfan / Vogt, Liffert / Biemond, Bart J

    American journal of hematology

    2023  Volume 98, Issue 5, Page(s) E95–E97

    MeSH term(s) Humans ; Anemia, Sickle Cell/complications ; Patient Acuity ; Kidney/physiology
    Language English
    Publishing date 2023-02-06
    Publishing country United States
    Document type Letter
    ZDB-ID 196767-8
    ISSN 1096-8652 ; 0361-8609
    ISSN (online) 1096-8652
    ISSN 0361-8609
    DOI 10.1002/ajh.26860
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Neutrophils in sickle cell disease: Exploring their potential role as a therapeutic target.

    de Ligt, Lydian A / Gaartman, Aafke E / Biemond, Bart J / Fijnvandraat, Karin / van Bruggen, Robin / Nur, Erfan

    American journal of hematology

    2024  

    Abstract: Factors influencing the activation of neutrophils in SCD and the potential neutrophil-mediated ameliorating effects of therapies in SCD. ...

    Abstract Factors influencing the activation of neutrophils in SCD and the potential neutrophil-mediated ameliorating effects of therapies in SCD.
    Language English
    Publishing date 2024-01-31
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 196767-8
    ISSN 1096-8652 ; 0361-8609
    ISSN (online) 1096-8652
    ISSN 0361-8609
    DOI 10.1002/ajh.27224
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Effect of allogeneic hematopoietic stem cell transplantation on sickle cell disease-related organ complications: A systematic review and meta-analysis.

    Dovern, Elisabeth / Aydin, Mesire / DeBaun, Michael R / Alizade, Komeil / Biemond, Bart J / Nur, Erfan

    American journal of hematology

    2024  

    Abstract: Sickle cell disease (SCD)-related organ complications are a major cause of morbidity and mortality in patients with SCD. We sought to assess whether hematopoietic stem cell transplantation (HSCT) stabilizes, attenuates, or exacerbates organ decline. We ... ...

    Abstract Sickle cell disease (SCD)-related organ complications are a major cause of morbidity and mortality in patients with SCD. We sought to assess whether hematopoietic stem cell transplantation (HSCT) stabilizes, attenuates, or exacerbates organ decline. We performed a systematic review and meta-analysis of trials investigating organ function before and after HSCT in patients with SCD. We searched MEDLINE/PubMed and EMBASE up to September 21, 2023. Continuous data were expressed as standardized mean difference (SMD) and pooled in a weighted inverse-variance random-effects model; binomial data were expressed as risk ratio (RR) using the Mantel-Haenszel random-effects meta-analyses. Of 823 screened studies, 34 were included in this review. Of these, 17 (774 patients, 23.6% adults, 86.3% HLA-identical sibling donor, 56.7% myeloablative conditioning regimen) were included in the meta-analyses. Pulmonary function remained stable. Mean tricuspid regurgitant jet velocity decreased but did not reach statistical significance. In children, estimated glomerular filtration rate decreased (SMD -0.80, p = .01), and the presence of proteinuria increased (RR 2.00, p = <.01), while splenic uptake and phagocytic function improved (RR 0.31, p = <.01; RR 0.23, p = <.01). Cerebral blood flow improved (SMD -1.39, p = <.01), and a low incidence of stroke after transplantation in high-risk patients was found. Retinopathy and avascular osteonecrosis were investigated in only one study, showing no significant changes. While HSCT can improve some SCD-related organ dysfunctions, transplantation-related toxicity may have an adverse effect on others. Future research should focus on identifying individuals with SCD who might benefit most from HSCT and which forms of organ damage are more likely to exacerbate post-transplantation.
    Language English
    Publishing date 2024-03-22
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 196767-8
    ISSN 1096-8652 ; 0361-8609
    ISSN (online) 1096-8652
    ISSN 0361-8609
    DOI 10.1002/ajh.27297
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Thesis procrastination: academic problems in tertiary institutions in Indonesia.

    Ramadhani, Erfan / Setiyosari, Punaji / Indreswari, Henni / Setiyowati, Arbin Janu / Hidayah, Nur / Ramli, M / Situmorang, Dominikus David Biondi

    Journal of public health (Oxford, England)

    2023  Volume 45, Issue 4, Page(s) e827–e828

    MeSH term(s) Humans ; Indonesia ; Procrastination ; Students ; Academic Dissertations as Topic ; Academic Performance
    Language English
    Publishing date 2023-07-13
    Publishing country England
    Document type Research Support, Non-U.S. Gov't ; Letter ; Comment
    ZDB-ID 2142082-8
    ISSN 1741-3850 ; 1741-3842
    ISSN (online) 1741-3850
    ISSN 1741-3842
    DOI 10.1093/pubmed/fdad109
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  6. Article ; Online: Immune thrombocytopenia due to COVID-19 during pregnancy.

    Tang, M W / Nur, Erfan / Biemond, B J

    American journal of hematology

    2020  Volume 95, Issue 8, Page(s) E191–E192

    MeSH term(s) Adult ; Betacoronavirus ; COVID-19 ; Coronavirus Infections/immunology ; Female ; Humans ; Pandemics ; Pneumonia, Viral/immunology ; Pregnancy ; Pregnancy Complications, Hematologic/immunology ; Pregnancy Complications, Hematologic/virology ; Pregnancy Complications, Infectious/immunology ; Pregnancy Complications, Infectious/virology ; SARS-CoV-2 ; Thrombocytopenia/immunology ; Thrombocytopenia/virology
    Keywords covid19
    Language English
    Publishing date 2020-06-11
    Publishing country United States
    Document type Case Reports ; Letter
    ZDB-ID 196767-8
    ISSN 1096-8652 ; 0361-8609
    ISSN (online) 1096-8652
    ISSN 0361-8609
    DOI 10.1002/ajh.25877
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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  7. Article ; Online: Efficacy and safety of daratumumab in pure red cell aplasia after allogeneic transplantation: Dutch real-world data.

    Weverling, Flores / Roeven, Mieke / Nijssen, Clara / Broers, Annoek E C / Dovern, Elisabeth / van Rhenen, Anna / Sluis, Geerte van / Hazenberg, Carin L E / Balen, Peter van / Kuipers, Maria T / de Vooght, Karen M K / Morsink, Linde / Kuball, Jürgen / Nur, Erfan / de Witte, Moniek A

    Blood advances

    2024  Volume 8, Issue 7, Page(s) 1683–1686

    MeSH term(s) Humans ; Red-Cell Aplasia, Pure/drug therapy ; Red-Cell Aplasia, Pure/etiology ; Transplantation, Homologous ; Antibodies, Monoclonal/adverse effects
    Chemical Substances daratumumab (4Z63YK6E0E) ; Antibodies, Monoclonal
    Language English
    Publishing date 2024-01-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2915908-8
    ISSN 2473-9537 ; 2473-9529
    ISSN (online) 2473-9537
    ISSN 2473-9529
    DOI 10.1182/bloodadvances.2023011190
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 7153: Show issues Location:
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  8. Article ; Online: Cerebral hemodynamics and oxygenation in adult patients with sickle cell disease after stem cell transplantation.

    Afzali-Hashemi, Liza / Dovern, Elisabeth / Baas, Koen P A / Schrantee, Anouk / Wood, John C / Nederveen, Aart J / Nur, Erfan / Biemond, Bart J

    American journal of hematology

    2023  Volume 99, Issue 2, Page(s) 163–171

    Abstract: Sickle cell disease (SCD) is characterized by chronic hemolytic anemia associated with impaired cerebral hemodynamics and oxygen metabolism. Hematopoietic stem cell transplantation (HSCT) is currently the only curative treatment for patients with SCD. ... ...

    Abstract Sickle cell disease (SCD) is characterized by chronic hemolytic anemia associated with impaired cerebral hemodynamics and oxygen metabolism. Hematopoietic stem cell transplantation (HSCT) is currently the only curative treatment for patients with SCD. Whereas normalization of hemoglobin levels and hemolysis markers has been reported after HSCT, its effects on cerebral perfusion and oxygenation in adult SCD patients remain largely unexplored. This study investigated the effects of HSCT on cerebral blood flow (CBF), oxygen delivery, cerebrovascular reserve (CVR), oxygen extraction fraction (OEF), and cerebral metabolic rate of oxygen (CMRO
    MeSH term(s) Adult ; Female ; Humans ; Hemolysis ; Anemia, Sickle Cell ; Magnetic Resonance Imaging/methods ; Hemodynamics ; Oxygen/metabolism ; Hematopoietic Stem Cell Transplantation/adverse effects ; Stem Cell Transplantation ; Hemoglobins/metabolism ; Cerebrovascular Circulation/physiology ; Brain/diagnostic imaging ; Brain/metabolism ; Oxygen Consumption
    Chemical Substances Oxygen (S88TT14065) ; Hemoglobins
    Language English
    Publishing date 2023-10-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 196767-8
    ISSN 1096-8652 ; 0361-8609
    ISSN (online) 1096-8652
    ISSN 0361-8609
    DOI 10.1002/ajh.27135
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1251: Show issues Location:
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  10. Article ; Online: Hoping for a normal life: Decision-making on hematopoietic stem cell transplantation by patients with a hemoglobinopathy and their caregivers.

    Mekelenkamp, Hilda / de Vries, Martine / Saalmink, Ineke / Nur, Erfan / Kerkhoffs, Jean-Louis / Heijboer, Harriët / Cnossen, Marjon / Lankester, Arjan / Smiers, Frans

    Pediatric blood & cancer

    2023  Volume 71, Issue 3, Page(s) e30808

    Abstract: Background: To provide insight into the perspectives of children and young adults with transfusion-dependent thalassemia and sickle cell disease and their caregivers regarding the decision for hematopoietic stem cell transplantation (HSCT).: Procedure! ...

    Abstract Background: To provide insight into the perspectives of children and young adults with transfusion-dependent thalassemia and sickle cell disease and their caregivers regarding the decision for hematopoietic stem cell transplantation (HSCT).
    Procedure: A qualitative longitudinal multicenter study. Data collection consisted of 40 audio-recorded conversations between physicians and families and 77 interviews with patients and/or caregivers related to 27 unique cases, collected at different time points throughout the decision-making process.
    Results: Conversations and interviews revealed "hoping for a normal life" as an overarching theme, consisting of four main topics: (i) "Building a frame of reference" refers to a process where patients or families try to obtain comprehensive information on HSCT and translate this to their situation to decide. (ii) "Balancing between loss and benefit" reports the process of considering the advantages and disadvantages of continuing with supportive care to treat their disease versus choosing HSCT. (iii) "Experiencing the impact of HSCT" describes the impactfull experience of the HSCT period by those who chose HSCT. (iv) "Balancing again" refers to reflecting on the decision made.
    Conclusions: The hope for a normal life guided the decision-making process, described as a constant balance between the impact of the disease and HSCT. A structured approach to explore patients' and caregivers' perspectives on HSCT decision-making is needed, where specifically discussing the impact of the disease and hope for a normal life need to be integrated in the process.
    MeSH term(s) Child ; Young Adult ; Humans ; Caregivers ; Patients ; Anemia, Sickle Cell/therapy ; Hematopoietic Stem Cell Transplantation
    Language English
    Publishing date 2023-12-11
    Publishing country United States
    Document type Multicenter Study ; Journal Article
    ZDB-ID 2131448-2
    ISSN 1545-5017 ; 1545-5009
    ISSN (online) 1545-5017
    ISSN 1545-5009
    DOI 10.1002/pbc.30808
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