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  1. Article: Die Zukunft der Qualitätspolitik nach Covid-19 kann nur europäisch sein. Franz-Josef Fischer MBA, Prof. Dr. Kirsten Steinhausen, Prof. Dr. Alain deWever

    Fischer, Franz-Josef / Steinhausen, Kirsten / deWever, Alain

    Das Krankenhaus

    2020  Volume 112, Issue 9, Page(s) 765

    Language German
    Document type Article
    ZDB-ID 3262-1
    ISSN 0340-3602
    Database Current Contents Medicine

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  2. Article: Ich habe gehört, dass die klinische Forschung zur CLL in Köln besonders intensiv betrieben wird. Warum ist das so? Welchen Nutzen habe ich als Patientin davon? - ES ANTWORTEN Barbara Eichhorst und Kirsten Fischer

    Eichhorst, Barbara / Fischer, Kirsten

    Bericht ... / Universitätsklinikum Köln / Klinik I für Innere Medizin

    2017  Volume 2014, Issue -, Page(s) 62

    Language German
    Document type Article
    ZDB-ID 2949853-3
    Database Current Contents Medicine

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  3. Book ; Online: Sustainable Business

    Fischer, Manuel / Foord, Daniel / Frecè, Jan / Hillebrand, Kirsten / Kissling-Näf, Ingrid / Meili, Rahel / Peskova, Marie / Risi, David / Schmidpeter, René / Stucki, Tobias

    Managing the Challenges of the 21st Century

    (SpringerBriefs in Business)

    2023  

    Series title SpringerBriefs in Business
    Keywords Business strategy ; Sustainability ; Business & the environment, 'Green' approaches to business ; Business ethics & social responsibility ; Organization & management of education ; Non-profitmaking organizations ; Circular economy ; Sustainability management ; SDG ; Planetary boundaries ; CSR ; Social innovation ; Stakeholder theory
    Language English
    Size 1 electronic resource (142 pages)
    Publisher Springer Nature
    Publishing place Cham
    Document type Book ; Online
    Note English
    HBZ-ID HT030374485
    ISBN 9783031253966 ; 3031253965
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  4. Book ; Online: Sustainable Business

    Fischer, Manuel / Foord, Daniel / Frecè, Jan / Hillebrand, Kirsten / Kissling-Näf, Ingrid / Meili, Rahel / Peskova, Marie / Risi, David / Schmidpeter, René / Stucki, Tobias

    Managing the Challenges of the 21st Century

    (SpringerBriefs in Business)

    2023  

    Author's details by Manuel Fischer, Daniel Foord, Jan Frecè, Kirsten Hillebrand, Ingrid Kissling-Näf, Rahel Meili, Marie Peskova, David Risi, René Schmidpeter, Tobias Stucki
    Series title SpringerBriefs in Business
    Keywords Strategic planning ; Leadership ; Sustainability ; Industrial management—Environmental aspects ; Business ethics ; School management and organization ; School administration ; Nonprofit organizations
    Language English
    Size 1 Online-Ressource (XVIII, 142 p. 48 illus., 45 illus. in color)
    Edition 1st ed. 2023
    Publisher Springer International Publishing ; Imprint: Springer
    Publishing place Cham
    Document type Book ; Online
    HBZ-ID HT030032579
    ISBN 978-3-031-25397-3 ; 9783031253966 ; 9783031253980 ; 3-031-25397-3 ; 3031253965 ; 3031253981
    DOI 10.1007/978-3-031-25397-3
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  5. Article: Modulation of adenylate cyclase by guanine nucleotides and Kirsten sarcoma virus mediated transformation.

    Saltarelli, D / Fischer, S / Gacon, G

    Biochemical and biophysical research communications

    1985  Volume 127, Issue 1, Page(s) 318–325

    Abstract: ... from fibroblasts (C127) transformed by a temperature sensitive mutant of Kirsten sarcoma virus (Ts 371). The degree ...

    Abstract Certain tumour cells contain activated ras genes that code for 21 000 dalton proteins (p21). These proteins associate with the inner face of the plasma membrane and bind guanine nucleotides specifically. In order to determine whether p21s have functions similar to other GTP binding proteins, we investigated the regulation, by guanine nucleotides, of adenylate cyclase (AC) activity in membrane preparations isolated from fibroblasts (C127) transformed by a temperature sensitive mutant of Kirsten sarcoma virus (Ts 371). The degree of AC stimulation by GMP P(NH)P increased when these cells were shifted from the permissive temperature (33 degrees C) to the non-permissive temperature (39 degrees C). This effect was more pronounced at low Mg++ and low GMP P(NH)P concentrations. AC stimulation remained unchanged in rat fibroblasts infected with a temperature sensitive mutant of Rous Sarcoma virus. AC activity was depressed in C127 cells infected with wild type KiMSV. Our data illustrate the feasibility of correlating alterations in the AC system with ras gene expression and using such experimental approaches to elucidate the physiological functions of the p21 proteins.
    MeSH term(s) Adenylyl Cyclases/metabolism ; Animals ; Cell Transformation, Viral ; Cyclic AMP/biosynthesis ; Fibroblasts/enzymology ; Guanine Nucleotides/pharmacology ; Kirsten murine sarcoma virus ; Magnesium/metabolism ; Mice ; Neoplasm Proteins/metabolism ; Temperature
    Chemical Substances Guanine Nucleotides ; Neoplasm Proteins ; Cyclic AMP (E0399OZS9N) ; Adenylyl Cyclases (EC 4.6.1.1) ; Magnesium (I38ZP9992A)
    Language English
    Publishing date 1985-02-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 205723-2
    ISSN 0006-291X ; 0006-291X
    ISSN (online) 0006-291X
    ISSN 0006-291X
    DOI 10.1016/s0006-291x(85)80161-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Book ; Thesis: Zur Bedeutung der frühen Besiedelung mit Nicht-Pseudomonas Keimen für die spätere Pseudomonas Besiedelung bei Zystischer Fibrose

    Fischer, Kirsten

    2006  

    Author's details vorgelegt von Kirsten Fischer, geb. Leiwig
    Language German
    Size III, 76 S. Ill., graph. Darst.
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Köln, Univ., Diss., 2006
    HBZ-ID HT014972731
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    2007 D 284 order for loan Magazin

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  7. Article ; Online: TP53 mutations in CLL: does frequency matter?

    Al-Sawaf, Othman / Fischer, Kirsten

    Blood

    2022  Volume 138, Issue 25, Page(s) 2600–2601

    MeSH term(s) Genes, p53 ; Humans ; Leukemia, Lymphocytic, Chronic, B-Cell/genetics ; Mutation ; Tumor Suppressor Protein p53/genetics
    Chemical Substances TP53 protein, human ; Tumor Suppressor Protein p53
    Language English
    Publishing date 2022-01-20
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 80069-7
    ISSN 1528-0020 ; 0006-4971
    ISSN (online) 1528-0020
    ISSN 0006-4971
    DOI 10.1182/blood.2021012343
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Acalabrutinib monotherapy in patients with Richter transformation.

    Fischer, Kirsten / Al-Sawaf, Othman

    The Lancet. Haematology

    2021  Volume 8, Issue 12, Page(s) e868–e870

    MeSH term(s) Benzamides/therapeutic use ; Humans ; Leukemia, Lymphocytic, Chronic, B-Cell ; Lymphoma, Large B-Cell, Diffuse ; Pyrazines
    Chemical Substances Benzamides ; Pyrazines ; acalabrutinib (I42748ELQW)
    Language English
    Publishing date 2021-11-01
    Publishing country England
    Document type Journal Article ; Comment
    ISSN 2352-3026
    ISSN (online) 2352-3026
    DOI 10.1016/S2352-3026(21)00334-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Benefits and Shortcomings of Laboratory Model Systems in the Development of Genetic Therapies.

    Bucher, Kirsten / Rodriguez-Bocanegra, Eduardo / Fischer, M Dominik

    Klinische Monatsblatter fur Augenheilkunde

    2022  Volume 239, Issue 3, Page(s) 263–269

    Abstract: Gene therapeutic approaches promise treatment or even a cure of diseases that were previously untreatable. Retinal gene therapies tested in clinical trials comprise a wide range of different strategies, including gene supplementation therapies, ...

    Title translation Vorteile und Defizite von Labormodellsystemen bei der Entwicklung von Gentherapieverfahren.
    Abstract Gene therapeutic approaches promise treatment or even a cure of diseases that were previously untreatable. Retinal gene therapies tested in clinical trials comprise a wide range of different strategies, including gene supplementation therapies,
    MeSH term(s) Dependovirus/genetics ; Genetic Therapy ; Humans ; Models, Biological ; Retina
    Language English
    Publishing date 2022-03-22
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 80175-6
    ISSN 1439-3999 ; 0344-6360 ; 0344-6387 ; 0023-2165
    ISSN (online) 1439-3999
    ISSN 0344-6360 ; 0344-6387 ; 0023-2165
    DOI 10.1055/a-1757-9879
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Book ; Thesis: Erhebungen zum Fruchtbarkeitsstatus von Milchkühen, Beziehungen zu Blutparametern sowie dem allgemeinen und gynäkologischen Status

    Fischer, Kirsten

    eine explorative Datenanalyse

    1996  

    Author's details von Kirsten Fischer
    Size V, 187 S. : graph. Darst.
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Gießen, Univ., Diss., 1996
    Note Zsfassung in engl. Sprache
    Remark Abt. Nussallee/Bereichsbibl. ZBMed: AY 18026
    HBZ-ID HT007344829
    Database Catalogue ZB MED Nutrition, Environment, Agriculture

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    In stock of ZB MED Bonn / Germany

    Shelf markLoan statusLocation
    968/3421 available for loan (reading room) Freihandmagazin (U1)

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