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  1. Article: Novel In-Frame Deletion

    Lee, Cha Gon / Kim, Hyun Jung / Seol, Chang Ahn / Ki, Chang-Seok

    Neurology. Genetics

    2024  Volume 10, Issue 1, Page(s) e200116

    Abstract: Objectives: Intellectual developmental disorder with speech delay, autism, and dysmorphic facies (IDDSADF) is caused by heterozygous : Methods: We conducted whole-exome sequencing and confirmatory Sanger sequencing on the proband, the mother, and ... ...

    Abstract Objectives: Intellectual developmental disorder with speech delay, autism, and dysmorphic facies (IDDSADF) is caused by heterozygous
    Methods: We conducted whole-exome sequencing and confirmatory Sanger sequencing on the proband, the mother, and unaffected grandparents with wild-type genotypes.
    Results: The phenotypes of the mother and 2 daughters presented muscular hypotonia, global developmental delay, speech delay, intellectual disability, macrocephaly, facial dysmorphic features, and focal corpus callosum hypoplasia. Whole-exome sequencing identified a novel in-frame deletion, c.2017_2019del (p.Phe673del) in
    Discussion: This report presents a new possible mechanism underlying IDDSADF caused by CNOT3 variants-an in-frame deletion. The findings enhance our understanding of early-life neurodevelopment and the genotype-phenotype relationships of IDDSADF caused by
    Language English
    Publishing date 2024-01-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2818607-2
    ISSN 2376-7839
    ISSN 2376-7839
    DOI 10.1212/NXG.0000000000200116
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Enhancing Microalgae Content in Biocomposites through a Mechanical Grinding Method.

    Kim, Minju / Kim, Gyu Min / Chang, Won-Seok / Kim, Young-Kee

    Polymers

    2023  Volume 15, Issue 23

    Abstract: Microalgae-based biocomposites are gaining traction as ecofriendly and cost-effective alternatives to conventional petroleum-based plastics. However, achieving a homogeneous dispersion of microalgae within a biocomposite matrix remains a challenge. In ... ...

    Abstract Microalgae-based biocomposites are gaining traction as ecofriendly and cost-effective alternatives to conventional petroleum-based plastics. However, achieving a homogeneous dispersion of microalgae within a biocomposite matrix remains a challenge. In this study, we investigated the effect of the size of dried microalgae (
    Language English
    Publishing date 2023-11-28
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527146-5
    ISSN 2073-4360 ; 2073-4360
    ISSN (online) 2073-4360
    ISSN 2073-4360
    DOI 10.3390/polym15234557
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  3. Article ; Online: Chryseobacterium paludis sp. nov. and Chryseobacterium foetidum sp. nov. Isolated from the Aquatic Environment, South Korea.

    Kim, Miryung / Kim, Yong-Seok / Cha, Chang-Jun

    Journal of microbiology (Seoul, Korea)

    2023  Volume 61, Issue 1, Page(s) 37–47

    Abstract: Two novel bacterial species ... ...

    Abstract Two novel bacterial species CJ51
    MeSH term(s) Chryseobacterium/genetics ; Phylogeny ; RNA, Ribosomal, 16S/genetics ; Bacterial Typing Techniques ; Base Composition ; DNA, Bacterial/genetics ; Sequence Analysis, DNA ; Nucleic Acid Hybridization ; Fatty Acids ; Republic of Korea ; Vitamin K 2
    Chemical Substances RNA, Ribosomal, 16S ; DNA, Bacterial ; Fatty Acids ; Vitamin K 2 (11032-49-8)
    Language English
    Publishing date 2023-02-01
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 2012399-1
    ISSN 1976-3794 ; 1225-8873
    ISSN (online) 1976-3794
    ISSN 1225-8873
    DOI 10.1007/s12275-022-00008-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5211: Show issues Location:
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  4. Article: Tilted implants for implant-supported fixed hybrid prostheses: retrospective review.

    Seok, Woo-Hyun / Yun, Pil-Young / Chang, Na-Hee / Kim, Young-Kyun

    Journal of the Korean Association of Oral and Maxillofacial Surgeons

    2023  Volume 49, Issue 5, Page(s) 278–286

    Abstract: Objectives: This review assessed the performance of implant-supported fixed hybrid prostheses in 21 patients who received a total of 137 implants between 2003 and 2010. The implants were evaluated for marginal bone resorption, complications, success ... ...

    Abstract Objectives: This review assessed the performance of implant-supported fixed hybrid prostheses in 21 patients who received a total of 137 implants between 2003 and 2010. The implants were evaluated for marginal bone resorption, complications, success rate, and survival rate based on their vertical angularity, type of bone graft, and measured implant stability.
    Materials and methods: One-way ANOVA and chi-square tests were used to analyze the relationships among long-term evaluation factors and these variables. The mean initial bone resorption in the implant group with a vertical angle of more than 20° was 0.33 mm and mean final bone resorption was 0.76 mm. In contrast, the mean initial bone resorption in the implant group with a vertical angle of less than 10° was 1.19 mm and mean final bone resorption was 2.17 mm.
    Results: The results showed that mean bone resorption decreased with an increase in the vertical placement angle of the implants used in fixed hybrid prostheses, as well as in the group without additional bone grafts and those with high implant stability. The success rate of implants placed after bone grafting was found to be higher than those placed simultaneously.
    Conclusion: These results suggest that implant-supported fixed hybrid prostheses may be an effective treatment option for edentulous patients, and intentionally placing implants with high angularity may improve outcomes.
    Language English
    Publishing date 2023-10-31
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 2763851-0
    ISSN 2234-5930 ; 2234-7550
    ISSN (online) 2234-5930
    ISSN 2234-7550
    DOI 10.5125/jkaoms.2023.49.5.278
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  5. Article ; Online: Mechanistic Approach Toward the C4-Selective Amination of Pyridines via Nucleophilic Substitution of Hydrogen.

    Choi, Hoonchul / Ham, Won Seok / van Bonn, Pit / Zhang, Jianbo / Kim, Dongwook / Chang, Sukbok

    Angewandte Chemie (International ed. in English)

    2024  , Page(s) e202401388

    Abstract: The development of site-selective functionalization of N-heteroarenes is highly desirable in streamlined synthesis. In this context, direct amination of pyridines stands as an important synthetic methodology, with particular emphasis on accessing 4- ... ...

    Abstract The development of site-selective functionalization of N-heteroarenes is highly desirable in streamlined synthesis. In this context, direct amination of pyridines stands as an important synthetic methodology, with particular emphasis on accessing 4-aminopyridines, a versatile pharmacophore in medicinal chemistry. Herein, we report a reaction manifold for the C4-selective amination of pyridines by employing nucleophilic substitution of hydrogen (S
    Language English
    Publishing date 2024-04-08
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2011836-3
    ISSN 1521-3773 ; 1433-7851
    ISSN (online) 1521-3773
    ISSN 1433-7851
    DOI 10.1002/anie.202401388
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  6. Article: Are Electronic Cigarettes Harmful? Mucin May Be the Key.

    Rha, Min-Seok / Kim, Chang-Hoon

    Clinical and experimental otorhinolaryngology

    2021  Volume 14, Issue 3, Page(s) 249–250

    Language English
    Publishing date 2021-08-01
    Publishing country Korea (South)
    Document type Editorial
    ZDB-ID 2491719-9
    ISSN 2005-0720 ; 1976-8710
    ISSN (online) 2005-0720
    ISSN 1976-8710
    DOI 10.21053/ceo.2021.00906
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  7. Article ; Online: Comparison of delayed bleeding to immediate bleeding following thyroidectomy.

    Lee, Jun Sung / Lee, Jin Seok / Yun, Hyeok Jun / Chang, Hojin / Kim, Seok-Mo / Lee, Yong Sang / Chang, Hang-Seok

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 18342

    Abstract: It is important to identify risk factors for post-thyroidectomy bleeding requiring airway intervention or reoperation. Therefore, we aimed to compare the characteristics of patients with postoperative bleeding after thyroid surgery according to the ... ...

    Abstract It is important to identify risk factors for post-thyroidectomy bleeding requiring airway intervention or reoperation. Therefore, we aimed to compare the characteristics of patients with postoperative bleeding after thyroid surgery according to the period until reoperation. We conducted a retrospective study analyzing data between April 2009 and July 2022 and included 126 patients who had postoperative bleeding. The patients were grouped according to the period between thyroidectomy and reoperation due to bleeding (0 day, 1-7 days, > 7 days). We performed among-group comparisons of patient characteristics and surgical aspects, including the extent of surgery. The ratios of male-female and lateral neck dissection were higher in the post-operative bleeding group than in the group without bleeding. In the analysis of patients with postoperative bleeding, grouped according to period between thyroidectomy and reoperation, there was a significant among-group difference in the male-female ratio. The male sex was positively correlated with the reoperation period. Further, the reoperation period was also positively correlated with total thyroidectomy and lateral neck dissection and the operation time showed a significant among-group difference. Our results indicate that the male sex and lateral neck dissection are risk factors for postoperative bleeding after thyroidectomy. Furthermore, male sex, total thyroidectomy, and lateral neck dissection are risk factors for delayed bleeding. Therefore, clinicians should consider these factors for interventions against immediate or delayed bleeding after thyroidectomy.
    MeSH term(s) Humans ; Male ; Female ; Thyroidectomy/adverse effects ; Thyroidectomy/methods ; Retrospective Studies ; Thyroid Gland ; Neck Dissection/adverse effects ; Neck Dissection/methods ; Postoperative Hemorrhage/epidemiology ; Postoperative Hemorrhage/etiology ; Thyroid Neoplasms/etiology
    Language English
    Publishing date 2023-10-26
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-44323-z
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  8. Article: Pediatric Benign Paroxysmal Positional Vertigo: Degree of Nystagmus and Concurrent Dizziness Differs from Adult BPPV.

    An, Jun Beom / Kim, Jisu / Park, Seok Hyun / Yoon, Joonsung / Choo, Oak Sung / Park, Su-Kyoung / Chang, Jiwon

    Journal of clinical medicine

    2024  Volume 13, Issue 7

    Abstract: ... ...

    Abstract Background
    Language English
    Publishing date 2024-03-29
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm13071997
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  9. Article: Buckling resistance, torque, and force generation during retreatment with D-RaCe, HyFlex Remover, and Mtwo retreatment files.

    Kim, Yoojin / Chang, Seok Woo / Oh, Soram

    Restorative dentistry & endodontics

    2023  Volume 48, Issue 1, Page(s) e10

    Abstract: Objectives: This study compared the buckling resistance of 3 nickel-titanium (NiTi) retreatment file systems and the torque/force generated during retreatment.: Materials and methods: The buckling resistance was compared among the D-RaCe (DR2), ... ...

    Abstract Objectives: This study compared the buckling resistance of 3 nickel-titanium (NiTi) retreatment file systems and the torque/force generated during retreatment.
    Materials and methods: The buckling resistance was compared among the D-RaCe (DR2), HyFlex Remover, and Mtwo R25/05 retreatment systems. J-shaped canals within resin blocks were prepared with ProTaper NEXT X3 and obturated by the single-cone technique with AH Plus. After 4 weeks, 4 mm of gutta-percha in the coronal aspect was removed with Gates-Glidden drills. Retreatment was then performed using DR1 (size 30, 10% taper) followed by DR2 (size 25, 4% taper), HyFlex Remover (size 30, 7% taper), or Mtrwo R25/05 (size 25, 5% taper) (15 specimens in each group). Further apical preparation was performed with WaveOne Gold Primary. The clockwise torque and upward force generated during retreatment were recorded. After retreatment, resin blocks were examined using stereomicroscopy, and the percentage of residual filling material in the canal area was calculated. Data were analyzed using 1-way analysis of variance with the Tukey test.
    Results: The HyFlex Remover files exhibited the greatest buckling resistance (
    Conclusions: NiTi retreatment instruments with higher buckling resistance generated greater clockwise torque and upward force.
    Language English
    Publishing date 2023-02-06
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 2715357-5
    ISSN 2234-7666 ; 2234-7658
    ISSN (online) 2234-7666
    ISSN 2234-7658
    DOI 10.5395/rde.2023.48.e10
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  10. Article ; Online: Robotic parathyroidectomy is a feasible technique for primary hyperparathyroidism.

    Lee, Jin Seok / Lee, Jun Sung / Jeong, Hojung / Yun, Hyeok Jun / Chang, Hojin / Kim, Seok Mo / Lee, Yong Sang / Chang, Hang-Seok

    Langenbeck's archives of surgery

    2023  Volume 409, Issue 1, Page(s) 10

    Abstract: Purpose: Focused parathyroidectomy is the gold standard treatment modality for primary hyperparathyroidism, which allows accurate preoperative localization. Robotic parathyroidectomy has emerged as a feasible procedure for focused parathyroidectomy. ... ...

    Abstract Purpose: Focused parathyroidectomy is the gold standard treatment modality for primary hyperparathyroidism, which allows accurate preoperative localization. Robotic parathyroidectomy has emerged as a feasible procedure for focused parathyroidectomy. This study aimed to report the experiences of gasless robotic transaxillary parathyroidectomy for primary hyperparathyroidism in a single center.
    Methods: We assessed the data obtained from patients who underwent gasless robotic parathyroidectomy with the transaxillary approach between December 2013 and August 2022 and were diagnosed with primary hyperparathyroidism at our institute. The data included clinical, biochemical, and pathological features and operation time.
    Results: Of the 12 patients, 11 were women and one was a man. The median age of the patients was 44.5 years (range: 15-65 years). The median preoperative maximum mass diameters on ultrasonography and neck computed tomography were 1.2 ± 0.5 and 1.1 ± 0.6 cm, respectively. The median size of the postoperative maximum mass diameter in gross pathology was 1.3 ± 0.4 cm. The location of the enlarged parathyroid was left superior in five patients, right inferior in four, left inferior in three, and no right superior in one. In the final pathological examination, all cases were parathyroid adenomas. Only one case experienced a postoperative bleeding complication. At six months from surgery, average of an axillary scar length was 5.85 cm, and an average width was 0.21 cm. The mean operative time was 113 ± 48 min. The mean robot docking and console times were 9 ± 5 and 47 ± 52 min, respectively.
    Conclusions: Robotic transaxillary parathyroidectomy is a feasible technique in select patients with primary hyperparathyroidism and preoperatively localized disease. The gasless robotic transaxillary approach provides procedural safety as well as superior cosmetic results without a neck scar.
    MeSH term(s) Male ; Humans ; Female ; Adolescent ; Young Adult ; Adult ; Middle Aged ; Aged ; Robotics ; Parathyroidectomy/methods ; Robotic Surgical Procedures/methods ; Hyperparathyroidism, Primary/diagnostic imaging ; Hyperparathyroidism, Primary/surgery ; Cicatrix/surgery ; Postoperative Complications/surgery
    Language English
    Publishing date 2023-12-16
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1423681-3
    ISSN 1435-2451 ; 1435-2443
    ISSN (online) 1435-2451
    ISSN 1435-2443
    DOI 10.1007/s00423-023-03182-y
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    In stock of ZB MED Cologne/Königswinter

    Uk I Zs.10: Show issues Location:
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