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  1. Article: One Fell Swoop: Septic Muscle Embolism and Central Venous Catheter Infection Imaged with [

    Filippi, Luca / Lacanfora, Annamaria / Garaci, Francesco

    Diagnostics (Basel, Switzerland)

    2024  Volume 14, Issue 2

    Abstract: We describe the case of a 43-year-old female with hereditary hemochromatosis, previously without cardiac issues, who presented with a severe fever (>40 to 41 °C) to our hospital. Initial assessments, including transthoracic echocardiography, showed no ... ...

    Abstract We describe the case of a 43-year-old female with hereditary hemochromatosis, previously without cardiac issues, who presented with a severe fever (>40 to 41 °C) to our hospital. Initial assessments, including transthoracic echocardiography, showed no typical signs of infective endocarditis. A contrast-enhanced CT scan revealed a hypodense area in the right subscapular muscle, alongside pleural thicknesses. Due to the critical condition, a central venous catheter (CVC) was implanted for immediate intravenous treatment. Subsequent blood cultures, positive for
    Language English
    Publishing date 2024-01-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662336-5
    ISSN 2075-4418
    ISSN 2075-4418
    DOI 10.3390/diagnostics14020180
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Peritoneal Carcinomatosis of Malignant Gynecological Origin: A Systematic Review of Imaging Assessment.

    Meucci, Rosaria / Prosperi, Daniela / Lauri, Chiara / Campagna, Giuseppe / Nayak, Pallavi / Garaci, Francesco / Signore, Alberto

    Journal of clinical medicine

    2024  Volume 13, Issue 5

    Abstract: This systematic review, conducted using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) protocol, aims to comprehensively assess the current state of the art of imaging modalities for the evaluation of peritoneal ... ...

    Abstract This systematic review, conducted using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) protocol, aims to comprehensively assess the current state of the art of imaging modalities for the evaluation of peritoneal carcinomatosis arising from malignant gynecological origins, with a focus on ovarian and endometrial cancers. A systematic search of relevant databases was performed, adhering to predetermined inclusion and exclusion criteria. Studies reporting the use of computed tomography (CT), magnetic resonance imaging (MRI), fluorodeoxyglucose (FDG) positron emission tomography (PET), PET/CT, and PET/MRI in the assessment of peritoneal carcinomatosis from gynecological malignancies were included. The review encompasses an overview of selected studies, highlighting the strengths and limitations of each imaging modality in diagnosing and characterizing peritoneal carcinomatosis. Overall, a wide variability in the reported accuracy of different imaging techniques emerges from literature, mainly due to the type of the study, technical issues, and patient characteristics. Although a meta-analysis could not be performed due to a scarcity of data, this systematic review provides valuable insights into the several imaging approaches used in peritoneal carcinomatosis of gynecological origin. The findings aim to inform clinical decision making and guide future research endeavors in this critical aspect of gynecological oncology.
    Language English
    Publishing date 2024-02-22
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm13051254
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  3. Article: Transperineal Laser Ablation (TPLA) Treatment of Focal Low-Intermediate Risk Prostate Cancer.

    Manenti, Gugliemo / Perretta, Tommaso / Nezzo, Marco / Fraioli, Federico Romeo / Carreri, Beatrice / Gigliotti, Paola Elda / Micillo, Andrea / Malizia, Andrea / Di Giovanni, Daniele / Ryan, Colleen Patricia / Garaci, Francesco Giuseppe

    Cancers

    2024  Volume 16, Issue 7

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2024-04-03
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers16071404
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  4. Article ; Online: MRI and Clinical Biomarkers Overlap between Glaucoma and Alzheimer's Disease.

    Martucci, Alessio / Di Giuliano, Francesca / Minosse, Silvia / Pocobelli, Giulio / Nucci, Carlo / Garaci, Francesco

    International journal of molecular sciences

    2023  Volume 24, Issue 19

    Abstract: Glaucoma is the leading cause of blindness worldwide. It is classically associated with structural and functional changes in the optic nerve head and retinal nerve fiber layer, but the damage is not limited to the eye. The involvement of the central ... ...

    Abstract Glaucoma is the leading cause of blindness worldwide. It is classically associated with structural and functional changes in the optic nerve head and retinal nerve fiber layer, but the damage is not limited to the eye. The involvement of the central visual pathways and disruption of brain network organization have been reported using advanced neuroimaging techniques. The brain structural changes at the level of the areas implied in processing visual information could justify the discrepancy between signs and symptoms and underlie the analogy of this disease with neurodegenerative dementias, such as Alzheimer's disease, and with the complex group of pathologies commonly referred to as "disconnection syndromes." This review aims to summarize the current state of the art on the use of advanced neuroimaging techniques in glaucoma and Alzheimer's disease, highlighting the emerging biomarkers shared by both diseases.
    MeSH term(s) Humans ; Alzheimer Disease/diagnostic imaging ; Alzheimer Disease/pathology ; Magnetic Resonance Imaging/methods ; Glaucoma/diagnostic imaging ; Glaucoma/pathology ; Neuroimaging ; Brain/diagnostic imaging ; Brain/pathology ; Biomarkers
    Chemical Substances Biomarkers
    Language English
    Publishing date 2023-10-05
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms241914932
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Low-Dose Occupational Exposure to Ionizing Radiation and Cardiovascular Effects: A Narrative Review.

    Manenti, Guglielmo / Coppeta, Luca / Kirev, Ivan Valentinov / Verno, Greta / Garaci, Francesco / Magrini, Andrea / Floris, Roberto

    Healthcare (Basel, Switzerland)

    2024  Volume 12, Issue 2

    Abstract: Historically, non-cancer diseases have not been considered a health risk following low-dose exposure to ionizing radiation. However, it is now well known that high-dose ionizing radiation causes cardiovascular disease, and emerging epidemiological ... ...

    Abstract Historically, non-cancer diseases have not been considered a health risk following low-dose exposure to ionizing radiation. However, it is now well known that high-dose ionizing radiation causes cardiovascular disease, and emerging epidemiological evidence suggests an excess risk of non-cancer diseases even following exposure to lower doses of ionizing radiation than previously thought. In fact, the evidence is strongest for cardiovascular disease (CVD). The aim of this review was to report the most representative studies and data on the risk of CVD from low-dose radiation in people with occupational exposure. We reported the results of 27 articles selected from a database search of 1151 studies. The results show a complex evidence landscape on the relationship between radiation exposure and cardiovascular disease. In general, published papers show a positive association between ionizing radiation exposure and dermal microcirculation damage, ischemic heart disease, and cerebrovascular disease. Overall, they highlight the need for comprehensive and detailed research to clarify this relationship. Due to limited statistical power, the dose-risk relationship below 0.5 Gy is inconclusive, but if this relationship is found to have no threshold, it could have a significant impact on current estimates of health risks at low doses.
    Language English
    Publishing date 2024-01-18
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2721009-1
    ISSN 2227-9032
    ISSN 2227-9032
    DOI 10.3390/healthcare12020238
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  6. Article: Incidental finding of intrathoracic caudate lobe of the liver associated with an arterovenous malformation.

    D'Errico, Francesca / Laudazi, Mario / Pitaro, Maria / Pietropaolo, Aniello / Paoloantonio, Pasquale / Garaci, Francesco / Floris, Roberto / Chiocchi, Marcello

    Radiology case reports

    2023  Volume 18, Issue 3, Page(s) 1186–1189

    Abstract: In this case report we describe an occasional finding of intrathoracic caudate lobe protruding through the diaphragm foramen in a 73-year-old woman who came to our attention for a screening for coronary artery disease, due to the presence of ... ...

    Abstract In this case report we describe an occasional finding of intrathoracic caudate lobe protruding through the diaphragm foramen in a 73-year-old woman who came to our attention for a screening for coronary artery disease, due to the presence of cardiovascular risk. The patient had no symptoms. The computed tomography showed, a circumscribed homogeneous soft tissue mass that protruding through the aortic diaphragmatic foramen that was as isodense as the liver. Moreover was revealed an abnormal artery emerging from the celiac tripod which, through the diaphragmatic foramen, ends in an inferior pulmonary vein creating an arteriovenous malformation.
    Language English
    Publishing date 2023-01-11
    Publishing country Netherlands
    Document type Case Reports
    ZDB-ID 2406300-9
    ISSN 1930-0433
    ISSN 1930-0433
    DOI 10.1016/j.radcr.2022.12.008
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  7. Article: Colo-colic intussusception in an adult caused by lipoma: Case report of a rare condition.

    Di Stefano, Carla / Salvatori, Eva / Savino, Luca / Forte, Valentina / Paoletti, Stefano / Ricciardi, Federica / Floris, Roberto / Garaci, Francesco

    Radiology case reports

    2023  Volume 19, Issue 2, Page(s) 665–670

    Abstract: This report describes the case of a 56-year-old woman who presented at the emergency room with a 3-week history of severe, intermittent abdominal pain. A CT scan revealed colo-colic intussusception caused by a large, substenosing mass with predominant ... ...

    Abstract This report describes the case of a 56-year-old woman who presented at the emergency room with a 3-week history of severe, intermittent abdominal pain. A CT scan revealed colo-colic intussusception caused by a large, substenosing mass with predominant adipose density. Subsequent endoscopic examination with biopsy revealed a necrotic tissue covering the mass, without definitive histological characterization. A second biopsy led to the extremely rare diagnosis of colo-colic lipoma. While intussusception is rare in adults, it's important to consider it as a differential diagnosis, especially when presenting with abdominal pain and signs of bowel obstruction. Timely diagnosis and appropriate treatment are essential to prevent complications.
    Language English
    Publishing date 2023-11-25
    Publishing country Netherlands
    Document type Case Reports
    ZDB-ID 2406300-9
    ISSN 1930-0433
    ISSN 1930-0433
    DOI 10.1016/j.radcr.2023.10.080
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  8. Article ; Online: Letter to the Editor Regarding "Possible Prognostic Role of Magnetic Resonance Imaging Findings in Patients with Trigeminal Neuralgia and Multiple Sclerosis who Underwent Percutaneous Balloon Compression: Report of Our Series and Literature Review".

    Fraioli, Mario Francesco / Scalia, Gianluca / Garaci, Francesco Giuseppe / Fraioli, Chiara / Lunardi, Pierpaolo / Umana, Giuseppe Emmanuele

    World neurosurgery

    2020  Volume 136, Page(s) 433–434

    MeSH term(s) Balloon Occlusion ; Humans ; Magnetic Resonance Imaging ; Multiple Sclerosis ; Prognosis ; Trigeminal Neuralgia
    Language English
    Publishing date 2020-01-11
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2534351-8
    ISSN 1878-8769 ; 1878-8750
    ISSN (online) 1878-8769
    ISSN 1878-8750
    DOI 10.1016/j.wneu.2020.01.063
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: The role of cardiac computed tomography in diagnostic and prognostic assessment of pregnancy related spontaneous coronary artery dissection: a case report.

    Luciano, Alessandra / Cerimele, Cecilia / Mecchia, Daniele / Mozzani, Marcello / Steffani, Simone / D'Errico, Francesca / Di Donna, Carlo / De Stasio, Vincenzo / Garaci, Francesco / Chiocchi, Marcello

    Oxford medical case reports

    2024  Volume 2024, Issue 4, Page(s) omae030

    Abstract: Spontaneous coronary artery dissection (SCAD) is the most common cause of myocardial infarction during pregnancy or the postpartum period and has a major impact on cardiovascular morbidity and death in pregnant women. A 38-year-old woman with sudden ... ...

    Abstract Spontaneous coronary artery dissection (SCAD) is the most common cause of myocardial infarction during pregnancy or the postpartum period and has a major impact on cardiovascular morbidity and death in pregnant women. A 38-year-old woman with sudden cardiac arrest ten days postpartum urgently underwent coronarography, which showed an intraparietal hematoma of the left anterior descending (LAD) artery. Two days later, coronary computed tomography angiography (CCTA) was performed, which showed the evidence of SCAD in the mid-distal tract of LAD and the presence of transmural ischemic infarction in the apex and mid antero-septal wall in delayed acquisition. The patient was treated with a beta-blocker. Four months later CCTA showed complete resolution of SCAD and evolution of the infarcted areas. Given the high accuracy and noninvasiveness of CCTA, our case highlights the potential role of this imaging modality in the diagnosis and follow-up of pregnancy associated SCAD.
    Language English
    Publishing date 2024-04-25
    Publishing country England
    Document type Case Reports
    ZDB-ID 2766251-2
    ISSN 2053-8855
    ISSN 2053-8855
    DOI 10.1093/omcr/omae030
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  10. Article: Radiological findings in Erdheim Chester disease: A very rare multisistemic disease.

    Chiocchi, Marcello / Luciano, Alessandra / De Stasio, Vincenzo / Pugliese, Luca / Di Donna, Carlo / Cerocchi, Martina / Gigliotti, Paola / Carini, Alessandro / Chirico, Flavia / Camedda, Riccardo / Di Biagio, Daniele / Sbordone, Paolo Francesco / Garaci, Francesco / Floris, Roberto

    Radiology case reports

    2023  Volume 18, Issue 5, Page(s) 2047–2054

    Abstract: Erdheim-Chester disease is an uncommon non-Langerhans cell histiocytosis affecting multiple systems. There is limited knowledge on the imaging capabilities of this disease. We present an extremely rare case of Erdheim-Chester illness in a 67-year-old man ...

    Abstract Erdheim-Chester disease is an uncommon non-Langerhans cell histiocytosis affecting multiple systems. There is limited knowledge on the imaging capabilities of this disease. We present an extremely rare case of Erdheim-Chester illness in a 67-year-old man with multisystem involvement, including the cardiovascular system, skeleton, retroperitoneum (renal and adrenal infiltration) and the neurologic system. The involvement of the various organs was thoroughly assessed using multimodal imaging modalities such as computed tomography, magnetic resonance imaging, positron emission tomography and bone scintigraphy. Erdheim-Chester illness was revealed by a bone biopsy. Especially when there is cardiac and cerebral involvement, Erdheim-Chester illness is a rare condition with a poor prognosis. Knowing the imaging characteristics of Erdheim-Chester disease may be helpful in understanding the radiological results of many organs affected by the disease as described and discussed in the current case report.
    Language English
    Publishing date 2023-03-26
    Publishing country Netherlands
    Document type Case Reports
    ZDB-ID 2406300-9
    ISSN 1930-0433
    ISSN 1930-0433
    DOI 10.1016/j.radcr.2023.02.063
    Database MEDical Literature Analysis and Retrieval System OnLINE

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