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Article: Quoi de neuf dans les malformations capillaires ?

Dompmartin, A

Annales de dermatologie et de venereologie

2018 Volume 145, Issue 8-9, Page(s) 475–476

Title translation	Latest developments in capillary malformations.
MeSH term(s)	Capillaries/abnormalities ; Humans ; Mitogen-Activated Protein Kinase Kinases/antagonists & inhibitors ; Molecular Targeted Therapy ; Mutation ; Proto-Oncogene Proteins B-raf/antagonists & inhibitors ; Receptor, EphB4/genetics ; Vascular Malformations/genetics ; Vascular Malformations/therapy
Chemical Substances	Receptor, EphB4 (EC 2.7.10.1) ; Proto-Oncogene Proteins B-raf (EC 2.7.11.1) ; Mitogen-Activated Protein Kinase Kinases (EC 2.7.12.2)
Language	French
Publishing date	2018-07-26
Publishing country	France
Document type	Editorial
ZDB-ID	391805-1
ISSN	2214-5451 ; 0151-9638
ISSN (online)	2214-5451
ISSN	0151-9638
DOI	10.1016/j.annder.2018.07.003
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Article: Idiopathic facial aseptic granuloma in children: Management and long-term follow-up.

Da Silva Dias, V / Lafargue, O / Dompmartin, A

Annales de dermatologie et de venereologie

2023 Volume 150, Issue 3, Page(s) 173–179

Abstract: Aims: The primary objective was to study long-term outcomes in children with idiopathic facial aseptic granuloma (IFAG). The secondary objectives were to describe the clinical polymorphism of this entity, the different therapeutic options, and the ... ...

Abstract	Aims: The primary objective was to study long-term outcomes in children with idiopathic facial aseptic granuloma (IFAG). The secondary objectives were to describe the clinical polymorphism of this entity, the different therapeutic options, and the occurrence of rosacea in this population. Methods: We selected patients with a clinical diagnosis of IFAG seen in two different hospitals in Normandy between March 2016 and February 2021, and we collected clinical and therapeutic data from computerized medical records. A remote consultation based on recent photographs was performed to collect new data, and the children's parents were asked to complete a questionnaire between February and August 2021. Results: Ten children were included in this study. Nine patients presented with a single red to purplish nodule. One patient presented multiple papulopustular plaques. IFAG healed spontaneously without major sequelae, and this outcome was not influenced by any treatments. During follow-up, two patients developed childhood rosacea. Conclusion: Although some clinical heterogeneity exists, early diagnosis and follow-up of IFAG is necessary to avoid unnecessary topical or systemic antibiotic treatments that do not shorten the disease course. IFAG appears to be a possible mode of entry for infantile rosacea.
MeSH term(s)	Humans ; Child ; Follow-Up Studies ; Connective Tissue Diseases ; Administration, Cutaneous ; Anti-Bacterial Agents/therapeutic use ; Disease Progression ; Rosacea/complications ; Rosacea/diagnosis ; Rosacea/therapy
Chemical Substances	Anti-Bacterial Agents
Language	English
Publishing date	2023-05-30
Publishing country	France
Document type	Journal Article
ZDB-ID	391805-1
ISSN	2214-5451 ; 0151-9638
ISSN (online)	2214-5451
ISSN	0151-9638
DOI	10.1016/j.annder.2023.02.005
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Article ; Online: Efficacy, tolerance and acceptability of pulsed dye laser on facial and neckline telangiectasias in systemic scleroderma: a prospective open-label monocentric study in 21 patients.

Kottler, D / Dupechez, L / Martin Silva, N / Boutemy, J / Dumont, A / Maigné, G / Aouba, A / Dompmartin, A

Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology

2024 Volume 25, Issue 5-8, Page(s) 77–85

Abstract: Facial and neckline telangiectasias have an underestimated yet important impact on quality of life of patients with systemic scleroderma (SSc). This monocentric, prospective, open-label, intra-patient comparative study was conducted in 21 consecutive ... ...

Abstract	Facial and neckline telangiectasias have an underestimated yet important impact on quality of life of patients with systemic scleroderma (SSc). This monocentric, prospective, open-label, intra-patient comparative study was conducted in 21 consecutive patients with SSc. Patients underwent 4 sessions of PDL 8 weeks apart. A final quadruple assessment was performed by several raters 2 months after the last session, based on the following criteria: change in telangiectasia number; subjective improvement score (LINKERT scale); impact on the quality of life (QoL; SKINDEX score); visual analog pain scale; adverse effects (AEs), including treatment discontinuation for PDL-induced purpura and patient satisfaction. The mean telangiectasia number decreased by 5 (32%) at the end of the protocol. Eighteen patients (85.7%) reported an improvement or a strong improvement, versus 73.81% for the expert committee. Immediate session pain (mean = 3.4/10) was slightly less than overall pain (mean = 4.6/10). Ten patients (47%) experienced at least one AE (oozing/crusts, edema, epidermal blistering), including PDL-induced purpura in 3 patients (14%). AEs were mostly transient (<1 week) and mild (CTCAE grade 1). All QoL parameters improved after treatment, and 85% of patients were satisfied.
MeSH term(s)	Humans ; Lasers, Dye/adverse effects ; Pain ; Prospective Studies ; Purpura ; Quality of Life ; Scleroderma, Systemic/complications ; Telangiectasis/etiology ; Telangiectasis/therapy ; Treatment Outcome
Language	English
Publishing date	2024-02-19
Publishing country	England
Document type	Clinical Trial ; Journal Article
ZDB-ID	2146360-8
ISSN	1476-4180 ; 1476-4172
ISSN (online)	1476-4180
ISSN	1476-4172
DOI	10.1080/14764172.2024.2313472
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Article ; Online: Interest of frozen section procedure in skin tumors other than melanoma.

Petitjean, Clément / Bénateau, Hervé / Veyssière, Alexis / Morello, Remi / Dompmartin, Anne / Garmi, Rachid

Journal of plastic, reconstructive & aesthetic surgery : JPRAS

2023 Volume 84, Page(s) 377–384

Abstract: Background: Skin tumors are common. Recommended treatment in most cases is surgery, with margins adapted. Except in the case of simple resection and suture, it is necessary to know the status of the margins before reconstructing the defect. A one-stage ... ...

Abstract	Background: Skin tumors are common. Recommended treatment in most cases is surgery, with margins adapted. Except in the case of simple resection and suture, it is necessary to know the status of the margins before reconstructing the defect. A one-stage technique is possible with frozen section analysis, which gives the surgeon an intraoperative assessment of resection quality. The aim of our work is to study the reliability of the frozen section procedure. Method: A retrospective study included 689 patients who underwent surgery for skin tumor (excluding melanoma) between January 2011 and December 2019 at the University Hospital of Caen, France. Results: In 639 patients (92.75%), the frozen section analysis found healthy margins. There were 21 cases of discrepancy between the frozen section analysis and final histology. Infiltrating and scleroderma-like basal cell carcinomas showed a significantly higher frequency of affected margins on frozen section analysis (p < 0.001). The tumor size and location played a significant role in the margin status. Conclusion: In our department, the frozen section procedure is the reference examination indicating immediate flap reconstruction. The present study demonstrated its interest and overall reliability. However, it is to be used according to histologic type, size, and location.
MeSH term(s)	Humans ; Frozen Sections/methods ; Retrospective Studies ; Reproducibility of Results ; Skin Neoplasms/surgery ; Skin Neoplasms/pathology ; Melanoma/surgery
Language	English
Publishing date	2023-06-20
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	2217750-4
ISSN	1878-0539 ; 1748-6815 ; 0007-1226
ISSN (online)	1878-0539
ISSN	1748-6815 ; 0007-1226
DOI	10.1016/j.bjps.2023.06.030
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Article: Classification des anomalies vasculaires.

Dompmartin, A

Annales de dermatologie et de venereologie

2013 Volume 140, Issue 5, Page(s) 337–339

Title translation	Classification of vascular anomalies.
MeSH term(s)	Arteriovenous Malformations/classification ; Arteriovenous Malformations/diagnosis ; Arteriovenous Malformations/physiopathology ; Blood Vessels/abnormalities ; Diagnosis, Differential ; Gastrointestinal Neoplasms/diagnosis ; Glucose Transporter Type 1/genetics ; Glucose Transporter Type 1/metabolism ; Hemangioendothelioma/diagnosis ; Hemangioendothelioma/metabolism ; Hemangioma/classification ; Hemangioma/complications ; Hemangioma/metabolism ; Hemangioma, Capillary/classification ; Hemangioma, Capillary/congenital ; Hemangioma, Capillary/embryology ; Humans ; Infant, Newborn ; Kasabach-Merritt Syndrome/diagnosis ; Kasabach-Merritt Syndrome/etiology ; Kasabach-Merritt Syndrome/metabolism ; Lymphatic Abnormalities/classification ; Lymphatic Abnormalities/diagnosis ; Lymphatic Abnormalities/genetics ; Lymphatic Abnormalities/pathology ; Neoplasms, Vascular Tissue/classification ; Neoplasms, Vascular Tissue/diagnosis ; Neoplasms, Vascular Tissue/genetics ; Neoplasms, Vascular Tissue/pathology ; Nevus, Blue/diagnosis ; Remission, Spontaneous ; Sarcoma, Kaposi/diagnosis ; Sarcoma, Kaposi/metabolism ; Skin Neoplasms/classification ; Skin Neoplasms/complications ; Skin Neoplasms/congenital ; Skin Neoplasms/diagnosis ; Skin Neoplasms/metabolism ; Syndrome ; Vascular Malformations/classification ; Vascular Malformations/diagnosis ; Vascular Malformations/genetics ; Vascular Malformations/pathology
Chemical Substances	Glucose Transporter Type 1 ; SLC2A1 protein, human
Language	French
Publishing date	2013-05
Publishing country	France
Document type	Editorial
ZDB-ID	391805-1
ISSN	2214-5451 ; 0151-9638
ISSN (online)	2214-5451
ISSN	0151-9638
DOI	10.1016/j.annder.2013.02.002
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Article: Cardiovascular Immunotoxicity Associated with Immune Checkpoint Inhibitors in Metastatic Melanoma.

L'Orphelin, Jean-Matthieu / Dollalille, Charles / Akroun, Julia / Alexandre, Joachim / Dompmartin, Anne

Cancers

2023 Volume 15, Issue 7

Abstract: Background: Checkpoint inhibitors, such as PD-1 inhibitors (nivolumab, pembrolizumab) and anti-CTLA-4 (CD152) (ipilimumab), are widely used in metastatic melanoma, and most immune-related adverse events are known. Several cardiovascular AEs (CVAEs) ... ...

Abstract	Background: Checkpoint inhibitors, such as PD-1 inhibitors (nivolumab, pembrolizumab) and anti-CTLA-4 (CD152) (ipilimumab), are widely used in metastatic melanoma, and most immune-related adverse events are known. Several cardiovascular AEs (CVAEs) associated with immune checkpoint inhibitor exposure have been reported in post-marketing surveillance studies and represent major issues for patients with melanoma during and after cancer treatment. Data on CVAES induced by immune checkpoint inhibitors in melanoma, especially incidence and risk factors, are lacking. Methods: A systematic review of the literature up to 31 August 2020 was performed in Medline, the Cochrane Central Register of Controlled Trials (CENTRAL), and the ClinicalTrials.gov register according to prespecified selection criteria from inception to 7 April 2020. Statistics were performed on 3289 patients from five randomized clinical trials on melanoma. Results: Patients with melanoma treated with immune checkpoint inhibitors had a significant risk of presenting dyslipidemia (Peto OR: 4.74, 95% CI: 2.16-10.41, Conclusions: Our study underlines that checkpoint inhibitors used for melanoma increase CVAEs, especially dyslipidemia, which could pave the way to chronic inflammatory processes, atherosclerosis, and, finally, ischemic cardiopathy. These cardiovascular adverse events could be acute or delayed, justifying the monitoring of lipidic biology and a baseline cardiology consultation.
Language	English
Publishing date	2023-04-06
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2527080-1
ISSN	2072-6694
ISSN	2072-6694
DOI	10.3390/cancers15072170
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Article: A case report of anti-P200 pemphigoid following COVID-19 vaccination.

Bailly-Caillé, Barbara / Jouen, Fabienne / Dompmartin, Anne / Morice, Cécile

JAAD case reports

2022 Volume 23, Page(s) 83–86

Language	English
Publishing date	2022-03-15
Publishing country	United States
Document type	Case Reports
ZDB-ID	2834220-3
ISSN	2352-5126
ISSN	2352-5126
DOI	10.1016/j.jdcr.2022.03.011
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Article: Larva migrans ankylostomienne.

Da Silva Dias, V / Picard, C / Dompmartin, A

Annales de dermatologie et de venereologie

2020 Volume 147, Issue 5, Page(s) 400–402

Title translation	Cutaneous larva migrans.
MeSH term(s)	Administration, Oral ; Administration, Topical ; Animals ; Anthelmintics/therapeutic use ; Diagnosis, Differential ; Humans ; Larva Migrans/diagnosis ; Larva Migrans/drug therapy ; Larva Migrans/epidemiology ; Larva Migrans/physiopathology ; Travel ; Tropical Climate ; Zoonoses
Chemical Substances	Anthelmintics
Language	French
Publishing date	2020-03-30
Publishing country	France
Document type	Journal Article ; Review
ZDB-ID	391805-1
ISSN	2214-5451 ; 0151-9638
ISSN (online)	2214-5451
ISSN	0151-9638
DOI	10.1016/j.annder.2020.02.006
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Article: Un cas de papillomatose confluente et réticulée de Gougerot et Carteaud associé à un diabète de type MODY.

Cesaire, L / Kauffmann, D / Comoz, F / Dompmartin, A

Annales de dermatologie et de venereologie

2020 Volume 147, Issue 3, Page(s) 233–235

Title translation	A case of reticulated papillomatosis and maturity-onset diabetes of the young (MODY).
MeSH term(s)	Adolescent ; Diabetes Complications/complications ; Diabetes Complications/pathology ; Diabetes Mellitus, Type 2/complications ; Female ; Humans ; Papilloma/complications ; Papilloma/pathology ; Skin Neoplasms/complications ; Skin Neoplasms/pathology
Language	French
Publishing date	2020-02-07
Publishing country	France
Document type	Case Reports ; Journal Article
ZDB-ID	391805-1
ISSN	2214-5451 ; 0151-9638
ISSN (online)	2214-5451
ISSN	0151-9638
DOI	10.1016/j.annder.2019.11.004
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Article: Syndrome de fuite capillaire observé sous acitrétine : un cas et revue de la littérature.

Ezine, E / Pedailles, S / Dompmartin, A / Morice, C

Annales de dermatologie et de venereologie

2020 Volume 147, Issue 8-9, Page(s) 535–541

Abstract: Background: Retinoids are widely used in dermatology. Adverse effects are frequent and require clinical and laboratory monitoring. Herein we report the case of a patient with secondary capillary leak syndrome (SCLS) associated with acitretin. We then ... ...

Title translation	Acitretin-induced capillary leak syndrome: Case report and literature review.
Abstract	Background: Retinoids are widely used in dermatology. Adverse effects are frequent and require clinical and laboratory monitoring. Herein we report the case of a patient with secondary capillary leak syndrome (SCLS) associated with acitretin. We then present a review of the literature on systemic retinoids and SFCS. Patients and methods: A 57-year-old patient consulted following the onset of severe type I pityriasis rubra pilaris. Treatment was initiated comprising topical corticosteroids combined with acitretin at a dose of 0.5mg/kg/day. On the eighth day, voluminous edema appeared, accompanied by weight gain of 8kg in 48h and hypotension. The laboratory assessment showed hypoalbuminemia and hemoconcentration. Acitretin-induced SCLS was diagnosed based on the triple signs of hemoconcentration, hypoalbuminemia and hypotension, as well as rapid improvement following discontinuation of acitretin. Discussion: We collected 7 published clinical cases between 1981 and 2018, including our own case report. Retinoids were indicated only in severe cutaneous diseases. The mean time to onset of SLCS is 9.8 days, with a return to normal 17 days after discontinuation of retinoids. Capillary leak syndrome is a rare and under-diagnosed clinical-laboratory syndrome that must be recognized in order to avoid potentially fatal inappropriate management. It is a rare adverse effect of retinoids used in dermatology and the pathophysiology remains unclear.
MeSH term(s)	Acitretin/adverse effects ; Capillary Leak Syndrome/chemically induced ; Female ; Humans ; Middle Aged
Chemical Substances	Acitretin (LCH760E9T7)
Language	French
Publishing date	2020-07-08
Publishing country	France
Document type	Case Reports ; Journal Article ; Review
ZDB-ID	391805-1
ISSN	2214-5451 ; 0151-9638
ISSN (online)	2214-5451
ISSN	0151-9638
DOI	10.1016/j.annder.2020.04.021
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