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  1. Article ; Online: Corticosteroids for severe community-acquired pneumonia: a story without an ending.

    Rochwerg, Bram

    Intensive care medicine

    2022  Volume 48, Issue 8, Page(s) 1053–1055

    MeSH term(s) Adrenal Cortex Hormones/therapeutic use ; Community-Acquired Infections/drug therapy ; Humans ; Pneumonia/drug therapy
    Chemical Substances Adrenal Cortex Hormones
    Language English
    Publishing date 2022-05-13
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 80387-x
    ISSN 1432-1238 ; 0340-0964 ; 0342-4642 ; 0935-1701
    ISSN (online) 1432-1238
    ISSN 0340-0964 ; 0342-4642 ; 0935-1701
    DOI 10.1007/s00134-022-06699-w
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    Zs.A 1089: Show issues Location:
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  2. Article ; Online: Fluid Therapy in Sepsis: Does It Matter How Much?

    Silversides, Jonathan A / Rochwerg, Bram

    Chest

    2023  Volume 164, Issue 4, Page(s) 812–813

    MeSH term(s) Humans ; Fluid Therapy/methods ; Sepsis/therapy
    Language English
    Publishing date 2023-10-05
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 1032552-9
    ISSN 1931-3543 ; 0012-3692
    ISSN (online) 1931-3543
    ISSN 0012-3692
    DOI 10.1016/j.chest.2023.05.027
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    Ui III Zs.45: Show issues Location:
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    Zs.MO 349: Show issues

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  3. Article ; Online: Mind the gap: understanding the discordance between the ATS and ESICM ARDS guidelines-the ATS perspective.

    Sahetya, Sarina K / Rochwerg, Bram / Fan, Eddy

    Intensive care medicine

    2024  

    Language English
    Publishing date 2024-05-06
    Publishing country United States
    Document type Editorial
    ZDB-ID 80387-x
    ISSN 1432-1238 ; 0340-0964 ; 0342-4642 ; 0935-1701
    ISSN (online) 1432-1238
    ISSN 0340-0964 ; 0342-4642 ; 0935-1701
    DOI 10.1007/s00134-024-07431-6
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    Zs.A 1089: Show issues Location:
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  4. Article ; Online: The authors reply.

    Sharif, Sameer / Rochwerg, Bram

    Critical care medicine

    2022  Volume 50, Issue 12, Page(s) e810–e811

    Language English
    Publishing date 2022-11-17
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 197890-1
    ISSN 1530-0293 ; 0090-3493
    ISSN (online) 1530-0293
    ISSN 0090-3493
    DOI 10.1097/CCM.0000000000005665
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    Zs.A 1261: Show issues Location:
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  5. Article ; Online: Ventilator Weaning and Extubation.

    Burns, Karen E A / Rochwerg, Bram / Seely, Andrew J E

    Critical care clinics

    2024  Volume 40, Issue 2, Page(s) 391–408

    Abstract: Increasing evidence supports specific approaches to liberate patients from invasive ventilation including the use of liberation protocols, inspiratory assistance during spontaneous breathing trials (SBTs), early extubation of patients with chronic ... ...

    Abstract Increasing evidence supports specific approaches to liberate patients from invasive ventilation including the use of liberation protocols, inspiratory assistance during spontaneous breathing trials (SBTs), early extubation of patients with chronic obstructive pulmonary disease to noninvasive ventilation, and prophylactic use of noninvasive support strategies after extubation. Additional research is needed to elucidate the best criteria to identify patients who are ready to undergo an SBT and to inform optimal screening frequency, the best SBT technique and duration, extubation assessments, and extubation decision-making. Additional clarity is also needed regarding the optimal timing to measure and report extubation success.
    MeSH term(s) Humans ; Ventilator Weaning ; Airway Extubation ; Noninvasive Ventilation ; Pulmonary Disease, Chronic Obstructive/therapy
    Language English
    Publishing date 2024-02-06
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1006423-0
    ISSN 1557-8232 ; 0749-0704
    ISSN (online) 1557-8232
    ISSN 0749-0704
    DOI 10.1016/j.ccc.2024.01.007
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    Se 990: Show issues Location:
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  6. Article ; Online: Providing expert guidance in the evidence-based medicine era?

    Rochwerg, Bram

    Canadian journal of anaesthesia = Journal canadien d'anesthesie

    2019  Volume 66, Issue 4, Page(s) 356–359

    Title translation Fournir des conseils d’expert à l’ère de la médecine fondée sur des données probantes?
    MeSH term(s) Canada ; Consensus ; Evidence-Based Medicine ; Humans ; Social Responsibility ; Tissue Donors
    Language English
    Publishing date 2019-01-03
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 91002-8
    ISSN 1496-8975 ; 0832-610X
    ISSN (online) 1496-8975
    ISSN 0832-610X
    DOI 10.1007/s12630-018-01282-8
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    Zs.A 109: Show issues Location:
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  7. Article ; Online: In COVID-19, escalated- vs. prophylactic-dose anticoagulation does not reduce mortality and increases major bleeding.

    Chaudhuri, Dipayan / Rochwerg, Bram

    Annals of internal medicine

    2022  Volume 175, Issue 2, Page(s) JC18

    Abstract: Source citation: Ortega-Paz L, Galli M, Capodanno D, et al. ...

    Abstract Source citation: Ortega-Paz L, Galli M, Capodanno D, et al.
    MeSH term(s) Anticoagulants/administration & dosage ; Anticoagulants/adverse effects ; COVID-19 ; Hemorrhage/chemically induced ; Humans ; SARS-CoV-2
    Chemical Substances Anticoagulants
    Language English
    Publishing date 2022-02-01
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 336-0
    ISSN 1539-3704 ; 0003-4819
    ISSN (online) 1539-3704
    ISSN 0003-4819
    DOI 10.7326/J21-0021
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    Ua VI Zs.178/2: Show issues Location:
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  8. Article ; Online: Corticosteroids in Community-Acquired Pneumonia: In or Out?

    Pitre, Tyler / Rochwerg, Bram / Zeraatkar, Dena

    Chest

    2023  Volume 163, Issue 1, Page(s) e47–e48

    MeSH term(s) Humans ; Adrenal Cortex Hormones/therapeutic use ; Pneumonia/drug therapy ; Community-Acquired Infections/drug therapy
    Chemical Substances Adrenal Cortex Hormones
    Language English
    Publishing date 2023-01-10
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 1032552-9
    ISSN 1931-3543 ; 0012-3692
    ISSN (online) 1931-3543
    ISSN 0012-3692
    DOI 10.1016/j.chest.2022.09.036
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    Ui III Zs.45: Show issues Location:
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  9. Article ; Online: In adults hospitalized with COVID-19, adding baricitinib vs. dexamethasone to remdesivir did not differ for MV-free survival.

    Tran, Alexandre / Rochwerg, Bram

    Annals of internal medicine

    2022  Volume 175, Issue 10, Page(s) JC115

    Abstract: Source citation: Wolfe CR, Tomashek KM, Patterson TF, et al. ...

    Abstract Source citation: Wolfe CR, Tomashek KM, Patterson TF, et al.
    MeSH term(s) Adenosine Monophosphate/analogs & derivatives ; Adult ; Alanine/analogs & derivatives ; Azetidines ; COVID-19/drug therapy ; Dexamethasone/therapeutic use ; Double-Blind Method ; Humans ; Purines ; Pyrazoles ; Sulfonamides
    Chemical Substances Azetidines ; Purines ; Pyrazoles ; Sulfonamides ; remdesivir (3QKI37EEHE) ; Adenosine Monophosphate (415SHH325A) ; Dexamethasone (7S5I7G3JQL) ; baricitinib (ISP4442I3Y) ; Alanine (OF5P57N2ZX)
    Language English
    Publishing date 2022-10-04
    Publishing country United States
    Document type Journal Article ; Randomized Controlled Trial ; Comment
    ZDB-ID 336-0
    ISSN 1539-3704 ; 0003-4819
    ISSN (online) 1539-3704
    ISSN 0003-4819
    DOI 10.7326/J22-0074
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  10. Article ; Online: High-Flow Nasal Cannula Compared With Noninvasive Positive Pressure Ventilation in Acute Hypoxic Respiratory Failure: A Systematic Review and Meta-Analysis.

    Chaudhuri, Dipayan / Trivedi, Vatsal / Lewis, Kimberley / Rochwerg, Bram

    Critical care explorations

    2023  Volume 5, Issue 4, Page(s) e0892

    Abstract: To evaluate the efficacy and cost-effectiveness of high-flow nasal cannula (HFNC) when compared with noninvasive positive pressure ventilation (NIPPV) in patients with acute hypoxic respiratory failure (AHRF).: Data sources: We performed a ... ...

    Abstract To evaluate the efficacy and cost-effectiveness of high-flow nasal cannula (HFNC) when compared with noninvasive positive pressure ventilation (NIPPV) in patients with acute hypoxic respiratory failure (AHRF).
    Data sources: We performed a comprehensive search of MEDLINE, Embase, CINAHL, the Cochrane library, and the international Health Technology Assessment database from inception to September 14, 2022.
    Study selection: We included randomized control studies that compared HFNC to NIPPV in adult patients with AHRF. For clinical outcomes, we included only parallel group and crossover randomized control trials (RCTs). For economic outcomes, we included any study design that evaluated cost-effectiveness, cost-utility, or cost benefit analyses.
    Data extraction: Clinical outcomes of interest included intubation, mortality, ICU and hospital length of stay (LOS), and patient-reported dyspnea. Economic outcomes of interest included costs, cost-effectiveness, and cost-utility.
    Data synthesis: We included nine RCTs (
    Conclusions: HFNC and NIPPV may be similarly effective at reducing the need for intubation with an uncertain effect on mortality in hospitalized patients with hypoxemic respiratory failure. More research evaluating different interfaces in varying clinical contexts is needed to improve generalizability and precision of findings.
    Language English
    Publishing date 2023-03-28
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 2639-8028
    ISSN (online) 2639-8028
    DOI 10.1097/CCE.0000000000000892
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