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  1. Article ; Online: Editorial: Monitoring patients in the ICU in 2022.

    Wiener-Kronish, Jeanine P

    Current opinion in critical care

    2022  Volume 28, Issue 3, Page(s) 290–291

    MeSH term(s) Humans ; Intensive Care Units ; Monitoring, Physiologic
    Language English
    Publishing date 2022-03-09
    Publishing country United States
    Document type Editorial
    ZDB-ID 1235629-3
    ISSN 1531-7072 ; 1070-5295
    ISSN (online) 1531-7072
    ISSN 1070-5295
    DOI 10.1097/MCC.0000000000000938
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Roles for Anesthesiologists in the Future of Medicine in the United States.

    Evers, Alex S / Wiener-Kronish, Jeanine P

    Anesthesia and analgesia

    2022  Volume 134, Issue 2, Page(s) 231–233

    MeSH term(s) Anesthesiologists ; Anesthesiology ; Humans ; United States
    Language English
    Publishing date 2022-01-12
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 80032-6
    ISSN 1526-7598 ; 0003-2999
    ISSN (online) 1526-7598
    ISSN 0003-2999
    DOI 10.1213/ANE.0000000000005852
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Dose-dependent relationship between SGLT2 inhibitor hold time and risk for postoperative anion gap acidosis: a single-centre retrospective analysis.

    Steinhorn, Benjamin / Wiener-Kronish, Jeanine

    British journal of anaesthesia

    2023  Volume 131, Issue 4, Page(s) 682–686

    Abstract: ... between decreased hold time and postoperative anion gap (P<0.001 in a univariable analysis; -0.43, 95 ... confidence interval [-0.76 to -0.11] change in anion gap per day held, P=0.01 in a multivariable analysis ...

    Abstract Background: Use of sodium-glucose transporter-2 (SGLT2) inhibitors has dramatically increased over the past decade. This medication class predisposes patients to euglycaemic diabetic ketoacidosis, particularly during times of physiologic stress, including fasting and surgery. Beyond case reports and series, a systematic description of perioperative metabolic effects of SGLT2 inhibitors is lacking.
    Methods: We examined the degree of anion gap acidosis, controlling for non-ketone anions, in patients undergoing surgery at Massachusetts General Hospital in 2016-22. We constructed a multivariable regression model incorporating known non-ketone contributors to the postoperative anion gap (albumin, lactate, estimated glomerular filtration rate, and preoperative anion gap), hold time, and interaction terms between hold time and three previously suggested risk factors for euglycaemic diabetic ketoacidosis: emergency surgery, cardiac surgery, and insulin use.
    Results: In 463 patients on SGLT2 inhibitors, we observed a strong association between decreased hold time and postoperative anion gap (P<0.001 in a univariable analysis; -0.43, 95% confidence interval [-0.76 to -0.11] change in anion gap per day held, P=0.01 in a multivariable analysis). A significant interaction between hold time and emergency surgery was observed, whereas there was no apparent interaction with insulin use or cardiac surgery.
    Conclusions: These findings provide the first evidence that an anion gap acidosis, likely from ketoacids, develops in all patients who do not hold SGLT2 inhibitors before surgery rather than in an idiosyncratic few. If an SGLT2 inhibitor is unable to be stopped, postoperative monitoring of anion gap and serum ketones can help detect clinically significant euglycaemic diabetic ketoacidosis, particularly in those undergoing emergency surgery.
    MeSH term(s) Humans ; Sodium-Glucose Transporter 2 Inhibitors/adverse effects ; Diabetic Ketoacidosis/chemically induced ; Diabetic Ketoacidosis/diagnosis ; Acid-Base Equilibrium ; Retrospective Studies ; Acidosis/chemically induced ; Insulins/therapeutic use ; Diabetes Mellitus, Type 2/complications ; Diabetes Mellitus, Type 2/drug therapy
    Chemical Substances Sodium-Glucose Transporter 2 Inhibitors ; Insulins
    Language English
    Publishing date 2023-08-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 80074-0
    ISSN 1471-6771 ; 0007-0912
    ISSN (online) 1471-6771
    ISSN 0007-0912
    DOI 10.1016/j.bja.2023.06.063
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Wearables alone will not eliminate failure to rescue.

    Wiener-Kronish, Jeanine P / Bonnici, Timothy

    BJA open

    2022  Volume 2, Page(s) 100009

    Abstract: Surveys suggest that anaesthesiologists believe that continuous monitoring with wearables will lead to improved patient outcomes. However, evidence suggests that several critical factors, including timely recognition of physiological problems, the ... ...

    Abstract Surveys suggest that anaesthesiologists believe that continuous monitoring with wearables will lead to improved patient outcomes. However, evidence suggests that several critical factors, including timely recognition of physiological problems, the presence of a trained team to respond to the alerts, and that the alerts occur far in advance of the deterioration, are required before overall improvement can occur. Wearables alone will not change patients' outcomes, they must be implemented as part of a system change that takes advantage of the higher frequency observations that continuous monitoring provides.
    Language English
    Publishing date 2022-05-11
    Publishing country England
    Document type Editorial
    ISSN 2772-6096
    ISSN (online) 2772-6096
    DOI 10.1016/j.bjao.2022.100009
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  5. Book: New challenges in anesthesiology

    Wiener-Kronish, Jeanine P.

    new practice opportunities

    (Anesthesiology clinics of North America ; 17,2)

    1999  

    Author's details Jeanine P. Wiener-Kronish, guest ed
    Series title Anesthesiology clinics of North America ; 17,2
    Collection
    Language English
    Size XII S., S. 335 - 506 : graph. Darst.
    Publisher Saunders
    Publishing place Philadelphia u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT010625629
    Database Catalogue ZB MED Medicine, Health

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    Se 904 -17,2- verfügbar in Königswinter Königswinter

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  6. Article ; Online: Gender and Pathways to Leadership in Academic Anesthesiology: A Qualitative Content Analysis of US Chairpersons' Curricula Vitae.

    Lane-Fall, Meghan B / Hastie, Maya J / Kleid, Melanie / Yarabarla, Varun / Miltiades, Andrea N / Wiener-Kronish, Jeanine P / Pian-Smith, May C

    Anesthesia and analgesia

    2024  

    Abstract: ... years, P = .06), number of publications at the time the chair was assumed (101 vs 69, P = .28), or ...

    Abstract Background: Women are underrepresented in medicine and academic anesthesiology, and especially in leadership positions. We sought to characterize career achievement milestones of female versus male academic anesthesiology chairs to understand possible gender-related differences in pathways to leadership.
    Methods: We conducted a retrospective observational cross-sectional analysis. In November 2019, curricula vitae (CVs) were requested from then-current members of the US Association of Academic Anesthesiology Chairs. Data reflecting accomplishments up to the time of chair appointment were systematically extracted from CVs and analyzed using a mixed methods approach with qualitative content analysis supplemented by descriptive statistics and bivariate statistical testing. Missing data were not imputed.
    Results: Seventy-two CVs were received from eligible individuals (response rate 67.3%). The respondent sample was 12.5% women (n = 9), 87.5% men (n = 63), and no transgender or nonbinary people; this is similar to the known gender balance in anesthesiology chairs in the United States. No statistically significant differences in objective markers of academic achievement at the time of chair appointment were evident for female versus male chairs, including time elapsed between the first faculty appointment and assumption of the chair role (median 25 vs 18 years, P = .06), number of publications at the time the chair was assumed (101 vs 69, P = .28), or proportion who had ever held a National Institutes of Health (NIH) grant as principal investigator (44.4% vs 25.4%, 0.25). Four phenotypes of career paths were discernible in the data: the clinician-administrator, the educator, the investigator, and the well-rounded scholar; these did not differ by gender.
    Conclusions: Female chairpersons who were members of the Association of Academic Anesthesiology Chairs in the United States demonstrated similar patterns of academic achievement as compared to male chairpersons at the time the position of chair was assumed, suggesting that they were equally qualified for the role as compared to men. Four patterns of career achievements were evident in the chairperson group, suggesting multiple viable pathways to this leadership position.
    Language English
    Publishing date 2024-01-30
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80032-6
    ISSN 1526-7598 ; 0003-2999
    ISSN (online) 1526-7598
    ISSN 0003-2999
    DOI 10.1213/ANE.0000000000006821
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Evolving Role of Anesthesiology Intensivists in Cardiothoracic Critical Care.

    Shelton, Kenneth T / Wiener-Kronish, Jeanine P

    Anesthesiology

    2020  Volume 133, Issue 5, Page(s) 1120–1126

    MeSH term(s) Anesthesia, Cardiac Procedures/methods ; Anesthesia, Cardiac Procedures/trends ; Anesthesiology/methods ; Anesthesiology/trends ; Betacoronavirus ; COVID-19 ; Cardiopulmonary Resuscitation/methods ; Cardiopulmonary Resuscitation/trends ; Coronavirus Infections/prevention & control ; Coronavirus Infections/therapy ; Critical Care/methods ; Critical Care/trends ; Humans ; Intensive Care Units/trends ; Pandemics/prevention & control ; Pneumonia, Viral/prevention & control ; Pneumonia, Viral/therapy ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-06-04
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 269-0
    ISSN 1528-1175 ; 0003-3022
    ISSN (online) 1528-1175
    ISSN 0003-3022
    DOI 10.1097/ALN.0000000000003407
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.MO 199: Show issues

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  8. Book: Conscious sedation

    Wiener-Kronish, Jeanine P. / Gropper, Michael A.

    2001  

    Author's details Jeanine P. Wiener-Kronish ; Michael A. Biedler
    Keywords Conscious Sedation
    Language English
    Size X, 181 S.
    Publisher Hanley & Belfus
    Publishing place Philadelphia u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT012994653
    ISBN 1-56053-413-3 ; 978-1-56053-413-6
    Database Catalogue ZB MED Medicine, Health

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    2001 A 2133 order for loan Magazin

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  9. Article ; Online: Remote Surveillance Technologies: Realizing the Aim of Right Patient, Right Data, Right Time.

    Safavi, Kyan C / Driscoll, William / Wiener-Kronish, Jeanine P

    Anesthesia and analgesia

    2019  Volume 129, Issue 3, Page(s) 726–734

    Abstract: The convergence of multiple recent developments in health care information technology and monitoring devices has made possible the creation of remote patient surveillance systems that increase the timeliness and quality of patient care. More convenient, ... ...

    Abstract The convergence of multiple recent developments in health care information technology and monitoring devices has made possible the creation of remote patient surveillance systems that increase the timeliness and quality of patient care. More convenient, less invasive monitoring devices, including patches, wearables, and biosensors, now allow for continuous physiological data to be gleaned from patients in a variety of care settings across the perioperative experience. These data can be bound into a single data repository, creating so-called data lakes. The high volume and diversity of data in these repositories must be processed into standard formats that can be queried in real time. These data can then be used by sophisticated prediction algorithms currently under development, enabling the early recognition of patterns of clinical deterioration otherwise undetectable to humans. Improved predictions can reduce alarm fatigue. In addition, data are now automatically queriable on a real-time basis such that they can be fed back to clinicians in a time frame that allows for meaningful intervention. These advancements are key components of successful remote surveillance systems. Anesthesiologists have the opportunity to be at the forefront of remote surveillance in the care they provide in the operating room, postanesthesia care unit, and intensive care unit, while also expanding their scope to include high-risk preoperative and postoperative patients on the general care wards. These systems hold the promise of enabling anesthesiologists to detect and intervene upon changes in the clinical status of the patient before adverse events have occurred. Importantly, however, significant barriers still exist to the effective deployment of these technologies and their study in impacting patient outcomes. Studies demonstrating the impact of remote surveillance on patient outcomes are limited. Critical to the impact of the technology are strategies of implementation, including who should receive and respond to alerts and how they should respond. Moreover, the lack of cost-effectiveness data and the uncertainty of whether clinical activities surrounding these technologies will be financially reimbursed remain significant challenges to future scale and sustainability. This narrative review will discuss the evolving technical components of remote surveillance systems, the clinical use cases relevant to the anesthesiologist's practice, the existing evidence for their impact on patients, the barriers that exist to their effective implementation and study, and important considerations regarding sustainability and cost-effectiveness.
    MeSH term(s) Anesthesiology/economics ; Anesthesiology/methods ; Anesthesiology/standards ; Cost-Benefit Analysis/methods ; Cost-Benefit Analysis/standards ; Data Management/economics ; Data Management/methods ; Data Management/standards ; Humans ; Medical Informatics/economics ; Medical Informatics/methods ; Medical Informatics/standards ; Quality of Health Care/economics ; Quality of Health Care/standards ; Remote Sensing Technology/economics ; Remote Sensing Technology/methods ; Remote Sensing Technology/standards ; Time Factors
    Language English
    Publishing date 2019-06-18
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 80032-6
    ISSN 1526-7598 ; 0003-2999
    ISSN (online) 1526-7598
    ISSN 0003-2999
    DOI 10.1213/ANE.0000000000003948
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Book: Critical care handbook of the Massachusetts General Hospital

    Wiener-Kronish, Jeanine P

    2016  

    Abstract: This is a practical, multidisciplinary, clinically-oriented guide to all aspects of critical care written by the internationally renowned staff at MGH"-- ...

    Institution Massachusetts General Hospital,
    Author's details senior editor, Jeanine P. Wiener-Kronish ; associate editors, Aranya Bagchi [and four others]
    Abstract "This is a practical, multidisciplinary, clinically-oriented guide to all aspects of critical care written by the internationally renowned staff at MGH"--
    MeSH term(s) Critical Care ; Postoperative Complications
    Language English
    Size xxii, 640 pages :, illustrations ;, 21 cm
    Edition Sixth edition.
    Document type Book
    Note "Lippincott Williams and Wilkins handbook"--Cover.
    ISBN 9781451195101 ; 1451195109
    Database Catalogue of the US National Library of Medicine (NLM)

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