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  1. Article ; Online: Search for Evidence of Baryogenesis and Dark Matter in B^{+}→ψ_{D}+p Decays at BABAR.

    Lees, J P / Poireau, V / Tisserand, V / Grauges, E / Palano, A / Eigen, G / Brown, D N / Kolomensky, Yu G / Fritsch, M / Koch, H / Cheaib, R / Hearty, C / Mattison, T S / McKenna, J A / So, R Y / Blinov, V E / Buzykaev, A R / Druzhinin, V P / Kozyrev, E A /
    Kravchenko, E A / Serednyakov, S I / Skovpen, Yu I / Solodov, E P / Todyshev, K Yu / Lankford, A J / Dey, B / Gary, J W / Long, O / Eisner, A M / Lockman, W S / Panduro Vazquez, W / Chao, D S / Cheng, C H / Echenard, B / Flood, K T / Hitlin, D G / Li, Y / Lin, D X / Middleton, S / Miyashita, T S / Ongmongkolkul, P / Oyang, J / Porter, F C / Röhrken, M / Meadows, B T / Sokoloff, M D / Smith, J G / Wagner, S R / Bernard, D / Verderi, M / Bettoni, D / Bozzi, C / Calabrese, R / Cibinetto, G / Fioravanti, E / Garzia, I / Luppi, E / Santoro, V / Calcaterra, A / de Sangro, R / Finocchiaro, G / Martellotti, S / Patteri, P / Peruzzi, I M / Piccolo, M / Rotondo, M / Zallo, A / Passaggio, S / Patrignani, C / Shuve, B J / Lacker, H M / Bhuyan, B / Mallik, U / Chen, C / Cochran, J / Prell, S / Gritsan, A V / Arnaud, N / Davier, M / Le Diberder, F / Lutz, A M / Wormser, G / Lange, D J / Wright, D M / Coleman, J P / Hutchcroft, D E / Payne, D J / Touramanis, C / Bevan, A J / Di Lodovico, F / Cowan, G / Banerjee, Sw / Davis, C L / Denig, A G / Gradl, W / Griessinger, K / Hafner, A / Schubert, K R / Barlow, R J / Lafferty, G D / Cenci, R / Jawahery, A / Roberts, D A / Cowan, R / Robertson, S H / Seddon, R M / Neri, N / Palombo, F / Cremaldi, L / Godang, R / Summers, D J / De Nardo, G / Sciacca, C / Jessop, C P / LoSecco, J M / Honscheid, K / Gaz, A / Margoni, M / Simi, G / Simonetto, F / Stroili, R / Akar, S / Ben-Haim, E / Bomben, M / Bonneaud, G R / Calderini, G / Chauveau, J / Marchiori, G / Ocariz, J / Biasini, M / Manoni, E / Rossi, A / Batignani, G / Bettarini, S / Carpinelli, M / Casarosa, G / Chrzaszcz, M / Forti, F / Giorgi, M A / Lusiani, A / Oberhof, B / Paoloni, E / Rama, M / Rizzo, G / Walsh, J J / Zani, L / Smith, A J S / Anulli, F / Faccini, R / Ferrarotto, F / Ferroni, F / Pilloni, A / Bünger, C / Dittrich, S / Grünberg, O / Leddig, T / Voß, C / Waldi, R / Adye, T / Wilson, F F / Emery, S / Vasseur, G / Aston, D / Cartaro, C / Convery, M R / Dunwoodie, W / Ebert, M / Field, R C / Fulsom, B G / Graham, M T / Hast, C / Kim, P / Luitz, S / MacFarlane, D B / Muller, D R / Neal, H / Ratcliff, B N / Roodman, A / Sullivan, M K / Va'vra, J / Wisniewski, W J / Purohit, M V / Wilson, J R / Sekula, S J / Ahmed, H / Tasneem, N / Bellis, M / Burchat, P R / Puccio, E M T / Ernst, J A / Gorodeisky, R / Guttman, N / Peimer, D R / Soffer, A / Spanier, S M / Ritchie, J L / Izen, J M / Lou, X C / Bianchi, F / De Mori, F / Filippi, A / Lanceri, L / Vitale, L / Martinez-Vidal, F / Oyanguren, A / Albert, J / Beaulieu, A / Bernlochner, F U / King, G J / Kowalewski, R / Lueck, T / Miller, C / Nugent, I M / Roney, J M / Sobie, R J / Gershon, T J / Harrison, P F / Latham, T E / Wu, S L

    Physical review letters

    2023  Volume 131, Issue 20, Page(s) 201801

    Abstract: ... presents a search for B^{+}→ψ_{D}+p (and the charge conjugate) decays in e^{+}e^{-} annihilations at 10.58 ... A new dark sector antibaryon, denoted ψ_{D}, could be produced in decays of B mesons. This Letter ... in the range from 10^{-7}-10^{-5} are obtained at 90% confidence level for masses of 1.0D}}<4.3  GeV/c^ ...

    Abstract A new dark sector antibaryon, denoted ψ_{D}, could be produced in decays of B mesons. This Letter presents a search for B^{+}→ψ_{D}+p (and the charge conjugate) decays in e^{+}e^{-} annihilations at 10.58 GeV, using data collected in the BABAR experiment. Data corresponding to an integrated luminosity of 398  fb^{-1} are analyzed. No evidence for a signal is observed. Branching fraction upper limits in the range from 10^{-7}-10^{-5} are obtained at 90% confidence level for masses of 1.0<m_{ψ_{<mark>D}}<4.3  GeV/c^{2}. The result is also reinterpreted to provide the first limits on a supersymmetric model with R-parity violation and a light neutralino.
    Language English
    Publishing date 2023-12-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208853-8
    ISSN 1079-7114 ; 0031-9007
    ISSN (online) 1079-7114
    ISSN 0031-9007
    DOI 10.1103/PhysRevLett.131.201801
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Observation of a Charmed Baryon Decaying to D;{0}p at a Mass Near 2.94 GeV/c;{2}.

    Aubert, B / Barate, R / Bona, M / Boutigny, D / Couderc, F / Karyotakis, Y / Lees, J P / Poireau, V / Tisserand, V / Zghiche, A / Grauges, E / Palano, A / Pappagallo, M / Chen, J C / Qi, N D / Rong, G / Wang, P / Zhu, Y S / Eigen, G /
    Ofte, I / Stugu, B / Abrams, G S / Battaglia, M / Brown, D N / Button-Schafer, J / Cahn, R N / Charles, E / Day, C T / Gill, M S / Groysman, Y / Jacobsen, R G / Kadyk, J A / Kerth, L T / Kolomensky, Yu G / Kukartsev, G / Lynch, G / Mir, L M / Oddone, P J / Orimoto, T J / Pripstein, M / Roe, N A / Ronan, M T / Wenzel, W A / Barrett, M / Ford, K E / Harrison, T J / Hart, A J / Hawkes, C M / Morgan, S E / Watson, A T / Goetzen, K / Held, T / Koch, H / Lewandowski, B / Pelizaeus, M / Peters, K / Schroeder, T / Steinke, M / Boyd, J T / Burke, J P / Cottingham, W N / Walker, D / Cuhadar-Donszelmann, T / Fulsom, B G / Hearty, C / Knecht, N S / Mattison, T S / McKenna, J A / Khan, A / Kyberd, P / Saleem, M / Teodorescu, L / Blinov, V E / Bukin, A D / Druzhinin, V P / Golubev, V B / Onuchin, A P / Serednyakov, S I / Skovpen, Yu I / Solodov, E P / Yu Todyshev, K / Best, D S / Bondioli, M / Bruinsma, M / Chao, M / Curry, S / Eschrich, I / Kirkby, D / Lankford, A J / Lund, P / Mandelkern, M / Mommsen, R K / Roethel, W / Stoker, D P / Abachi, S / Buchanan, C / Foulkes, S D / Gary, J W / Long, O / Shen, B C / Wang, K / Zhang, L / Hadavand, H K / Hill, E J / Paar, H P / Rahatlou, S / Sharma, V / Berryhill, J W / Campagnari, C / Cunha, A / Dahmes, B / Hong, T M / Kovalskyi, D / Richman, J D / Beck, T W / Eisner, A M / Flacco, C J / Heusch, C A / Kroseberg, J / Lockman, W S / Nesom, G / Schalk, T / Schumm, B A / Seiden, A / Spradlin, P / Williams, D C / Wilson, M G / Albert, J / Chen, E / Dvoretskii, A / Hitlin, D G / Narsky, I / Piatenko, T / Porter, F C / Ryd, A / Samuel, A / Andreassen, R / Mancinelli, G / Meadows, B T / Sokoloff, M D / Blanc, F / Bloom, P C / Chen, S / Ford, W T / Hirschauer, J F / Kreisel, A / Nauenberg, U / Olivas, A / Ruddick, W O / Smith, J G / Ulmer, K A / Wagner, S R / Zhang, J / Chen, A / Eckhart, E A / Soffer, A / Toki, W H / Wilson, R J / Winklmeier, F / Zeng, Q / Altenburg, D D / Feltresi, E / Hauke, A / Jasper, H / Spaan, B / Brandt, T / Klose, V / Lacker, H M / Mader, W F / Nogowski, R / Petzold, A / Schubert, J / Schubert, K R / Schwierz, R / Sundermann, J E / Volk, A / Bernard, D / Bonneaud, G R / Grenier, P / Latour, E / Thiebaux, Ch / Verderi, M / Bard, D J / Clark, P J / Gradl, W / Muheim, F / Playfer, S / Robertson, A I / Xie, Y / Andreotti, M / Bettoni, D / Bozzi, C / Calabrese, R / Cibinetto, G / Luppi, E / Negrini, M / Petrella, A / Piemontese, L / Prencipe, E / Anulli, F / Baldini-Ferroli, R / Calcaterra, A / de Sangro, R / Finocchiaro, G / Pacetti, S / Patteri, P / Peruzzi, I M / Piccolo, M / Rama, M / Zallo, A / Buzzo, A / Capra, R / Contri, R / Lo Vetere, M / Macri, M M / Monge, M R / Passaggio, S / Patrignani, C / Robutti, E / Santroni, A / Tosi, S / Brandenburg, G / Chaisanguanthum, K S / Morii, M / Wu, J / Dubitzky, R S / Marks, J / Schenk, S / Uwer, U / Bhimji, W / Bowerman, D A / Dauncey, P D / Egede, U / Flack, R L / Gaillard, J R / Nash, J A / Nikolich, M B / Panduro Vazquez, W / Chai, X / Charles, M J / Mallik, U / Meyer, N T / Ziegler, V / Cochran, J / Crawley, H B / Dong, L / Eyges, V / Meyer, W T / Prell, S / Rosenberg, E I / Rubin, A E / Gristan, A V / Fritsch, M / Schott, G / Arnaud, N / Davier, M / Grosdidier, G / Höcker, A / Le Diberder, F / Lepeltier, V / Lutz, A M / Oyanguren, A / Pruvot, S / Rodier, S / Roudeau, P / Schune, M H / Stocchi, A / Wang, W F / Wormser, G / Cheng, C H / Lange, D J / Wright, D M / Chavez, C A / Forster, I J / Fry, J R / Gabathuler, E / Gamet, R / George, K A / Hutchcroft, D E / Payne, D J / Schofield, K C / Touramanis, C / Bevan, A J / Di Lodovico, F / Menges, W / Sacco, R / Brown, C L / Cowan, G / Flaecher, H U / Hopkins, D A / Jackson, P S / McMahon, T R / Ricciardi, S / Salvatore, F / Davis, C L / Allison, J / Barlow, N R / Barlow, R J / Chia, Y M / Edgar, C L / Kelly, M P / Lafferty, G D / Naisbit, M T / Williams, J C / Yi, J I / Chen, C / Hulsbergen, W D / Jawahery, A / Lae, C K / Roberts, D A / Simi, G / Blaylock, G / Dallapiccola, C / Hertzbach, S S / Li, X / Moore, T B / Saremi, S / Staengle, H / Willocq, S Y / Cowan, R / Koeneke, K / Sciolla, G / Sekula, S J / Spitznagel, M / Taylor, F / Yamamoto, R K / Kim, H / Patel, P M / Potter, C T / Robertson, S H / Lazzaro, A / Lombardo, V / Palombo, F / Bauer, J M / Cremaldi, L / Eschenburg, V / Godang, R / Kroeger, R / Reidy, J / Sanders, D A / Summers, D J / Zhao, H W / Brunet, S / Côté, D / Simard, M / Taras, P / Viaud, F B / Nicholson, H / Cavallo, N / De Nardo, G / Del Re, D / Fabozzi, F / Gatto, C / Lista, L / Monorchio, D / Paolucci, P / Piccolo, D / Sciacca, C / Baak, M / Bulten, H / Raven, G / Snoek, H L / Jessop, C P / Losecco, J M / Allmendinger, T / Benelli, G / Gan, K K / Honscheid, K / Hufnagel, D / Jackson, P D / Kagan, H / Kass, R / Pulliam, T / Rahimi, A M / Ter-Antonyan, R / Wong, Q K / Blout, N L / Brau, J / Frey, R / Igonkina, O / Lu, M / Rahmat, R / Sinev, N B / Strom, D / Strube, J / Torrence, E / Galeazzi, F / Gaz, A / Margoni, M / Morandin, M / Pompili, A / Posocco, M / Rotondo, M / Simonetto, F / Stroili, R / Voci, C / Benayoun, M / Chauveau, J / David, P / Del Buono, L / de la Vaissière, Ch / Hamon, O / Hartfiel, B L / John, M J J / Leruste, Ph / Malclès, J / Ocariz, J / Roos, L / Therin, G / Behera, P K / Gladney, L / Panetta, J / Biasini, M / Covarelli, R / Pioppi, M / Angelini, C / Batignani, G / Bettarini, S / Bucci, F / Calderini, G / Carpinelli, M / Cenci, R / Forti, F / Giorgi, M A / Lusiani, A / Marchiori, G / Mazur, M A / Morganti, M / Neri, N / Paoloni, E / Rizzo, G / Walsh, J / Haire, M / Judd, D / Wagoner, D E / Biesiada, J / Danielson, N / Elmer, P / Lau, Y P / Lu, C / Olsen, J / Smith, A J S / Telnov, A V / Bellini, F / Cavoto, G / D'Orazio, A / Di Marco, E / Faccini, R / Ferrarotto, F / Ferroni, F / Gaspero, M / Li Gioi, L / Mazzoni, M A / Morganti, S / Piredda, G / Polci, F / Safai Tehrani, F / Voena, C / Ebert, M / Schröder, H / Waldi, R / Adye, T / De Groot, N / Franek, B / Olaiya, E O / Wilson, F F / Emery, S / Gaidot, A / Ganzhur, S F / Hamel de Monchenault, G / Kozanecki, W / Legendre, M / Mayer, B / Vasseur, G / Yèche, Ch / Zito, M / Park, W / Purohit, M V / Weidemann, A W / Wilson, J R / Allen, M T / Aston, D / Bartoldus, R / Bechtle, P / Berger, N / Boyarski, A M / Claus, R / Coleman, J P / Convery, M R / Cristinziani, M / Dingfelder, J C / Dong, D / Dorfan, J / Dubois-Felsmann, G P / Dujmic, D / Dunwoodie, W / Field, R C / Glanzman, T / Gowdy, S J / Graham, M T / Halyo, V / Hast, C / Hyrn'ova, T / Innes, W R / Kelsey, M H / Kim, P / Kocian, M L / Leith, D W G S / Li, S / Libby, J / Luitz, S / Luth, V / Lynch, H L / Macfarlane, D B / Marsiske, H / Messner, R / Muller, D R / O'grady, C P / Ozcan, V E / Perazzo, A / Perl, M / Ratcliff, B N / Roodman, A / Salnikov, A A / Schindler, R H / Schwiening, J / Snyder, A / Stelzer, J / Su, D / Sullivan, M K / Suzuki, K / Swain, S K / Thompson, J M / Va'vra, J / van Bakel, N / Weaver, M / Weinstein, A J R / Wisniewski, W J / Wittgen, M / Wright, D H / Yarritu, A K / Yi, K / Young, C C / Burchat, P R / Edwards, A J / Majewski, S A / Petersen, B A / Roat, C / Wilden, L / Ahmed, S / Alam, M S / Bula, R / Ernst, J A / Jain, V / Pan, B / Saeed, M A / Wappler, F R / Zain, S B / Bugg, W / Krishnamurthy, M / Spanier, S M / Eckmann, R / Ritchie, J L / Satpathy, A / Schilling, C J / Schwitters, R F / Izen, J M / Kitayama, I / Lou, X C / Ye, S / Bianchi, F / Gallo, F / Gamba, D / Bomben, M / Bosisio, L / Cartaro, C / Cossutti, F / Della Ricca, G / Dittongo, S / Grancagnolo, S / Lanceri, L / Vitale, L / Azzolini, V / Martinez-Vidal, F / Banerjee, Sw / Bhuyan, B / Brown, C M / Fortin, D / Hamano, K / Kowalewski, R / Nugent, I M / Roney, J M / Sobie, R J / Back, J J / Harrison, P F / Latham, T E / Mohanty, G B / Band, H R / Chen, X / Cheng, B / Dasu, S / Datta, M / Eichenbaum, A M / Flood, K T / Hollar, J J / Johnson, J R / Kutter, P E / Li, H / Liu, R / Mellado, B / Mihalyi, A / Mohapatra, A K / Pan, Y / Pierini, M / Prepost, R / Tan, P / Wu, S L / Yu, Z / Neal, H

    Physical review letters

    2007  Volume 98, Issue 1, Page(s) 12001

    Abstract: A search for charmed baryons decaying to D(0)p reveals two states: the Lambdac(2880)+ baryon and ...

    Abstract A search for charmed baryons decaying to D(0)p reveals two states: the Lambdac(2880)+ baryon and a previously unobserved state at a mass of [2939.8+/-1.3(stat)+/-1.0(syst)] MeV/c2 and with an intrinsic width of [17.5+/-5.2(stat)+/-5.9(syst)] MeV. Consistent and significant signals are observed for the K(-)pi(+) and K(-)pi(+)pi(-)pi(+) decay modes of the D0 in 287 fb(-1) annihilation data recorded by the BABAR detector at a center-of-mass energy of 10.58 GeV. There is no evidence in the D+p spectrum of doubly charged partners. The mass and intrinsic width of the Lambdac(2880)+ baryon and relative yield of the two baryons are also measured.
    Language English
    Publishing date 2007-01-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208853-8
    ISSN 1079-7114 ; 0031-9007
    ISSN (online) 1079-7114
    ISSN 0031-9007
    DOI 10.1103/PhysRevLett.98.012001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Hormone Replacement Therapy in Post-Menopause Hormone-Dependent Gynecological Cancer Patients: A Narrative Review.

    Villa, Paola / Bounous, Valentina Elisabetta / Amar, Inbal Dona / Bernardini, Federica / Giorgi, Margherita / Attianese, Daniela / Ferrero, Annamaria / D'Oria, Marika / Scambia, Giovanni

    Journal of clinical medicine

    2024  Volume 13, Issue 5

    Abstract: Background: Advances in the treatment of gynecological cancer have led to improvements in survival but also an increase in menopausal symptoms, especially in young women with premature iatrogenic menopause.: Methods: A narrative review was performed ... ...

    Abstract Background: Advances in the treatment of gynecological cancer have led to improvements in survival but also an increase in menopausal symptoms, especially in young women with premature iatrogenic menopause.
    Methods: A narrative review was performed to clarify the possibility of prescribing hormone replacement therapy (HRT) after hormone-dependent gynecological cancers (ovarian cancer [OC], cervical adenocarcinoma [AC], and endometrial cancer [EC]).
    Results: HRT can be prescribed to patients with early-stage, grade I-II OC who experience bothersome menopausal symptoms non-responsive to alternative non-hormone therapy after optimal surgery. Caution should be exercised in administering HRT after serous borderline tumors and endometrioid OC, and HRT is not recommended in low-grade serous OC. HRT is not contraindicated in AC survivors. After surgery for EC, HRT can be prescribed in women with early-stage low-grade EC. There is not enough data to give indications to patients with advanced EC.
    Conclusions: HRT can be discussed with patients, evaluating the risks and benefits of hormone-dependent gynecological cancer. Counseling should be performed by gynecologic oncologists experienced in the management of these patients.
    Language English
    Publishing date 2024-03-01
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm13051443
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: A Tetranuclear Copper(II)/Calcium(II) Complex as Dual Chemosensor for Colorimetric and Fluorescent Detection of Non-Steroidal Anti-Inflammatory Drugs.

    Macedi, Eleonora / Giorgi, Luca / Formica, Mauro / Rossi, Patrizia / Paderni, Daniele / Paoli, Paola / Fusi, Vieri

    ChemPlusChem

    2023  Volume 88, Issue 5, Page(s) e202200364

    Abstract: The tetranuclear ... ...

    Abstract The tetranuclear Cu
    MeSH term(s) Calcium ; Copper ; Colorimetry ; Anti-Inflammatory Agents, Non-Steroidal ; Anions
    Chemical Substances Calcium (SY7Q814VUP) ; Copper (789U1901C5) ; Anti-Inflammatory Agents, Non-Steroidal ; Anions
    Language English
    Publishing date 2023-01-19
    Publishing country Germany
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 2192-6506
    ISSN (online) 2192-6506
    DOI 10.1002/cplu.202200364
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Environmentally friendly ZnO/Castor oil polyurethane composites for the gas-phase adsorption of acetic acid.

    Zuliani, Alessio / Bandelli, Damiano / Chelazzi, David / Giorgi, Rodorico / Baglioni, Piero

    Journal of colloid and interface science

    2022  Volume 614, Page(s) 451–459

    Abstract: Hypothesis: Acetic acid, a common pollutant present in museums and art galleries, can irreversibly damage works of art. Herein, a sustainable and scalable synthesis of zinc oxide-castor oil polyurethane hybrids (ZnO/COPs), to be used as acetic acid ... ...

    Abstract Hypothesis: Acetic acid, a common pollutant present in museums and art galleries, can irreversibly damage works of art. Herein, a sustainable and scalable synthesis of zinc oxide-castor oil polyurethane hybrids (ZnO/COPs), to be used as acetic acid removers in the preventive conservation of Cultural Heritage, is reported.
    Experiments: The adsorption capacities of ZnO/COPs were studied in saturated acetic acid atmosphere, at low acetic acid gas concentration, and inside a wooden crate (naturally emitting acetic acid) representative of those used in the storage deposits of museums and art collections.
    Findings: Upon exposure, acetic acid interacts with the castor oil polyurethane and diffuses to the surface of ZnO particles where is stably fixed as zinc acetate crystals. Zinc acetate domains form homogeneously on the surface and are distributed evenly within the ZnO/COPs, thanks to weak interactions between the polyurethane matrix and acetic acid that favour the transport of the acid up to reach the zinc oxide surfaces, resulting in a synergistic effect. The ZnO/COPs composites showed significantly enhanced adsorption capacities of acetic acid surpassing those of the activated carbon benchmark, with the advantage of being easily handled and movable, without the health issues and risks associated to the use of non-confined micro/nano-powders.
    MeSH term(s) Acetic Acid ; Adsorption ; Castor Oil/chemistry ; Polyurethanes/chemistry ; Zinc Oxide/chemistry
    Chemical Substances Polyurethanes ; Castor Oil (8001-79-4) ; Acetic Acid (Q40Q9N063P) ; Zinc Oxide (SOI2LOH54Z)
    Language English
    Publishing date 2022-01-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 241597-5
    ISSN 1095-7103 ; 0021-9797
    ISSN (online) 1095-7103
    ISSN 0021-9797
    DOI 10.1016/j.jcis.2022.01.123
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Platelet-Rich Plasma for Patients with Olfactory Dysfunction: Myth or Reality? A Systematic Review.

    Moffa, Antonio / Nardelli, Domiziana / Giorgi, Lucrezia / Di Giovanni, Simone / Carnuccio, Luca / Mangino, Carmen / Baptista, Peter / Vacca, Michele / Casale, Manuele

    Journal of clinical medicine

    2024  Volume 13, Issue 3

    Abstract: Background: With promising outcomes, platelet-rich plasma (PRP) has recently been suggested as a treatment for olfactory dysfunction (OD).: Methods: Clinical studies utilizing PRP in OD caused by COVID-19, trauma, anesthetic exposure, viral infection, ...

    Abstract Background: With promising outcomes, platelet-rich plasma (PRP) has recently been suggested as a treatment for olfactory dysfunction (OD).
    Methods: Clinical studies utilizing PRP in OD caused by COVID-19, trauma, anesthetic exposure, viral infection, and chronic rhinosinusitis were included in a systematic review.
    Results: Ten clinical studies were qualitatively analyzed. Six of these studies used the PRP for OD caused by COVID-19, one on OD after functional endoscopic sinus surgery, and three on post-infectious or post-trauma OD. The population included 531 patients, ranging in age from 15 to 63.
    Conclusion: The use of PRP may be a risk-free and efficient therapeutic option with very encouraging outcomes. Indeed, it enhances olfactory perception in patients who not only exhibit COVID-19 infection aftereffects, but also in those who have lost their sense of smell due to trauma, rhinosinusitis, rhinitis, or even surgery. To evaluate the PRP's therapeutic benefits in OD patients and to compare the efficacy of different therapeutic protocols with regard to treatment schedules, there is an urgent need for focused controlled trials.
    Language English
    Publishing date 2024-01-29
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm13030782
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Adsorption kinetics of acetic acid into ZnO/castor oil-derived polyurethanes.

    Zuliani, Alessio / Chelazzi, David / Mastrangelo, Rosangela / Giorgi, Rodorico / Baglioni, Piero

    Journal of colloid and interface science

    2022  Volume 632, Issue Pt A, Page(s) 74–86

    Abstract: Hypothesis: Materials and colloids science can provide significant contributions to the conservation of Cultural Heritage. Hybrid systems made of a castor oil-derived polymeric network and a disperse phase of zinc oxide particles (ZnO/COPs) can be more ... ...

    Abstract Hypothesis: Materials and colloids science can provide significant contributions to the conservation of Cultural Heritage. Hybrid systems made of a castor oil-derived polymeric network and a disperse phase of zinc oxide particles (ZnO/COPs) can be more effective absorbers of acetic acid (AcOH, a major pollutant harmful to artifacts in museums and art collections) than state-of-the-art materials, provided the acid uptake mechanism by the hybrids is elucidated and optimized. The starting hypothesis was that the polymer matrix might act as transporter, while acid adsorption would take place at the ZnO particles surface. The effect of particles size was expected to play a significant role.
    Experiments: The adsorption kinetics of the hybrids were studied in the 23-45˚C range, in comparison with activated charcoal, the benchmark employed by conservators. Morphological and fractal dimension of ZnO micro- and nano-particles in the hybrid networks were investigated and correlated to the adsorption kinetics.
    Findings: The presence of a two-steps mechanism for AcOH uptake by the hybrids was demonstrated for the first time: a combination of Fickian diffusion and Case-II transport occurs in the COP matrix, and adsorption dominates acid uptake (followed by neutralization) at the particles surface. This mechanism is likely key to explain the enhanced performances of the hybrids vs activated charcoal and state-of-the-art tools to remove AcOH. The hybrids have high uptake capacity, and lower activation energies for the removal process than materials where the uptake of acid relies solely on adsorption. The size of the ZnO particles contributes to the process, i.e. nanoparticles form smaller and ramified fractal clusters that are able to adsorb AcOH more effectively than microparticles. These insights demonstrated the efficacy of the novel hybrids in art conservation, where the control of minimal concentrations of VOCs is crucial for the preventive conservation of masterpieces, and can be useful to other fields where efficient capture of acetic acid is critical (food industry, textile dyeing/printing, etc.).
    MeSH term(s) Castor Oil ; Acetic Acid ; Zinc Oxide ; Polyurethanes ; Adsorption ; Charcoal ; Polymers
    Chemical Substances Castor Oil (8001-79-4) ; Acetic Acid (Q40Q9N063P) ; Zinc Oxide (SOI2LOH54Z) ; Polyurethanes ; Charcoal (16291-96-6) ; Polymers
    Language English
    Publishing date 2022-11-14
    Publishing country United States
    Document type Journal Article
    ZDB-ID 241597-5
    ISSN 1095-7103 ; 0021-9797
    ISSN (online) 1095-7103
    ISSN 0021-9797
    DOI 10.1016/j.jcis.2022.11.049
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  8. Article ; Online: Correlated P300b and phasic pupil-dilation responses to motivationally significant stimuli.

    Menicucci, Danilo / Animali, Silvia / Malloggi, Eleonora / Gemignani, Angelo / Bonanni, Enrica / Fornai, Francesco / Giorgi, Filippo Sean / Binda, Paola

    Psychophysiology

    2024  , Page(s) e14550

    Abstract: ... pupil dilations and P300b are tightly and positively correlated (across participants: r = .69 p = .002 ...

    Abstract Motivationally significant events like oddball stimuli elicit both a characteristic event-related potential (ERPs) known as P300 and a set of autonomic responses including a phasic pupil dilation. Although co-occurring, P300 and pupil-dilation responses to oddball events have been repeatedly found to be uncorrelated, suggesting separate origins. We re-examined their relationship in the context of a three-stimulus version of the auditory oddball task, independently manipulating the frequency (rare vs. repeated) and motivational significance (relevance for the participant's task) of the stimuli. We used independent component analysis to derive a P300b component from EEG traces and linear modeling to separate a stimulus-related pupil-dilation response from a potentially confounding action-related response. These steps revealed that, once the complexity of ERP and pupil-dilation responses to oddball targets is accounted for, the amplitude of phasic pupil dilations and P300b are tightly and positively correlated (across participants: r = .69 p = .002), supporting their coordinated generation.
    Language English
    Publishing date 2024-03-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 209486-1
    ISSN 1469-8986 ; 1540-5958 ; 0048-5772
    ISSN (online) 1469-8986 ; 1540-5958
    ISSN 0048-5772
    DOI 10.1111/psyp.14550
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Dispersion without Many-Body Density Distortion: Assessment on Atoms and Small Molecules.

    Kooi, Derk P / Weckman, Timo / Gori-Giorgi, Paola

    Journal of chemical theory and computation

    2021  Volume 17, Issue 4, Page(s) 2283–2293

    Abstract: The "fixed diagonal matrices" (FDM) dispersion formalism [Kooi, D. P.; et al. ...

    Abstract The "fixed diagonal matrices" (FDM) dispersion formalism [Kooi, D. P.; et al.
    Language English
    Publishing date 2021-03-10
    Publishing country United States
    Document type Journal Article
    ISSN 1549-9626
    ISSN (online) 1549-9626
    DOI 10.1021/acs.jctc.1c00102
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  10. Article ; Online: An α-Gal antigenic surrogate as a biomarker of treatment evaluation in Trypanosoma cruzi-infected children. A retrospective cohort study.

    Abal, Manuel / Balouz, Virginia / Lopez, Rosana / Giorgi, M Eugenia / Marino, Carla / Cruz, Cintia V / Altcheh, Jaime / Buscaglia, Carlos A

    PLoS neglected tropical diseases

    2024  Volume 18, Issue 1, Page(s) e0011910

    Abstract: ... d-Galp(1→3)-β-d-Galp(1→4)-d-GlcNAc)-rich fraction obtained from T. cruzi trypomastigotes surface ... antigenic surrogate (α-d-Galp(1→3)-β-d-Galp(1→4)-β-d-Glcp). Serological responses to this reagent, termed ... to 36 months] vs 60 months [IC 95% 15 to 83 months]; p = 0.0016) and higher rate of patient negative ...

    Abstract Background: Proper evaluation of therapeutic responses in Chagas disease is hampered by the prolonged persistence of antibodies to Trypanosoma cruzi measured by conventional serological tests and by the lack of sensitivity of parasitological tests. Previous studies indicated that tGPI-mucins, an α-Gal (α-d-Galp(1→3)-β-d-Galp(1→4)-d-GlcNAc)-rich fraction obtained from T. cruzi trypomastigotes surface coat, elicit a strong and protective antibody response in infected individuals, which disappears soon after successful treatment. The cost and technical difficulties associated with tGPI-mucins preparation, however, preclude its routine implementation in clinical settings.
    Methods/principle findings: We herein developed a neoglycoprotein consisting of a BSA scaffold decorated with several units of a synthetic α-Gal antigenic surrogate (α-d-Galp(1→3)-β-d-Galp(1→4)-β-d-Glcp). Serological responses to this reagent, termed NGP-Tri, were monitored by means of an in-house enzyme-linked immunosorbent assay (α-Gal-ELISA) in a cohort of 82 T. cruzi-infected and Benznidazole- or Nifurtimox-treated children (3 days to 16 years-old). This cohort was split into 3 groups based on the age of patients at the time of treatment initiation: Group 1 comprised 24 babies (3 days to 5 months-old; median = 26 days-old), Group 2 comprised 31 children (7 months to 3 years-old; median = 1.0-year-old) and Group 3 comprised 26 patients (3 to 16 years-old; median = 8.4 years-old). A second, control cohort (Group 4) included 39 non-infected infants (3 days to 5 months-old; median = 31 days-old) born to T. cruzi-infected mothers. Despite its suboptimal seroprevalence (58.4%), α-Gal-ELISA yielded shorter median time values of negativization (23 months [IC 95% 7 to 36 months] vs 60 months [IC 95% 15 to 83 months]; p = 0.0016) and higher rate of patient negative seroconversion (89.2% vs 43.2%, p < 0.005) as compared to conventional serological methods. The same effect was verified for every Group, when analyzed separately. Most remarkably, 14 out of 24 (58.3%) patients from Group 3 achieved negative seroconversion for α-Gal-ELISA while none of them were able to negativize for conventional serology. Detailed analysis of patients showing unconventional serological responses suggested that, in addition to providing a novel tool to shorten follow-up periods after chemotherapy, the α-Gal-ELISA may assist in other diagnostic needs in pediatric Chagas disease.
    Conclusions/significance: The tools evaluated here provide the cornerstone for the development of an efficacious, reliable, and straightforward post-therapeutic marker for pediatric Chagas disease.
    MeSH term(s) Infant ; Female ; Humans ; Child ; Infant, Newborn ; Child, Preschool ; Adolescent ; Trypanosoma cruzi ; Retrospective Studies ; Seroepidemiologic Studies ; Chagas Disease/diagnosis ; Chagas Disease/drug therapy ; Enzyme-Linked Immunosorbent Assay ; Mucins ; Biomarkers ; Antibodies, Protozoan
    Chemical Substances Mucins ; Biomarkers ; Antibodies, Protozoan
    Language English
    Publishing date 2024-01-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2429704-5
    ISSN 1935-2735 ; 1935-2735
    ISSN (online) 1935-2735
    ISSN 1935-2735
    DOI 10.1371/journal.pntd.0011910
    Database MEDical Literature Analysis and Retrieval System OnLINE

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