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  1. Article: Hemorrhagic Fever with Renal Syndrome: Literature Review, Epidemiology, Clinical Picture and Pathogenesis.

    Tariq, Misbah / Kim, Dong-Min

    Infection & chemotherapy

    2022  Volume 54, Issue 1, Page(s) 1–19

    Abstract: Hantaviruses can cause two types of infections in humans: hemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome. The old world hantaviruses, primarily Hantaan virus (HTNV), responsible for causing HFRS occurs endemically in Asia ... ...

    Abstract Hantaviruses can cause two types of infections in humans: hemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome. The old world hantaviruses, primarily Hantaan virus (HTNV), responsible for causing HFRS occurs endemically in Asia and Europe.
    Language English
    Publishing date 2022-04-05
    Publishing country Korea (South)
    Document type Journal Article ; Review
    ZDB-ID 2573798-3
    ISSN 2093-2340
    ISSN 2093-2340
    DOI 10.3947/ic.2021.0148
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Comparison Of Exergaming And Vestibular Training On Gaze Stability, Balance And Gait Performance Of Older Adults: A Single Blind Randomized Control Trial.

    Bukhari, Syeda Amna / Ghous, Misbah / Butt, Poshmal / Kiyani, Sania Khawar / Tariq, Aroosa

    JPMA. The Journal of the Pakistan Medical Association

    2023  Volume 73, Issue 8, Page(s) 1761

    MeSH term(s) Humans ; Aged ; Exergaming ; Single-Blind Method ; Ear Diseases
    Language English
    Publishing date 2023-09-12
    Publishing country Pakistan
    Document type Randomized Controlled Trial ; Journal Article
    ZDB-ID 603873-6
    ISSN 0030-9982
    ISSN 0030-9982
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Exploring the Sensing Potential of g-C

    Asif, Misbah / Kosar, Naveen / Sajid, Hasnain / Qureshi, Sana / Gilani, Mazhar Amjad / Ayub, Khurshid / Arshad, Muhammad / Imran, Muhammad / Hamid, Malai Haniti S A / Bayach, Imene / Sheikh, Nadeem S / Mahmood, Tariq

    ACS omega

    2024  Volume 9, Issue 3, Page(s) 3541–3553

    Abstract: ... Ab ... ...

    Abstract Ab initio
    Language English
    Publishing date 2024-01-12
    Publishing country United States
    Document type Journal Article
    ISSN 2470-1343
    ISSN (online) 2470-1343
    DOI 10.1021/acsomega.3c07350
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Synthesis, In Vitro Biological Evaluation and Molecular Modeling of Benzimidazole-Based Pyrrole/Piperidine Hybrids Derivatives as Potential Anti-Alzheimer Agents.

    Tariq, Sundas / Rahim, Fazal / Ullah, Hayat / Sarfraz, Maliha / Hussain, Rafaqat / Khan, Shoaib / Khan, Misbah Ullah / Rehman, Wajid / Hussain, Amjad / Bhat, Mashooq Ahmad / Farooqi, Muhammad Kamran / Shah, Syed Adnan Ali / Iqbal, Naveed

    Pharmaceuticals (Basel, Switzerland)

    2024  Volume 17, Issue 4

    Abstract: Benzimidazole-based pyrrole/piperidine analogs ( ...

    Abstract Benzimidazole-based pyrrole/piperidine analogs (
    Language English
    Publishing date 2024-03-24
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2193542-7
    ISSN 1424-8247
    ISSN 1424-8247
    DOI 10.3390/ph17040410
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Microwave- and ultrasound-assisted extraction of capsaicin from Capsicum annuum using deep eutectic solvents

    Hussain, Misbah / Qamar, Muhammad Tariq / Ahmed, Dildar

    International journal of vegetable science

    2022  Volume 28, Issue 1/6, Page(s) 312

    Language English
    Document type Article
    ZDB-ID 2390923-7
    ISSN 1931-5260
    Database Current Contents Nutrition, Environment, Agriculture

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  6. Article: Comparison of exergaming and vestibular training on gaze stability, balance, and gait performance of older adults: A single blind randomized control trial.

    Bukhari, Syeda Amna / Ghous, Misbah / Butt, Poshmal / Kiyani, Sania Khawar / Tariq, Aroosa

    JPMA. The Journal of the Pakistan Medical Association

    2023  Volume 72, Issue 10, Page(s) 1909–1912

    Abstract: Objectives: To compare the effects of exergaming and vestibular training on gaze stability, balance and gait performance of older adults.: Methods: The single-blind randomised controlled trial was conducted from August to October 2020 at the Doctor ... ...

    Abstract Objectives: To compare the effects of exergaming and vestibular training on gaze stability, balance and gait performance of older adults.
    Methods: The single-blind randomised controlled trial was conducted from August to October 2020 at the Doctor Raza Clinic, Swabi, Pakistan, and comprised individuals of both genders aged 60-75 years. The subjects were randomised into two groups using the sealed envelope method. Group 1 received exergaming, while group 2 received vestibular training 3 days a week for 6 weeks. The outcomes measures were dynamic gait index, time up and go test and non-instrumented dynamic visual acuity test. Data was analysed using SPSS 21.
    Results: Of the 24 subjects, 12(50%) were in each of the two groups. Overall, there were 16(66%) males and 8(33%) females with a mean age of 66.3±4.36 years. Intra-group improvement was significant compared to the baseline (p<0.05) in both the differences, but inter-group differences across all parameters were non-significant (p>0.05).
    Conclusions: Both exergaming and vestibular training has similar effects on gaze stability, balance, and gait performance among the older adults. Clinical Trials.gov Identifier: NCT04414462.
    MeSH term(s) Humans ; Male ; Female ; Aged ; Middle Aged ; Single-Blind Method ; Exergaming ; Exercise Therapy/methods ; Postural Balance ; Time and Motion Studies ; Gait
    Language English
    Publishing date 2023-01-20
    Publishing country Pakistan
    Document type Randomized Controlled Trial ; Journal Article
    ZDB-ID 603873-6
    ISSN 0030-9982
    ISSN 0030-9982
    DOI 10.47391/JPMA.3566
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Microwave- and ultrasound-assisted extraction of capsaicin from Capsicum annuum using deep eutectic solvents

    Hussain, Misbah / Qamar, Muhammad Tariq / Ahmed, Dildar

    International journal of vegetable science. 2022 July 04, v. 28, no. 4

    2022  

    Abstract: Methods exist to extract capsaicin from chili (Capsicum annuum L.), but they have poor yield and are hazardous to the environment. The objective of the study was to develop a process for extraction of capsaicin from chili that is more efficient and bio- ... ...

    Abstract Methods exist to extract capsaicin from chili (Capsicum annuum L.), but they have poor yield and are hazardous to the environment. The objective of the study was to develop a process for extraction of capsaicin from chili that is more efficient and bio-rationale. Two deep eutectic solvents (DES), choline chloride-urea (CCU) and choline chloride-glycerol (CCG), were used for extraction with MAE (microwave-assisted extraction) and UAE (ultrasound-assisted extraction). In MAE, the highest yield in both solvents was at 600 W and solvent-solid ratio 30 mL∙g⁻¹ for CCU 18.88 mg∙g⁻¹ and for CCG 14.49 mg∙g⁻¹. In UAE, the highest yield in both solvents was at 50°C and solvent-solid ratio 100 mL∙g⁻¹ (2.77 for CCU and 2.59 mg∙g⁻¹ for CCG). The CCU (1:2) was an efficient solvent for extraction of capsaicin from chili and MAE was more efficient than UAE (ultrasound-assisted extraction). The results provide a new method to obtain capsaicin efficiently from C. annuum.
    Keywords Capsicum annuum ; capsaicin ; choline ; microwave treatment ; solvents ; ultrasonic treatment ; vegetables
    Language English
    Dates of publication 2022-0704
    Size p. 312-319.
    Publishing place Taylor & Francis
    Document type Article
    ZDB-ID 2390923-7
    ISSN 1540-7357 ; 1548-1697 ; 1931-5279 ; 1931-5260 ; 1049-6467 ; 1548-1689
    ISSN (online) 1540-7357 ; 1548-1697 ; 1931-5279
    ISSN 1931-5260 ; 1049-6467 ; 1548-1689
    DOI 10.1080/19315260.2021.1960459
    Database NAL-Catalogue (AGRICOLA)

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  8. Article ; Online: Therapeutic potential of oxo-triarylmethyl (oxTAM) as a targeted drug delivery system for nitrosourea and fluorouracil anticancer drugs; A first principles insight.

    Asif, Misbah / Sajid, Hasnain / Ayub, Khurshid / Gilani, Mazhar Amjad / Anwar, Naeem / Mahmood, Tariq

    Journal of molecular graphics & modelling

    2023  Volume 122, Page(s) 108469

    Abstract: In this study, oxygenated triarylmethyl (oxTAM) is investigated by DFT calculations as a drug carrier framework for Nitrosourea (NU) and Fluorouracil (FU) drugs. Based on the adsorption analysis i.e., energies and distances between interacting atoms, it ... ...

    Abstract In this study, oxygenated triarylmethyl (oxTAM) is investigated by DFT calculations as a drug carrier framework for Nitrosourea (NU) and Fluorouracil (FU) drugs. Based on the adsorption analysis i.e., energies and distances between interacting atoms, it is found that oxTAM exhibits excellent carrier abilities for the delivery of FU (-1.53 eV & 2.00 Å) and NU (-1.33 eV & 2.12 Å) drugs. NCI and QTAIM results indicate the presence of hydrogen bonding in drug-carrier complexes. The values of dipole moment and global chemical descriptors show the significant reactivity of oxTAM for NU and FU drugs. Based on electronic property analysis, FU@oxTAM has a higher adsorption trend for complexation with oxTAM as compared to NU@oxTAM. Moreover, FU can easily release from the carrier due to the decreasing adsorption stability after protonation under an acidic environment as well as a short recovery time observed for the oxTAM carrier surface. Keeping in view all the above parameters, we inferred that oxTAM can serve as a potential drug delivery system for anticancer drugs including, Nitrosourea and Fluorouracil drugs.
    MeSH term(s) Antineoplastic Agents/pharmacology ; Antineoplastic Agents/chemistry ; Fluorouracil/pharmacology ; Fluorouracil/chemistry ; Drug Delivery Systems ; Drug Carriers ; Nitrosourea Compounds
    Chemical Substances Antineoplastic Agents ; Fluorouracil (U3P01618RT) ; Drug Carriers ; Nitrosourea Compounds
    Language English
    Publishing date 2023-04-10
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1396450-1
    ISSN 1873-4243 ; 1093-3263
    ISSN (online) 1873-4243
    ISSN 1093-3263
    DOI 10.1016/j.jmgm.2023.108469
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Safety and efficacy of minimally invasive percutaneous nephrolithotomy for infantile nephrolithiasis. Single centre experience from Pakistan.

    Ahmad, Tariq / Minallah, Nasrum / Khaliq, Nida / Rashid, Hania / Syed, Misbah / Almuradi, Moath Ahmad Abdullah

    Frontiers in pediatrics

    2023  Volume 10, Page(s) 1035964

    Abstract: Objective: To assess the efficacy and safety of mini-percutaneous nephrolithotomy (PCNL) for small renal stones 1-2 cm in size in infants less than one year.: Material and methods: This descriptive case series was conducted in the department of ... ...

    Abstract Objective: To assess the efficacy and safety of mini-percutaneous nephrolithotomy (PCNL) for small renal stones 1-2 cm in size in infants less than one year.
    Material and methods: This descriptive case series was conducted in the department of pediatric urology Institute of Kidney Diseases Peshawar, Pakistan, from March 2019 to March 2022. All the patients underwent mini-PCNL in prone position under GA with 14 Fr access sheath and 10 Fr nephroscope. Stone clearance was assessed by non-contrast CT KUB at 30th postoperative day. Patients with no residual fragments on the non-contrast CT KUB were defined as stone-free. Patients with residual fragments of any size were defined as procedure failure. Safety was determined in terms of intra and postoperative complications.
    Results: A total of 51 infants were included in the study. The mean age of patients was 9.6 + 1.8 (5-12 month). The mean stone size was 15.8 + 2.7 (10-21) mm in length and 12.3 + 2.2 (8-17) mm in width. PCNL mean operative time was 51.6 ± 7.1 (40-70) minutes. Complete stone clearance at one month was observed in 46 (90.2%) patients. Residual fragments were seen in 5(9.8%) patients with a mean size of 1.6 + 0.4 (0.9-2.0) mm. None of the patients required any additional procedure for clearance of stones. In 7 (13.7%) patients, some post-operative complications were observe, all were grade I complications, including fever in 5(9.8%) and transient hematuria in 2(3.9%) patients.
    Conclusion: Mini-PCNL is a safe and effective treatment for renal stones in infants measuring 1-2 cm with high SFR and an acceptable complication rate.
    Language English
    Publishing date 2023-01-16
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2711999-3
    ISSN 2296-2360
    ISSN 2296-2360
    DOI 10.3389/fped.2022.1035964
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Agonistic antibacterial potential of Loigolactobacillus coryniformis BCH-4 metabolites against selected human pathogenic bacteria: An in vitro and in silico approach.

    Tariq, Anam / Salman, Mahwish / Mustafa, Ghulam / Tawab, Abdul / Naheed, Shazia / Naz, Hafsa / Shahid, Misbah / Ali, Hazrat

    PloS one

    2023  Volume 18, Issue 8, Page(s) e0289723

    Abstract: Lactic acid bacteria are known to produce numerous antibacterial metabolites that are active against various pathogenic microbes. In this study, bioactive metabolites from the cell free supernatant of Loigolactobacillus coryniformis BCH-4 were obtained ... ...

    Abstract Lactic acid bacteria are known to produce numerous antibacterial metabolites that are active against various pathogenic microbes. In this study, bioactive metabolites from the cell free supernatant of Loigolactobacillus coryniformis BCH-4 were obtained by liquid-liquid extraction, using ethyl acetate, followed by fractionation, using silica gel column chromatography. The collected F23 fraction effectively inhibited the growth of pathogenic bacteria (Escherichia coli, Bacillus cereus, and Staphylococcus aureus) by observing the minimum inhibitory concentration (MIC) and minimum bactericidal concentrations (MBC). The evaluated values of MIC were 15.6 ± 0.34, 3.9 ± 0.59, and 31.2 ± 0.67 μg/mL and MBC were 15.6 ± 0.98, 7.8 ± 0.45, and 62.5 ± 0.23 μg/mL respectively, against the above-mentioned pathogenic bacteria. The concentration of F23 fraction was varying from 1000 to 1.9 μg/mL. Furthermore, the fraction also exhibited sustainable biofilm inhibition. Using the Electrospray Ionization Mass Spectrometry (ESI-MS/MS), the metabolites present in the bioactive fraction (F23), were identified as phthalic acid, myristic acid, mangiferin, 16-hydroxylpalmatic acid, apigenin, and oleandomycin. By using in silico approach, docking analysis showed good interaction of identified metabolites and receptor proteins of pathogenic bacteria. The present study suggested Loigolactobacillus coryniformis BCH-4, as a promising source of natural bioactive metabolites which may receive great benefit as potential sources of drugs in the pharmacological sector.
    MeSH term(s) Humans ; Tandem Mass Spectrometry ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/chemistry ; Staphylococcus aureus ; Bacillus cereus ; Microbial Sensitivity Tests
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2023-08-10
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0289723
    Database MEDical Literature Analysis and Retrieval System OnLINE

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