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  1. Article ; Online: Short-term results of thoracoscopic lobectomy and segmentectomy for lung cancer in koo foundation sun yat-sen cancer center.

    Wang, Bing-Yen / Liu, Chia-Chuan / Shih, Chih-Shiun

    Journal of thoracic disease

    2011  Volume 2, Issue 2, Page(s) 64–70

    Abstract: ... vertical minithoracotomy in Koo Foundation Sun Yat-Sen Cancer Center.: Methods: We performed ... Yat-Sen Cancer center between Jan 2000 and Jun 2009. The operative details, postoperative complication ...

    Abstract Background: Thoracoscopic lobectomy and segmentectomy have been demonstrated to be safe and technically feasible for curative resection of lung cancer. This minimally invasive surgery is increasingly popular and adopted by the world all over. We report our short-term results of thoracoscopic lobectomy/segmentectomy operations comparing with previous surgical approach for lung cancer resection by muscle-sparing vertical minithoracotomy in Koo Foundation Sun Yat-Sen Cancer Center.
    Methods: We performed a retrospective review of 317 consecutive patients who underwent lobectomy or segmentectomy either by thoracoscopic surgery (n=121) or muscle-sparing vertical mini-thoracotomy (n=195) for lung cancer in Koo Foundation Sun Yat-Sen Cancer center between Jan 2000 and Jun 2009. The operative details, postoperative complication, and length of stay were statistically analyzed.
    Results: Thoracoscopic lobectomy and segmentectomy were performed successfully in 121 patients. One patient was converted to open thoracotomy during operation due to uncontrolled bleeding. There is no significant difference in age factors (p=0.763), forced expiratory volume in one second (p=0.480) or comorbidities (p=0.549) between these two groups. Thoracoscopic group had a significantly predominant percentage in women, diabetes mellitus, less smoking index and chronic obstructive pulmonary disease incidence. Patients undergoing a thoracoscopic surgery had a shorter length of stay (6.8±3.4 vs. 10.2±9.1 days, p<0.001), longer operative time (3.6±1.0 vs. 3.2±1.2 hours, p=0.004), and less blood loss (102.7±95.7 vs. 140.1±171.2 ml, p<0.029). There was no significant difference in postoperative complication rate between the two groups (18.2% vs. 23.6%, p=0.255). No surgical mortality was found in the thoracoscopic group.
    Conclusions: Our findings suggested thoracoscopic surgery for lung cancer would be as safe as muscle-sparing vertical mini-thoracotomy in lobectomy and segmentectomy.
    Language English
    Publishing date 2011-11-04
    Publishing country China
    Document type Journal Article
    ZDB-ID 2573571-8
    ISSN 2077-6624 ; 2077-6624
    ISSN (online) 2077-6624
    ISSN 2077-6624
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Book ; Online ; E-Book: Optimizing aesthetic toxin results

    Chao, Yates Yen-Yu

    (Series in Cosmetic and Laser Therapy)

    2021  

    Abstract: Botulinum toxin injections are the most used and best-known aesthetic treatment internationally, but there remain a number of problematic topics and suboptimal results. Here an internationally known expert and his contributors explain the scientific ... ...

    Author's details edited by Yates Yen-Yu Chao
    Series title Series in Cosmetic and Laser Therapy
    Abstract "Botulinum toxin injections are the most used and best-known aesthetic treatment internationally, but there remain a number of problematic topics and suboptimal results. Here an internationally known expert and his contributors explain the scientific background and aesthetic principles that can help clinicians achieve better results in problem cases"--
    Keywords Botulinum toxin ; Botulinum toxin/Therapeutic use.
    Subject code 615.778
    Language English
    Size 1 online resource (165 pages)
    Edition First edition.
    Publisher CRC Press
    Publishing place Boca Raton, Florida
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 1-00-300813-5 ; 1-000-53358-1 ; 1-000-53355-7 ; 1-003-00813-5 ; 0-367-44185-3 ; 978-1-00-300813-2 ; 978-1-000-53358-3 ; 978-1-000-53355-2 ; 978-1-003-00813-2 ; 978-0-367-44185-2
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Article ; Online: Corporate Governance Codes and Intellectual Capital

    Chang Yen Wen / David Ng Ching Yat / Low Suet Cheng / Tee Peck Ling

    SHS Web of Conferences, Vol 124, p

    Evaluating the Performance Impacts among Government-Linked Companies in Malaysia and Singapore – A Panel Data Analysis

    2021  Volume 08004

    Abstract: The objective of this study was to examine and compare the effects of corporate governance (CG) and intellectual capital (IC) between Malaysia Government-Linked Companies’ (M-GLCs) and Singapore Government-Linked Companies’ (S-GLCs) firm performance (FP). ...

    Abstract The objective of this study was to examine and compare the effects of corporate governance (CG) and intellectual capital (IC) between Malaysia Government-Linked Companies’ (M-GLCs) and Singapore Government-Linked Companies’ (S-GLCs) firm performance (FP). Panel data analysis was employed to analyse the impact of CG’s variables and IC’s variables on FP. FP was measured by Return on Total Assets (ROA), Tobin’s Q and Earnings Per Share (EPS). Data was gathered from the website of Bursa Malaysia and the Stock Exchange of Singapore from 2005 to 2018. The sample size of this research was 60 GLCs which comprised of 34 M-GLCs and 26 S-GLCs. There were a total 840 firm year observations. Results indicated that CGs of S-GLCs have greater impact on FP when compared to M-GLCs while the findings of the IC of M-GLCs have greater impact on FP compared to S-GLCs. This research was helpful in offering further insights of CG practices and IC efficiency to the Government, Board of Directors, policy makers, shareholders and stakeholders.
    Keywords Social Sciences ; H
    Subject code 306
    Language English
    Publishing date 2021-01-01T00:00:00Z
    Publisher EDP Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Book ; Online ; E-Book: Adapting dermal fillers in clinical practice

    Cotofana, Sebastian / Chao, Yates Yen-Yu

    (Series in Cosmetic and Laser Therapy)

    2022  

    Abstract: This innovative text explains how standard dermal filler injections and techniques need to be adapted, refined, or developed for different indications in different types of patient. It is organized by the scenarios likely to arise with different ... ...

    Author's details edited by Yates Yen-Yu Chao and Sebastian Cotofana
    Series title Series in Cosmetic and Laser Therapy
    Abstract "This innovative text explains how standard dermal filler injections and techniques need to be adapted, refined, or developed for different indications in different types of patient. It is organized by the scenarios likely to arise with different patients as a quick way to find the answer to a clinical problem"--
    Keywords Surgery, Plastic ; Injections, Hypodermic
    Subject code 617.52059
    Language English
    Size 1 online resource (283 pages)
    Publisher CRC Press
    Publishing place Boca Raton, Florida
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 0-429-52266-5 ; 0-429-26052-0 ; 0-367-20255-7 ; 978-0-429-52266-6 ; 978-0-429-26052-0 ; 978-0-367-20255-2
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  5. Article ; Online: Analysis of Urban Drivable and Walkable Street Networks of the ASEAN Smart Cities Network

    Pengjun Zhao / Yat Yen / Earl Bailey / Muhammad Tayyab Sohail

    ISPRS International Journal of Geo-Information, Vol 8, Iss 10, p

    2019  Volume 459

    Abstract: Making transport systems sustainable is a topic that has attracted the attention of many researchers and urban planners. The Association of Southeast Asian Nations (ASEAN) Smart Cities Network (ASCN) was initiated to develop a sustainable transport ... ...

    Abstract Making transport systems sustainable is a topic that has attracted the attention of many researchers and urban planners. The Association of Southeast Asian Nations (ASEAN) Smart Cities Network (ASCN) was initiated to develop a sustainable transport system in the ASEAN countries. A comprehensive understanding of street networks (SNs) can contribute significantly to the achievement of this initiative. Therefore, this paper measured and compared characteristics of drivable street networks (DSNs) and walkable street networks (WSNs) of the 26 ASCN pilot cities by applying multiple network metrics. The OSMnx tool was used to download and analyse WSNs and DSNs from the OpenStreetMap. The findings present the topological and geometric characteristics of WSNs and DSNs that are diverse and characterized by different factors. The cities with orthogonal street grids, high street density, intersection density, and fewer cul-de-sacs have good accessibility to reach destinations. In contrast, some other cities have more curvilinear and circuitous SNs with many missing links to other streets, which in turn are prone to traffic disruption. The study highlights the important features of SNs that have significant implications for future designs of SNs in the ASCN whose goal is to make cities smart and liveable for ASEAN members.
    Keywords osmnx ; openstreetmap ; street network analysis ; urban morphology ; smart city ; Geography (General) ; G1-922
    Language English
    Publishing date 2019-10-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Epicardium-derived cells organize through tight junctions to replenish cardiac muscle in salamanders.

    Eroglu, Elif / Yen, Christopher Y T / Tsoi, Yat-Long / Witman, Nevin / Elewa, Ahmed / Joven Araus, Alberto / Wang, Heng / Szattler, Tamara / Umeano, Chimezie H / Sohlmér, Jesper / Goedel, Alexander / Simon, András / Chien, Kenneth R

    Nature cell biology

    2022  Volume 24, Issue 5, Page(s) 645–658

    Abstract: The contribution of the epicardium, the outermost layer of the heart, to cardiac regeneration has remained controversial due to a lack of suitable analytical tools. By combining genetic marker-independent lineage-tracing strategies with transcriptional ... ...

    Abstract The contribution of the epicardium, the outermost layer of the heart, to cardiac regeneration has remained controversial due to a lack of suitable analytical tools. By combining genetic marker-independent lineage-tracing strategies with transcriptional profiling and loss-of-function methods, we report here that the epicardium of the highly regenerative salamander species Pleurodeles waltl has an intrinsic capacity to differentiate into cardiomyocytes. Following cryoinjury, CLDN6
    MeSH term(s) Animals ; Mammals ; Myocardium ; Myocytes, Cardiac/pathology ; Pericardium/pathology ; Pericardium/physiology ; Tight Junctions ; Urodela/genetics
    Language English
    Publishing date 2022-05-12
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural
    ZDB-ID 1474722-4
    ISSN 1476-4679 ; 1465-7392
    ISSN (online) 1476-4679
    ISSN 1465-7392
    DOI 10.1038/s41556-022-00902-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: An Assessment of the Knowledge and Demand of Young Residents regarding the Ecological Services of Urban Green Spaces in Phnom Penh, Cambodia

    Yat Yen / Zhanqi Wang / Yumin Shi / Bunly Soeung

    Sustainability, Vol 8, Iss 6, p

    2016  Volume 523

    Abstract: The fast and steady economic growth and social changes in recent years in Cambodia have brought rapid expansion and restructuring to its cities. These phenomena have brought numerous challenges including threats to urban green spaces (UGS’s). This study ... ...

    Abstract The fast and steady economic growth and social changes in recent years in Cambodia have brought rapid expansion and restructuring to its cities. These phenomena have brought numerous challenges including threats to urban green spaces (UGS’s). This study addresses problems of UGS’s by investigating the knowledge and perceptions of young residents of Phnom Penh (YRPPs) toward UGS’s in relation to the following: (1) basic knowledge of YRPPs on ecological services (KES) of UGS’s; (2) perceptions of YRPPs on the current state of UGS’s (PUGS’s) in Phnom Penh; (3) demand of YRPPs for UGS’s in the city (DUGS); and (4) associations between KES, PUGS’s, social profiles (SoPs), and DUGS. A questionnaire was designed to solicit knowledge from 554 respondents randomly selected from the study area. The findings revealed that 83.1% of total respondents strongly recognized ecological services of UGS’s. Four subgroups of ecological services, namely microclimate (89.7%), environmental quality and functions (83.8%), recreational and public health services (88.5%), and economic benefits (70.4%) were all rated highly. Because the current state of UGS’s was very poor (68.4%), demand for UGS’s was high (94.43%). Public toilets (84.7%) and rubbish bins (75.6%) were both rated the poorest. The PUGS’s were significantly associated with KES (r = 0.307, F (3, 543) = 18.83, p < 0.001). This study offers a deep understanding about knowledge and demand of YRPPs for UGS’s.
    Keywords young resident ; basic knowledge ; green space ; ecological service ; Phnom Penh ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
    Subject code 360
    Language English
    Publishing date 2016-05-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Ultra-fast multi-parametric 4D-MRI image reconstruction for real-time applications using a downsampling-invariant deformable registration (D2R) model.

    Xiao, Haonan / Han, Xinyang / Zhi, Shaohua / Wong, Yat-Lam / Liu, Chenyang / Li, Wen / Liu, Weiwei / Wang, Weihu / Zhang, Yibao / Wu, Hao / Lee, Ho-Fun Victor / Cheung, Lai-Yin Andy / Chang, Hing-Chiu / Liao, Yen-Peng / Deng, Jie / Li, Tian / Cai, Jing

    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

    2023  Volume 189, Page(s) 109948

    Abstract: Background and purpose: Motion estimation from severely downsampled 4D-MRI is essential for real-time imaging and tumor tracking. This simulation study developed a novel deep learning model for simultaneous MR image reconstruction and motion estimation, ...

    Abstract Background and purpose: Motion estimation from severely downsampled 4D-MRI is essential for real-time imaging and tumor tracking. This simulation study developed a novel deep learning model for simultaneous MR image reconstruction and motion estimation, named the Downsampling-Invariant Deformable Registration (D2R) model.
    Materials and methods: Forty-three patients undergoing radiotherapy for liver tumors were recruited for model training and internal validation. Five prospective patients from another center were recruited for external validation. Patients received 4D-MRI scans and 3D MRI scans. The 4D-MRI was retrospectively down-sampled to simulate real-time acquisition. Motion estimation was performed using the proposed D2R model. The accuracy and robustness of the proposed D2R model and baseline methods, including Demons, Elastix, the parametric total variation (pTV) algorithm, and VoxelMorph, were compared. High-quality (HQ) 4D-MR images were also constructed using the D2R model for real-time imaging feasibility verification. The image quality and motion accuracy of the constructed HQ 4D-MRI were evaluated.
    Results: The D2R model showed significantly superior and robust registration performance than all the baseline methods at downsampling factors up to 500. HQ T1-weighted and T2-weighted 4D-MR images were also successfully constructed with significantly improved image quality, sub-voxel level motion error, and real-time efficiency. External validation demonstrated the robustness and generalizability of the technique.
    Conclusion: In this study, we developed a novel D2R model for deformation estimation of downsampled 4D-MR images. HQ 4D-MR images were successfully constructed using the D2R model. This model may expand the clinical implementation of 4D-MRI for real-time motion management during liver cancer treatment.
    MeSH term(s) Humans ; Prospective Studies ; Retrospective Studies ; Image Processing, Computer-Assisted/methods ; Magnetic Resonance Imaging/methods ; Motion ; Liver Neoplasms/diagnostic imaging ; Liver Neoplasms/radiotherapy
    Language English
    Publishing date 2023-10-11
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 605646-5
    ISSN 1879-0887 ; 0167-8140
    ISSN (online) 1879-0887
    ISSN 0167-8140
    DOI 10.1016/j.radonc.2023.109948
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: An Assessment of the Knowledge and Demand of Young Residents regarding the Ecological Services of Urban Green Spaces in Phnom Penh, Cambodia

    Yen, Yat / Wang, Zhanqi / Shi, Yumin / Soeung, Bunly

    Sustainability. 2016 May 31, v. 8, no. 6

    2016  

    Abstract: The fast and steady economic growth and social changes in recent years in Cambodia have brought rapid expansion and restructuring to its cities. These phenomena have brought numerous challenges including threats to urban green spaces (UGS’s). This study ... ...

    Abstract The fast and steady economic growth and social changes in recent years in Cambodia have brought rapid expansion and restructuring to its cities. These phenomena have brought numerous challenges including threats to urban green spaces (UGS’s). This study addresses problems of UGS’s by investigating the knowledge and perceptions of young residents of Phnom Penh (YRPPs) toward UGS’s in relation to the following: (1) basic knowledge of YRPPs on ecological services (KES) of UGS’s; (2) perceptions of YRPPs on the current state of UGS’s (PUGS’s) in Phnom Penh; (3) demand of YRPPs for UGS’s in the city (DUGS); and (4) associations between KES, PUGS’s, social profiles (SoPs), and DUGS. A questionnaire was designed to solicit knowledge from 554 respondents randomly selected from the study area. The findings revealed that 83.1% of total respondents strongly recognized ecological services of UGS’s. Four subgroups of ecological services, namely microclimate (89.7%), environmental quality and functions (83.8%), recreational and public health services (88.5%), and economic benefits (70.4%) were all rated highly. Because the current state of UGS’s was very poor (68.4%), demand for UGS’s was high (94.43%). Public toilets (84.7%) and rubbish bins (75.6%) were both rated the poorest. The PUGS’s were significantly associated with KES (r = 0.307, F (3, 543) = 18.83, p < 0.001). This study offers a deep understanding about knowledge and demand of YRPPs for UGS’s.
    Keywords cities ; economic development ; ecosystem services ; environmental quality ; financial economics ; green infrastructure ; health services ; microclimate ; public health ; questionnaires ; social change ; Cambodia
    Language English
    Dates of publication 2016-0531
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article
    ZDB-ID 2518383-7
    ISSN 2071-1050
    ISSN 2071-1050
    DOI 10.3390/su8060523
    Database NAL-Catalogue (AGRICOLA)

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  10. Article: Analysis of Urban Drivable and Walkable Street Networks of the ASEAN Smart Cities Network

    Zhao, Pengjun / Bailey, Earl / Sohail, Muhammad Tayyab / Yen, Yat

    ISPRS international journal of geo-information. 2019 Oct. 16, v. 8, no. 10

    2019  

    Abstract: Making transport systems sustainable is a topic that has attracted the attention of many researchers and urban planners. The Association of Southeast Asian Nations (ASEAN) Smart Cities Network (ASCN) was initiated to develop a sustainable transport ... ...

    Abstract Making transport systems sustainable is a topic that has attracted the attention of many researchers and urban planners. The Association of Southeast Asian Nations (ASEAN) Smart Cities Network (ASCN) was initiated to develop a sustainable transport system in the ASEAN countries. A comprehensive understanding of street networks (SNs) can contribute significantly to the achievement of this initiative. Therefore, this paper measured and compared characteristics of drivable street networks (DSNs) and walkable street networks (WSNs) of the 26 ASCN pilot cities by applying multiple network metrics. The OSMnx tool was used to download and analyse WSNs and DSNs from the OpenStreetMap. The findings present the topological and geometric characteristics of WSNs and DSNs that are diverse and characterized by different factors. The cities with orthogonal street grids, high street density, intersection density, and fewer cul-de-sacs have good accessibility to reach destinations. In contrast, some other cities have more curvilinear and circuitous SNs with many missing links to other streets, which in turn are prone to traffic disruption. The study highlights the important features of SNs that have significant implications for future designs of SNs in the ASCN whose goal is to make cities smart and liveable for ASEAN members.
    Keywords cities ; geometry ; spatial data ; topology ; traffic
    Language English
    Dates of publication 2019-1016
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article
    ZDB-ID 2655790-3
    ISSN 2220-9964
    ISSN 2220-9964
    DOI 10.3390/ijgi8100459
    Database NAL-Catalogue (AGRICOLA)

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