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  1. Article ; Online: Monitorización de la Función Renal durante el Tratamiento de Hepatitis C: ¿Es realmente necesaria?

    Gonzales-Zamora, José A

    Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru

    2023  Volume 43, Issue 2, Page(s) 181–171828

    Title translation Monitoring Kidney Function during the treatment of Hepatitis C: Is it really necessary?
    MeSH term(s) Humans ; Hepatitis C/drug therapy ; Hepacivirus ; Kidney ; Antiviral Agents/adverse effects ; Hepatitis C, Chronic/drug therapy
    Chemical Substances Antiviral Agents
    Language Spanish
    Publishing date 2023-08-19
    Publishing country Peru
    Document type Journal Article
    ZDB-ID 2058591-3
    ISSN 1609-722X ; 1609-722X
    ISSN (online) 1609-722X
    ISSN 1609-722X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Clarifications on the article "knowledge, attitudes, and perception of the role of the media regarding COVID-19 in medical students from a peruvian university".

    Gonzales-Zamora, José A

    Revista peruana de medicina experimental y salud publica

    2022  Volume 39, Issue 2, Page(s) 249–250

    Title translation Precisiones sobre el artículo “Conocimientos, actitudes y percepción sobre el rol de los medios de comunicación respecto a la COVID-19 en estudiantes de medicina de una universidad peruana”.
    MeSH term(s) Humans ; Students, Medical ; COVID-19 ; Universities ; Perception ; Peru/epidemiology
    Language English
    Publishing date 2022-09-02
    Publishing country Peru
    Document type Letter
    ZDB-ID 2120092-0
    ISSN 1726-4642 ; 1726-4642
    ISSN (online) 1726-4642
    ISSN 1726-4642
    DOI 10.17843/rpmesp.2022.392.11071
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Respuesta inadecuada a la vacuna de hepatitis B en pacientes con VIH: otros factores a considerar.

    Gonzales-Zamora, Jose A

    Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru

    2020  Volume 40, Issue 2, Page(s) 202–203

    Title translation Inadequate response to the hepatitis B vaccine in HIV patients: other factors to consider.
    MeSH term(s) HIV Infections ; Hepatitis B ; Hepatitis B Antibodies ; Hepatitis B Vaccines ; Humans
    Chemical Substances Hepatitis B Antibodies ; Hepatitis B Vaccines
    Language Spanish
    Publishing date 2020-09-02
    Publishing country Peru
    Document type Letter ; Comment
    ZDB-ID 2058591-3
    ISSN 1609-722X ; 1609-722X
    ISSN (online) 1609-722X
    ISSN 1609-722X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Genes de resistencia a carbapenémicos en enterobacterias: ¿conocemos realmente la prevalencia de carbapenemasas en Perú?

    Gonzales-Zamora, Jose A

    Revista peruana de medicina experimental y salud publica

    2019  Volume 35, Issue 4, Page(s) 707–708

    Title translation Carbapenemic-resistant genes in enterobacteria: do we really know the prevalence of carbapenemases in Peru?
    MeSH term(s) Bacterial Proteins ; Carbapenems ; Enterobacteriaceae/genetics ; Peru ; Prevalence ; beta-Lactamases/genetics
    Chemical Substances Bacterial Proteins ; Carbapenems ; beta-Lactamases (EC 3.5.2.6) ; carbapenemase (EC 3.5.2.6)
    Language Spanish
    Publishing date 2019-02-06
    Publishing country Peru
    Document type Letter ; Comment
    ZDB-ID 2120092-0
    ISSN 1726-4642 ; 1726-4634
    ISSN (online) 1726-4642
    ISSN 1726-4634
    DOI 10.17843/rpmesp.2018.354.3918
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Interacciones medicamentosas en antivirales para tratamiento de la coinfección VIH/VHC en Perú.

    Gonzales-Zamora, Jose A

    Revista peruana de medicina experimental y salud publica

    2019  Volume 36, Issue 3, Page(s) 537–539

    Title translation Drug interactions in antivirals for the treatment of HIV/VHC co-infection in Peru.
    MeSH term(s) Anti-HIV Agents/administration & dosage ; Anti-HIV Agents/adverse effects ; Antiviral Agents/administration & dosage ; Antiviral Agents/adverse effects ; Coinfection ; Drug Interactions ; HIV Infections/drug therapy ; Hepatitis C/drug therapy ; Humans ; Peru
    Chemical Substances Anti-HIV Agents ; Antiviral Agents
    Language Spanish
    Publishing date 2019-12-02
    Publishing country Peru
    Document type Letter
    ZDB-ID 2120092-0
    ISSN 1726-4642 ; 1726-4634
    ISSN (online) 1726-4642
    ISSN 1726-4634
    DOI 10.17843/rpmesp.2019.363.4448
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Such a fun-guy! Is this

    Villavicencio, Aasith / Ruiz, Eloy F / Fernandez, Osiris / Fernandez, Anmary / Gonzales-Zamora, Jose A

    Clinical case reports

    2023  Volume 11, Issue 3, Page(s) e7144

    Abstract: Histoplasmosis is a neglected mycosis with high mortality in immunocompromised individuals. The diagnosis can be delayed due to nonspecific clinical manifestations and similar morphology with other organisms. A high index of suspicion is required. ...

    Abstract Histoplasmosis is a neglected mycosis with high mortality in immunocompromised individuals. The diagnosis can be delayed due to nonspecific clinical manifestations and similar morphology with other organisms. A high index of suspicion is required.
    Language English
    Publishing date 2023-03-26
    Publishing country England
    Document type Case Reports
    ZDB-ID 2740234-4
    ISSN 2050-0904
    ISSN 2050-0904
    DOI 10.1002/ccr3.7144
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Lemierre-like syndrome after soft tissue infection due to methicillin-resistant Staphylococcus aureus: A case report and literature review.

    Carreras, Xosse / Salcedo, Andrea S / Ponce-Rosas, Linda / Gonzales-Zamora, Jose A / Diaz, Nelson / Alave, Jorge

    Medicine

    2024  Volume 103, Issue 7, Page(s) e37006

    Abstract: Rationale: Lemierre-like syndrome (LLS) is characterized by bacteremia, septic thrombophlebitis of the internal jugular vein, and metastatic abscesses. In contrast to classic Lemierre syndrome, sources of infection are not related to oropharyngeal ... ...

    Abstract Rationale: Lemierre-like syndrome (LLS) is characterized by bacteremia, septic thrombophlebitis of the internal jugular vein, and metastatic abscesses. In contrast to classic Lemierre syndrome, sources of infection are not related to oropharyngeal infections, as are frequent soft tissue infections. In recent years, Staphylococcus aureus has been identified as an emergent pathogen that causes this syndrome. The mortality rate of LLS caused by this pathogen is approximately 16%. Timely diagnosis, antibiotic treatment, and infection control are the cornerstones to treat LLS. Anticoagulant therapy as adjuvant treatment remains controversial.
    Patient concerns: A 31-year-old woman from California, United States (US), was admitted to the emergency room with a history of 2 days of fever and severe throbbing pain in the left cervical region. Thorax and neck CT tomography revealed confluent cavities suggestive of septic embolism in the lungs and a filiform thrombus in the lumen of the left internal jugular vein, with moderate swelling of the soft and muscular tissues. Methicillin-resistant Staphylococcus aureus (MRSA) was isolated from the blood culture.
    Diagnosis: The thrombus in the internal jugular vein associated with cellulitis in the neck and multiple cavitary lesions in the lungs support the diagnosis of LLS caused by MRSA with septic embolization.
    Interventions: During treatment, the patient received vancomycin IV for 25 days and returned to the US with linezolid orally. In addition, assisted video-thoracoscopy and bilateral mini-thoracotomy with pleural decortication were performed for infectious source control, where 1700cc of purulent pleural fluid was drained.
    Outcomes: The patient was discharged with optimal evolution.
    Lessons: LLS should be suspected in patients with skin and soft tissue infections who develop thrombosis or metastatic infections. MRSA infections should be considered in patients from areas where this pathogen is prevalent.
    MeSH term(s) Female ; Humans ; Adult ; Lemierre Syndrome/diagnosis ; Methicillin-Resistant Staphylococcus aureus ; Soft Tissue Infections/diagnosis ; Soft Tissue Infections/therapy ; Soft Tissue Infections/complications ; Thrombophlebitis/etiology ; Thrombophlebitis/drug therapy ; Staphylococcus aureus ; Anti-Bacterial Agents/therapeutic use
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2024-02-16
    Publishing country United States
    Document type Review ; Case Reports ; Journal Article
    ZDB-ID 80184-7
    ISSN 1536-5964 ; 0025-7974
    ISSN (online) 1536-5964
    ISSN 0025-7974
    DOI 10.1097/MD.0000000000037006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Determinants of public health and interventions to address HIV infection among men who have sex with men in Miami-Dade County, Florida, USA.

    Gonzales-Zamora, Jose A / Ponce-Rosas, Linda / Martinez, Richard

    Le infezioni in medicina

    2022  Volume 30, Issue 3, Page(s) 392–402

    Abstract: Human immunodeficiency virus (HIV) among men who have sex with men (MSM) has been recognized as a public health problem in Miami-Dade County, Florida, USA. This was found to be a significant problem in our need assessment as evidenced by the HIV ... ...

    Abstract Human immunodeficiency virus (HIV) among men who have sex with men (MSM) has been recognized as a public health problem in Miami-Dade County, Florida, USA. This was found to be a significant problem in our need assessment as evidenced by the HIV incidence rate of 28.4 per 100,000 population, which is higher than the average incidence reported for the state of Florida. MSM account for the mostly affected group, reaching 59% of all the new cases. A review of the HIV determinants was conducted using an ecological framework. At the individual level, sexual abuse, alcohol, and drug consumption were identified as determinants of HIV infection in this population. Family rejection was recognized as a determinant at the interpersonal level. Connection to the gay community can function as a protective factor but it can also be possible predictor of HIV infection. Among structural factors, poverty was found to be positively associated with HIV prevalence. Additionally, we highlighted the importance of sexual health education and especially pre-exposure prophylaxis (PrEP) as protective factors. By using systems thinking tools, we designed a causal loop diagram that illustrates visually the recognized determinants of public health. Finally, we presented several studies that evaluate evidence-based interventions to improve the uptake and retention in care of PrEP in MSM. We also described existing interventions implemented in Miami-Dade County, and reported studies that may contribute to the development of new HIV preventive strategies in the future.
    Language English
    Publishing date 2022-09-01
    Publishing country Italy
    Document type Journal Article ; Review
    ZDB-ID 2041081-5
    ISSN 2532-8689 ; 1124-9390
    ISSN (online) 2532-8689
    ISSN 1124-9390
    DOI 10.53854/liim-3003-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Successful treatment with Remdesivir and corticosteroids in a patient with COVID-19-associated pneumonia: A case report.

    Gonzales-Zamora, José A / Quiroz, Tanya / Vega, Ana D

    Medwave

    2020  Volume 20, Issue 7, Page(s) e7998

    Abstract: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has rapidly spread throughout the world causing significant mortality in high risk patients with severe manifestations. To date, Remdesivir has been the only antiviral authorized by FDA as ... ...

    Title translation Tratamiento exitoso con Remdesivir y corticoides en un paciente con neumonía asociada a COVID-19: reporte de un caso.
    Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has rapidly spread throughout the world causing significant mortality in high risk patients with severe manifestations. To date, Remdesivir has been the only antiviral authorized by FDA as therapy for emergency use. One of the potential complications of this infection is cytokine storm, which optimal treatment remains unknown. We present the case of a 48-year-old man with no past medical history who presented to the hospital with dyspnea, cough, subjective fever, and diarrhea for 10 days. Nasopharyngeal PCR was positive for SARS-CoV-2. His respiratory status rapidly worsened to the point of requiring supplemental oxygen by high flow nasal cannula with FiO2 of 80%. Chest computed tomography showed confluent ground glass opacities in upper lobes accompanied by patchy airspace opacities in lower lobes bilaterally. He was started on hydroxychloroquine, which was switched to Remdesivir when it became available. Then, methylprednisolone was initiated for suspected cytokine storm. The patients oxygenation improved significantly over the following days and he was discharged home with no oxygen supplementation and saturating 96% on room air. Our case illustrates the role of Remdesivir for the treatment of severe COVID-19 pneumonia. We also observed a possible clinical benefit of corticosteroids in the context of suspected cytokine storm. Further studies are needed to evaluate this therapeutic strategy.
    MeSH term(s) Adenosine Monophosphate/analogs & derivatives ; Adenosine Monophosphate/therapeutic use ; Alanine/analogs & derivatives ; Alanine/therapeutic use ; Antiviral Agents/therapeutic use ; Betacoronavirus ; Coronavirus Infections/complications ; Coronavirus Infections/diagnosis ; Coronavirus Infections/drug therapy ; Cytokine Release Syndrome/drug therapy ; Cytokine Release Syndrome/etiology ; Glucocorticoids/therapeutic use ; Humans ; Male ; Methylprednisolone/therapeutic use ; Middle Aged ; Pandemics ; Pneumonia, Viral/complications ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/drug therapy
    Chemical Substances Antiviral Agents ; Glucocorticoids ; remdesivir (3QKI37EEHE) ; Adenosine Monophosphate (415SHH325A) ; Alanine (OF5P57N2ZX) ; Methylprednisolone (X4W7ZR7023)
    Keywords covid19
    Language English
    Publishing date 2020-08-19
    Publishing country Chile
    Document type Case Reports
    ZDB-ID 2818022-7
    ISSN 0717-6384 ; 0717-6384
    ISSN (online) 0717-6384
    ISSN 0717-6384
    DOI 10.5867/medwave.2020.07.7998
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Acute septic elbow monoarthritis with associated Neisseria gonorrhoeae bacteraemia: an uncommon presentation of an old disease.

    Piazza, Michael J / Gonzales-Zamora, Jose A

    Le infezioni in medicina

    2020  Volume 28, Issue 2, Page(s) 253–257

    Abstract: Neisseria gonorrhoeae is an uncommon present-day cause of septic arthritis. It is generally seen in the younger patient population and is often difficult to isolate in the lab. Blood cultures performed as routine work are usually negative, and when ... ...

    Abstract Neisseria gonorrhoeae is an uncommon present-day cause of septic arthritis. It is generally seen in the younger patient population and is often difficult to isolate in the lab. Blood cultures performed as routine work are usually negative, and when positive tend to be seen in the classic form of disseminated gonococcal infection. Here we report a case of acute septic monoarthritis, associated with N. gonorrhoea bacteraemia, in a 67-year-old male patient with multiple chronic comorbidities, who presented with acute pain and swelling at his left elbow, and no associated skin changes. Arthrocentesis findings were consistent with septic arthritis. Blood cultures drawn on admission grew N. gonorrhoeae. Synovial fluid culture was sterile but did exhibit Gram-negative cocci on Gram stain. The patient was started on IV antibiotics, and later underwent incision and drainage with subsequent improvement in symptoms. We thus present an unusual form of disseminated gonococcal infection in the setting of: epidemiology, physical presentation, as well as microbiologic findings. Although less common, DGI should be considered in the differential for septic join in the older adult population, and a sexual history should be obtained in all patients. This patient ultimately had an excellent outcome given his prompt presentation after symptom onset and immediate initiation of medical therapy.
    MeSH term(s) Aged ; Arthritis, Infectious/diagnosis ; Arthritis, Infectious/drug therapy ; Arthritis, Infectious/microbiology ; Bacteremia/diagnosis ; Bacteremia/drug therapy ; Elbow Joint ; Gonorrhea/diagnosis ; Gonorrhea/drug therapy ; Humans ; Male
    Language English
    Publishing date 2020-05-30
    Publishing country Italy
    Document type Case Reports ; Journal Article
    ZDB-ID 2041081-5
    ISSN 1124-9390
    ISSN 1124-9390
    Database MEDical Literature Analysis and Retrieval System OnLINE

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