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  1. Article ; Online: A non-randomised feasibility study of the Rehabilitation Potential Assessment Tool (RePAT) in frail older people in the acute healthcare setting.

    Cowley, Alison / Goldberg, Sarah E / Gordon, Adam L / Logan, Pip A

    BMC geriatrics

    2022  Volume 22, Issue 1, Page(s) 785

    Abstract: Background: Rehabilitation potential involves predicting who will benefit from rehabilitation. Decisions about rehabilitation potential must take into account personal, clinical and contextual factors, a process which is complicated in the presence of ... ...

    Abstract Background: Rehabilitation potential involves predicting who will benefit from rehabilitation. Decisions about rehabilitation potential must take into account personal, clinical and contextual factors, a process which is complicated in the presence of acute ill-health and frailty. This study aimed to evaluate the feasibility and acceptability of the Rehabilitation Potential Assessment Tool (RePAT) - a 15 item holistic, person-centred assessment tool and training package - in the acute hospital setting.
    Methods: A non-randomised feasibility study with nested semi-structured interviews explored whether RePAT was feasible and acceptable. Feasibility was tested by recruiting physiotherapy and occupational therapy participants delivering the RePAT intervention to patients alongside usual clinical care. Acceptability was tested by conducting semi-structured interviews with staff, patient and carer participants. Staff and patient characteristics were analysed using descriptive statistics. Interview data were analysed thematically. Fidelity of completed RePAT items was assessed against a priori criteria on how closely they matched tool guidance by two researchers. Mean values of the two scores were calculated. RePAT content was analysed and supported with verbatim quotes.
    Results: Six staff participants were recruited and trained. They assessed 26 patient participants using RePAT. Mean (SD) patient age was 86.16 (±6.39) years. 32% were vulnerable or mildly frail, 42% moderately frail and 26% severely or very severely frail using the Clinical Frailty Scale. Mean (SD) time to complete RePAT was 32.7 (±9.6) minutes. RePAT fidelity was good where 13 out of 15 items achieved a priori fidelity. RePAT was acceptable and tolerated by staff and patients. Staff participants reported RePAT enabled them to consider rehabilitation decisions in a more structured and consistent way. Patients and carer participants, although unable to comment directly on RePAT, reported being satisfied with their rehabilitation assessments which were found to embrace a person-centred approach.
    Conclusions: RePAT was found to be acceptable and feasible by staff, carers and patients. It allowed clinicians to make explicit their reasoning behind rehabilitation assessments and encouraged them to become more cognisant of factors which affected their clinical decision-making.
    Trial registration: ID ISRCTN31938453 . Registered 05/10/2021.
    MeSH term(s) Aged ; Aged, 80 and over ; Caregivers ; Delivery of Health Care ; Feasibility Studies ; Frail Elderly ; Frailty/diagnosis ; Humans
    Language English
    Publishing date 2022-10-07
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2059865-8
    ISSN 1471-2318 ; 1471-2318
    ISSN (online) 1471-2318
    ISSN 1471-2318
    DOI 10.1186/s12877-022-03420-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Rehabilitation potential in older people living with frailty: a systematic mapping review.

    Cowley, Alison / Goldberg, Sarah E / Gordon, Adam L / Logan, Pip A

    BMC geriatrics

    2021  Volume 21, Issue 1, Page(s) 533

    Abstract: Background: Following periods of acute ill-health and injury, older people are frequently assessed and provided with rehabilitation services. Healthcare practitioners are required to make nuanced decisions about which patients are likely to benefit from ...

    Abstract Background: Following periods of acute ill-health and injury, older people are frequently assessed and provided with rehabilitation services. Healthcare practitioners are required to make nuanced decisions about which patients are likely to benefit from and respond to rehabilitation. The clinical currency in which these decisions are transacted is through the term "rehabilitation potential". The aim of this study was to explore information about rehabilitation potential in older people to inform the development of an evidence-based assessment tool.
    Methods: A systematic mapping review was completed to describe the extent of research and the concepts underpinning rehabilitation potential. We searched Medline, CINHAL, EMBASE, AMED, PsycINFO, PEDro, Cochrane Library, Web of Science, ProQuest, Trip and EThOS from inception to December 2020. We included studies which focused on rehabilitation potential and/or assessing for rehabilitation interventions for older people with comorbidities in the hospital and community setting. Reviewer pairs independently screened articles and extracted data against the inclusion criteria. A descriptive narrative approach to analysis was taken.
    Results: 13,484 papers were identified and 49 included in the review. Rehabilitation potential was found to encompass two different but interrelated concepts of prognostication and outcome measurement. 1. Rehabilitation potential for prognostication involved the prediction of what could be achieved in programmes of rehabilitation. 2. Rehabilitation potential as an outcome measure retrospectively considered what had been achieved as a result of rehabilitation interventions. Assessments of rehabilitation potential included key domains which were largely assessed by members of the multi-disciplinary team at single time points. Limited evidence was identified which specifically considered rehabilitation potential amongst older people living with frailty.
    Conclusions: Current approaches to rehabilitation potential provide a snapshot of an individual's abilities and conditions which fail to capture the dynamic nature and fluctuations associated with frailty and rehabilitation. New approaches to measures and abilities over time are required which allow for the prognostication of outcomes and potential benefits of rehabilitation interventions for older people living with frailty.
    MeSH term(s) Aged ; Frailty ; Hospitals ; Humans ; Retrospective Studies
    Language English
    Publishing date 2021-10-07
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Systematic Review
    ZDB-ID 2059865-8
    ISSN 1471-2318 ; 1471-2318
    ISSN (online) 1471-2318
    ISSN 1471-2318
    DOI 10.1186/s12877-021-02498-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: A fully stapled technique for gastrojejunal anastomosis creation in robotic Roux-en-Y gastric bypass.

    Prager, Logan P / Huff, Mallorie L / Alfieri, Sarah E / Sujka, Joseph A

    Langenbeck's archives of surgery

    2022  Volume 407, Issue 8, Page(s) 3311–3314

    Abstract: Purpose: The purpose of this paper is to showcase a fully stapled approach to creating a gastrojejunostomy during a robot-assisted Roux-en-Y gastric bypass.: Methods: We utilize two robotic 12-mm ports, two robotic 8-mm ports, and one 8-mm assistant ... ...

    Abstract Purpose: The purpose of this paper is to showcase a fully stapled approach to creating a gastrojejunostomy during a robot-assisted Roux-en-Y gastric bypass.
    Methods: We utilize two robotic 12-mm ports, two robotic 8-mm ports, and one 8-mm assistant port. The tools used are a fenestrated bipolar forceps, vessel sealer, cadiere grasper, needle driver, and a robotic stapler. After the partial gastrectomy, the roux limb is brought up to the gastric pouch where monopolar scissors are used to create a gastrotomy and enterotomy. The gastrotomy is made just above the staple line of the gastric pouch. The enterotomy is created 2 cm distal to the roux limb's staple line. The stapler is inserted into both the gastrotomy and enterotomy to create the common channel. A 2-0 vicryl suture is used to place four interrupted sutures across the remaining enterotomy in full thickness bites. An endoscope or Visigi bougie is advanced across the anastomosis into the roux limb before the final suture. The tails of the most lateral and medial sutures are grasped and lifted towards the abdominal wall. The stapler is advanced over the approximated enterostomy while holding tension with the suture tails. The stapler is fired transversely across the suture line to seal the gastrojejunostomy. The staple line may be oversewn with silk sutures. A leak test is performed prior to completing the reconstruction with the jejunojejunostomy.
    Conclusions: A fully stapled technique of anastomosis creation may reduce operative time, standardizes the process for reproducibility, and increases consistency across operators and patients.
    Language English
    Publishing date 2022-08-05
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1423681-3
    ISSN 1435-2451 ; 1435-2443
    ISSN (online) 1435-2451
    ISSN 1435-2443
    DOI 10.1007/s00423-022-02634-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Vertebral artery dissection in relation to pregnancy: a case series and literature review.

    Rosalik, Kendal F / Havemann, Logan M / Wasickanin, Morgan E / McCaulley, Jill A / Edwards, Sarah M / Leonard, Katherine M

    AJOG global reports

    2023  Volume 3, Issue 4, Page(s) 100281

    Abstract: Cervical artery dissection is an uncommon condition for which pregnancy and postpartum states confer increased risk. Although the majority of patients with this condition fully recover, including resolution of the dissection on imaging, long-term ... ...

    Abstract Cervical artery dissection is an uncommon condition for which pregnancy and postpartum states confer increased risk. Although the majority of patients with this condition fully recover, including resolution of the dissection on imaging, long-term sequelae include a variety of cardiovascular conditions that may be associated with high rates of morbidity and mortality. Here, we review 2 cases of vertebral artery dissection in relation to pregnancy. Our first case will review the management of a pregnant patient with a history of vertebral artery dissection; whereas our second case reviews a presentation of postpartum vertebral artery dissection. Providers should maintain a high suspicion of cervical artery dissection in pregnant and postpartum patients presenting with headache and neck pain.
    Language English
    Publishing date 2023-10-14
    Publishing country United States
    Document type Case Reports
    ISSN 2666-5778
    ISSN (online) 2666-5778
    DOI 10.1016/j.xagr.2023.100281
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: A novel bluetongue virus serotype 2 strain isolated from a farmed Florida white-tailed deer (Odocoileus virginianus) arose from reassortment of gene segments derived from co-circulating serotypes in the Southeastern USA.

    Viadanna, Pedro H O / Surphlis, Austin / Cheng, An-Chi / Dixon, Catherine E / Meisner, Sarah / Wilson, Kristen N / White, Zoe S / DeRuyter, Emily / Logan, Tracey D / Krauer, Juan M C / Lednicky, John A / Wisely, Samantha M / Subramaniam, Kuttichantran

    Virus genes

    2024  Volume 60, Issue 1, Page(s) 100–104

    Abstract: Bluetongue disease is a reportable animal disease that affects wild and farmed ruminants, including white-tailed deer (WTD). This report documents the clinical findings, ancillary diagnostics, and genomic characterization of a novel reassortant ... ...

    Abstract Bluetongue disease is a reportable animal disease that affects wild and farmed ruminants, including white-tailed deer (WTD). This report documents the clinical findings, ancillary diagnostics, and genomic characterization of a novel reassortant bluetongue virus serotype 2 (BTV-2) strain isolated from a dead Florida farmed WTD in 2022. Our analyses support that this BTV-2 strain likely stemmed from the acquisition of genome segments from co-circulating BTV strains in Florida and Louisiana. In addition, our analyses also indicate that genetically uncharacterized BTV strains may be circulating in the Southeastern USA; however, the identity and reassortant status of these BTV strains cannot be determined based on the VP2 and VP5 genome sequences. Hence, continued surveillance based on complete genome characterization is needed to understand the genetic diversity of BTV strains in this region and the potential threat they may pose to the health of deer and other ruminants.
    MeSH term(s) Animals ; Florida ; Deer ; Bluetongue virus/genetics ; Serogroup
    Language English
    Publishing date 2024-01-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 639496-6
    ISSN 1572-994X ; 0920-8569
    ISSN (online) 1572-994X
    ISSN 0920-8569
    DOI 10.1007/s11262-023-02047-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Disruption of Aldehyde Dehydrogenase 2 protects against bacterial infection.

    Berry, Samuel B / Espich, Scott / Thuong, Nguyen T T / Chang, Xuling / Dorajoo, Rajkumar / Khor, Chiea-Chuen / Heng, Chew-Kiat / Yuan, Jian-Min / Fox, Douglas / Anaya-Sanchez, Andrea / Tenney, Logan / Chang, Christopher J / Kotov, Dmitri I / Vance, Russell E / Dunstan, Sarah J / Darwin, K Heran / Stanley, Sarah A

    bioRxiv : the preprint server for biology

    2023  

    Abstract: The : One sentence summary: Aldehydes produced by host cells contribute to the control of bacterial infections. ...

    Abstract The
    One sentence summary: Aldehydes produced by host cells contribute to the control of bacterial infections.
    Language English
    Publishing date 2023-08-26
    Publishing country United States
    Document type Preprint
    DOI 10.1101/2023.08.24.554661
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Remote cameras capture dung burial by burrowing cricket

    Zeitler, Emma F. / Lashley, Marcus A. / Blanc, Ava / Davis, Logan R. / Dill, Sarah E. / McGehee, Olivia H. / McLean, Blair A. / Smith, Elijah C.

    Food Webs. 2023 Sept., v. 36 p.e00301-

    2023  

    Abstract: Animal dung holds an important role in the nutrient cycle of nearly every ecosystem on Earth. It also acts as an ephemeral resource for invertebrate communities and has facilitated the specialization of many life history strategies. Most ecosystem ... ...

    Abstract Animal dung holds an important role in the nutrient cycle of nearly every ecosystem on Earth. It also acts as an ephemeral resource for invertebrate communities and has facilitated the specialization of many life history strategies. Most ecosystem functions associated with dung are linked to burial - a process most often attributed to dung beetles. However, identifying other organisms that contribute to dung burial is important to understand how communities provide this ecosystem service. During a trail camera experiment intended to monitor dung beetle behavior, we observed an unidentified species of cricket burying dung pellets underground. We were unable to find previous documentation of dung-burying behavior for this animal group, raising questions of how common or extensive this behavior is. Particularly under the threat of global insect declines, understanding which species are responsible for key processes may be crucial to maintaining ecosystem function and resilience. Additionally, this experiment exemplifies how camera traps can be used in nontraditional applications to observe and monitor unique events, behaviors, and processes, such as the decay of ephemeral resource patches and insect behavior.
    Keywords Orthoptera ; cameras ; dung beetles ; ecological function ; ecosystem services ; ecosystems ; feces ; insect behavior ; invertebrates ; life history ; Remote cameras ; Ephemeral resource ; Burrowing cricket
    Language English
    Dates of publication 2023-09
    Publishing place Elsevier Inc.
    Document type Article ; Online
    ISSN 2352-2496
    DOI 10.1016/j.fooweb.2023.e00301
    Database NAL-Catalogue (AGRICOLA)

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  8. Article ; Online: Clinical Characterization of Juvenile Fibromyalgia in a Multicenter Cohort of Adolescents Enrolled in a Randomized Clinical Trial.

    Lynch-Jordan, Anne M / Connelly, Mark / Guite, Jessica W / King, Christopher / Goldstein-Leever, Alana / Logan, Deirdre E / Nelson, Sarah / Stinson, Jennifer N / Ting, Tracy V / Wakefield, Emily O / Williams, Amy E / Williams, Sara E / Kashikar-Zuck, Susmita

    Arthritis care & research

    2023  Volume 75, Issue 8, Page(s) 1795–1803

    Abstract: Objective: Juvenile fibromyalgia (JFM) is a complex chronic pain condition that remains poorly understood. The study aimed to expand the clinical characterization of JFM in a large representative sample of adolescents with JFM and identify psychological ...

    Abstract Objective: Juvenile fibromyalgia (JFM) is a complex chronic pain condition that remains poorly understood. The study aimed to expand the clinical characterization of JFM in a large representative sample of adolescents with JFM and identify psychological factors that predict pain interference.
    Methods: Participants were 203 adolescents (ages 12-17 years) who completed baseline assessments for the multisite Fibromyalgia Integrative Training for Teens (FIT Teens) randomized control trial. Participants completed the Pain and Symptom Assessment Tool, which includes a Widespread Pain Index (WPI; 0-18 pain locations) and Symptom Severity checklist of associated somatic symptoms (SS; 0-12) based on the 2010 American College of Rheumatology criteria for fibromyalgia. Participants also completed self-report measures of pain intensity, functional impairment, and psychological functioning.
    Results: Participants endorsed a median of 11 painful body sites (WPI score) and had a median SS score of 9. Fatigue and nonrestorative sleep were prominent features and rated as moderate to severe by 85% of participants. Additionally, neurologic, autonomic, gastroenterologic, and psychological symptoms were frequently endorsed. The WPI score was significantly correlated with pain intensity and catastrophizing, while SS scores were associated with pain intensity and all domains of physical and psychological functioning. Depressive symptoms, fatigue, and pain catastrophizing predicted severity of pain impairment.
    Conclusion: JFM is characterized by chronic widespread pain with fatigue, nonrestorative sleep, and other somatic symptoms. However, how diffusely pain is distributed appears less important to clinical outcomes and impairment than other somatic and psychological factors, highlighting the need for a broader approach to the assessment and treatment of JFM.
    MeSH term(s) Humans ; Adolescent ; Fibromyalgia/diagnosis ; Fibromyalgia/epidemiology ; Fibromyalgia/therapy ; Medically Unexplained Symptoms ; Chronic Pain/diagnosis ; Chronic Pain/therapy ; Fatigue/complications ; Catastrophization/diagnosis
    Language English
    Publishing date 2023-02-16
    Publishing country United States
    Document type Randomized Controlled Trial ; Multicenter Study ; Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 645059-3
    ISSN 2151-4658 ; 0893-7524 ; 2151-464X
    ISSN (online) 2151-4658
    ISSN 0893-7524 ; 2151-464X
    DOI 10.1002/acr.25077
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Intravitreal Steroid Implants in the Management of Retinal Disease and Uveitis.

    Logan, Sarah A / Weng, Christina Y / Carvounis, Petros E

    International ophthalmology clinics

    2016  Volume 56, Issue 4, Page(s) 127–149

    MeSH term(s) Disease Management ; Drug Implants ; Glucocorticoids/administration & dosage ; Humans ; Intravitreal Injections ; Retinal Diseases/drug therapy ; Uveitis/drug therapy
    Chemical Substances Drug Implants ; Glucocorticoids
    Language English
    Publishing date 2016-09-07
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 207382-1
    ISSN 1536-9617 ; 0020-8167
    ISSN (online) 1536-9617
    ISSN 0020-8167
    DOI 10.1097/IIO.0000000000000132
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: A feasibility study to assess the design of a multicentre randomized controlled trial of the clinical and cost-effectiveness of a caregiving intervention for people following hip fracture surgery.

    Smith, Toby / Clark, Lucy / Khoury, Reema / Man, Mei-See / Hanson, Sarah / Welsh, Allie / Clark, Allan / Hopewell, Sally / Pfeiffer, Klaus / Logan, Pip / Crotty, Maria / Costa, Matthew / Lamb, Sarah E

    Bone & joint open

    2021  Volume 2, Issue 11, Page(s) 909–920

    Abstract: Aims: This study aims to assess the feasibility of conducting a pragmatic, multicentre randomized controlled trial (RCT) to test the clinical and cost-effectiveness of an informal caregiver training programme to support the recovery of people following ... ...

    Abstract Aims: This study aims to assess the feasibility of conducting a pragmatic, multicentre randomized controlled trial (RCT) to test the clinical and cost-effectiveness of an informal caregiver training programme to support the recovery of people following hip fracture surgery.
    Methods: This will be a mixed-methods feasibility RCT, recruiting 60 patients following hip fracture surgery and their informal caregivers. Patients will be randomized to usual NHS care, versus usual NHS care plus a caregiver-patient dyad training programme (HIP HELPER). This programme will comprise of three, one-hour, one-to-one training sessions for the patient and caregiver, delivered by a nurse, physiotherapist, or occupational therapist. Training will be delivered in the hospital setting pre-patient discharge. It will include practical skills for rehabilitation such as: transfers and walking; recovery goal setting and expectations; pacing and stress management techniques; and introduction to the HIP HELPER Caregiver Workbook, which provides information on recovery, exercises, worksheets, and goal-setting plans to facilitate a 'good' recovery. After discharge, patients and caregivers will be supported in delivering rehabilitation through three telephone coaching sessions. Data, collected at baseline and four months post-randomization, will include: screening logs, intervention logs, fidelity checklists, quality assurance monitoring visit data, and clinical outcomes assessing quality of life, physical, emotional, adverse events, and resource use outcomes. The acceptability of the study intervention and RCT design will be explored through qualitative methods with 20 participants (patients and informal caregivers) and 12 health professionals.
    Discussion: A multicentre recruitment approach will provide greater external validity across population characteristics in England. The mixed-methods approach will permit in-depth examination of the intervention and trial design parameters. The findings will inform whether and how a definitive trial may be undertaken to test the effectiveness of this caregiver intervention for patients after hip fracture surgery. Cite this article:
    Language English
    Publishing date 2021-11-09
    Publishing country England
    Document type Journal Article
    ISSN 2633-1462
    ISSN (online) 2633-1462
    DOI 10.1302/2633-1462.211.BJO-2021-0136
    Database MEDical Literature Analysis and Retrieval System OnLINE

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