LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 56

Search options

  1. Book ; Thesis: Quantitative Analyse von MHC-Klasse-I-Molekülen in kolorektalen Karzinomen und Identifizierung tumorassoziierter MHC-gebundener Peptide

    Eberle, Ute Erna

    2005  

    Author's details vorgelegt von Ute Erna Eberle
    Language German
    Size IV, 115 S. : Ill., graph. Darst.
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Tübingen, Univ., Diss., 2005
    HBZ-ID HT014976592
    Database Catalogue ZB MED Medicine, Health

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2007 D 319 order for loan Magazin

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Book ; Thesis: Zwangserkrankungen im Kindes- und Jugendalter

    Eberle, Ute

    Symptomatik, Verlauf, Prognose

    1988  

    Size 143 S. : graph. Darst.
    Document type Book ; Thesis
    Thesis / German Habilitation thesis München, Univ., Diss., 1988
    HBZ-ID HT003326979
    Database Catalogue ZB MED Medicine, Health

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    89 D 4235 order for loan Magazin

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article ; Online: Detection and viral RNA shedding of SARS-CoV-2 in respiratory specimens relative to symptom onset among COVID-19 patients in Bavaria, Germany - Addendum.

    Woudenberg, Tom / Eberle, Ute / Marosevic, Durdica / Liebl, Bernhard / Ackermann, Nikolaus / Katz, Katharina / Sing, Andreas

    Epidemiology and infection

    2021  Volume 149, Page(s) e167

    Language English
    Publishing date 2021-07-26
    Publishing country England
    Document type Journal Article ; Published Erratum
    ZDB-ID 632982-2
    ISSN 1469-4409 ; 0950-2688
    ISSN (online) 1469-4409
    ISSN 0950-2688
    DOI 10.1017/S095026882100159X
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Un I Zs.271: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article ; Online: Detection and viral RNA shedding of SARS-CoV-2 in respiratory specimens relative to symptom onset among COVID-19 patients in Bavaria, Germany.

    Woudenberg, Tom / Eberle, Ute / Marosevic, Durdica / Liebl, Bernhard / Ackermann, Nikolaus / Katz, Katharina / Sing, Andreas

    Epidemiology and infection

    2021  Volume 149, Page(s) e150

    Abstract: We assessed severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) reverse transcriptase-polymerase chain reaction (RT-PCR) diagnostic sensitivity and cycle threshold (Ct) values relative to symptom onset in symptomatic coronavirus disease-2019 ( ... ...

    Abstract We assessed severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) reverse transcriptase-polymerase chain reaction (RT-PCR) diagnostic sensitivity and cycle threshold (Ct) values relative to symptom onset in symptomatic coronavirus disease-2019 (COVID-19) patients from Bavaria, Germany, of whom a subset was repeatedly tested. Locally weighted scatterplot smoothing method was used to assess the relationship between symptom onset and Ct-values. Kaplan-Meier plots were used to visualise the empirical probability of detecting viral ribonucleic acid (RNA) over time and estimate the time until clearance of viral RNA among the repeatedly tested patients. Among 721 reported COVID-19 cases, the viral RNA was detected in specimens taken between three days before and up to 48 days after symptom onset. The mean Ct-value was 28.6 (95% confidence interval (CI) 28.2-29.0) with the lowest mean Ct-value (26.2) observed two days after symptom onset. Up to 7 days after symptom onset, the diagnostic sensitivity of the RT-PCR among repeatedly sampled patients (n = 208) remained above 90% and decreased to 50% at day 12 (95% CI 10.5-21.5). Our data provide valuable estimates to optimise the timing of sampling of individuals for SARS-CoV-2 detection. A considerable proportion of specimens sampled before symptom onset had Ct-values comparable with Ct-values after symptom onset, suggesting the probability of presymptomatic transmission.
    MeSH term(s) Adolescent ; Adult ; Aged ; Asymptomatic Infections ; COVID-19/diagnosis ; COVID-19/virology ; Child ; Child, Preschool ; Female ; Germany ; Humans ; Infant ; Male ; Middle Aged ; Nasopharynx/virology ; RNA, Viral/isolation & purification ; Reverse Transcriptase Polymerase Chain Reaction ; SARS-CoV-2/isolation & purification ; Sputum/virology ; Time Factors ; Virus Shedding ; Young Adult
    Chemical Substances RNA, Viral
    Language English
    Publishing date 2021-06-23
    Publishing country England
    Document type Journal Article
    ZDB-ID 632982-2
    ISSN 1469-4409 ; 0950-2688
    ISSN (online) 1469-4409
    ISSN 0950-2688
    DOI 10.1017/S0950268821001345
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Un I Zs.271: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article ; Online: Reciprocal circulation pattern of SARS-CoV-2 and influenza viruses during the influenza seasons 2019/2020 and 2020/2021 in the Bavarian Influenza Sentinel (Germany) - CORRIGENDUM.

    Heinzinger, Susanne / Eberle, Ute / Angermeier, Hildegard / Flechsler, Jennifer / Konrad, Regina / Dangel, Alexandra / Berger, Carola / Sprenger, Annika / Hepner, Sabrina / Biere, Barbara / Liebl, Bernhard / Ackermann, Nikolaus / Sing, Andreas

    Epidemiology and infection

    2022  Volume 150, Page(s) e24

    Language English
    Publishing date 2022-02-11
    Publishing country England
    Document type Journal Article ; Published Erratum
    ZDB-ID 632982-2
    ISSN 1469-4409 ; 0950-2688
    ISSN (online) 1469-4409
    ISSN 0950-2688
    DOI 10.1017/S0950268821002466
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Un I Zs.271: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Book ; Online: GrippeWeb-Wochenbericht KW 15

    Buchholz, Udo / Buda, Silke / Eberle, Caroline / Hoffmeister, Melanie / Lehfeld, Ann-Sophie / Loenenbach, Anna / Michel, Janine / Prahm, Kerstin / Preuß, Ute / Haas, Walter / AMELAG-Team

    2024  

    Abstract: Die Aktivität akuter Atemwegserkrankungen (ARE-Inzidenz) in der Bevölkerung ist in der 15. KW 2024 im Vergleich zur Vorwoche insgesamt relativ stabil geblieben und lag bei rund 4.700 ARE pro 100.000 Einw. (Vorwoche: 4.600). Die Inzidenz der ... ...

    Abstract Die Aktivität akuter Atemwegserkrankungen (ARE-Inzidenz) in der Bevölkerung ist in der 15. KW 2024 im Vergleich zur Vorwoche insgesamt relativ stabil geblieben und lag bei rund 4.700 ARE pro 100.000 Einw. (Vorwoche: 4.600). Die Inzidenz der grippeähnlichen Erkrankungen (ILI) ist im Vergleich zur Vorwoche ebenfalls stabil bei rund 900 ILI pro 100.000 Einw. geblieben. Die Gesamt-ARE-Inzidenz befand sich im mittleren und die Gesamt-ILI-Inzidenz im unteren Wertebereich der vorpandemischen Jahre zu dieser Zeit. Die geschätzte COVID-19-Inzidenz in der Bevölkerung basierend auf Angaben der GrippeWeb-Teilnehmenden lag in der 15. KW deutlich unter 100 COVID-19-Erkrankungen pro 100.000 Einw. In der virologischen Überwachung in der Bevölkerung (GrippeWeb-Plus) wurden seit der 12. KW 2024 hauptsächlich Rhino-/Enteroviren und humane saisonale Coronaviren (hCoV) nachgewiesen sowie zu niedrigeren Anteilen auch andere Erreger. Gemäß den Daten aus der Arbeitsgemeinschaft Influenza endete die Grippewelle mit der 12. KW 2024, die RSV-Welle endete mit der 10. KW 2024. Die für die Bevölkerung in Deutschland geschätzten Inzidenzen für die 15. KW 2024 beruhen auf den Angaben von 7.321 GrippeWeb-Teilnehmenden, von diesen meldeten 317 eine ARE und 58 eine ILI (Datenstand: 16.4.2024, 0:00 Uhr). Durch Nachmeldungen, die bis zu vier Wochen lang möglich sind, können sich noch Änderungen ergeben.
    Keywords 610 Medizin und Gesundheit ; ddc:610
    Language German
    Publishing date 2024-04-19
    Publisher Robert Koch-Institut
    Publishing country de
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  7. Article ; Online: Virological COVID-19 surveillance in Bavaria, Germany suggests no SARS-CoV-2 spread prior to the first German case in January 2020.

    Eberle, Ute / Heinzinger, Susanne / Konrad, Regina / Wimmer, Clara / Liebl, Bernhard / Katz, Katharina / Ackermann, Nikolaus / Sing, Andreas

    Infection

    2021  Volume 49, Issue 5, Page(s) 1029–1032

    Abstract: The Bavarian Influenza Sentinel (BIS) monitors the annual influenza season by combining virological and epidemiological data. The 2019/2020 influenza season overlapped with the beginning COVID-19 pandemic thus allowing to investigate whether there was an ...

    Abstract The Bavarian Influenza Sentinel (BIS) monitors the annual influenza season by combining virological and epidemiological data. The 2019/2020 influenza season overlapped with the beginning COVID-19 pandemic thus allowing to investigate whether there was an unnoticed spread of SARS-CoV-2 among outpatients with acute respiratory infections in the community prior to the first COVID-19 cluster in Bavaria. Therefore, we retrospectively analysed oropharyngeal swabs obtained in BIS between calendar week (CW) 39 in 2019 and CW 14 in 2020 for the presence of SARS-CoV-2 RNA by RT-PCR. 610 of all 1376 BIS swabs-contained sufficient material to test for SARS-CoV-2, among them 260 oropharyngeal swabs which were collected prior to the first notified German COVID-19 case in CW 04/2020. In none of these swabs SARS-CoV-2 RNA was detected suggesting no SARS-CoV-2 spread prior to late January 2020 in Bavaria.
    MeSH term(s) COVID-19 ; Germany/epidemiology ; Humans ; Pandemics ; RNA, Viral ; Retrospective Studies ; SARS-CoV-2
    Chemical Substances RNA, Viral
    Language English
    Publishing date 2021-04-23
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 185104-4
    ISSN 1439-0973 ; 0300-8126 ; 0173-2129
    ISSN (online) 1439-0973
    ISSN 0300-8126 ; 0173-2129
    DOI 10.1007/s15010-021-01611-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 881: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 528: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  8. Article ; Online: Comparison of nine different commercially available molecular assays for detection of SARS-CoV-2 RNA.

    Eberle, Ute / Wimmer, Clara / Huber, Ingrid / Neubauer-Juric, Antonie / Valenza, Giuseppe / Ackermann, Nikolaus / Sing, Andreas

    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology

    2021  Volume 40, Issue 6, Page(s) 1303–1308

    Abstract: To face the COVID-19 pandemic, the need for fast and reliable diagnostic assays for the detection of SARS-CoV-2 is immense. We describe our laboratory experiences evaluating nine commercially available real-time RT-PCR assays. We found that assays ... ...

    Abstract To face the COVID-19 pandemic, the need for fast and reliable diagnostic assays for the detection of SARS-CoV-2 is immense. We describe our laboratory experiences evaluating nine commercially available real-time RT-PCR assays. We found that assays differed considerably in performance and validation before routine use is mandatory.
    MeSH term(s) COVID-19/diagnosis ; COVID-19 Nucleic Acid Testing/standards ; COVID-19 Testing/methods ; Humans ; Molecular Diagnostic Techniques/standards ; RNA, Viral/isolation & purification ; Reagent Kits, Diagnostic/standards ; Real-Time Polymerase Chain Reaction/standards ; SARS-CoV-2
    Chemical Substances RNA, Viral ; Reagent Kits, Diagnostic
    Language English
    Publishing date 2021-01-29
    Publishing country Germany
    Document type Comparative Study ; Journal Article
    ZDB-ID 603155-9
    ISSN 1435-4373 ; 0934-9723 ; 0722-2211
    ISSN (online) 1435-4373
    ISSN 0934-9723 ; 0722-2211
    DOI 10.1007/s10096-021-04159-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1732: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  9. Article ; Online: Endothelial-platelet interactions in influenza-induced pneumonia: A potential therapeutic target.

    Rommel, Marcel G E / Milde, Christian / Eberle, Regina / Schulze, Harald / Modlich, Ute

    Anatomia, histologia, embryologia

    2019  Volume 49, Issue 5, Page(s) 606–619

    Abstract: Every year, influenza viruses spread around the world, infecting the respiratory systems of countless humans and animals, causing illness and even death. Severe influenza infection is associated with pulmonary epithelial damage and endothelial ... ...

    Abstract Every year, influenza viruses spread around the world, infecting the respiratory systems of countless humans and animals, causing illness and even death. Severe influenza infection is associated with pulmonary epithelial damage and endothelial dysfunction leading to acute lung injury (ALI). There is evidence that an aggressive cytokine storm and cell damage in lung capillaries as well as endothelial/platelet interactions contribute to vascular leakage, pro-thrombotic milieu and infiltration of immune effector cells. To date, treatments for ALI caused by influenza are limited to antiviral drugs, active ventilation or further symptomatic treatments. In this review, we summarize the mechanisms of influenza-mediated pathogenesis, permissive animal models and histopathological changes of lung tissue in both mice and men and compare it with histological and electron microscopic data from our own group. We highlight the molecular and cellular interactions between pulmonary endothelium and platelets in homeostasis and influenza-induced pathogenesis. Finally, we discuss novel therapeutic targets on platelets/endothelial interaction to reduce or resolve ALI.
    MeSH term(s) Animals ; Blood Platelets/metabolism ; Blood Platelets/physiology ; Disease Models, Animal ; Endothelium/physiology ; Humans ; Influenza, Human/blood ; Influenza, Human/pathology ; Orthomyxoviridae/classification ; Orthomyxoviridae/genetics ; Orthomyxoviridae Infections/blood ; Orthomyxoviridae Infections/pathology ; Orthomyxoviridae Infections/veterinary ; Platelet Activation ; Pulmonary Alveoli/pathology
    Language English
    Publishing date 2019-12-02
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 537922-2
    ISSN 1439-0264 ; 0340-2096 ; 0044-4294
    ISSN (online) 1439-0264
    ISSN 0340-2096 ; 0044-4294
    DOI 10.1111/ahe.12521
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.B 1221: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  10. Article: Endothelial–platelet interactions in influenza‐induced pneumonia: A potential therapeutic target

    Rommel, Marcel G. E / Milde, Christian / Eberle, Regina / Schulze, Harald / Modlich, Ute

    Anatomia, histologia, embryologia. 2020 Sept., v. 49, no. 5

    2020  

    Abstract: Every year, influenza viruses spread around the world, infecting the respiratory systems of countless humans and animals, causing illness and even death. Severe influenza infection is associated with pulmonary epithelial damage and endothelial ... ...

    Abstract Every year, influenza viruses spread around the world, infecting the respiratory systems of countless humans and animals, causing illness and even death. Severe influenza infection is associated with pulmonary epithelial damage and endothelial dysfunction leading to acute lung injury (ALI). There is evidence that an aggressive cytokine storm and cell damage in lung capillaries as well as endothelial/platelet interactions contribute to vascular leakage, pro‐thrombotic milieu and infiltration of immune effector cells. To date, treatments for ALI caused by influenza are limited to antiviral drugs, active ventilation or further symptomatic treatments. In this review, we summarize the mechanisms of influenza‐mediated pathogenesis, permissive animal models and histopathological changes of lung tissue in both mice and men and compare it with histological and electron microscopic data from our own group. We highlight the molecular and cellular interactions between pulmonary endothelium and platelets in homeostasis and influenza‐induced pathogenesis. Finally, we discuss novel therapeutic targets on platelets/endothelial interaction to reduce or resolve ALI.
    Keywords cytokines ; death ; electron microscopy ; endothelium ; histology ; histopathology ; homeostasis ; influenza ; lungs ; pathogenesis ; pneumonia ; therapeutics
    Language English
    Dates of publication 2020-09
    Size p. 606-619.
    Publishing place John Wiley & Sons, Ltd
    Document type Article
    Note NAL-light ; JOURNAL ARTICLE
    ZDB-ID 537922-2
    ISSN 1439-0264 ; 0340-2096 ; 0044-4294
    ISSN (online) 1439-0264
    ISSN 0340-2096 ; 0044-4294
    DOI 10.1111/ahe.12521
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

    In stock of ZB MED Bonn / Germany

    Z 960 c: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

To top