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  1. Article ; Online: Is there any kind of relationship between alpha-1 antitrypsin levels and lung function parameters?

    Hernández-Pérez, José María / López-Charry, Claudia Viviana

    Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia

    2023  Volume 49, Issue 1, Page(s) e20220432

    MeSH term(s) Humans ; alpha 1-Antitrypsin/genetics ; Lung ; alpha 1-Antitrypsin Deficiency ; Phenotype
    Chemical Substances alpha 1-Antitrypsin
    Language Portuguese
    Publishing date 2023-02-13
    Publishing country Brazil
    Document type Letter
    ZDB-ID 2223157-2
    ISSN 1806-3756 ; 1806-3713
    ISSN (online) 1806-3756
    ISSN 1806-3713
    DOI 10.36416/1806-3756/e20220432
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Is the determination of C-reactive protein really necessary in the diagnosis of Alpha-1 antitrypsin deficiency?

    Hernández-Pérez, José María / López-Charry, Claudia Viviana

    The clinical respiratory journal

    2022  Volume 16, Issue 5, Page(s) 420–422

    MeSH term(s) C-Reactive Protein ; Humans ; Phenotype ; alpha 1-Antitrypsin ; alpha 1-Antitrypsin Deficiency/diagnosis ; alpha 1-Antitrypsin Deficiency/genetics
    Chemical Substances alpha 1-Antitrypsin ; C-Reactive Protein (9007-41-4)
    Language English
    Publishing date 2022-05-17
    Publishing country England
    Document type Letter
    ZDB-ID 2442214-9
    ISSN 1752-699X ; 1752-6981
    ISSN (online) 1752-699X
    ISSN 1752-6981
    DOI 10.1111/crj.13494
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Alpha-1 antitrypsin deficiency: PI*M

    Hernández-Pérez, José María / López-Charry, Claudia Viviana

    Pediatrics international : official journal of the Japan Pediatric Society

    2022  Volume 64, Issue 1, Page(s) e15269

    MeSH term(s) Humans ; Mutation ; Phenotype ; alpha 1-Antitrypsin Deficiency/complications ; alpha 1-Antitrypsin Deficiency/diagnosis ; alpha 1-Antitrypsin Deficiency/epidemiology
    Language English
    Publishing date 2022-10-14
    Publishing country Australia
    Document type Letter
    ZDB-ID 1470376-2
    ISSN 1442-200X ; 1328-8067
    ISSN (online) 1442-200X
    ISSN 1328-8067
    DOI 10.1111/ped.15269
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 848: Show issues Location:
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  4. Article ; Online: The impact of alpha-1 antitrypsin deficiency alleles on lung cancer survival.

    Hernández-Pérez, José María / Ramos-Izquierdo, Carolina / Figueira-Gonçalves, Juan Marco / Martínez-Bugallo, Francisco / Ramallo-Fariña, Yolanda / Pérez-Negrín, Lorenzo

    Translational cancer research

    2024  Volume 13, Issue 2, Page(s) 1125–1130

    Abstract: Different studies have shown that carrying an alpha-1 antitrypsin (AAT) deficiency allele is an independent risk factor for developing lung cancer (LC). However, to date, little is known regarding whether carrying a deficiency allele may be a prognostic ... ...

    Abstract Different studies have shown that carrying an alpha-1 antitrypsin (AAT) deficiency allele is an independent risk factor for developing lung cancer (LC). However, to date, little is known regarding whether carrying a deficiency allele may be a prognostic factor in the evolution of LC. A prospective observational study was carried out which consecutively included patients diagnosed with LC in University Hospital "Nuestra Señora de Candelaria" between December 2017 and August 2020. A blood sample was taken from each of the patients in order to determine both AAT serum concentration and genotype. Based on AAT genotype, patients were divided into the deficiency (
    Language English
    Publishing date 2024-02-22
    Publishing country China
    Document type Journal Article
    ZDB-ID 2901601-0
    ISSN 2219-6803 ; 2218-676X
    ISSN (online) 2219-6803
    ISSN 2218-676X
    DOI 10.21037/tcr-23-743
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: In Situ Use of Mining Substrates for Wetland Construction: Results of a Pilot Experiment.

    Hernández-Pérez, Carmen / Martínez-López, Salvadora / Martínez-Sánchez, María José / Martínez-Martínez, Lucia Belén / García-Lorenzo, María Luz / Perez Sirvent, Carmen

    Plants (Basel, Switzerland)

    2024  Volume 13, Issue 8

    Abstract: This paper evaluates an experimental wetland as part of a pilot soil reclamation project in a mining area. The wetland was constructed using materials of mining origin from the area; most reactive materials of acid pH were stabilised using limestone ... ...

    Abstract This paper evaluates an experimental wetland as part of a pilot soil reclamation project in a mining area. The wetland was constructed using materials of mining origin from the area; most reactive materials of acid pH were stabilised using limestone filler. The study selected macrophytes that are tolerant to potentially toxic elements (PTEs) and resistant to salinity, namely
    Language English
    Publishing date 2024-04-22
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2704341-1
    ISSN 2223-7747
    ISSN 2223-7747
    DOI 10.3390/plants13081161
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Alpha-1 Antitrypsin Deficiency and SERPINA1 Variants Could Play a Role in Asthma Exacerbations.

    Hernández-Pérez, José M / Martín-González, Elena / González-Carracedo, Mario A

    Archivos de bronconeumologia

    2023  Volume 59, Issue 7, Page(s) 416–417

    MeSH term(s) Humans ; alpha 1-Antitrypsin Deficiency/complications ; alpha 1-Antitrypsin Deficiency/genetics ; alpha 1-Antitrypsin/genetics ; Asthma/etiology
    Chemical Substances alpha 1-Antitrypsin ; SERPINA1 protein, human
    Language Spanish
    Publishing date 2023-02-28
    Publishing country Spain
    Document type Editorial
    ZDB-ID 733126-5
    ISSN 1579-2129 ; 0300-2896
    ISSN (online) 1579-2129
    ISSN 0300-2896
    DOI 10.1016/j.arbres.2023.02.016
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 2655: Show issues Location:
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  7. Book ; Online: Elda: ciudad y territorio

    Blasco Sánchez, María Del Carmen / Martínez Pérez, Francisco Juan / Gascón Hernández, Ana Mª / Deltoro Soto, Julia / Novella Abril, Inés / Galán Vivas, Juan José

    (Académica)

    2023  

    Series title Académica
    Keywords Architecture
    Language Spanish
    Size 1 electronic resource (238 pages)
    Publisher Universitat Politècnica de València Editorial
    Publishing place Valencia
    Document type Book ; Online
    Note Spanish
    HBZ-ID HT030378479
    ISBN 9788413960906 ; 8413960908
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  8. Article: Molecular characterization of

    Hernández-Pérez, José M / González Carracedo, Mario A / García, Angelines Concepción / Pérez, José A Pérez

    Frontiers in pediatrics

    2022  Volume 10, Page(s) 985892

    Abstract: Alpha-1-antitrypsin deficiency (AATD) is a heritable condition that predisposes to respiratory and hepatic complications. Screenings in East Asia human populations for the AATD alleles most commonly found among Caucasians have yielded poor outcomes. ... ...

    Abstract Alpha-1-antitrypsin deficiency (AATD) is a heritable condition that predisposes to respiratory and hepatic complications. Screenings in East Asia human populations for the AATD alleles most commonly found among Caucasians have yielded poor outcomes. Serum alpha-1-antitrypsin (AAT) levels, AAT phenotypes, and sequences of
    Language English
    Publishing date 2022-09-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2711999-3
    ISSN 2296-2360
    ISSN 2296-2360
    DOI 10.3389/fped.2022.985892
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Hybrid Multiobjective Optimization Using Deterministic and Metaheuristic Techniques for Flowback Water Reusing in Hydraulic Fracturing Processes

    Hernández-Pérez, Luis Germán / Lira-Barragán, Luis Fernando / Ponce-Ortega, José María

    Industrial & engineering chemistry process design and development. 2020 July 31, v. 59, no. 34

    2020  

    Abstract: This paper presents a new optimization framework that reconciles deterministic and metaheuristic optimization in order to solve nonconvex models. In this way, it is possible to solve the convex part in a software specialized in deterministic optimization ...

    Abstract This paper presents a new optimization framework that reconciles deterministic and metaheuristic optimization in order to solve nonconvex models. In this way, it is possible to solve the convex part in a software specialized in deterministic optimization and the nonconvex part using metaheuristic tools. The chosen software for the deterministic optimization part was general algebraic modeling system (GAMS), and the metaheuristic optimization algorithm is the improved multiobjective differential evolution (I-MODE) coded in visual basic for applications (VBA). Likewise, a linking strategy is proposed through VBA code to execute the GAMS solver. The new solution strategy consists in manipulating the data that serve as parameters in the problem to be solved in the GAMS platform and evaluating the performance of the optimal values of the objective functions in the I-MODE algorithm with updated values for the involved parameters. The proposed methodology is applied to the hydraulic fracturing (HF) process to obtain shale gas. The problem related to HF process corresponds to the use of fresh water necessary for the extraction of shale gas, as well as the type of technology that can be used in the treatment of flowback water. The mathematical model that optimizes the return water management problem is solved using deterministic optimization, while the scheduling is fixed using evolutionary algorithms of metaheuristic optimization strategies. The obtained results offer attractive alternatives for the specified objective functions in an acceptable computation time.
    Keywords algorithms ; computer software ; freshwater ; hybrids ; mathematical models ; process design ; shale gas ; water management
    Language English
    Dates of publication 2020-0731
    Size p. 15298-15308.
    Publishing place American Chemical Society
    Document type Article
    Note NAL-AP-2-clean
    ZDB-ID 1484436-9
    ISSN 1520-5045 ; 0888-5885
    ISSN (online) 1520-5045
    ISSN 0888-5885
    DOI 10.1021/acs.iecr.0c02867
    Database NAL-Catalogue (AGRICOLA)

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  10. Article ; Online: Periaqueductal gray matter echogenicity as a marker of migraine chronification: a case control study.

    Vilas, Dolores / Rubio, Sara / Gea, Mireia / Rios, Jose / Ispierto, Lourdes / Hernández-Pérez, María / Paré, Martí / Millán, Mònica / Dorado, Laura

    The journal of headache and pain

    2023  Volume 24, Issue 1, Page(s) 41

    Abstract: Background: Migraine is one of the most prevalent and disabling medical diseases in the world. The periaqueductal gray matter and the red nucleus play an important role in its pathogenesis. Our aim was to evaluate the echogenicity of the periaqueductal ... ...

    Abstract Background: Migraine is one of the most prevalent and disabling medical diseases in the world. The periaqueductal gray matter and the red nucleus play an important role in its pathogenesis. Our aim was to evaluate the echogenicity of the periaqueductal gray matter and the red nucleus in patients with migraine, by means of transcranial ultrasound.
    Methods: In this cross-sectional study, a group of patients with migraine (according to the International Classification of Headache Disorders) and a group of control subjects with comparable age-and-sex distribution were prospectively included. We evaluated the area and echogenicity of the periaqueductal gray matter and the red nucleus by means of transcranial ultrasound, both bedside and posteriorly analyzed with the medical image viewer Horos.
    Results: We included 115 subjects: 65 patients with migraine (39 of them with chronic migraine and 26 with episodic migraine), and 50 controls. Median disease duration in patients with chronic migraine was 29 (IQR: 19; 40) years, with a median of 18 (IQR: 14; 27) days of migraine per month. The area of the periaqueductal gray matter was larger in patients with chronic migraine compared to episodic migraine and controls (0.15[95%CI 0.12;0.22]cm
    Conclusion: Patients with chronic migraine showed a larger area of echogenicity of periaqueductal gray matter, a lower intensity of its echogenicity and a higher heterogenicity within this brainstem structure compared to patients with episodic migraine and controls. The echogenicity of the periaqueductal gray matter should be further investigated as a biomarker of migraine chronification.
    MeSH term(s) Humans ; Case-Control Studies ; Magnetic Resonance Imaging/methods ; Periaqueductal Gray/diagnostic imaging ; Cross-Sectional Studies ; Migraine Disorders/diagnostic imaging ; Migraine Disorders/pathology ; Gray Matter/diagnostic imaging ; Gray Matter/pathology
    Language English
    Publishing date 2023-04-17
    Publishing country England
    Document type Journal Article
    ZDB-ID 2036768-5
    ISSN 1129-2377 ; 1129-2369
    ISSN (online) 1129-2377
    ISSN 1129-2369
    DOI 10.1186/s10194-023-01576-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5464: Show issues Location:
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