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  1. Article ; Online: Screening of MnO

    Wang, Fan / Zheng, Yueying / Zhu, Huiwen / Wu, Tao

    Chemosphere

    2023  Volume 337, Page(s) 139239

    Abstract: In this study, Density Functional Theory (DFT) calculations and experimental methods were adopted to evaluate ... ...

    Abstract In this study, Density Functional Theory (DFT) calculations and experimental methods were adopted to evaluate MnO
    MeSH term(s) Cadmium ; Lead ; Oxides ; Adsorption ; Manganese Compounds ; Water
    Chemical Substances Cadmium (00BH33GNGH) ; Lead (2P299V784P) ; Oxides ; Manganese Compounds ; Water (059QF0KO0R)
    Language English
    Publishing date 2023-06-26
    Publishing country England
    Document type Journal Article
    ZDB-ID 120089-6
    ISSN 1879-1298 ; 0045-6535 ; 0366-7111
    ISSN (online) 1879-1298
    ISSN 0045-6535 ; 0366-7111
    DOI 10.1016/j.chemosphere.2023.139239
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  2. Article ; Online: Association of Interleukin-17A and Interleukin-17F Gene Polymorphisms with Atopic Dermatitis in Chinese Children.

    Shen, Chen / Li, Yunling / Huang, Jian / Li, Jing / Qi, Guoqiang / Zhu, Zhu / Zheng, Huiwen

    Genetic testing and molecular biomarkers

    2024  Volume 28, Issue 2, Page(s) 43–49

    Abstract: Background: ...

    Abstract Background:
    MeSH term(s) Child ; Humans ; Case-Control Studies ; China ; Dermatitis, Atopic/genetics ; Genetic Predisposition to Disease/genetics ; Genotype ; Interleukin-17/genetics ; Polymorphism, Single Nucleotide/genetics
    Chemical Substances Interleukin-17 ; IL17F protein, human ; IL17A protein, human
    Language English
    Publishing date 2024-02-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2486664-7
    ISSN 1945-0257 ; 1945-0265
    ISSN (online) 1945-0257
    ISSN 1945-0265
    DOI 10.1089/gtmb.2023.0379
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Risk Factors for Long COVID in Older Adults.

    Hu, Yunguang / Liu, Yifan / Zheng, Huiwen / Liu, Longding

    Biomedicines

    2023  Volume 11, Issue 11

    Abstract: As time has passed following the COVID-19 pandemic, individuals infected with SARS-CoV-2 have gradually exhibited a variety of symptoms associated with long COVID in the postacute phase of infection. Simultaneously, in many countries worldwide, the ... ...

    Abstract As time has passed following the COVID-19 pandemic, individuals infected with SARS-CoV-2 have gradually exhibited a variety of symptoms associated with long COVID in the postacute phase of infection. Simultaneously, in many countries worldwide, the process of population aging has been accelerating. Within this context, the elderly population has not only become susceptible and high-risk during the acute phase of COVID-19 but also has considerable risks when confronting long COVID. Elderly individuals possess specific immunological backgrounds, and during the process of aging, their immune systems can enter a state known as "immunosenescence". This further exacerbates "inflammaging" and the development of various comorbidities in elderly individuals, rendering them more susceptible to long COVID. Additionally, long COVID can inflict both physical and mental harm upon elderly people, thereby reducing their overall quality of life. Consequently, the impact of long COVID on elderly people should not be underestimated. This review seeks to summarize the infection characteristics and intrinsic factors of older adults during the COVID-19 pandemic, with a focus on the physical and mental impact of long COVID. Additionally, it aims to explore potential strategies to mitigate the risk of long COVID or other emerging infectious diseases among older adults in the future.
    Language English
    Publishing date 2023-11-08
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2720867-9
    ISSN 2227-9059
    ISSN 2227-9059
    DOI 10.3390/biomedicines11113002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Association between diet quality scores and risk of overweight and obesity in children and adolescents.

    Zheng, Xiaoyun / Wang, Hong / Wu, Huiwen

    BMC pediatrics

    2023  Volume 23, Issue 1, Page(s) 169

    Abstract: Background: This study examined the associations of diet quality assessed by Healthy Eating Index 2015 (HEI-2015), Alternative Healthy Eating Index 2010 (AHEI-2010), Mediterranean Diet (MedDiet) and overweight/obesity in children and adolescents.: ... ...

    Abstract Background: This study examined the associations of diet quality assessed by Healthy Eating Index 2015 (HEI-2015), Alternative Healthy Eating Index 2010 (AHEI-2010), Mediterranean Diet (MedDiet) and overweight/obesity in children and adolescents.
    Methods: This cross-sectional study used data of participants aged 2-19 years from National Health and Nutrition Examination Survey (NHANES) 2005-2018. The weighted logistic regression model was adopted to explore the association between diet quality scores and overweight, obesity in children and adolescents. Subgroup analysis was also performed based on sex.
    Results: A total of 9,724 participants were included in children group (2-11 years old), and 5,934 were adolescent group (12-19 years old). All participants were divided into based on the BMI-for-age: underweight and normal, overweight and obesity groups. After adjusting for age, race, poverty-income ratio, maternal smoking during pregnancy and total energy, HEI-2015 and MedDiet scores were related to the risk of overweight in children, and only MedDiet scores remained associated with a decreased risk of obesity in children. MedDiet scores were associated with a decreased risk of overweight, obesity in adolescents, respectively, after adjusting age, sex, race, poverty-income ratio, cotinine, total energy and physical activity. The similar results in male participants were also found.
    Conclusion: Higher MedDiet scores were associated with lower the risk of overweight and obesity, respectively, particularly for male children and adolescents. The higher HEI-2015 scores were also related to the risk of overweight in children.
    MeSH term(s) Child ; Female ; Pregnancy ; Adolescent ; Male ; Humans ; Child, Preschool ; Young Adult ; Adult ; Overweight/epidemiology ; Overweight/etiology ; Pediatric Obesity/epidemiology ; Pediatric Obesity/etiology ; Nutrition Surveys ; Cross-Sectional Studies ; Diet
    Language English
    Publishing date 2023-04-13
    Publishing country England
    Document type Journal Article
    ZDB-ID 2041342-7
    ISSN 1471-2431 ; 1471-2431
    ISSN (online) 1471-2431
    ISSN 1471-2431
    DOI 10.1186/s12887-023-03966-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Highly Stable Photo-Assisted Zinc-Ion Batteries via Regulated Photo-Induced Proton Transfer.

    Zha, Wenwen / Ruan, Qiushi / Ma, Long / Liu, Meng / Lin, Huiwen / Sun, Litao / Sun, ZhengMing / Tao, Li

    Angewandte Chemie (International ed. in English)

    2024  Volume 63, Issue 15, Page(s) e202400621

    Abstract: Photo-assisted ion batteries utilize light to boost capacity but face cycling instability due to complex charge/ion transfer under illumination. This study identified photo-induced proton transfer (photo-induced PT) as a significant process in photo-(dis) ...

    Abstract Photo-assisted ion batteries utilize light to boost capacity but face cycling instability due to complex charge/ion transfer under illumination. This study identified photo-induced proton transfer (photo-induced PT) as a significant process in photo-(dis)charging of widely-used V
    Language English
    Publishing date 2024-02-26
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2011836-3
    ISSN 1521-3773 ; 1433-7851
    ISSN (online) 1521-3773
    ISSN 1433-7851
    DOI 10.1002/anie.202400621
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Screening of MnO2 with desired facet and its behavior in highly selective adsorption of aqueous Pb (II): Theoretical and experimental studies

    Wang, Fan / Zheng, Yueying / Zhu, Huiwen / Wu, Tao

    Chemosphere. 2023 Oct., v. 337 p.139239-

    2023  

    Abstract: In this study, Density Functional Theory (DFT) calculations and experimental methods were adopted to evaluate MnO₂ with 5 different facets for their selective adsorption of Pb (II) from wastewater containing Cd (II), Cu (II), Pb (II), and Zn (II). The ... ...

    Abstract In this study, Density Functional Theory (DFT) calculations and experimental methods were adopted to evaluate MnO₂ with 5 different facets for their selective adsorption of Pb (II) from wastewater containing Cd (II), Cu (II), Pb (II), and Zn (II). The DFT calculations were performed to screen the selective adsorption capability of the facets and demonstrated that the MnO₂ (3 1 0) facet has an excellent performance in selective adsorption of Pb (II) among all facets. The validity of DFT calculations was verified by comparing with the experimental results. MnO₂ with different facets was prepared in a controlled manner and the characterizations confirmed that the lattice indices of the fabricated MnO₂ have the desired facets. Adsorption performance experiments illustrated a high adsorption capacity (320.0 mg/g) on the (3 1 0) facet MnO₂. The selectivity of adsorption of Pb (II) was 3–32 times greater than that of the other coexisting ions, i.e., Cd (II), Cu (II), and Zn (II)), which is consistent with results of the DFT calculations. Furthermore, results of DFT calculations on adsorption energy, charge density difference, and projected density of states (PDOS) showed that the adsorption of Pb (II) on the MnO₂ (3 1 0) facet is non-activated chemisorption. This study shows that it is feasible to use DFT calculations to quickly screen suitable adsorbents for environmental applications.
    Keywords adsorbents ; adsorption ; density functional theory ; energy ; manganese dioxide ; wastewater ; Screening ; facet ; Selective adsorption ; Heavy metal ; DFT Calculations
    Language English
    Dates of publication 2023-10
    Publishing place Elsevier Ltd
    Document type Article ; Online
    ZDB-ID 120089-6
    ISSN 1879-1298 ; 0045-6535 ; 0366-7111
    ISSN (online) 1879-1298
    ISSN 0045-6535 ; 0366-7111
    DOI 10.1016/j.chemosphere.2023.139239
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Cologne/Königswinter

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  7. Article ; Online: Measuring cell-to-cell expression variability in single-cell RNA-sequencing data: a comparative analysis and applications to B cell aging.

    Zheng, Huiwen / Vijg, Jan / Fard, Atefeh Taherian / Mar, Jessica Cara

    Genome biology

    2023  Volume 24, Issue 1, Page(s) 238

    Abstract: Background: Single-cell RNA-sequencing (scRNA-seq) technologies enable the capture of gene expression heterogeneity and consequently facilitate the study of cell-to-cell variability at the cell type level. Although different methods have been proposed ... ...

    Abstract Background: Single-cell RNA-sequencing (scRNA-seq) technologies enable the capture of gene expression heterogeneity and consequently facilitate the study of cell-to-cell variability at the cell type level. Although different methods have been proposed to quantify cell-to-cell variability, it is unclear what the optimal statistical approach is, especially in light of challenging data structures that are unique to scRNA-seq data like zero inflation.
    Results: We systematically evaluate the performance of 14 different variability metrics that are commonly applied to transcriptomic data for measuring cell-to-cell variability. Leveraging simulations and real datasets, we benchmark the metric performance based on data-specific features, sparsity and sequencing platform, biological properties, and the ability to recapitulate true levels of biological variability based on known gene sets. Next, we use scran, the metric with the strongest all-round performance, to investigate changes in cell-to-cell variability that occur during B cell differentiation and the aging processes. The analysis of primary cell types from hematopoietic stem cells (HSCs) and B lymphopoiesis reveals unique gene signatures with consistent patterns of variable and stable expression profiles during B cell differentiation which highlights the significance of these methods. Identifying differentially variable genes between young and old cells elucidates the regulatory changes that may be overlooked by solely focusing on mean expression changes and we investigate this in the context of regulatory networks.
    Conclusions: We highlight the importance of capturing cell-to-cell gene expression variability in a complex biological process like differentiation and aging and emphasize the value of these findings at the level of individual cell types.
    MeSH term(s) Sequence Analysis, RNA/methods ; Single-Cell Analysis/methods ; Cellular Senescence ; RNA/genetics
    Chemical Substances RNA (63231-63-0)
    Language English
    Publishing date 2023-10-20
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2040529-7
    ISSN 1474-760X ; 1474-760X
    ISSN (online) 1474-760X
    ISSN 1474-760X
    DOI 10.1186/s13059-023-03036-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Controllable chiral inversion

    He, Huiwen / Zheng, Kai / Du, Junnan / Zheng, Hao / He, Jing / Ma, Meng / Shi, Yanqin / Chen, Si / Wang, Xu

    Chemical communications (Cambridge, England)

    2023  Volume 59, Issue 25, Page(s) 3759–3762

    Abstract: Herein, thioether bonds in the peripheral groups of chiral dendrimer that could activate the transformation ... ...

    Abstract Herein, thioether bonds in the peripheral groups of chiral dendrimer that could activate the transformation between
    Language English
    Publishing date 2023-03-23
    Publishing country England
    Document type Journal Article
    ZDB-ID 1472881-3
    ISSN 1364-548X ; 1359-7345 ; 0009-241X
    ISSN (online) 1364-548X
    ISSN 1359-7345 ; 0009-241X
    DOI 10.1039/d3cc00019b
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Protocol for optimized dissociation of human scalp tissue for hair follicle transcriptomics by scRNA-seq.

    Yuan, Zishuo / Chen, Junjie / Xu, Yanwen / Zhou, Zhentao / Cai, Pengfei / Wei, Xiaoyu / Zheng, Huiwen / Zhang, Jufang / Yuan, Yue / Liu, Chuanyu

    STAR protocols

    2024  Volume 5, Issue 1, Page(s) 102848

    Abstract: Single-cell RNA sequencing (scRNA-seq) is a powerful tool for studying transcriptomics. Here, we present an optimized protocol for dissociating human scalp tissue and acquiring high-quality single-cell suspension for scRNA-seq to study transcriptomics of ...

    Abstract Single-cell RNA sequencing (scRNA-seq) is a powerful tool for studying transcriptomics. Here, we present an optimized protocol for dissociating human scalp tissue and acquiring high-quality single-cell suspension for scRNA-seq to study transcriptomics of human hair follicles. We describe steps for human scalp tissue cleaning, subcutaneous fat removal, mechanical mincing, and enzymatic digestion. We then detail procedures for cleaning, resuspending, a cell viability assay, and library construction.
    MeSH term(s) Humans ; Hair Follicle ; Scalp ; Single-Cell Gene Expression Analysis ; Sequence Analysis, RNA/methods ; Gene Expression Profiling/methods
    Language English
    Publishing date 2024-02-05
    Publishing country United States
    Document type Journal Article
    ISSN 2666-1667
    ISSN (online) 2666-1667
    DOI 10.1016/j.xpro.2024.102848
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Metal-free β,γ-C(sp

    Li, Zheyao / Zhang, Huiwen / Zhao, Lin / Ma, Yueyue / Wu, Qiufang / Ren, Haosong / Lin, Zhongren / Zheng, Jun / Yu, Xinhong

    Chemical communications (Cambridge, England)

    2024  Volume 60, Issue 26, Page(s) 3579–3582

    Abstract: A DMP-initiated metal-free effective β,γ-asymmetric spirocyclopropanation of propanols strategy using oxidative iminium activation is described. This process has been realized by a synergistic amine-catalyzed one-pot cascade oxidation-Michael addition ... ...

    Abstract A DMP-initiated metal-free effective β,γ-asymmetric spirocyclopropanation of propanols strategy using oxidative iminium activation is described. This process has been realized by a synergistic amine-catalyzed one-pot cascade oxidation-Michael addition cyclopropanation for "one-pot" access to various spirocyclopropyl propionaldehydes/propanols from diverse 3-arylpropanols and α-brominated active methylene compounds under mild conditions and with high enantioselectivity (ee up to >99%).
    Language English
    Publishing date 2024-03-26
    Publishing country England
    Document type Journal Article
    ZDB-ID 1472881-3
    ISSN 1364-548X ; 1359-7345 ; 0009-241X
    ISSN (online) 1364-548X
    ISSN 1359-7345 ; 0009-241X
    DOI 10.1039/d4cc00116h
    Database MEDical Literature Analysis and Retrieval System OnLINE

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