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  1. Article ; Online: Female fertility preservation in the pediatric and adolescent cancer patient population.

    Algarroba, Gabriela N / Sanfilippo, Joseph S / Valli-Pulaski, Hanna

    Best practice & research. Clinical obstetrics & gynaecology

    2017  Volume 48, Page(s) 147–157

    Abstract: The 5-year survival rate for childhood cancer is over 80%, thereby increasing the number of young women facing infertility in the future because of the gonadotoxic effects of chemotherapy and radiation. The gonadotoxic effects of childhood cancer ... ...

    Abstract The 5-year survival rate for childhood cancer is over 80%, thereby increasing the number of young women facing infertility in the future because of the gonadotoxic effects of chemotherapy and radiation. The gonadotoxic effects of childhood cancer treatment vary by the radiation regimen and the chemotherapeutic drugs utilized. Although the American Society of Clinical Oncology guidelines recommend fertility preservation for all patients, there are several barriers and ethical considerations to fertility preservation in the pediatric and adolescent female population. Additionally, the fertility preservation methods for pre- and postpubertal females differ, with only experimental methods available for prepubertal females. We will review the risk of chemotherapy and radiation on female fertility, the approach to fertility preservation in the pediatric and adolescent female population, methods of fertility preservation for both pre- and postpubertal females, barriers to fertility preservation, cost, and psychological and ethical considerations.
    MeSH term(s) Adolescent ; Age Factors ; Antineoplastic Agents/adverse effects ; Child ; Female ; Fertility Preservation/ethics ; Fertility Preservation/methods ; Humans ; Infertility/etiology ; Neoplasms/therapy ; Puberty ; Radiotherapy/adverse effects
    Chemical Substances Antineoplastic Agents
    Language English
    Publishing date 2017-10-26
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 2050090-7
    ISSN 1532-1932 ; 1521-6934
    ISSN (online) 1532-1932
    ISSN 1521-6934
    DOI 10.1016/j.bpobgyn.2017.10.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Reply.

    Algarroba, Gabriela N / Rekawek, Patricia / Vahanian, Sevan A / Khullar, Poonam / Palaia, Thomas / Peltier, Morgan R / Chavez, Martin R / Vintzileos, Anthony M

    American journal of obstetrics and gynecology

    2020  Volume 223, Issue 5, Page(s) 786–788

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus ; Coronavirus Infections ; Female ; Humans ; Microscopy, Electron ; Pandemics ; Placenta ; Pneumonia, Viral ; Pregnancy ; Pregnancy Complications, Infectious ; SARS-CoV-2 ; Severe Acute Respiratory Syndrome
    Keywords covid19
    Language English
    Publishing date 2020-06-09
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 80016-8
    ISSN 1097-6868 ; 0002-9378
    ISSN (online) 1097-6868
    ISSN 0002-9378
    DOI 10.1016/j.ajog.2020.06.017
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Visualization of severe acute respiratory syndrome coronavirus 2 invading the human placenta using electron microscopy.

    Algarroba, Gabriela N / Rekawek, Patricia / Vahanian, Sevan A / Khullar, Poonam / Palaia, Thomas / Peltier, Morgan R / Chavez, Martin R / Vintzileos, Anthony M

    American journal of obstetrics and gynecology

    2020  Volume 223, Issue 2, Page(s) 275–278

    MeSH term(s) Adult ; Betacoronavirus/isolation & purification ; COVID-19 ; Coronavirus Infections/transmission ; Coronavirus Infections/virology ; Female ; Humans ; Microscopy, Electron, Transmission/methods ; Pandemics ; Placenta/virology ; Pneumonia, Viral/transmission ; Pneumonia, Viral/virology ; Pregnancy ; Pregnancy Complications, Infectious/virology ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-05-13
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 80016-8
    ISSN 1097-6868 ; 0002-9378
    ISSN (online) 1097-6868
    ISSN 0002-9378
    DOI 10.1016/j.ajog.2020.05.023
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Confirmatory evidence of the visualization of severe acute respiratory syndrome coronavirus 2 invading the human placenta using electron microscopy.

    Algarroba, Gabriela N / Hanna, Nazeeh N / Rekawek, Patricia / Vahanian, Sevan A / Khullar, Poonam / Palaia, Thomas / Peltier, Morgan R / Chavez, Martin R / Vintzileos, Anthony M

    American journal of obstetrics and gynecology

    2020  Volume 223, Issue 6, Page(s) 953–954

    MeSH term(s) COVID-19 ; Female ; Humans ; Microscopy, Electron ; Pandemics ; Placenta ; Pregnancy ; Pregnancy Complications, Infectious ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-08-28
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 80016-8
    ISSN 1097-6868 ; 0002-9378
    ISSN (online) 1097-6868
    ISSN 0002-9378
    DOI 10.1016/j.ajog.2020.08.106
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  5. Article: Visualization of severe acute respiratory syndrome coronavirus 2 invading the human placenta using electron microscopy

    Algarroba, Gabriela N / Rekawek, Patricia / Vahanian, Sevan A / Khullar, Poonam / Palaia, Thomas / Peltier, Morgan R / Chavez, Martin R / Vintzileos, Anthony M

    Am J Obstet Gynecol

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #260010
    Database COVID19

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  6. Article: Confirmatory evidence of the visualization of severe acute respiratory syndrome coronavirus 2 invading the human placenta using electron microscopy

    Algarroba, Gabriela N / Hanna, Nazeeh N / Rekawek, Patricia / Vahanian, Sevan A / Khullar, Poonam / Palaia, Thomas / Peltier, Morgan R / Chavez, Martin R / Vintzileos, Anthony M

    Am. j. obstet. gynecol

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #734005
    Database COVID19

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  7. Article ; Online: A cluster-randomized trial of a college health center-based alcohol and sexual violence intervention (GIFTSS): Design, rationale, and baseline sample.

    Abebe, Kaleab Z / Jones, Kelley A / Rofey, Dana / McCauley, Heather L / Clark, Duncan B / Dick, Rebecca / Gmelin, Theresa / Talis, Janine / Anderson, Jocelyn / Chugani, Carla / Algarroba, Gabriela / Antonio, Ashley / Bee, Courtney / Edwards, Clare / Lethihet, Nadia / Macak, Justin / Paley, Joshua / Torres, Irving / Van Dusen, Courtney /
    Miller, Elizabeth

    Contemporary clinical trials

    2017  Volume 65, Page(s) 130–143

    Abstract: Introduction: Sexual violence (SV) on college campuses is common, especially alcohol-related SV. This is a 2-arm cluster randomized controlled trial to test a brief intervention to reduce risk for alcohol-related sexual violence (SV) among students ... ...

    Abstract Introduction: Sexual violence (SV) on college campuses is common, especially alcohol-related SV. This is a 2-arm cluster randomized controlled trial to test a brief intervention to reduce risk for alcohol-related sexual violence (SV) among students receiving care from college health centers (CHCs). Intervention CHC staff are trained to deliver universal SV education to all students seeking care, to facilitate patient and provider comfort in discussing SV and related abusive experiences (including the role of alcohol). Control sites provide participants with information about drinking responsibly.
    Methods: Across 28 participating campuses (12 randomized to intervention and 16 to control), 2292 students seeking care at CHCs complete surveys prior to their appointment (baseline), immediately after (exit), 4months later (T2) and one year later (T3). The primary outcome is change in recognition of SV and sexual risk. Among those reporting SV exposure at baseline, changes in SV victimization, disclosure, and use of SV services are additional outcomes. Intervention effects will be assessed using generalized linear mixed models that account for clustering of repeated observations both within CHCs and within students.
    Results: Slightly more than half of the participating colleges have undergraduate enrollment of ≥3000 students; two-thirds are public and almost half are urban. Among participants there were relatively more Asian (10 v 1%) and Black/African American (13 v 7%) and fewer White (58 v 74%) participants in the intervention compared to control.
    Conclusions: This study will offer the first formal assessment for SV prevention in the CHC setting. Clinical Trials #: NCT02355470.
    MeSH term(s) Adolescent ; Alcohol Drinking/prevention & control ; Counseling/methods ; Female ; Harm Reduction ; Health Education/organization & administration ; Health Knowledge, Attitudes, Practice ; Humans ; Male ; Motivational Interviewing ; Referral and Consultation ; Self Efficacy ; Sex Offenses/prevention & control ; Student Health Services/methods ; Student Health Services/organization & administration ; Universities ; Young Adult ; Randomized Controlled Trials as Topic
    Language English
    Publishing date 2017-12-26
    Publishing country United States
    Document type Clinical Trial Protocol ; Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 2182176-8
    ISSN 1559-2030 ; 1551-7144
    ISSN (online) 1559-2030
    ISSN 1551-7144
    DOI 10.1016/j.cct.2017.12.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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