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  1. Article ; Online: Children of single-parent households are at a higher risk of obesity: A systematic review.

    Duriancik, David M / Goff, Courtney R

    Journal of child health care : for professionals working with children in the hospital and community

    2019  Volume 23, Issue 3, Page(s) 358–369

    Abstract: The goal of this systematic review was to evaluate whether children living in single-parent households have a higher risk of obesity. Of the 539 studies identified using keywords, a total of 10 original studies met the inclusion criteria for this review. ...

    Abstract The goal of this systematic review was to evaluate whether children living in single-parent households have a higher risk of obesity. Of the 539 studies identified using keywords, a total of 10 original studies met the inclusion criteria for this review. The outcome measures included objective assessment of adiposity (weight or body mass index (BMI)), dietary consumption, physical activity, and/or obesogenic behaviors (bedroom television, elevated television viewing time, insufficient physical activity, and infrequent family meals). Overall, the studies found higher BMIs and obesogenic behaviors in children of single-parent households. Characteristics identified with this association is comprised of being most prevalent among girls and Black children. Possible explanations for this association include single-parent households having higher time demands due to the lack of shared household responsibilities. Subsequently, a reduction of homemade meals, shared family meals, and physical activity can occur. Also, lower incomes and higher instability related to living transitions may be other possible challenges experienced in single-parent households. Based on the limited number of studies found, further research of the obesity risk in children from single-parent families is recommended. The findings can help provide clinicians and public health programs with a better understanding of how to effectively target family-based interventions for this population.
    MeSH term(s) Body Mass Index ; Child ; Diet ; Exercise ; Family Characteristics ; Family Therapy ; Humans ; Obesity/ethnology ; Obesity/psychology ; Risk Factors ; Screen Time ; Single-Parent Family/ethnology
    Language English
    Publishing date 2019-05-26
    Publishing country England
    Document type Journal Article ; Systematic Review
    ZDB-ID 2299167-0
    ISSN 1741-2889 ; 1367-4935
    ISSN (online) 1741-2889
    ISSN 1367-4935
    DOI 10.1177/1367493519852463
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Management of Small Intestinal Bacterial Overgrowth in Adult Patients.

    Rasmussen, Jamie / Duriancik, David M

    Gastroenterology nursing : the official journal of the Society of Gastroenterology Nurses and Associates

    2019  Volume 42, Issue 3, Page(s) 269–276

    Abstract: The human gastrointestinal tract is a complex system of digestive pathways aided by mechanical processes, enzymes, transport molecules, and colonic bacteria. Occasionally, these bacterial components transplant to atypical locations due to various ... ...

    Abstract The human gastrointestinal tract is a complex system of digestive pathways aided by mechanical processes, enzymes, transport molecules, and colonic bacteria. Occasionally, these bacterial components transplant to atypical locations due to various gastrointestinal imbalances or anatomical structural issues. This may lead to bacterial overgrowth of the small intestine, where minimal or no bacteria are normally found. Symptoms of small intestinal bacterial overgrowth may mimic those of various functional gastrointestinal diseases. Small intestinal bacterial overgrowth is typically diagnosed through hydrogen breath tests or jejunal aspirate culture. Current recommendations indicate antibiotics as the first-line treatment to eradicate or modify the bacterial overgrowth to a more favorable state. Nutritional support is also indicated to correct deficiencies and aid in symptom alleviation. As small intestinal bacterial overgrowth is common in other conditions, much of the research for this area is based on findings in codisease states rather than independent disease research. To provide accurate recommendations for small intestinal bacterial overgrowth, more targeted research is needed.
    MeSH term(s) Adult ; Blind Loop Syndrome/diagnosis ; Blind Loop Syndrome/etiology ; Blind Loop Syndrome/therapy ; Female ; Humans ; Intestine, Small ; Male
    Language English
    Publishing date 2019-05-30
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1109536-2
    ISSN 1538-9766 ; 1042-895X
    ISSN (online) 1538-9766
    ISSN 1042-895X
    DOI 10.1097/SGA.0000000000000369
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Impact of Carbohydrate Restriction on Healthy Adolescent Development.

    Richmond, Hannah M / Duriancik, David M

    Pediatric endocrinology reviews : PER

    2017  Volume 15, Issue 1, Page(s) 26–32

    Abstract: Carbohydrate-restricted diets are known for their impact on weight loss; however, research is still required to determine if low-carbohydrate diets are safe for adolescents. Carbohydrates directly stimulate an insulin response, and studies have recently ... ...

    Abstract Carbohydrate-restricted diets are known for their impact on weight loss; however, research is still required to determine if low-carbohydrate diets are safe for adolescents. Carbohydrates directly stimulate an insulin response, and studies have recently shown that insulin and binding to respective insulin receptors (IRs) are critical in Kisspeptin (Kiss1) neuronal development. These neurons directly stimulate gonadotropin-releasing hormone, which activates the pituitary-gonadal axis during puberty. This information suggests that carbohydrate restriction may delay pubertal development in adolescents due to the impact on insulin and Kiss1 transcription. Studies have observed disturbed insulin metabolism in Type I Diabetics leading to delayed puberty, along with overfeeding stimulating early pubertal onset. Additionally, recent clinical trials bred female mice with IR deletions on Kiss1 neurons and observed delayed vaginal opening and estrus. Current animal research suggests low carbohydrate intake may delay pubertal onset, however additional research is required to determine outcome in human subjects.
    Language English
    Publishing date 2017-09
    Publishing country Israel
    Document type Journal Article
    ZDB-ID 2434390-0
    ISSN 1565-4753
    ISSN 1565-4753
    DOI 10.17458/per.vol15.2017.rd.impactcarbohydraterestriction
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Energy restriction impairs dendritic cell development in C57BL/6J mice.

    Duriancik, David M / Gardner, Elizabeth M

    Mechanisms of ageing and development

    2016  Volume 154, Page(s) 9–19

    Abstract: Dendritic cells (DC) are antigen-presenting cells known for stimulating naïve T lymphocytes. The sequential stages of DC development from common myeloid progenitors have been elucidated in murine bone marrow. Energy-restriction (ER) is a pro-longevity ... ...

    Abstract Dendritic cells (DC) are antigen-presenting cells known for stimulating naïve T lymphocytes. The sequential stages of DC development from common myeloid progenitors have been elucidated in murine bone marrow. Energy-restriction (ER) is a pro-longevity dietary intervention with mixed immunological outcomes. The objective of this study was to examine the development of DC in adult C57Bl6J mice fed a 40% ER diet. We observed increased myeloid progenitors, but decreased common DC progenitors, precursor conventional DC and plasmacytoid DC. Furthermore, we observed increased macrophages and cells expressing CD169 in the bone marrow of ER mice. There was no significant difference in DC subsets from unfractionated ER and ad libitum-fed murine bone marrow samples cultured in GM-CSF-supplemented media or Flt3L-supplemented media. Examining rates of proliferation with 6h BrdU incorporation and Ki-67 staining showed these DC progenitor populations have different proliferation rates in ER compared with AL mice. We show here, for the first time, ER results in altered myelopoiesis resulting in reduced DC development but enhanced monocyte/macrophage development in steady-state C57Bl6J mice. In conclusion, these data may partially explain prior observations of impaired early innate immune responses to primary infection such as influenza in ER mice.
    MeSH term(s) Animals ; Bone Marrow/immunology ; Bone Marrow/pathology ; Caloric Restriction/adverse effects ; Dendritic Cells/immunology ; Dendritic Cells/pathology ; Immunity, Innate ; Mice ; Myeloid Progenitor Cells/immunology ; Myeloid Progenitor Cells/pathology ; Orthomyxoviridae Infections/immunology ; Orthomyxoviridae Infections/pathology ; Plasma Cells/immunology ; Plasma Cells/pathology ; Sialic Acid Binding Ig-like Lectin 1/immunology
    Chemical Substances Sialic Acid Binding Ig-like Lectin 1 ; Siglec1 protein, mouse
    Language English
    Publishing date 2016-03
    Publishing country Ireland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 183915-9
    ISSN 1872-6216 ; 0047-6374
    ISSN (online) 1872-6216
    ISSN 0047-6374
    DOI 10.1016/j.mad.2016.02.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Mistaken identity: purified basophils likely contaminated with dendritic cells.

    Duriancik, David M / Hoag, Kathleen A

    Cytometry. Part A : the journal of the International Society for Analytical Cytology

    2014  Volume 85, Issue 7, Page(s) 570–572

    MeSH term(s) Animals ; Antigen Presentation/immunology ; Antigens, CD/analysis ; Basophils/cytology ; Basophils/immunology ; Dendritic Cells/cytology ; Dendritic Cells/immunology ; Flow Cytometry ; Histocompatibility Antigens Class II/biosynthesis ; Histocompatibility Antigens Class II/genetics ; Humans ; Mast Cells/cytology ; Mice ; Receptors, Pattern Recognition/biosynthesis ; Receptors, Pattern Recognition/immunology ; Th2 Cells/immunology
    Chemical Substances Antigens, CD ; Histocompatibility Antigens Class II ; Receptors, Pattern Recognition
    Language English
    Publishing date 2014-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2099868-5
    ISSN 1552-4930 ; 0196-4763 ; 1552-4922
    ISSN (online) 1552-4930
    ISSN 0196-4763 ; 1552-4922
    DOI 10.1002/cyto.a.22476
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Age, calorie restriction, and age of calorie restriction onset reduce maturation of natural killer cells in C57Bl/6 mice.

    Duriancik, David M / Tippett, Jared J / Morris, Jaslyn L / Roman, Brooke E / Gardner, Elizabeth M

    Nutrition research (New York, N.Y.)

    2018  Volume 55, Page(s) 81–93

    Abstract: Calorie restriction (CR), also known as energy restriction, has been shown to have a deleterious impact on both adult and aged mouse survival during influenza virus infection. Natural killer (NK) cell phenotypic differences contribute to increased ... ...

    Abstract Calorie restriction (CR), also known as energy restriction, has been shown to have a deleterious impact on both adult and aged mouse survival during influenza virus infection. Natural killer (NK) cell phenotypic differences contribute to increased susceptibility of adult CR mice. We hypothesized NK cell phenotype from adult and aged C57Bl/6 mice fed NIH-31 diet ad libitum (AL) would be different from NK cell phenotype from adult and aged mice fed NIH-31/NIA fortified diet at 40% CR. We hypothesized NK cell phenotype from mice consuming 40% CR initiated at 20 months of age would not be different from 40% CR initiated at 3 months of age. We initiated the 40% restriction either at the standard 12 weeks of age or at 78 weeks of age. NK cells were isolated and quantified from various tissues using flow cytometry. Aged CR mice had significantly reduced levels of terminally mature (CD27
    MeSH term(s) Age Factors ; Aging/physiology ; Animals ; CD11 Antigens/metabolism ; Caloric Restriction ; Energy Intake ; Flow Cytometry ; Interleukin-7 Receptor alpha Subunit/metabolism ; Killer Cells, Natural/metabolism ; Lung/metabolism ; Male ; Mice, Inbred C57BL ; Spleen/metabolism ; Tumor Necrosis Factor Receptor Superfamily, Member 7/metabolism
    Chemical Substances CD11 Antigens ; Interleukin-7 Receptor alpha Subunit ; Tumor Necrosis Factor Receptor Superfamily, Member 7
    Language English
    Publishing date 2018-04-21
    Publishing country United States
    Document type Comparative Study ; Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 582432-1
    ISSN 1879-0739 ; 0271-5317
    ISSN (online) 1879-0739
    ISSN 0271-5317
    DOI 10.1016/j.nutres.2018.04.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Vitamin A deficiency alters splenic dendritic cell subsets and increases CD8(+)Gr-1(+) memory T lymphocytes in C57BL/6J mice.

    Duriancik, David M / Hoag, Kathleen A

    Cellular immunology

    2010  Volume 265, Issue 2, Page(s) 156–163

    Abstract: Vitamin A-deficient populations have impaired T cell-dependent antibody responses. Dendritic cells (DCs) are the most proficient antigen-presenting cells to naïve T cells. In the mouse, CD11b(+) myeloid DCs stimulate T helper (Th) 2 antibody immune ... ...

    Abstract Vitamin A-deficient populations have impaired T cell-dependent antibody responses. Dendritic cells (DCs) are the most proficient antigen-presenting cells to naïve T cells. In the mouse, CD11b(+) myeloid DCs stimulate T helper (Th) 2 antibody immune responses, while CD8α(+) lymphoid DCs stimulate Th1 cell-mediated immune responses. Therefore, we hypothesized that vitamin A-deficient animals would have decreased numbers of myeloid DCs and unaffected numbers of lymphoid DCs. We performed dietary depletion of vitamin A in C57BL/6J male and female mice and used multicolor flow cytometry to quantify immune cell populations of the spleen, with particular focus on DC subpopulations. We show that vitamin A-depleted animals have increased polymorphonuclear neutrophils, lymphoid DCs, and memory CD8(+) T cells and decreased CD4(+) T lymphocytes. Therefore, vitamin A deficiency alters splenic DC subpopulations, which may contribute to skewed immune responses of vitamin A-deficient populations.
    MeSH term(s) Animals ; CD11b Antigen ; CD4-Positive T-Lymphocytes/immunology ; CD4-Positive T-Lymphocytes/pathology ; CD8-Positive T-Lymphocytes/immunology ; CD8-Positive T-Lymphocytes/pathology ; Dendritic Cells/immunology ; Dendritic Cells/pathology ; Female ; Flow Cytometry ; Immunologic Memory ; Immunophenotyping ; Lymphocyte Activation ; Male ; Mice ; Mice, Inbred C57BL ; Neutrophils/immunology ; Neutrophils/pathology ; Spleen/immunology ; Spleen/pathology ; Vitamin A Deficiency/immunology ; Vitamin A Deficiency/pathology
    Chemical Substances CD11b Antigen
    Language English
    Publishing date 2010-08-24
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 80094-6
    ISSN 1090-2163 ; 0008-8749
    ISSN (online) 1090-2163
    ISSN 0008-8749
    DOI 10.1016/j.cellimm.2010.08.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: High levels of fish oil enhance neutrophil development and activation and influence colon mucus barrier function in a genetically susceptible mouse model.

    Duriancik, David M / Comstock, Sarah S / Langohr, Ingeborg M / Fenton, Jenifer I

    The Journal of nutritional biochemistry

    2015  Volume 26, Issue 11, Page(s) 1261–1272

    Abstract: Dietary fatty acids influence immunologic homeostasis, but their effect on initiation of colitis, an immune-mediated disease, is not well established. Previously, our laboratory demonstrated that high doses of dietary fish oil (FO) increased colon ... ...

    Abstract Dietary fatty acids influence immunologic homeostasis, but their effect on initiation of colitis, an immune-mediated disease, is not well established. Previously, our laboratory demonstrated that high doses of dietary fish oil (FO) increased colon inflammation and dysplasia in a model of infection-induced colitis. In the current study, we assessed the effects of high-dose dietary FO, 6% by weight, on colon inflammation, neutrophil recruitment and function, and mucus layer integrity in a genetically susceptible, colitis-prone mouse model in the absence of infection. FO-fed SMAD3(-/-) mice had increased colon inflammation evidenced by increased numbers of systemic and local neutrophils and increased neutrophil chemoattractant and inflammatory cytokine gene expression in the colon. Mucus layer thickness in the cecum and goblet cell numbers in the cecum and colon in FO-fed mice were reduced compared to control. FO consumption affected colitis in male and female mice differently. Compared to female control mice, neutrophils from FO-fed female mice had reduced reactive oxygen species (ROS) upon ex vivo stimulation with phorbol myristate acetate while FO-fed male mice produced increased ROS compared to control-fed male mice. In summary, dietary FO impaired mucus layer integrity and was associated with colon inflammation characterized by increased neutrophil numbers and altered neutrophil function. High-dose FO may have detrimental effects in populations genetically susceptible for inflammatory bowel disease and these effects may differ between males and females.
    MeSH term(s) Animals ; Bone Marrow Cells/drug effects ; Colitis/chemically induced ; Colitis/pathology ; Colon/drug effects ; Female ; Fish Oils/adverse effects ; Fish Oils/pharmacology ; Gene Expression Regulation/drug effects ; Intestinal Mucosa/drug effects ; Intestinal Mucosa/pathology ; Male ; Mice, Mutant Strains ; Neutrophils/drug effects ; Smad3 Protein/genetics
    Chemical Substances Fish Oils ; Smad3 Protein ; Smad3 protein, mouse
    Language English
    Publishing date 2015-11
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1014929-6
    ISSN 1873-4847 ; 0955-2863
    ISSN (online) 1873-4847
    ISSN 0955-2863
    DOI 10.1016/j.jnutbio.2015.06.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Age, calorie restriction, and age of calorie restriction onset reduce maturation of natural killer cells in C57Bl/6 mice

    Duriancik, David M / Tippett, Jared J / Morris, Jaslyn L / Roman, Brooke E / Gardner, Elizabeth M

    Nutrition research. 2018 July, v. 55

    2018  

    Abstract: Calorie restriction (CR), also known as energy restriction, has been shown to have a deleterious impact on both adult and aged mouse survival during influenza virus infection. Natural killer (NK) cell phenotypic differences contribute to increased ... ...

    Abstract Calorie restriction (CR), also known as energy restriction, has been shown to have a deleterious impact on both adult and aged mouse survival during influenza virus infection. Natural killer (NK) cell phenotypic differences contribute to increased susceptibility of adult CR mice. We hypothesized NK cell phenotype from adult and aged C57Bl/6 mice fed NIH-31 diet ad libitum (AL) would be different from NK cell phenotype from adult and aged mice fed NIH-31/NIA fortified diet at 40% CR. We hypothesized NK cell phenotype from mice consuming 40% CR initiated at 20 months of age would not be different from 40% CR initiated at 3 months of age. We initiated the 40% restriction either at the standard 12 weeks of age or at 78 weeks of age. NK cells were isolated and quantified from various tissues using flow cytometry. Aged CR mice had significantly reduced levels of terminally mature (CD27−CD11b+) NK cells, increased expression of the immature marker CD127, and decreased expression of the mature marker DX5. Total number of NK cells among cells was significantly lower in the lung and spleen of old-onset aged CR mice compared to aged AL mice, while there was no significant difference between young-onset aged CR and aged AL mice. Old-onset aged CR mice had significantly less early mature (DX5+ and CD27+CD11b+) NK cells compared to young-onset aged CR and aged AL fed mice. Overall, we found that CR in aged mice is detrimental to maturation of NK cells, which is exacerbated when CR is initiated in old age.
    Keywords Orthomyxoviridae ; adults ; energy ; flow cytometry ; low calorie diet ; lungs ; mice ; natural killer cells ; phenotype ; spleen ; tissues
    Language English
    Dates of publication 2018-07
    Size p. 81-93.
    Publishing place Elsevier Inc.
    Document type Article
    ZDB-ID 582432-1
    ISSN 1879-0739 ; 0271-5317
    ISSN (online) 1879-0739
    ISSN 0271-5317
    DOI 10.1016/j.nutres.2018.04.009
    Database NAL-Catalogue (AGRICOLA)

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  10. Article ; Online: The identification and enumeration of dendritic cell populations from individual mouse spleen and Peyer's patches using flow cytometric analysis.

    Duriancik, David M / Hoag, Kathleen A

    Cytometry. Part A : the journal of the International Society for Analytical Cytology

    2009  Volume 75, Issue 11, Page(s) 951–959

    Abstract: Dendritic cell (DC) research currently involves pooling of tissues from multiple animals followed by enrichment techniques to obtain sufficient numbers of DCs for analysis. Enrichment techniques take advantage of DC adherence, buoyant density properties, ...

    Abstract Dendritic cell (DC) research currently involves pooling of tissues from multiple animals followed by enrichment techniques to obtain sufficient numbers of DCs for analysis. Enrichment techniques take advantage of DC adherence, buoyant density properties, and/or positive or negative selection of cell populations using monoclonal antibodies. However, enrichment techniques may significantly change the maturation and/or activation status of DCs or selectively eliminate one or more subpopulations of DCs. To overcome these drawbacks, we designed a multicolor flow cytometric technique for simultaneous analysis of DC populations from tissues of individual mice. The spleens and Peyer's patches were mechanically and enzymatically digested, then incubated with a panel of six monoclonal antibody-fluorochrome direct conjugate reagents. A BD(R) Biosciences LSR II flow cytometer and FCS Express(R) software were used to identify three subtypes of mature DCs (myeloid, lymphoid, and plasmacytoid), precursor DCs, polymorphonuclear neutrophils, B lymphocytes, and Gr-1(+)/CD8alpha(+) memory T lymphocytes in the spleen. Likewise, we also identified these DC subpopulations and B lymphocytes in the Peyer's patches. The three key parameters in analysis of the DC populations were bi-exponential plotting in data analysis, collection of a minimum of 50,000 total events, and accurate color compensation. This procedure to analyze DCs from individual mice can lead to further understanding of the role of DCs in many other model systems as well as better understanding of how dietary or physiological factors may affect in vivo DC homeostasis.
    MeSH term(s) Animals ; CD8 Antigens/biosynthesis ; Cell Separation/methods ; Dendritic Cells/cytology ; Female ; Flow Cytometry/methods ; Homeostasis ; Immunologic Memory ; Male ; Mice ; Mice, Inbred C57BL ; Peyer's Patches/cytology ; Receptors, Chemokine/biosynthesis ; Spleen/cytology ; T-Lymphocytes/cytology
    Chemical Substances CD8 Antigens ; Gr-1 protein, mouse ; Receptors, Chemokine
    Language English
    Publishing date 2009-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2099868-5
    ISSN 1552-4930 ; 0196-4763 ; 1552-4922
    ISSN (online) 1552-4930
    ISSN 0196-4763 ; 1552-4922
    DOI 10.1002/cyto.a.20794
    Database MEDical Literature Analysis and Retrieval System OnLINE

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