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  1. Article: COVID-19 and Vitamin D- a Systematic Review.

    Jordan, Taja / Siuka, Darko / Rotovnik, Nada Kozjek / Pfeifer, Marija

    Zdravstveno varstvo

    2022  Volume 61, Issue 2, Page(s) 124–132

    Abstract: Introduction: The COVID-19 pandemic has strongly affected global healthcare systems. Prior epidemiological studies on different infectious diseases have shown a strong correlation between serum vitamin D levels and the incidence of certain infectious ... ...

    Abstract Introduction: The COVID-19 pandemic has strongly affected global healthcare systems. Prior epidemiological studies on different infectious diseases have shown a strong correlation between serum vitamin D levels and the incidence of certain infectious diseases. Vitamin D has an important immunomodulatory effect on innate immunity and exhibits several other mechanisms in the pathogenesis of the cytokine storm, which is one of the main contributing factors to fatality in COVID-19 patients.
    Methods: A keyword search was conducted in the PubMed and Google Scholar research databases. The abstracts and/or full texts of selected papers were further evaluated. Articles that fulfilled the inclusion criteria were included in the systematic review.
    Results: The 28 studies summarized in this review provide observational findings that vitamin D levels are related to the incidence, severity, and mortality rate of COVID-19 infection. The literature does not suggest that COVID-19 could be eliminated with supplementation of vitamin D, but there are implications that vitamin D deficiency might increase the risk for COVID-19 infection and severity of the disease progression.
    Discussion: Current literature and several guidelines support the supplementation of vitamin D as a reasonable strategy for correcting and preventing vitamin D deficiency. The recommended dose for maintaining normal 25(OH)D levels by consensus is 1000 to 2000 IU vitamin D daily for at-risk teens and adults.
    Conclusion: Vitamin D supplementation might play an important role in protecting from acute respiratory infections like the SARS CoV2, and in high-risk individuals with COVID 19 from progressing to critical clinical condition and reducing mortality.
    Language English
    Publishing date 2022-03-21
    Publishing country Poland
    Document type Journal Article
    ISSN 0351-0026
    ISSN 0351-0026
    DOI 10.2478/sjph-2022-0017
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Performance of European and American Societies of Gastrointestinal Endoscopy Guidelines for Prediction of Choledocholithiasis in Patients with Acute Biliary Pancreatitis.

    Černe, Žan Peter / Sever, Nejc / Strniša, Luka / Plut, Samo / Drnovšek, Jan / Hanžel, Jurij / Siuka, Darko / Štabuc, Borut / Drobne, David

    Medicina (Kaunas, Lithuania)

    2023  Volume 59, Issue 12

    Abstract: Background and Objectives: ...

    Abstract Background and Objectives:
    MeSH term(s) Humans ; United States ; Choledocholithiasis/complications ; Choledocholithiasis/diagnosis ; Retrospective Studies ; Acute Disease ; Pancreatitis/complications ; Pancreatitis/diagnosis ; Endoscopy, Gastrointestinal/methods ; Bilirubin
    Chemical Substances Bilirubin (RFM9X3LJ49)
    Language English
    Publishing date 2023-12-15
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2188113-3
    ISSN 1648-9144 ; 1010-660X
    ISSN (online) 1648-9144
    ISSN 1010-660X
    DOI 10.3390/medicina59122176
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  3. Article ; Online: COVID-19 and vitamin D– a systematic review

    Jordan Taja / Siuka Darko / Rotovnik Nada Kozjek / Pfeifer Marija

    Slovenian Journal of Public Health, Vol 61, Iss 2, Pp 124-

    2022  Volume 132

    Abstract: The COVID-19 pandemic has strongly affected global healthcare systems. Prior epidemiological studies on different infectious diseases have shown a strong correlation between serum vitamin D levels and the incidence of certain infectious diseases. Vitamin ...

    Abstract The COVID-19 pandemic has strongly affected global healthcare systems. Prior epidemiological studies on different infectious diseases have shown a strong correlation between serum vitamin D levels and the incidence of certain infectious diseases. Vitamin D has an important immunomodulatory effect on innate immunity and exhibits several other mechanisms in the pathogenesis of the cytokine storm, which is one of the main contributing factors to fatality in COVID-19 patients.
    Keywords covid-19 ; vitamin d ; systematic reviews ; sistematični pregledi ; Public aspects of medicine ; RA1-1270
    Language English
    Publishing date 2022-03-01T00:00:00Z
    Publisher Sciendo
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Vitamin D Supplementation During the COVID-19 Pandemic.

    Siuka, Darko / Pfeifer, Marija / Pinter, Bojana

    Mayo Clinic proceedings

    2020  Volume 95, Issue 8, Page(s) 1804–1805

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections/epidemiology ; Coronavirus Infections/etiology ; Coronavirus Infections/prevention & control ; Dietary Supplements ; Global Health ; Humans ; Pandemics/prevention & control ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/etiology ; Pneumonia, Viral/prevention & control ; Risk Factors ; SARS-CoV-2 ; Vitamin D/therapeutic use ; Vitamin D Deficiency/complications ; Vitamin D Deficiency/drug therapy ; Vitamins/therapeutic use
    Chemical Substances Vitamins ; Vitamin D (1406-16-2)
    Keywords covid19
    Language English
    Publishing date 2020-06-06
    Publishing country England
    Document type Letter
    ZDB-ID 124027-4
    ISSN 1942-5546 ; 0025-6196
    ISSN (online) 1942-5546
    ISSN 0025-6196
    DOI 10.1016/j.mayocp.2020.05.036
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    Ua VI Zs.183: Show issues Location:
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  5. Article ; Online: Abbreviated

    Siuka, Darko / Kumer, Kristina / Stabuc, Borut / Stubljar, David / Drobne, David / Jansa, Rado

    Radiology and oncology

    2022  Volume 56, Issue 3, Page(s) 390–397

    Abstract: Background: 13: Subjects and methods: This cross-sectional observational study included 3 groups of subjects; healthy controls, patients with subtotal and patients with total gastrectomy. Demographic and clinical data of patients were collected. ... ...

    Abstract Background: 13
    Subjects and methods: This cross-sectional observational study included 3 groups of subjects; healthy controls, patients with subtotal and patients with total gastrectomy. Demographic and clinical data of patients were collected. Stool samples to determine faecal elastase (Fe-1) and chymotrypsin were collected and measured by ELISA. All subjects performed 5-hour
    Results: Overall, 65 participants were included into analysis, 22 having PEI (n = 11 after subtotal and n = 11 after total gastrectomy, both performed for gastric cancer).
    Conclusions: In this study abbreviated
    MeSH term(s) Breath Tests ; Cross-Sectional Studies ; Exocrine Pancreatic Insufficiency/diagnosis ; Exocrine Pancreatic Insufficiency/etiology ; Gastrectomy ; Humans ; Stomach Neoplasms/diagnosis ; Stomach Neoplasms/surgery ; Triglycerides
    Chemical Substances Triglycerides
    Language English
    Publishing date 2022-08-14
    Publishing country Poland
    Document type Journal Article ; Observational Study
    ZDB-ID 1128829-2
    ISSN 1581-3207 ; 0485-893X ; 1318-2099
    ISSN (online) 1581-3207
    ISSN 0485-893X ; 1318-2099
    DOI 10.2478/raon-2022-0034
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.B 2674: Show issues Location:
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  6. Article ; Online: Abbreviated 13C-mixed triglyceride breath test for detection of pancreatic exocrine insufficiency performs equally as standard 5-hour test in patients after gastrectomy performed for gastric cancer

    Siuka Darko / Kumer Kristina / Stabuc Borut / Stubljar David / Drobne David / Jansa Rado

    Radiology and Oncology, Vol 56, Iss 3, Pp 390-

    2022  Volume 397

    Abstract: 13C-mixed triglyceride breath test (13C-MTGT) is a non-invasive test for the detection of moderate and severe pancreatic exocrine insufficiency (PEI), but it requires prolonged breath sampling. The aim of this study was to determine the diagnostic power ... ...

    Abstract 13C-mixed triglyceride breath test (13C-MTGT) is a non-invasive test for the detection of moderate and severe pancreatic exocrine insufficiency (PEI), but it requires prolonged breath sampling. The aim of this study was to determine the diagnostic power of abbreviated 13C-MTGT in detecting PEI in patients after subtotal and total gastrectomy performed due to gastric cancer.
    Keywords abbreviated 13c-mixed triglyceride breath test ; pancreatic exocrine insufficiency ; gastrectomy ; faecal elastase ; gastric cancer ; Medical physics. Medical radiology. Nuclear medicine ; R895-920
    Language English
    Publishing date 2022-08-01T00:00:00Z
    Publisher Sciendo
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Vitamin D supplementation in the COVID-19 pandemic

    Siuka, Darko / Pfeifer, Marija / Pinter, Bojana

    Mayo Clin Proc

    Keywords covid19
    Publisher Elsevier; PMC; WHO
    Document type Article ; Online
    Note WHO #Covidence: #548609
    DOI 10.1016/j.mayocp.2020.05.036
    Database COVID19

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  9. Article ; Online: Vitamin D Supplementation During the COVID-19 Pandemic

    Siuka, Darko / Pfeifer, Marija / Pinter, Bojana

    Mayo Clinic Proceedings

    2020  Volume 95, Issue 8, Page(s) 1804–1805

    Keywords General Medicine ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ZDB-ID 124027-4
    ISSN 1942-5546 ; 0025-6196
    ISSN (online) 1942-5546
    ISSN 0025-6196
    DOI 10.1016/j.mayocp.2020.05.036
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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    In stock of ZB MED Cologne/Königswinter

    Ua VI Zs.183: Show issues Location:
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  10. Article ; Online: Performance of European and American Societies of Gastrointestinal Endoscopy Guidelines for Prediction of Choledocholithiasis in Patients with Acute Biliary Pancreatitis

    Žan Peter Černe / Nejc Sever / Luka Strniša / Samo Plut / Jan Drnovšek / Jurij Hanžel / Darko Siuka / Borut Štabuc / David Drobne

    Medicina, Vol 59, Iss 12, p

    2023  Volume 2176

    Abstract: Background and Objectives: Up to one-third of patients with acute biliary pancreatitis also present with choledocholithiasis. Guidelines from the European Society of Gastrointestinal Endoscopy (ESGE) and the American Society for Gastrointestinal ... ...

    Abstract Background and Objectives: Up to one-third of patients with acute biliary pancreatitis also present with choledocholithiasis. Guidelines from the European Society of Gastrointestinal Endoscopy (ESGE) and the American Society for Gastrointestinal Endoscopy (ASGE) for investigating suspected choledocholithiasis suggest endoscopic retrograde cholangiopancreatography in patients with high-likelihood (ESGE)/high-probability (ASGE) predictors and endoscopic ultrasound in those with intermediate-likelihood (ESGE)/intermediate-probability (ASGE) predictors. Although both guidelines are similar, they are not identical. Furthermore, these algorithms were mainly developed from cohorts of patients without pancreatitis and are therefore poorly validated in a subset of patients with acute pancreatitis. We aimed to assess the performance of the ESGE and ASGE algorithms for the prediction of choledocholithiasis in patients with acute biliary pancreatitis. Materials and Methods: This was a retrospective analysis of 86 consecutive patients admitted to a tertiary referral centre in the year 2020 due to acute biliary pancreatitis. Results: Choledocholithiasis was confirmed in 29/86 (33.7%) of patients (13 with endoscopic retrograde cholangiopancreatography and 16 with endoscopic ultrasound). All 10/10 (100%) ESGE high-likelihood and 14/19 (73.7%) ASGE high-probability patients had choledocholithiasis. Only 19/71 (26.8%) patients with ESGE intermediate likelihood and 15/67 (22.4%) with ASGE intermediate probability had choledocholithiasis. Only 8/13 (61.5%) patients with the ASGE high-probability predictor of dilated common bile duct plus bilirubin > 68.4 µmol/mL had choledocholithiasis. Since this predictor is not considered high likelihood by ESGE, this resulted in a superior specificity of the European compared to the American guideline (100% vs. 91.2%). Following the American instead of the European guidelines would have resulted in five unnecessary endoscopic retrograde cholangiopancreatographies and five unnecessary ...
    Keywords acute biliary pancreatitis ; endoscopic ultrasound ; ERCP ; choledocholithiasis ; ultrasound ; transabdominal ultrasound ; Medicine (General) ; R5-920
    Subject code 610
    Language English
    Publishing date 2023-12-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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