LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 665

Search options

  1. Article ; Online: Thyroid Dysfunction and Chronic Kidney Disease: Unravelling the Connection.

    Griffin, Tomás P / Griffin, Matthew D

    Mayo Clinic proceedings

    2023  Volume 99, Issue 1, Page(s) 7–9

    MeSH term(s) Humans ; Thyroid Diseases/complications ; Thyroid Diseases/diagnosis ; Renal Insufficiency, Chronic/complications
    Language English
    Publishing date 2023-11-30
    Publishing country England
    Document type Editorial
    ZDB-ID 124027-4
    ISSN 1942-5546 ; 0025-6196
    ISSN (online) 1942-5546
    ISSN 0025-6196
    DOI 10.1016/j.mayocp.2023.11.012
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article ; Online: Endothelial Expression of Class II MHC Proteins: A New Layer of Complexity in Kidney Transplantation.

    Griffin, Matthew D / Malone, Andrew F

    Journal of the American Society of Nephrology : JASN

    2023  Volume 34, Issue 5, Page(s) 727–729

    MeSH term(s) Histocompatibility Antigens Class II ; Kidney Transplantation ; Endothelium ; Kidney
    Chemical Substances Histocompatibility Antigens Class II
    Language English
    Publishing date 2023-03-24
    Publishing country United States
    Document type Research Support, N.I.H., Extramural ; Editorial ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 1085942-1
    ISSN 1533-3450 ; 1046-6673
    ISSN (online) 1533-3450
    ISSN 1046-6673
    DOI 10.1681/ASN.0000000000000115
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article ; Online: Immune Modulatory Cell Therapy in Kidney Transplantation: Hints of a Durable Mechanism of Action.

    Griffin, Matthew D / Perico, Norberto / Casiraghi, Federica

    Journal of the American Society of Nephrology : JASN

    2023  Volume 34, Issue 1, Page(s) 4–7

    MeSH term(s) Kidney Transplantation ; Humans ; Immunomodulation
    Language English
    Publishing date 2023-01-30
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 1085942-1
    ISSN 1533-3450 ; 1046-6673
    ISSN (online) 1533-3450
    ISSN 1046-6673
    DOI 10.1681/ASN.0000000000000007
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Article ; Online: Threading the Needle: Individualized Monitoring Guides the Transition From Cytomegalovirus Prophylaxis to Primary Immune Response in a Face Transplant Recipient.

    Griffin, Matthew D

    Mayo Clinic proceedings

    2019  Volume 94, Issue 1, Page(s) 10–12

    MeSH term(s) Cytomegalovirus ; Cytomegalovirus Infections ; Facial Transplantation ; Humans ; Kidney Transplantation ; Transplant Recipients
    Language English
    Publishing date 2019-01-04
    Publishing country England
    Document type Editorial ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 124027-4
    ISSN 1942-5546 ; 0025-6196
    ISSN (online) 1942-5546
    ISSN 0025-6196
    DOI 10.1016/j.mayocp.2018.11.015
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  5. Article: Editorial: Insights in renal pharmacology: 2021.

    Perico, Norberto / Griffin, Matthew D / Remuzzi, Giuseppe

    Frontiers in pharmacology

    2022  Volume 13, Page(s) 1010691

    Language English
    Publishing date 2022-09-07
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2022.1010691
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  6. Article ; Online: Could NAD

    Hyndman, Kelly A / Griffin, Matthew D

    Journal of the American Society of Nephrology : JASN

    2021  Volume 32, Issue 6, Page(s) 1270–1273

    MeSH term(s) Diabetes Mellitus ; Diabetic Nephropathies/prevention & control ; Dietary Supplements ; Humans ; NAD ; Sirtuin 1
    Chemical Substances NAD (0U46U6E8UK) ; Sirtuin 1 (EC 3.5.1.-)
    Language English
    Publishing date 2021-04-14
    Publishing country United States
    Document type Editorial ; Research Support, N.I.H., Extramural ; Comment
    ZDB-ID 1085942-1
    ISSN 1533-3450 ; 1046-6673
    ISSN (online) 1533-3450
    ISSN 1046-6673
    DOI 10.1681/ASN.2021020275
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  7. Article ; Online: Authors' Reply: Cell Therapies in Diabetic Kidney Disease: Is It Time for Clinical Translation?

    Perico, Norberto / Griffin, Matthew D / Casiraghi, Federica / Remuzzi, Giuseppe

    Journal of the American Society of Nephrology : JASN

    2023  Volume 34, Issue 12, Page(s) 2052–2053

    MeSH term(s) Humans ; Diabetic Nephropathies/therapy ; Cell- and Tissue-Based Therapy ; Diabetes Mellitus
    Language English
    Publishing date 2023-12-01
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 1085942-1
    ISSN 1533-3450 ; 1046-6673
    ISSN (online) 1533-3450
    ISSN 1046-6673
    DOI 10.1681/ASN.0000000000000231
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  8. Article ; Online: Revisiting regulatory T cells as modulators of innate immune response and inflammatory diseases.

    Ou, Qifeng / Power, Rachael / Griffin, Matthew D

    Frontiers in immunology

    2023  Volume 14, Page(s) 1287465

    Abstract: Regulatory T cells (Treg) are known to be critical for the maintenance of immune homeostasis by suppressing the activation of auto- or allo-reactive effector T cells through a diverse repertoire of molecular mechanisms. Accordingly, therapeutic ... ...

    Abstract Regulatory T cells (Treg) are known to be critical for the maintenance of immune homeostasis by suppressing the activation of auto- or allo-reactive effector T cells through a diverse repertoire of molecular mechanisms. Accordingly, therapeutic strategies aimed at enhancing Treg numbers or potency in the setting of autoimmunity and allogeneic transplants have been energetically pursued and are beginning to yield some encouraging outcomes in early phase clinical trials. Less well recognized from a translational perspective, however, has been the mounting body of evidence that Treg directly modulate most aspects of innate immune response under a range of different acute and chronic disease conditions. Recognizing this aspect of Treg immune modulatory function provides a bridge for the application of Treg-based therapies to common medical conditions in which organ and tissue damage is mediated primarily by inflammation involving myeloid cells (mononuclear phagocytes, granulocytes) and innate lymphocytes (NK cells, NKT cells, γδ T cells and ILCs). In this review, we comprehensively summarize pre-clinical and human research that has revealed diverse modulatory effects of Treg and specific Treg subpopulations on the range of innate immune cell types. In each case, we emphasize the key mechanistic insights and the evidence that Treg interactions with innate immune effectors can have significant impacts on disease severity or treatment. Finally, we discuss the opportunities and challenges that exist for the application of Treg-based therapeutic interventions to three globally impactful, inflammatory conditions: type 2 diabetes and its end-organ complications, ischemia reperfusion injury and atherosclerosis.
    MeSH term(s) Humans ; T-Lymphocytes, Regulatory ; Diabetes Mellitus, Type 2 ; Immunity, Innate ; Autoimmunity ; Inflammation
    Language English
    Publishing date 2023-10-20
    Publishing country Switzerland
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2023.1287465
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  9. Article ; Online: Conformational dynamicity in a copper(II) coordination complex.

    Griffin, Paul J / Dake, Matthew J / Remolina, Alesandro D / Olshansky, Lisa

    Dalton transactions (Cambridge, England : 2003)

    2023  Volume 52, Issue 24, Page(s) 8376–8383

    Abstract: The geometries of copper coordination complexes are intricately related to their electron transfer capabilities, but the role of dynamics in these processes are not fully understood. We have previously reported CuCl( ... ...

    Abstract The geometries of copper coordination complexes are intricately related to their electron transfer capabilities, but the role of dynamics in these processes are not fully understood. We have previously reported CuCl(dpa
    Language English
    Publishing date 2023-06-20
    Publishing country England
    Document type Journal Article
    ZDB-ID 1472887-4
    ISSN 1477-9234 ; 1364-5447 ; 0300-9246 ; 1477-9226
    ISSN (online) 1477-9234 ; 1364-5447
    ISSN 0300-9246 ; 1477-9226
    DOI 10.1039/d3dt01213a
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  10. Article: Editorial: Innovative Biologics and Drugs to Target Renal Inflammation.

    Griffin, Matthew D / Swaminathan, Sundararaman

    Frontiers in pharmacology

    2020  Volume 11, Page(s) 38

    Language English
    Publishing date 2020-02-06
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2020.00038
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top