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  1. Article ; Online: Breastfeeding and hemolytic uremic syndrome.

    Giordano, Mario / Gallo, Manuela / Ferrante, Maria Paola

    Pediatric nephrology (Berlin, Germany)

    2024  

    Language English
    Publishing date 2024-04-27
    Publishing country Germany
    Document type Letter
    ZDB-ID 631932-4
    ISSN 1432-198X ; 0931-041X
    ISSN (online) 1432-198X
    ISSN 0931-041X
    DOI 10.1007/s00467-024-06359-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Phase Diagram of Aqueous Solutions of LiCl: a Study of Concentration Effects on the Anomalies of Water.

    Perin, Leonardo / Gallo, Paola

    The journal of physical chemistry. B

    2023  Volume 127, Issue 20, Page(s) 4613–4622

    Abstract: We perform molecular dynamics simulations in order to study thermodynamics and the structure of supercooled aqueous solutions of lithium chloride (LiCl) at ... ...

    Abstract We perform molecular dynamics simulations in order to study thermodynamics and the structure of supercooled aqueous solutions of lithium chloride (LiCl) at concentrations
    Language English
    Publishing date 2023-05-11
    Publishing country United States
    Document type Journal Article
    ISSN 1520-5207
    ISSN (online) 1520-5207
    DOI 10.1021/acs.jpcb.3c00703
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Glassy dynamics of water in TIP4P/Ice aqueous solutions of trehalose in comparison with the bulk phase.

    Lupi, Laura / Gallo, Paola

    The Journal of chemical physics

    2022  Volume 159, Issue 15

    Abstract: We perform molecular dynamics simulations of TIP4P/Ice water in solution with trehalose for 3.65 and 18.57 wt. % concentrations and of bulk TIP4P/Ice water at ambient pressure, to characterize the structure and dynamics of water in a sugar aqueous ... ...

    Abstract We perform molecular dynamics simulations of TIP4P/Ice water in solution with trehalose for 3.65 and 18.57 wt. % concentrations and of bulk TIP4P/Ice water at ambient pressure, to characterize the structure and dynamics of water in a sugar aqueous solution in the supercooled region. We find here that TIP4P/Ice water in solution with trehalose molecules follows the Mode Coupling Theory and undergoes a fragile to strong transition up to the highest concentration investigated, similar to the bulk. Moreover, we perform a Mode Coupling Theory test, showing that the Time Temperature Superposition principle holds for both bulk TIP4P/Ice water and for TIP4P/Ice water in the solutions and we calculate the exponents of the theory. The direct comparison of the dynamical results for bulk water and water in the solutions shows upon cooling along the isobar a fastening of water dynamics for lower temperatures, T < 240 K. We found that the counter-intuitive behavior for the low temperature solutions can be explained with the diffusion anomaly of water leading us to the conclusion that the fastening observed below T = 240 K in water dynamics is only fictitious, due to the fact that the density of water molecules in the solutions is higher than the density of the bulk at the same temperature and pressure. This result should be taken into account in experimental investigations which are often carried out at constant pressure.
    Language English
    Publishing date 2022-09-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3113-6
    ISSN 1089-7690 ; 0021-9606
    ISSN (online) 1089-7690
    ISSN 0021-9606
    DOI 10.1063/5.0168933
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  4. Article ; Online: Upper Airway Dimensions among Different Skeletal Malocclusions: A Retrospective Observational Study by Cephalometric Analysis.

    Sfondrini, Maria Francesca / Gallo, Simone / Pascadopoli, Maurizio / Gandini, Paola / Roncoroni, Caterina / Scribante, Andrea

    Dentistry journal

    2024  Volume 12, Issue 1

    Abstract: The aim of the present work was to investigate the upper airway dimensions in adult non-orthodontic patients, equally divided according to their skeletal class.: Methods: In this retrospective cross-sectional study, lateral cephalometric radiographs ... ...

    Abstract The aim of the present work was to investigate the upper airway dimensions in adult non-orthodontic patients, equally divided according to their skeletal class.
    Methods: In this retrospective cross-sectional study, lateral cephalometric radiographs of adult patients referred for orthodontic consultation were collected. Cephalometric tracing was performed with dedicated software. For each measure, descriptive statistics were calculated. Cephalometric measurements between the different skeletal classes were compared. Linear regressions were performed between upper airway diameters and cephalometric measurements, sex and age. Significance was predetermined for
    Results: Lateral cephalometric radiographs of 120 patients were reviewed. Nasopharynx length (NL) and depth (PD) measurements were significantly shorter in skeletal class III patients (
    Conclusions: Class III patients show significantly shorter nasopharynx measurements; clinicians should consider that this sagittal discrepancy could be related to an altered anatomy of the upper respiratory tract.
    Language English
    Publishing date 2024-01-03
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2681351-8
    ISSN 2304-6767 ; 2304-6767
    ISSN (online) 2304-6767
    ISSN 2304-6767
    DOI 10.3390/dj12010012
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  5. Article ; Online: Prenatal Fluoxetine Exposure Influences Glucocorticoid Receptor-Mediated Activity in the Prefrontal Cortex of Adolescent Rats Exposed to Acute Stress.

    Gallo, Maria Teresa / Dolci, Beatrice / Fumagalli, Fabio / Brivio, Paola / Calabrese, Francesca

    ACS chemical neuroscience

    2024  Volume 15, Issue 7, Page(s) 1560–1569

    Abstract: Any deviation from the programmed processes of brain development may modify its formation and functions, thereby precipitating pathological conditions, which often become manifest in adulthood. Exposure to a challenge during crucial periods of ... ...

    Abstract Any deviation from the programmed processes of brain development may modify its formation and functions, thereby precipitating pathological conditions, which often become manifest in adulthood. Exposure to a challenge during crucial periods of vulnerability, such as adolescence, may reveal molecular changes preceding behavioral outcomes. Based on a previous study showing that prenatal fluoxetine (FLX) leads to the development of an anhedonic-like behavior in adult rats, we aimed to assess whether the same treatment regimen (i.e., fluoxetine during gestation; 15 mg/kg/day) influences the ability to respond to acute restraint stress (ARS) during adolescence. We subjected the rats to a battery of behavioral tests evaluating the development of various phenotypes (cognitive deficit, anhedonia, and anxiety). Furthermore, we carried out molecular analyses in the plasma and prefrontal cortex, a brain region involved in stress response, and whose functions are commonly altered in neuropsychiatric conditions. Our findings confirm that prenatal manipulation did not affect behavior in adolescent rats but impaired the capability to respond properly to ARS. Indeed, we observed changes in several molecular key players of the hypothalamic pituitary adrenal axis, particularly influencing genomic effects mediated by the glucocorticoid receptor. This study highlights that prenatal FLX exposure influences the ability of adolescent male rats to respond to an acute challenge, thereby altering the functionality of the hypothalamic-pituitary-adrenal axis, and indicates that the prenatal manipulation may prime the response to challenging events during this critical period of life.
    MeSH term(s) Female ; Pregnancy ; Rats ; Animals ; Male ; Humans ; Fluoxetine/pharmacology ; Selective Serotonin Reuptake Inhibitors ; Hypothalamo-Hypophyseal System ; Receptors, Glucocorticoid ; Pituitary-Adrenal System ; Prefrontal Cortex ; Stress, Psychological ; Prenatal Exposure Delayed Effects ; Corticosterone/pharmacology
    Chemical Substances Fluoxetine (01K63SUP8D) ; Selective Serotonin Reuptake Inhibitors ; Receptors, Glucocorticoid ; Corticosterone (W980KJ009P)
    Language English
    Publishing date 2024-03-20
    Publishing country United States
    Document type Journal Article
    ISSN 1948-7193
    ISSN (online) 1948-7193
    DOI 10.1021/acschemneuro.3c00856
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Siponimod-Related Bilateral Macular Edema: A Transient and Completely Reversible Disorder.

    Miscioscia, Alessandro / Rinaldi, Francesca / Pilotto, Elisabetta / Perini, Paola / Gallo, Paolo

    Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society

    2023  Volume 44, Issue 1, Page(s) e6–e7

    MeSH term(s) Humans ; Macular Edema/chemically induced ; Macular Edema/diagnosis ; Macular Edema/drug therapy ; Azetidines ; Benzyl Compounds
    Chemical Substances siponimod (RR6P8L282I) ; Azetidines ; Benzyl Compounds
    Language English
    Publishing date 2023-01-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1189901-3
    ISSN 1536-5166 ; 1070-8022
    ISSN (online) 1536-5166
    ISSN 1070-8022
    DOI 10.1097/WNO.0000000000001788
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  7. Article ; Online: Lifestyle Modulators of Neuroplasticity in Parkinson's Disease: Evidence in Human Neuroimaging Studies.

    Paola Caminiti, Silvia / Gallo, Silvia / Menegon, Federico / Naldi, Andrea / Comi, Cristoforo / Tondo, Giacomo

    CNS & neurological disorders drug targets

    2023  Volume 23, Issue 5, Page(s) 602–613

    Abstract: Parkinson's disease (PD) is a neurodegenerative disease characterized by both motor and non-motor symptoms. A progressive neuronal loss and the consequent clinical impairment lead to deleterious effects on daily living and quality of life. Despite ... ...

    Abstract Parkinson's disease (PD) is a neurodegenerative disease characterized by both motor and non-motor symptoms. A progressive neuronal loss and the consequent clinical impairment lead to deleterious effects on daily living and quality of life. Despite effective symptomatic therapeutic approaches, no disease-modifying therapies are currently available. Emerging evidence suggests that adopting a healthy lifestyle can improve the quality of life of PD patients. In addition, modulating lifestyle factors can positively affect the microstructural and macrostructural brain levels, corresponding to clinical improvement. Neuroimaging studies may help to identify the mechanisms through which physical exercise, dietary changes, cognitive enrichment, and exposure to substances modulate neuroprotection. All these factors have been associated with a modified risk of developing PD, with attenuation or exacerbation of motor and non-motor symptomatology, and possibly with structural and molecular changes. In the present work, we review the current knowledge on how lifestyle factors influence PD development and progression and the neuroimaging evidence for the brain structural, functional, and molecular changes induced by the adoption of positive or negative lifestyle behaviours.
    MeSH term(s) Humans ; Parkinson Disease/diagnostic imaging ; Neuroimaging/methods ; Life Style ; Neuronal Plasticity/physiology ; Brain/diagnostic imaging ; Exercise/physiology ; Quality of Life
    Language English
    Publishing date 2023-06-16
    Publishing country United Arab Emirates
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2228394-8
    ISSN 1996-3181 ; 1871-5273
    ISSN (online) 1996-3181
    ISSN 1871-5273
    DOI 10.2174/1871527322666230616121213
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Drought-Adapted Mediterranean Diet Plants: A Source of Bioactive Molecules Able to Give Nutrigenomic Effects per sè or to Obtain Functional Foods.

    La Scala, Silvia / Naselli, Flores / Quatrini, Paola / Gallo, Giuseppe / Caradonna, Fabio

    International journal of molecular sciences

    2024  Volume 25, Issue 4

    Abstract: The Mediterranean diet features plant-based foods renowned for their health benefits derived from bioactive compounds. This review aims to provide an overview of the bioactive molecules present in some representative Mediterranean diet plants, examining ... ...

    Abstract The Mediterranean diet features plant-based foods renowned for their health benefits derived from bioactive compounds. This review aims to provide an overview of the bioactive molecules present in some representative Mediterranean diet plants, examining their human nutrigenomic effects and health benefits as well as the environmental advantages and sustainability derived from their cultivation. Additionally, it explores the facilitation of producing fortified foods aided by soil and plant microbiota properties. Well-studied examples, such as extra virgin olive oil and citrus fruits, have demonstrated significant health advantages, including anti-cancer, anti-inflammatory, and neuroprotective effects. Other less renowned plants are presented in the scientific literature with their beneficial traits on human health highlighted. Prickly pear's indicaxanthin exhibits antioxidant properties and potential anticancer traits, while capers kaempferol and quercetin support cardiovascular health and prevent cancer. Oregano and thyme, containing terpenoids like carvacrol and γ-terpinene, exhibit antimicrobial effects. Besides their nutrigenomic effects, these plants thrive in arid environments, offering benefits associated with their cultivation. Their microbiota, particularly Plant Growth Promoting (PGP) microorganisms, enhance plant growth and stress tolerance, offering biotechnological opportunities for sustainable agriculture. In conclusion, leveraging plant microbiota could revolutionize agricultural practices and increase sustainability as climate change threatens biodiversity. These edible plant species may have crucial importance, not only as healthy products but also for increasing the sustainability of agricultural systems.
    MeSH term(s) Humans ; Diet, Mediterranean ; Functional Food ; Nutrigenomics ; Droughts ; Plants, Edible
    Language English
    Publishing date 2024-02-13
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms25042235
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  9. Article ; Online: Several glasses of water but one dense liquid.

    Gallo, Paola / Sciortino, Francesco

    Proceedings of the National Academy of Sciences of the United States of America

    2019  Volume 116, Issue 19, Page(s) 9149–9151

    Language English
    Publishing date 2019-04-26
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 209104-5
    ISSN 1091-6490 ; 0027-8424
    ISSN (online) 1091-6490
    ISSN 0027-8424
    DOI 10.1073/pnas.1904692116
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  10. Article ; Online: The short stump and high anastomosis pull-through procedure for delayed coloanal anastomosis with no protective stoma for low rectal cancer - a video vignette.

    Bianco, Francesco / Novi, Alessandra / Incollingo, Paola / Gallo, Gaetano / Grassia, Sebastiano

    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland

    2022  Volume 24, Issue 6, Page(s) 801–802

    MeSH term(s) Anal Canal/surgery ; Anastomosis, Surgical/methods ; Colon/surgery ; Digestive System Surgical Procedures ; Humans ; Rectal Neoplasms/surgery ; Surgical Stomas
    Language English
    Publishing date 2022-02-23
    Publishing country England
    Document type Letter ; Video-Audio Media
    ZDB-ID 1440017-0
    ISSN 1463-1318 ; 1462-8910
    ISSN (online) 1463-1318
    ISSN 1462-8910
    DOI 10.1111/codi.16087
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