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Article ; Online: El pensamiento político de Fernando González Ochoa

Damián Pachón Soto

Ciencia Política, Vol 10, Iss

del Rastacuerismo a la Autoexpresión del individuo

2015 Volume 20

Abstract: Esta investigación aborda el pensamiento político de Fernando González a partir del análisis ...

Abstract	Esta investigación aborda el pensamiento político de Fernando González a partir del análisis de la relación entre los siguientes conceptos: rastacuerismo, vanidad, identidad y diversidad. Asimismo, se patentiza la relación que existe entre los mismos con la noción de “el Otro” presente en sus análisis. Se muestra que el concepto de vanidad es sinónimo del rastacuerismo y que constituye la identidad del ser nacional latinoamericano, a la vez que la actualización del proyecto de la Gran Colombia implica una identidad política que no sólo reconoce la diversidad sino que permite clausurar la identidad patológica del latinoamericano. En González el proyecto político tiene como fin superar el rastacuerismo y llegar a un orden social donde prime la libertad y la autenticidad del individuo, esto es, la egoencia.
Keywords	rastacuerismo ; vanidad ; diversidad ; el Otro ; Gran Colombia ; cultura ; Political science ; J ; Political institutions and public administration (General) ; JF20-2112 ; Political science (General) ; JA1-92
Language	English
Publishing date	2015-07-01T00:00:00Z
Publisher	Universidad Nacional de Colombia
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Trends in Mortality from Ischemic Heart Disease in the Region of the Americas, 2000-2019.

Lanas, Fernando / Soto, Alvaro

Global heart

2022 Volume 17, Issue 1, Page(s) 53

Abstract: Background: In latest decades, mortality rates from ischemic heart disease (IHD) had declined steadily in most of the world as a consequence of improvements in prevention and therapy.: Objective: The aim of this study was to analyze trends in ... ...

Abstract	Background: In latest decades, mortality rates from ischemic heart disease (IHD) had declined steadily in most of the world as a consequence of improvements in prevention and therapy. Objective: The aim of this study was to analyze trends in mortality caused by IHD in the region of the Americas from 2000 to 2019. Methods: Estimates of the age-adjusted mortality rate (AAMR) due to IHD were extracted from the Data Portal on Noncommunicable Diseases, Mental Health, and External Causes (ENLACE), Pan American Health Organization. We used Joinpoint regression to analyze significant changes in mortality trends by country, gender, geographical sub-region, and country income, according to the World Bank classification. We also calculated the average annual percent change (AAPC) mortality rate for the overall period in the Americas as a whole and by country and sub-region. Results: In the region of the Americas, the AAMR from IHD decreased from 117.80 (95% uncertainty interval (UI)) 106.64-135.90) in 2000 to 73.64 (62.65-92.66) per 100,000 in 2019. In males, from 149.08 (95% UI 138.23-168.08) to 96.02 (95% UI 83.48-117.19) and in females 92.36 (95% UI 81.35-109.42) to 54.84 (95% UI 45.28-71.76). The AAPC mortality rate in the region decreased -2.5% (95% CI: -2.7, -2.3), with joinpoints in 2007 and 2012, -2.3% (95% CI: -2.5, -2.1) in men and -2.7% (95% CI: -3.0, -2.5) in women. According to the sub-region analysis, the highest decrease was recorded in North America, AAPC -3.1% (95% CI: -3.3, -3.0) with one joinpoint in 2011, whereas there was a stagnation of the mortality rate in Central America, Mexico, and Latin Caribbean with an AAPC of 0.1 (-0.2, 0.3) with one joinpoint in 2007. Conclusions: Age-adjusted mortality rate from IHD between 2000 and 2019 has decreased in the region of the Americas. However, different trends were observed, North America had the highest reduction in AAPC, while Central America, Mexico, and Latin Caribbean Region had a stagnation. This trend was highly influenced by country income.
MeSH term(s)	Americas/epidemiology ; Caribbean Region ; Female ; Humans ; Male ; Mexico ; Mortality ; Myocardial Ischemia ; North America
Language	English
Publishing date	2022-08-11
Publishing country	England
Document type	Journal Article
ZDB-ID	2629633-0
ISSN	2211-8179 ; 2211-8160
ISSN (online)	2211-8179
ISSN	2211-8160
DOI	10.5334/gh.1144
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: ENDOMETRIOSIS CERVICAL SUPERFICIAL

Carlos Fernando Avilez Soto

Ciencia Médica, Vol 24, Iss

REPORTE DE CASO

2022 Volume 2

Abstract: ENDOMETRIOSIS CERVICAL SUPERFICIAL: REPORTE DE ... ...

Abstract	ENDOMETRIOSIS CERVICAL SUPERFICIAL: REPORTE DE CASO
Keywords	Medicine (General) ; R5-920
Language	Spanish
Publishing date	2022-03-01T00:00:00Z
Publisher	Universidad Mayor de San Simón, Facultad de Medicina
Document type	Article ; Online
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Article ; Online: Trends in Mortality from Ischemic Heart Disease in the Region of the Americas, 2000–2019

Fernando Lanas / Alvaro Soto

Global Heart, Vol 17, Iss

2022 Volume 1

Abstract: Background: In latest decades, mortality rates from ischemic heart disease (IHD) had declined steadily in most of the world as a consequence of improvements in prevention and therapy. Objective: The aim of this study was to analyze trends in mortality ... ...

Abstract	Background: In latest decades, mortality rates from ischemic heart disease (IHD) had declined steadily in most of the world as a consequence of improvements in prevention and therapy. Objective: The aim of this study was to analyze trends in mortality caused by IHD in the region of the Americas from 2000 to 2019. Methods: Estimates of the age-adjusted mortality rate (AAMR) due to IHD were extracted from the Data Portal on Noncommunicable Diseases, Mental Health, and External Causes (ENLACE), Pan American Health Organization. We used Joinpoint regression to analyze significant changes in mortality trends by country, gender, geographical sub-region, and country income, according to the World Bank classification. We also calculated the average annual percent change (AAPC) mortality rate for the overall period in the Americas as a whole and by country and sub-region. Results: In the region of the Americas, the AAMR from IHD decreased from 117.80 (95% uncertainty interval (UI)) 106.64–135.90) in 2000 to 73.64 (62.65–92.66) per 100,000 in 2019. In males, from 149.08 (95% UI 138.23–168.08) to 96.02 (95% UI 83.48–117.19) and in females 92.36 (95% UI 81.35–109.42) to 54.84 (95% UI 45.28–71.76). The AAPC mortality rate in the region decreased –2.5% (95% CI: –2.7, –2.3), with joinpoints in 2007 and 2012, –2.3% (95% CI: –2.5, –2.1) in men and –2.7% (95% CI: –3.0, –2.5) in women. According to the sub-region analysis, the highest decrease was recorded in North America, AAPC –3.1% (95% CI: –3.3, –3.0) with one joinpoint in 2011, whereas there was a stagnation of the mortality rate in Central America, Mexico, and Latin Caribbean with an AAPC of 0.1 (–0.2, 0.3) with one joinpoint in 2007. Conclusions: Age-adjusted mortality rate from IHD between 2000 and 2019 has decreased in the region of the Americas. However, different trends were observed, North America had the highest reduction in AAPC, while Central America, Mexico, and Latin Caribbean Region had a stagnation. This trend was highly influenced by country income.
Keywords	americas region ; ischemic heart disease ; mortality ; joinpoint ; Diseases of the circulatory (Cardiovascular) system ; RC666-701 ; Public aspects of medicine ; RA1-1270
Subject code	310
Language	English
Publishing date	2022-08-01T00:00:00Z
Publisher	Ubiquity Press
Document type	Article ; Online
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Article ; Online: Serum-ascites albumin gradient - A false dichotomy in the approach to ascites.

Núñez, Isaac / Solis-Huerta, Fernando / Soto-Mota, Adrian

European journal of internal medicine

2022 Volume 102, Page(s) 131–132

MeSH term(s)	Ascites ; Humans ; Hypertension, Portal ; Liver Cirrhosis ; Serum Albumin/analysis
Chemical Substances	Serum Albumin
Language	English
Publishing date	2022-04-15
Publishing country	Netherlands
Document type	Letter
ZDB-ID	1038679-8
ISSN	1879-0828 ; 0953-6205
ISSN (online)	1879-0828
ISSN	0953-6205
DOI	10.1016/j.ejim.2022.04.010
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Article ; Online: La comunicación en los museos durante el periodo de pandemia por COVID-19 a través de canales digitales. El caso del Museo del Desierto en Coahuila (México)

Sara Suleyma Rivera Soto / Luis Fernando Villegas García

Les Cahiers ALHIM, Vol

2023 Volume 44

Abstract: Museums as a possibility of historicity, cultural democratization and open dialogue require a constant review and questioning of their objectives and social commitment. During the recent COVID-19 pandemic, museums as educational spaces found it necessary ...

Abstract	Museums as a possibility of historicity, cultural democratization and open dialogue require a constant review and questioning of their objectives and social commitment. During the recent COVID-19 pandemic, museums as educational spaces found it necessary to find new ways to communicate with the public that frequented the venues on a daily basis. The present work arises from the concern that was generated to know the strategies that were implemented in the Museum of the Desert, which increased its interaction in social networks and allowed to have a greater reach with its audience. In this regard, Juan Carlos Mantilla, head of the communication department, gave an interview in which the technical aspects and the results of this interaction could be known. Following the precepts of Ma. Inmaculada Pastor Homs and Joseph Ballart, which address the concepts of the educational work of museums and the formation of audiences, the work is articulated in 5 sections that range from the analysis of the museum in the face of the challenges brought about by the pandemic to the meeting space in the Museum of the Desert.
Keywords	museums ; museum pedagogy ; digital communication ; Desert Museum ; art ; exhibitions ; Latin America. Spanish America ; F1201-3799 ; Social Sciences ; H
Subject code	700
Language	Spanish
Publishing date	2023-01-01T00:00:00Z
Publisher	Groupe de Recherche Amérique Latine Histoire et Mémoire
Document type	Article ; Online
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Article: Union Instability and Fertility: An International Perspective.

Fostik, Ana / Fernández Soto, Mariana / Ruiz-Vallejo, Fernando / Ciganda, Daniel

European journal of population = Revue europeenne de demographie

2023 Volume 39, Issue 1, Page(s) 25

Abstract: In this article, we analyse the relationship between union instability and cumulated fertility among ever-partnered women in several regions across Europe and the Americas with different patterns of demographic behaviour in terms of fertility levels, ... ...

Abstract	In this article, we analyse the relationship between union instability and cumulated fertility among ever-partnered women in several regions across Europe and the Americas with different patterns of demographic behaviour in terms of fertility levels, union instability and fertility across partnerships. We hypothesise that the relationship between union dissolution and fertility might be less negative in contexts where repartnering is more prevalent. The analysis is performed on a large dataset of 25 countries, combining information from the Harmonised Histories of the Generation and Gender Programme with our own harmonisation of survey data from three Latin American countries. This allows for the inclusion of countries with differing prevalence of union instability as measured by (a) the proportion of women who separated by age 40, and (b) the proportion who repartnered by age 40. We first examine the prevalence of separation and repartnering during reproductive ages across regions, and we estimate the proportion of cumulated fertility attributable to unions of different ranks using a decomposition method. We then analyse the links between union instability and the number of children born by age 40 among ever-partnered and ever-repartnered women, using Poisson regression. Despite observing a high degree of heterogeneity in the proportions of births occurring in the context of repartnering both within and between regions, we find a pattern where a greater prevalence of repartnering by age 40 is accompanied by higher cumulated fertility in second or subsequent unions. Our multivariate findings reveal a negative statistical relationship between separation and cumulated fertility that is partially offset by repartnering in some contexts, and that the time spent in a union during the reproductive lifespan is a key determinant of cumulated fertility, regardless of national context and independently from age at union formation and union rank.
Language	English
Publishing date	2023-07-20
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	2015429-X
ISSN	1572-9885 ; 0168-6577
ISSN (online)	1572-9885
ISSN	0168-6577
DOI	10.1007/s10680-023-09668-1
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Article ; Online: Effect of Composition and Freeze-Thaw on the Network Structure, Porosity and Mechanical Properties of Polyvinyl-Alcohol/Chitosan Hydrogels.

Soto-Bustamante, Fernando / Bassu, Gavino / Fratini, Emiliano / Laurati, Marco

Gels (Basel, Switzerland)

2023 Volume 9, Issue 5

Abstract: We report the synthesis and characterization of poly (vinyl alcohol) (PVA)/Chitosan (CT) cryogels for applications involving the uptake and entrapment of particulate and bacterial colonies. In particular, we systematically investigated the network and ... ...

Abstract	We report the synthesis and characterization of poly (vinyl alcohol) (PVA)/Chitosan (CT) cryogels for applications involving the uptake and entrapment of particulate and bacterial colonies. In particular, we systematically investigated the network and pore structures of the gels as a function of CT content and for different freeze-thaw times, combining Small Angle X-Ray Scattering (SAXS), Scanning Electron Microscopy (SEM), and confocal microscopy. The nanoscale analysis obtained from SAXS shows that while the characteristic correlation length of the network is poorly affected by composition and freeze-thaw time, the characteristic size of heterogeneities associated with PVA crystallites decreases with CT content. SEM investigation evidences a transition to a more homogeneous network structure induced by the incorporation of CT that progressively builds a secondary network around the one formed by PVA. A detailed analysis of confocal microscopy image stacks allows to characterize the 3D porosity of the samples, revealing a significantly asymmetric shape of the pores. While the average volume of single pores increases with increasing CT content, the overall porosity remains almost unchanged as a result of the suppression of smaller pores in the PVA network with the progressive incorporation of the more homogeneous CT network. Increasing the freezing time in the FT cycles also results in a decrease of porosity, which can be associated with a growth in the crosslinking of the network due to PVA crystallization. The linear viscoelastic moduli measured by oscillatory rheology show a qualitatively comparable frequency-dependent response in all cases, with a moderate reduction with increasing CT content. This is attributed to changes in the structure of the strands of the PVA network.
Language	English
Publishing date	2023-05-09
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2813982-3
ISSN	2310-2861 ; 2310-2861
ISSN (online)	2310-2861
ISSN	2310-2861
DOI	10.3390/gels9050396
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Article: Systematic review and bioinformatics analysis of plasma and serum extracellular vesicles proteome in type 2 diabetes.

Arredondo-Damián, Jeanette Guadalupe / Martínez-Soto, Juan Manuel / Molina-Pelayo, Francisco A / Soto-Guzmán, Jesús Adriana / Castro-Sánchez, Luis / López-Soto, Luis Fernando / Candia-Plata, Maria Del Carmen

Heliyon

2024 Volume 10, Issue 3, Page(s) e25537

Abstract: Background: Type 2 diabetes (T2D) is a complex metabolic ailment marked by a global high prevalence and significant attention in primary healthcare settings due to its elevated morbidity and mortality rates. The pathophysiological mechanisms underlying ... ...

Abstract	Background: Type 2 diabetes (T2D) is a complex metabolic ailment marked by a global high prevalence and significant attention in primary healthcare settings due to its elevated morbidity and mortality rates. The pathophysiological mechanisms underlying the onset and progression of this disease remain subjects of ongoing investigation. Recent evidence underscores the pivotal role of the intricate intercellular communication network, wherein cell-derived vesicles, commonly referred to as extracellular vesicles (EVs), emerge as dynamic regulators of diabetes-related complications. Given that the protein cargo carried by EVs is contingent upon the metabolic conditions of the originating cells, particular proteins may serve as informative indicators for the risk of activating or inhibiting signaling pathways crucial to the progression of T2D complications. Methods: In this study, we conducted a systematic review to analyze the published evidence on the proteome of EVs from the plasma or serum of patients with T2D, both with and without complications (PROSPERO: CRD42023431464). Results: Nine eligible articles were systematically identified from the databases, and the proteins featured in these articles underwent Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis. We identified changes in the level of 426 proteins, with CST6, CD55, HBA1, S100A8, and S100A9 reported to have high levels, while FGL1 exhibited low levels. Conclusion: These proteins are implicated in pathophysiological mechanisms such as inflammation, complement, and platelet activation, suggesting their potential as risk markers for T2D development and progression. Further studies are required to explore this topic in greater detail.
Language	English
Publishing date	2024-02-05
Publishing country	England
Document type	Journal Article
ZDB-ID	2835763-2
ISSN	2405-8440
ISSN	2405-8440
DOI	10.1016/j.heliyon.2024.e25537
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Article ; Online: Epitope-Evaluator: An interactive web application to study predicted T-cell epitopes.

Soto, Luis Fernando / Requena, David / Fuxman Bass, Juan Ignacio

PloS one

2022 Volume 17, Issue 8, Page(s) e0273577

Abstract: Multiple immunoinformatic tools have been developed to predict T-cell epitopes from protein amino acid sequences for different major histocompatibility complex (MHC) alleles. These prediction tools output hundreds of potential peptide candidates which ... ...

Abstract	Multiple immunoinformatic tools have been developed to predict T-cell epitopes from protein amino acid sequences for different major histocompatibility complex (MHC) alleles. These prediction tools output hundreds of potential peptide candidates which require further processing; however, these tools are either not graphical or not friendly for non-programming users. We present Epitope-Evaluator, a web tool developed in the Shiny/R framework to interactively analyze predicted T-cell epitopes. Epitope-Evaluator contains six tools providing the distribution of epitopes across a selected set of MHC alleles, the promiscuity and conservation of epitopes, and their density and location within antigens. Epitope-Evaluator requires as input the fasta file of protein sequences and the output prediction file coming out from any predictor. By choosing different cutoffs and parameters, users can produce several interactive plots and tables that can be downloaded as JPG and text files, respectively. Using Epitope-Evaluator, we found the HLA-B40, HLA-B27:05 and HLA-B*07:02 recognized fewer epitopes from the SARS-CoV-2 proteome than other MHC Class I alleles. We also identified shared epitopes between Delta, Omicron, and Wuhan Spike variants as well as variant-specific epitopes. In summary, Epitope-Evaluator removes the programming barrier and provides intuitive tools, allowing a straightforward interpretation and graphical representations that facilitate the selection of candidate epitopes for experimental evaluation. The web server Epitope-Evaluator is available at https://fuxmanlab.shinyapps.io/Epitope-Evaluator/.
MeSH term(s)	COVID-19 ; Epitopes, T-Lymphocyte ; HLA-B Antigens ; Histocompatibility Antigens Class I ; Humans ; SARS-CoV-2
Chemical Substances	Epitopes, T-Lymphocyte ; HLA-B Antigens ; Histocompatibility Antigens Class I
Language	English
Publishing date	2022-08-26
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0273577
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