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  1. Article ; Online: Latest Developments and Current Problems in Bladder Cancer.

    Compérat, Eva

    World journal of urology

    2021  Volume 39, Issue 11, Page(s) 4009–4010

    MeSH term(s) Humans ; Neoplasm Staging ; Predictive Value of Tests ; Survival Rate ; Urinary Bladder Neoplasms/diagnosis ; Urinary Bladder Neoplasms/mortality ; Urinary Bladder Neoplasms/therapy
    Language English
    Publishing date 2021-10-21
    Publishing country Germany
    Document type Editorial
    ZDB-ID 380333-8
    ISSN 1433-8726 ; 0724-4983
    ISSN (online) 1433-8726
    ISSN 0724-4983
    DOI 10.1007/s00345-021-03857-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1832: Show issues Location:
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  2. Article ; Online: Editorial for Cribriform architecture prostatic adenocarcinoma in needle biopsy is a strong independent predictor for lymph node metastases in radical prostatectomy (M. Downes et al.) and Ductal variant prostate carcinoma is associated with a significantly shorter metastasis-free survival (K. Chow et al.).

    Compérat, Eva

    European journal of cancer (Oxford, England : 1990)

    2021  Volume 148, Page(s) 430–431

    MeSH term(s) Adenocarcinoma/surgery ; Biopsy, Needle ; Carcinoma ; Humans ; Lymphatic Metastasis ; Male ; Prostate ; Prostatectomy ; Prostatic Neoplasms/surgery
    Language English
    Publishing date 2021-02-19
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 82061-1
    ISSN 1879-0852 ; 0277-5379 ; 0959-8049 ; 0964-1947
    ISSN (online) 1879-0852
    ISSN 0277-5379 ; 0959-8049 ; 0964-1947
    DOI 10.1016/j.ejca.2021.01.023
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 456: Show issues Location:
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    Zs.MO 583: Show issues

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  3. Article ; Online: Re: Greater Utility of Molecular Subtype Rather than Epithelial-to-mesenchymal Transition (EMT) Markers for Prognosis in High-risk Non-muscle-invasive (HGT1) Bladder Cancer.

    Compérat, Eva

    European urology

    2020  Volume 78, Issue 5, Page(s) 764

    MeSH term(s) Biomarkers ; Epithelial-Mesenchymal Transition ; Humans ; Prognosis ; Urinary Bladder Neoplasms/genetics
    Chemical Substances Biomarkers
    Language English
    Publishing date 2020-07-04
    Publishing country Switzerland
    Document type Journal Article ; Comment
    ZDB-ID 193790-x
    ISSN 1873-7560 ; 1421-993X ; 0302-2838
    ISSN (online) 1873-7560 ; 1421-993X
    ISSN 0302-2838
    DOI 10.1016/j.eururo.2020.06.019
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    Zs.A 1247: Show issues Location:
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    Zs.MO 294: Show issues

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  4. Article ; Online: What Does COVID-19 Mean for the Pathology-Urology Interaction?

    Compérat, Eva

    European urology

    2020  Volume 78, Issue 1, Page(s) e43–e44

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections/complications ; Coronavirus Infections/epidemiology ; Diagnostic Techniques, Urological ; Humans ; Interprofessional Relations ; Pandemics ; Pneumonia, Viral/complications ; Pneumonia, Viral/epidemiology ; SARS-CoV-2 ; Urologic Diseases/complications ; Urologic Diseases/diagnosis ; Urology/methods
    Keywords covid19
    Language English
    Publishing date 2020-04-07
    Publishing country Switzerland
    Document type Letter
    ZDB-ID 193790-x
    ISSN 1873-7560 ; 1421-993X ; 0302-2838
    ISSN (online) 1873-7560 ; 1421-993X
    ISSN 0302-2838
    DOI 10.1016/j.eururo.2020.03.041
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Panel Comparative Analysis Tool: An Open-Source Comparative Analysis Tool for Next-Generation Sequencing Panel Target Regions.

    Oszwald, André / Zisser, Lucia / Compérat, Eva / Müllauer, Leonhard

    The Journal of molecular diagnostics : JMD

    2024  Volume 26, Issue 5, Page(s) 423–429

    Abstract: Multigene next-generation sequencing (NGS) panels have become a routine diagnostic method in the contemporary practice of personalized medicine. To avoid inadequate test choice or interpretation, a detailed understanding of the precise panel target ... ...

    Abstract Multigene next-generation sequencing (NGS) panels have become a routine diagnostic method in the contemporary practice of personalized medicine. To avoid inadequate test choice or interpretation, a detailed understanding of the precise panel target regions is required. However, the necessary bioinformatic expertise is not always available, and publicly accessible and easily interpretable analyses of target regions are scarce. To address this critical knowledge gap, we present the Panel Comparative Analysis Tool (PanelCAT), an open-source application to analyze, visualize, and compare NGS panel DNA target regions. PanelCAT uses Reference Sequence, ClinVar, and Catalogue of Somatic Mutations in Cancer mutation census databases to quantify the exon and mutation coverage of target regions and provides interactive graphical representations and search functions to inspect the results. We demonstrate the utility of PanelCAT by analyzing two large NGS panels (TruSight Oncology 500 and Human Pan Cancer Panel) to validate the advertised target genes, quantify targeted exons and mutations, and identify differences between panels. PanelCAT will enable institutions and researchers to catalog and visualize NGS panel target regions independent of the manufacturer, promote transparency of panel limitations, and share this information with employees and requisitioners.
    MeSH term(s) Humans ; Mutation ; Neoplasms/diagnosis ; Neoplasms/genetics ; Computational Biology ; Exons ; High-Throughput Nucleotide Sequencing/methods
    Language English
    Publishing date 2024-03-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2000060-1
    ISSN 1943-7811 ; 1525-1578
    ISSN (online) 1943-7811
    ISSN 1525-1578
    DOI 10.1016/j.jmoldx.2024.01.015
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5146: Show issues Location:
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  6. Article: New markers in prostate cancer: Inmunohistochemical.

    Compérat, Eva

    Archivos espanoles de urologia

    2019  Volume 72, Issue 2, Page(s) 126–134

    Abstract: Although pathology is the gold standard for confirming the diagnosis of prostate cancer (PCa), several marker for diagnosis may be useful and will helpin doubtful cases to confirm the diagnosis of PCa. Therfore it is important to spread the knowledge of ... ...

    Title translation Nuevos marcadores en cáncer de próstata: Inmunohistoquímica.
    Abstract Although pathology is the gold standard for confirming the diagnosis of prostate cancer (PCa), several marker for diagnosis may be useful and will helpin doubtful cases to confirm the diagnosis of PCa. Therfore it is important to spread the knowledge of immunomarker, in order to improve the clinicians understanding of stains and their usefulness. Like in other organs, clinicians and pathologists would like not to rely only on pathological criteria such as PSA, Gleason score, tumor size and pT stage, but also on tumor stains, permitting to predict prognosis and patients outcome, especially in patients with intermediate risk. Many markers have been proposed, but none is at the very moment approuved for current use.
    MeSH term(s) Biomarkers ; Biomarkers, Tumor ; Humans ; Immunohistochemistry ; Male ; Neoplasm Grading ; Prognosis ; Prostate-Specific Antigen ; Prostatic Neoplasms/diagnosis ; Prostatic Neoplasms/immunology
    Chemical Substances Biomarkers ; Biomarkers, Tumor ; Prostate-Specific Antigen (EC 3.4.21.77)
    Language English
    Publishing date 2019-03-07
    Publishing country Spain
    Document type Journal Article
    ZDB-ID 211673-x
    ISSN 0004-0614
    ISSN 0004-0614
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.B 1312: Show issues Location:
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  7. Article ; Online: Evolution of prostate cancer histopathology.

    Compérat, Eva

    Current opinion in urology

    2019  Volume 29, Issue 6, Page(s) 587–592

    Abstract: Purpose of review: During the last 15 years several updates in the Gleason grading have been made. With the help of pertinent research results pathologists have gained a better insight into the meanings of several prostate cancer (PCa) patterns and know ...

    Abstract Purpose of review: During the last 15 years several updates in the Gleason grading have been made. With the help of pertinent research results pathologists have gained a better insight into the meanings of several prostate cancer (PCa) patterns and know better how to classify them in the Gleason grade system.
    Recent findings: During the last years PCa with cribriform architecture has be given much attention. Many data have also been published about the meaning of comedonecrosis and its relationship with Gleason pattern 4 and 5. The correlationship between comedonecrosis and intraductal PCa has also been highlighted in the recent literature. Intraductal PCa is one of the most described topics at the moment with implications to treatment such as radiation therapy. We also highlight several practical issues such as the differences of grading in prostate biopsies and prostatectomies and describe the problematic of reporting a minor high-grade pattern.
    Summary: Many new and recent data have allowed to refine diagnosis in PCa and improve the patients's treatment. We show that comedonecrosis can be overgraded and insist on the implication with cribriform and intraducatal carcinomas. Furthermore, we describe the importance of these PCa types especially in the consideration of further treatment.
    MeSH term(s) Biopsy ; Carcinoma, Ductal/pathology ; Humans ; Image-Guided Biopsy/methods ; Male ; Neoplasm Grading/methods ; Prostatectomy/methods ; Prostatic Neoplasms/pathology ; Prostatic Neoplasms/surgery ; Ultrasonography, Interventional
    Language English
    Publishing date 2019-08-19
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1091792-5
    ISSN 1473-6586 ; 0963-0643
    ISSN (online) 1473-6586
    ISSN 0963-0643
    DOI 10.1097/MOU.0000000000000669
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 3345: Show issues Location:
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  8. Article ; Online: Changes of Tumour-Node-Metastasis Staging in 2017: Concepts and Evolutions in the European and American Continents.

    Compérat, Eva

    European urology

    2018  Volume 73, Issue 4, Page(s) 570–571

    MeSH term(s) Humans ; Lymph Nodes ; Neoplasm Staging ; Neoplasms ; United States
    Language English
    Publishing date 2018-01-11
    Publishing country Switzerland
    Document type Editorial ; Comment
    ZDB-ID 193790-x
    ISSN 1873-7560 ; 1421-993X ; 0302-2838
    ISSN (online) 1873-7560 ; 1421-993X
    ISSN 0302-2838
    DOI 10.1016/j.eururo.2018.01.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: What Does COVID-19 Mean for the Pathology-Urology Interaction?

    Compérat, Eva

    European Urology

    2020  Volume 78, Issue 1, Page(s) e43–e44

    Keywords Urology ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ZDB-ID 193790-x
    ISSN 1421-993X ; 0302-2838
    ISSN (online) 1421-993X
    ISSN 0302-2838
    DOI 10.1016/j.eururo.2020.03.041
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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