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  1. Article: Granulin-FTLD Presenting as Mixed Transcortical Aphasia: New Kid on the Block?

    Agarwal, Ayush / Makkar, Ayush M / Garg, Ajay / Tripathi, Madhavi / Vishnu, Venugopalan Y / Rajan, Roopa / Singh, Mamta B / Bhatia, Rohit / Srivastava, M V P / Gupta, Anu

    Annals of Indian Academy of Neurology

    2023  Volume 26, Issue 5, Page(s) 819–822

    Language English
    Publishing date 2023-10-13
    Publishing country India
    Document type Journal Article
    ZDB-ID 2240174-X
    ISSN 1998-3549 ; 0972-2327
    ISSN (online) 1998-3549
    ISSN 0972-2327
    DOI 10.4103/aian.aian_164_23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Changes in Cardiac Structure and Function Before and After Renal Transplantation: A Longitudinal Study.

    Jhinger, Manpreet Kaur / Sohal, Preet Mohinder / Makkar, Vikas / Tondon, Rohit / Wander, Gurpreet Singh / Sandhu, Jasvinder Singh

    Transplantation proceedings

    2021  Volume 53, Issue 3, Page(s) 1014–1018

    Abstract: Background: End-stage renal disease is a major risk factor for cardiovascular disease. Kidney transplantation (KT) may lead to reversal of these cardiac changes.: Methods: Echocardiographic changes in cardiac structure and function were recorded in ... ...

    Abstract Background: End-stage renal disease is a major risk factor for cardiovascular disease. Kidney transplantation (KT) may lead to reversal of these cardiac changes.
    Methods: Echocardiographic changes in cardiac structure and function were recorded in 30 patients with end-stage renal disease before KT, and 3 months and 6 months after KT. Patients with ischemic heart disease and valvular heart disease were not included.
    Results: Thirty patients with a mean age of 34±12 years were studied, and 28 (93%) were male. Mean duration of hemodialysis (none on peritoneal dialysis) was 9.18±8.39 months. There was significant improvement in echocardiographic parameter of cardiac morphology and the cardiac systolic and diastolic functions after KT.
    Conclusions: This longitudinal prospective study found significant regression of left ventricular hypertrophy within 6 months after renal transplant. There was also an improvement in ventricular functions on echocardiography. The improvement in hemoglobin shows linear correlation with reduction in left ventricular dimension and improvement in left ventricular functions.
    MeSH term(s) Adult ; Echocardiography ; Female ; Humans ; Hypertrophy, Left Ventricular/etiology ; Hypertrophy, Left Ventricular/pathology ; Kidney Transplantation ; Longitudinal Studies ; Male ; Middle Aged ; Prospective Studies ; Treatment Outcome ; Ventricular Function, Left/physiology
    Language English
    Publishing date 2021-02-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 82046-5
    ISSN 1873-2623 ; 0041-1345
    ISSN (online) 1873-2623
    ISSN 0041-1345
    DOI 10.1016/j.transproceed.2021.01.026
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  3. Article ; Online: Cricoid Ossification Mimicking an Esophageal Foreign Body

    Rohit Bhardwaj / Isha Preet Tuli / Mohamed Shareef PK / Ankur Gupta / Saurabh Makkar

    Dubai Medical Journal, Pp 1-

    A Victim of Overdiagnosis

    2021  Volume 4

    Abstract: Laryngeal cartilages undergo ossification, usually after the third decade of life. Variations exist in the extent and age of onset of ossification. Radiologically, these ossified cartilages may mimic an aerodigestive tract foreign body. We present an ... ...

    Abstract Laryngeal cartilages undergo ossification, usually after the third decade of life. Variations exist in the extent and age of onset of ossification. Radiologically, these ossified cartilages may mimic an aerodigestive tract foreign body. We present an unusual case where the ossified cricoid cartilage masqueraded as a fish bone in the aerodigestive tract. A 48-year-old male patient presented to us with a foreign body sensation and throat pain after consuming fish. We found no fish bone on endoscopic laryngopharyngeal assessment but noted a linear opacity against the C-6 vertebral body in the aerodigestive tract on a lateral X-ray film of the neck. Rigid esophagoscopy also did not reveal any foreign object, but a computed tomography (CT) scan showed a linear hyperdensity in the wall of the aerodigestive tract, against the C-6 vertebral body, due to linear ossification in the midline of the cricoid lamina posteriorly. The patient’s symptoms improved within 1 week of anti-reflux medications, and he remains asymptomatic. It is possible to encounter such rare cases of cartilage ossification while dealing with foreign body aerodigestive tract in adult patients in clinical practice. Proper assessment using CT scan prevents unnecessary procedures and anxiety to the patient.
    Keywords aerodigestive tract ; cricoid cartilage ossification ; esophagoscopy ; foreign body ; laryngeal cartilage ; Medicine ; R
    Subject code 616
    Language English
    Publishing date 2021-03-01T00:00:00Z
    Publisher Karger Publishers
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article: Expanding Mad Hatter's Shakes: Peripheral Nerve Hyperexcitability Syndrome with Artefactual-Looking Lung Lesions.

    Agarwal, Ayush / Makkar, Ayush M / Vishnu, Venugopalan Y / Gupta, Anu / Rajan, Roopa / Singh, Mamta B / Bhatia, Rohit / Srivastava, M V Padma

    Annals of Indian Academy of Neurology

    2020  Volume 24, Issue 6, Page(s) 993–994

    Language English
    Publishing date 2020-10-07
    Publishing country India
    Document type Journal Article
    ZDB-ID 2240174-X
    ISSN 1998-3549 ; 0972-2327
    ISSN (online) 1998-3549
    ISSN 0972-2327
    DOI 10.4103/aian.AIAN_727_20
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  5. Article: Deep Neck Space Infections: Current Trends and Intricacies of Management?

    Bhardwaj, Rohit / Makkar, Saurabh / Gupta, Ankur / Khandelwal, Kirti / Nathan, Karthika / Basu, Chirayata / Palaniyappan, Gowtham

    Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India

    2020  Volume 74, Issue Suppl 2, Page(s) 2344–2349

    Abstract: This study aims to describe the current epidemiological and etiological trends for deep neck space infections (DNIs) with an objective to understand the intricacies of their management. In this retrospective analytical study records of 52 patients with ... ...

    Abstract This study aims to describe the current epidemiological and etiological trends for deep neck space infections (DNIs) with an objective to understand the intricacies of their management. In this retrospective analytical study records of 52 patients with DNIs were reviewed. Patients having superficial abscess, peritonsillar abscess and abscess due to trauma/surgical procedure were excluded. Various epidemiological and etiological parameters (Demography, site, presentation, etiology, association with co-morbidities, bacteriology) and management guidelines (need for surgical interventions for DNIs and airway management, hospital stay duration, treatment outcome and complications) were reviewed and analyzed. Study recorded preponderance of DNIs in males (male:female = 1.6:1) and in younger generation (50% of patients presenting in first 2 decades). Commonest etiology being odontogenic infections (38.46%) followed by URTIs and tonsillopharyngitis (19.23%). Submandibular space involvement was noted in 42.3% cases followed by parapharyngeal space involvement in 21.15%. Nearly 55% cases of submandibular space involvement were because of odontogenic causes. 69.23% culture specimens reported no growth. 61.53% patients were diagnosed with anaemia. Up to 80% required open surgical drainage. All received broad spectrum antibiotics as a starting regime. No severe complications were recorded. Understanding the current epidemiological and etiological trends can help in early and definitive diagnosis of DNIs. Empirical starting treatment regime including broad spectrum antibiotics (till sensitivity pattern is availed) and maintaining low threshold for required surgical intervention are required to manage DNIs satisfactorily. Selected cases should be given conservative trials with close monitoring.
    Language English
    Publishing date 2020-09-28
    Publishing country India
    Document type Journal Article
    ZDB-ID 1471137-0
    ISSN 0973-7707 ; 2231-3796 ; 0019-5421
    ISSN (online) 0973-7707
    ISSN 2231-3796 ; 0019-5421
    DOI 10.1007/s12070-020-02174-4
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5300: Show issues Location:
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  6. Article: Colonoscopic perforation in inflammatory bowel disease.

    Makkar, Rohit / Bo, Shen

    Gastroenterology & hepatology

    2014  Volume 9, Issue 9, Page(s) 573–583

    Abstract: Colonoscopy has become the diagnostic and therapeutic modality of choice in patients with inflammatory bowel disease (IBD) by allowing for the assessment of disease extent and activity; the distinction between ulcerative colitis, Crohn's disease, and ... ...

    Abstract Colonoscopy has become the diagnostic and therapeutic modality of choice in patients with inflammatory bowel disease (IBD) by allowing for the assessment of disease extent and activity; the distinction between ulcerative colitis, Crohn's disease, and other differential diagnoses; the surveillance of dysplasia; and the delivery of treatment (eg, stricture dilation). Colonoscopy-associated perforation is a dreaded complication associated with significant mortality and morbidity. Understanding and mitigating the risks of perforation in patients with IBD has become an important issue with the increasing use of immunomodulators and biologic agents. Studies have shown that patients with IBD are at a higher risk for perforation from diagnostic or therapeutic endos-copy than individuals in the general population. Reported risk factors associated with colonoscopic perforation include female sex, advanced age, severe colitis, use of corticosteroids, presence of multiple comorbidities, and stricture dilation. Disease-, tech-nique-, and endoscopist-associated risk factors for perforation can be stratified and modified. This review, based on current available literature and the authors' expertise, should shed some light on the proper management of this challenging disease phenotype.
    Language English
    Publishing date 2014-03-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2386402-3
    ISSN 1554-7914
    ISSN 1554-7914
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6543: Show issues Location:
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  7. Article ; Online: Images in clinical medicine. Barium aspiration.

    Albeldawi, Mazen / Makkar, Rohit

    The New England journal of medicine

    2012  Volume 366, Issue 11, Page(s) 1038

    MeSH term(s) Aged ; Barium Sulfate/adverse effects ; Bronchography ; Fatal Outcome ; Humans ; Male ; Pneumonia, Aspiration/complications ; Pneumonia, Aspiration/diagnostic imaging ; Respiratory Insufficiency/etiology
    Chemical Substances Barium Sulfate (25BB7EKE2E)
    Language English
    Publishing date 2012-03-15
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMicm1108468
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  8. Article: What are the caveats to using sodium phosphate agents for bowel preparation?

    Makkar, Rohit / Shen, Bo

    Cleveland Clinic journal of medicine

    2008  Volume 75, Issue 3, Page(s) 173–176

    MeSH term(s) Cathartics/administration & dosage ; Cathartics/adverse effects ; Cathartics/pharmacology ; Enema/methods ; Humans ; Phosphates/administration & dosage ; Phosphates/adverse effects ; Phosphates/pharmacology ; Polyethylene Glycols/administration & dosage ; Polyethylene Glycols/adverse effects ; Polyethylene Glycols/pharmacology ; Water-Electrolyte Imbalance/chemically induced
    Chemical Substances Cathartics ; Phosphates ; Polyethylene Glycols (3WJQ0SDW1A) ; sodium phosphate (SE337SVY37)
    Language English
    Publishing date 2008-04-01
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 639116-3
    ISSN 0891-1150
    ISSN 0891-1150
    DOI 10.3949/ccjm.75.3.173
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    Ua VI Zs.212: Show issues Location:
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  9. Article ; Online: Clinical utility of retrograde terminal ileum intubation in the evaluation of chronic non-bloody diarrhea.

    Makkar, Rohit / Lopez, Rocio / Shen, Bo

    Journal of digestive diseases

    2013  Volume 14, Issue 10, Page(s) 536–542

    Abstract: Objective: The aims of this study were to investigate the frequency and factors involved in the terminal ileum intubation of patients with chronic, non-bloody diarrhea and to compare diagnostic yields of colonoscopy and ileocolonoscopy.: Methods: The ...

    Abstract Objective: The aims of this study were to investigate the frequency and factors involved in the terminal ileum intubation of patients with chronic, non-bloody diarrhea and to compare diagnostic yields of colonoscopy and ileocolonoscopy.
    Methods: The medical records of 945 patients undergoing colonoscopy for chronic, non-bloody diarrhea were reviewed. Findings of microscopic colitis, Clostridium difficile colitis, celiac disease, inflammatory bowel disease or tropical sprue were considered as definitive causes of diarrhea.
    Results: A total of 689 patients met the diagnosis of chronic, non-bloody diarrhea, in which 370 (53.7%) underwent ileocolonoscopy. Specific histological diagnosis could explain the patient's symptoms in 107 (15.5%) patients. The diagnostic yield were 15.0% in the colonoscopy-only group, 16.9% in the ileocolonoscopy without biopsy group, and 15.5% in the ileocolonoscopy with biopsy group. Of the 19 patients with an abnormal terminal ileal biopsy, six (31.6%) had an otherwise normal colonic appearance which would have been diagnosed as normal if the ileum had not been reached and biopsied. In those with Crohn's disease (n = 7), five had ileocolitis and two had colitis only. A multivariate analysis showed that age of the patients and otherwise normal gross endoscopic results to be the only factors associated with a lower likelihood of ileal intubation by endoscopists.
    Conclusions: The ileal intubation rate was 53.7% in our patients with chronic, non-bloody diarrhea. Diagnostic yield of ileocolonoscopy with biopsy in US patients with chronic, non-bloody diarrhea appeared to be low, if the colon side was normal on endoscopy. But this may provide supportive evidence in patients diagnosed with ileocolonic Crohn's disease.
    MeSH term(s) Adult ; Aged ; Biopsy ; Case-Control Studies ; Celiac Disease/complications ; Celiac Disease/diagnosis ; Chronic Disease ; Colitis/complications ; Colitis/diagnosis ; Colon/pathology ; Colonoscopy/methods ; Crohn Disease/complications ; Crohn Disease/diagnosis ; Diarrhea/etiology ; Diarrhea/pathology ; Female ; Humans ; Ileum/pathology ; Inflammatory Bowel Diseases/complications ; Inflammatory Bowel Diseases/diagnosis ; Intubation, Gastrointestinal/methods ; Intubation, Gastrointestinal/utilization ; Male ; Middle Aged
    Language English
    Publishing date 2013-10
    Publishing country Australia
    Document type Comparative Study ; Journal Article
    ZDB-ID 2317117-0
    ISSN 1751-2980 ; 1751-2972
    ISSN (online) 1751-2980
    ISSN 1751-2972
    DOI 10.1111/1751-2980.12082
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  10. Article ; Online: Sessile serrated polyps: cancer risk and appropriate surveillance.

    Makkar, Rohit / Pai, Rish K / Burke, Carol A

    Cleveland Clinic journal of medicine

    2012  Volume 79, Issue 12, Page(s) 865–871

    Abstract: Sessile serrated polyps are a recently recognized type of neoplastic polyp that develops along a molecular pathway different from that of conventional adenomas. While the clinical significance of the serrated pathway to colorectal cancer is clear, ... ...

    Abstract Sessile serrated polyps are a recently recognized type of neoplastic polyp that develops along a molecular pathway different from that of conventional adenomas. While the clinical significance of the serrated pathway to colorectal cancer is clear, further study is needed to understand a patient's lifetime colorectal cancer risk posed by serrated neoplasms and the optimal postpolypectomy surveillance interval.
    MeSH term(s) Colonoscopy ; Colorectal Neoplasms/diagnosis ; Colorectal Neoplasms/pathology ; Colorectal Neoplasms/prevention & control ; Humans ; Intestinal Polyps/pathology ; Intestinal Polyps/surgery ; Precancerous Conditions/pathology ; Precancerous Conditions/surgery ; Prognosis ; Risk ; Watchful Waiting
    Language English
    Publishing date 2012-12
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 639116-3
    ISSN 1939-2869 ; 0891-1150
    ISSN (online) 1939-2869
    ISSN 0891-1150
    DOI 10.3949/ccjm.79a.12034
    Database MEDical Literature Analysis and Retrieval System OnLINE

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