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  1. Article ; Online: Reply to: Inspiratory muscle training for COVID-19: Benefits appear promising but findings remain uncertain.

    Chen, Yusha / Liu, Xuefeng / Zhaohui, Tong

    Journal of medical virology

    2024  Volume 96, Issue 2, Page(s) e29441

    MeSH term(s) Humans ; COVID-19 ; Counseling ; Muscles
    Language English
    Publishing date 2024-02-02
    Publishing country United States
    Document type Letter
    ZDB-ID 752392-0
    ISSN 1096-9071 ; 0146-6615
    ISSN (online) 1096-9071
    ISSN 0146-6615
    DOI 10.1002/jmv.29441
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  2. Article ; Online: The efficacy and safety of patent Foramen Ovale Closure for Refractory Epilepsy (PFOC-RE): a prospectively randomized control trial of an innovative surgical therapy for refractory epilepsy patients with PFO of high-grade right-to-left shunt.

    Shuming, Ji / Hua, Li / Yusha, Tang / Lei, Chen

    BMC neurology

    2023  Volume 23, Issue 1, Page(s) 282

    Abstract: Background: A significant proportion of patients with epilepsy have an unknown etiology and lack effective targeted therapeutic drugs. Patent Foramen Ovale (PFO) induces hypoxia and microembolism, leading to cerebral neurological dysfunction and ... ...

    Abstract Background: A significant proportion of patients with epilepsy have an unknown etiology and lack effective targeted therapeutic drugs. Patent Foramen Ovale (PFO) induces hypoxia and microembolism, leading to cerebral neurological dysfunction and increased epilepsy risk. This study aims to assess the efficacy and safety of PFO closure for relieving epileptic seizures in patients with refractory epilepsy associated with PFO.
    Methods/design: Recruitment takes place at the West China Hospital of Sichuan University, China, for an open-label, randomized controlled clinical trial. The trial will include 110 patients with refractory epilepsy and PFO. Disease diagnoses will conform to the diagnostic criteria of the International League Against Epilepsy (ILAE) for refractory epilepsy and the American Society of Echocardiography (ASE) for PFO. Refractory epilepsy and high-grade right-to-left shunt (RLS) of the PFO will be further diagnosed using 24-hour video electroencephalogram and transthoracic echocardiography with contrast injection, respectively. Eligible participants require a secondary or higher volume of RLS.
    Trial registration: Chinese Clinical Trial Registry (ChiCTR2200065681). Registered on November 11, 2022.
    MeSH term(s) Humans ; Foramen Ovale, Patent/complications ; Foramen Ovale, Patent/surgery ; Drug Resistant Epilepsy/surgery ; Echocardiography ; Brain Diseases/complications ; Injections ; Treatment Outcome
    Language English
    Publishing date 2023-07-27
    Publishing country England
    Document type Randomized Controlled Trial ; Journal Article
    ZDB-ID 2041347-6
    ISSN 1471-2377 ; 1471-2377
    ISSN (online) 1471-2377
    ISSN 1471-2377
    DOI 10.1186/s12883-023-03317-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Epidermolytic ichthyosis caused by KRT10 parental cutaneous-gonadal mosaicism: a call for prospective genetic diagnosis.

    Song, Deyu / Zhang, Fang / Chen, Yusha / Li, Zhongtao / Wang, Sheng

    International journal of dermatology

    2023  Volume 62, Issue 11, Page(s) e583–e585

    Language English
    Publishing date 2023-09-12
    Publishing country England
    Document type Letter
    ZDB-ID 412254-9
    ISSN 1365-4632 ; 0011-9059 ; 1461-1244
    ISSN (online) 1365-4632
    ISSN 0011-9059 ; 1461-1244
    DOI 10.1111/ijd.16841
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  4. Article ; Online: One recurrent heterozygous mutation of the PLCD1 gene in a Chinese family with hereditary leukonychia: A case report and genotype-phenotype correlation analysis.

    Zhang, Fang / Chen, Yusha / Song, Deyu / Wang, Sheng

    The Journal of dermatology

    2023  Volume 50, Issue 8, Page(s) e230–e231

    MeSH term(s) Humans ; East Asian People ; Mutation ; Heterozygote ; Nail Diseases/genetics ; Nails, Malformed/diagnosis ; Nails, Malformed/genetics ; Genetic Association Studies ; Phenotype ; Genotype ; Pedigree ; Phospholipase C delta/genetics
    Chemical Substances PLCD1 protein, human (EC 3.1.4.11) ; Phospholipase C delta (EC 3.1.4.11)
    Language English
    Publishing date 2023-02-16
    Publishing country England
    Document type Case Reports ; Letter
    ZDB-ID 800103-0
    ISSN 1346-8138 ; 0385-2407
    ISSN (online) 1346-8138
    ISSN 0385-2407
    DOI 10.1111/1346-8138.16753
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  5. Article ; Online: Can inspiratory muscle training benefit patients with COVID-19? A systematic review and meta-analysis.

    Chen, Yusha / Liu, Xuefeng / Tong, Zhaohui

    Journal of medical virology

    2023  Volume 95, Issue 8, Page(s) e28956

    Abstract: The possible benefits of inspiratory muscle training (IMT) on mechanical and clinical outcomes in patients with Coronavirus disease-2019 (COVID-19) remain controversial. We conducted a meta-analysis to evaluate the effect of IMT in the rehabilitation ... ...

    Abstract The possible benefits of inspiratory muscle training (IMT) on mechanical and clinical outcomes in patients with Coronavirus disease-2019 (COVID-19) remain controversial. We conducted a meta-analysis to evaluate the effect of IMT in the rehabilitation strategy of patients with COVID-19. The Pubmed, Embase, Web of Science (WOS), and Cochrane Central Register of Controlled Trials (CENTRAL) were searched to identify trials evaluating the efficacy of IMT in the treatment of patients with COVID-19. The primary outcome included change from baseline of VO
    MeSH term(s) Humans ; Quality of Life ; Breathing Exercises ; COVID-19/therapy ; Respiratory Therapy ; Muscles
    Language English
    Publishing date 2023-07-28
    Publishing country United States
    Document type Meta-Analysis ; Systematic Review ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 752392-0
    ISSN 1096-9071 ; 0146-6615
    ISSN (online) 1096-9071
    ISSN 0146-6615
    DOI 10.1002/jmv.28956
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  6. Article ; Online: Formation and Transformation of CdS Clusters during the Prenucleation Stage and in a Dilute Dispersion at Room Temperature.

    Xu, Rongkuan / Wang, Zhe / Yang, Yusha / Gu, Cheng / Luan, Chaoran / Wang, Shanling / Chen, Xiaoqin / Yu, Kui

    Nano letters

    2024  Volume 24, Issue 4, Page(s) 1294–1302

    Abstract: The formation and transformation of colloidal semiconductor clusters remain poorly understood. With CdS as a model system, we show that, in the reaction of cadmium myristate (Cd(MA) ...

    Abstract The formation and transformation of colloidal semiconductor clusters remain poorly understood. With CdS as a model system, we show that, in the reaction of cadmium myristate (Cd(MA)
    Language English
    Publishing date 2024-01-17
    Publishing country United States
    Document type Journal Article
    ISSN 1530-6992
    ISSN (online) 1530-6992
    DOI 10.1021/acs.nanolett.3c04287
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Correlation between morphological parameters and dosimetric parameters of the heart and spinal cord in the intermediate- and advanced-stage esophageal cancer.

    Zhao, Wenjuan / Lan, Linzhen / Xu, Bichun / Chen, Di / Zeng, Yusha / Guo, Feibao / Zhang, Huojun

    Cancer reports (Hoboken, N.J.)

    2024  Volume 7, Issue 3, Page(s) e2015

    Abstract: Background: Radiation therapy plays a pivotal role as the primary adjuvant treatment for esophageal cancer (EPC), emphasizing the critical importance of carefully balancing radiation doses to the target area and organs at risk in the radiotherapeutic ... ...

    Abstract Background: Radiation therapy plays a pivotal role as the primary adjuvant treatment for esophageal cancer (EPC), emphasizing the critical importance of carefully balancing radiation doses to the target area and organs at risk in the radiotherapeutic management of esophageal cancer.
    Aims: This study aimed to explore the correlation between morphological parameters and dosimetric parameters of the heart and spinal cord in intermediate- and advanced-stage esophagus cancer to provide a reference for clinical treatment.
    Methods and results: A total of 105 patients with intermediate- and advanced-stage EPC, who received treatment in our hospital from 2019 to 2021, were included. The morphological parameters were calculated by imaging. Intensity-modulated radiation therapy plan was executed at Raystation4.7. The PTV-G stood for the externally expanded planning target volume (PTV) of the gross tumor volume (GTV) and PTV-C for the externally expanded volume of the clinical target volume (CTV). The prescription dose of PTV-G and PTV-C was set as 60Gy/30F and 54Gy/30F, respectively. The linear regression model was used to analyze the correlation between morphologic parameters of EPC and dosimetric parameters of the heart and spinal cord. In 105 cases, the total lung length was correlated with the spinal cord maximum dose (D
    Conclusions: Combined with the unsegmented tumor and different locations, the organ at risk dose was comprehensively considered.
    MeSH term(s) Humans ; Radiotherapy Dosage ; Radiotherapy Planning, Computer-Assisted ; Radiotherapy, Intensity-Modulated/methods ; Esophageal Neoplasms/radiotherapy ; Esophageal Neoplasms/pathology ; Spinal Cord/diagnostic imaging ; Spinal Cord/pathology
    Language English
    Publishing date 2024-03-15
    Publishing country United States
    Document type Journal Article
    ISSN 2573-8348
    ISSN (online) 2573-8348
    DOI 10.1002/cnr2.2015
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  8. Article ; Online: Teaching NeuroImage: A 41-Year-Old Woman Presented With Excessive Sweating of Contralateral Face and Extremity.

    Peng, Anjiao / Tang, Yusha / Song, Tingting / Chen, Lei

    Neurology

    2021  Volume 97, Issue 24, Page(s) e2429–e2430

    MeSH term(s) Adult ; Extremities ; Face ; Female ; Head ; Humans ; Hyperhidrosis/etiology ; Sweating
    Language English
    Publishing date 2021-08-16
    Publishing country United States
    Document type Case Reports ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 207147-2
    ISSN 1526-632X ; 0028-3878
    ISSN (online) 1526-632X
    ISSN 0028-3878
    DOI 10.1212/WNL.0000000000012666
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  9. Article ; Online: Evaluation of human acellular amniotic membrane for promoting anterior auricle reconstruction.

    Chen, Yusha / Lyu, Ling / Xue, Siliang

    Experimental dermatology

    2021  Volume 31, Issue 5, Page(s) 823–824

    MeSH term(s) Amnion/surgery ; Ear, External/surgery ; Humans ; Reconstructive Surgical Procedures
    Language English
    Publishing date 2021-12-07
    Publishing country Denmark
    Document type Letter
    ZDB-ID 1130936-2
    ISSN 1600-0625 ; 0906-6705
    ISSN (online) 1600-0625
    ISSN 0906-6705
    DOI 10.1111/exd.14508
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  10. Article ; Online: Mesenchymal Stem Cells in Radiation-Induced Pulmonary Fibrosis: Future Prospects.

    Chen, Yusha / Liu, Xuefeng / Tong, Zhaohui

    Cells

    2022  Volume 12, Issue 1

    Abstract: Radiation-induced pulmonary fibrosis (RIPF) is a general and fatal side effect of radiotherapy, while the pathogenesis has not been entirely understood yet. By now, there is still no effective clinical intervention available for treatment of RIPF. Recent ...

    Abstract Radiation-induced pulmonary fibrosis (RIPF) is a general and fatal side effect of radiotherapy, while the pathogenesis has not been entirely understood yet. By now, there is still no effective clinical intervention available for treatment of RIPF. Recent studies revealed mesenchymal stromal cells (MSCs) as a promising therapy treatment due to their homing and differentiation ability, paracrine effects, immunomodulatory effects, and MSCs-derived exosomes. Nevertheless, problems and challenges in applying MSCs still need to be taken seriously. Herein, we reviewed the mechanisms and challenges in the applications of MSCs in treating RIPF.
    MeSH term(s) Humans ; Pulmonary Fibrosis/pathology ; Lung/pathology ; Lung Injury/pathology ; Radiation Injuries/therapy ; Radiation Injuries/complications ; Mesenchymal Stem Cells
    Language English
    Publishing date 2022-12-20
    Publishing country Switzerland
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2661518-6
    ISSN 2073-4409 ; 2073-4409
    ISSN (online) 2073-4409
    ISSN 2073-4409
    DOI 10.3390/cells12010006
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