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  1. Article ; Online: Bacterial Contamination of Surfaces in Transcranial Magnetic Stimulation and Electroconvulsive Therapy: Do We Have Hygiene Problems in Interventional Psychiatry?

    Burri, Sarah / Mutschler, Jochen / Gutzeit, Andreas / Müller, Thomas

    The journal of ECT

    2023  Volume 40, Issue 1, Page(s) e4–e5

    MeSH term(s) Humans ; Electroconvulsive Therapy ; Transcranial Magnetic Stimulation
    Language English
    Publishing date 2023-12-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1426385-3
    ISSN 1533-4112 ; 1095-0680
    ISSN (online) 1533-4112
    ISSN 1095-0680
    DOI 10.1097/YCT.0000000000000969
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Differenzialdiagnose seltener MRT Befunde des weiblichen Beckens: einmal gesehen, nie mehr vergessen.

    Hecht, Stefan / Gutzeit, Andreas / Forstner, Rosemarie

    RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin

    2023  

    Title translation Rare MRI findings of the female pelvis - once seen, never forgotten.
    Language German
    Publishing date 2023-05-24
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 554830-5
    ISSN 1438-9010 ; 0340-1618 ; 0936-6652 ; 1433-5972 ; 1438-9029
    ISSN (online) 1438-9010
    ISSN 0340-1618 ; 0936-6652 ; 1433-5972 ; 1438-9029
    DOI 10.1055/a-2077-1598
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book ; Thesis: Produktion von vascular endothelial growth factor (VEGF) durch mononukleäre periphere Entzündungszellen (PBMC) bei Patienten mit Morbus Crohn

    Gutzeit, Andreas

    2000  

    Author's details vorgelegt von Andreas Gutzeit
    Language German
    Size 69 Bl. : graph. Darst.
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Bochum, Univ., Diss., 2001
    HBZ-ID HT013052723
    Database Catalogue ZB MED Medicine, Health

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  4. Article: Differenzialdiagnose seltener MRT Befunde des weiblichen Beckens: einmal gesehen, nie mehr vergessen

    Hecht, Stefan / Gutzeit, Andreas / Forstner, Rosemarie

    RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren

    2023  

    Language German
    Publishing date 2023-05-24
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 554830-5
    ISSN 1438-9010 ; 1438-9029 ; 0340-1618 ; 0936-6652 ; 1433-5972
    ISSN (online) 1438-9010
    ISSN 1438-9029 ; 0340-1618 ; 0936-6652 ; 1433-5972
    DOI 10.1055/a-2077-1598
    Database Thieme publisher's database

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  5. Article: Adulter Morbus Still (AOSD)

    Giordano, Anna / Hake, Lisanne / Gutzeit, Thorsten / Rose, Christian / Kleinheinz, Andreas

    Derm

    2023  Volume 29, Issue 2, Page(s) 153

    Language German
    Document type Article
    ZDB-ID 1315453-9
    ISSN 0949-7633
    Database Current Contents Medicine

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  6. Article: Paraneoplastisches Anti-p200-Pemphigoid, am ehesten bei einer intraduktal papillär-muzinösen Neoplasie im Pankreaskopf

    Giordano, Anna / Massoun, Valerie / Gutzeit, Thorsten / Rose, Christian / Kleinheinz, Andreas

    Derm

    2023  Volume 29, Issue 3, Page(s) 319

    Language German
    Document type Article
    ZDB-ID 1315453-9
    ISSN 0949-7633
    Database Current Contents Medicine

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  7. Article ; Online: Pregabalin use in forensic hospitals and prisons in German speaking countries-a survey study of physicians.

    Novotny, Michal / Bulla, Jan / Hubl, Daniela / Fischer, Sebastian Karl Maximilian / Grosshans, Martin / Gutzeit, Andreas / Bilke-Hentsch, Oliver / Seifritz, Erich / Mutschler, Jochen

    Frontiers in public health

    2024  Volume 11, Page(s) 1309654

    Abstract: Background: Pregabalin is a gamma-aminobutyric acid (GABA) analog that was approved in the EU in 2004 for the treatment of neuropathic pain, generalized anxiety disorder and epilepsy. Since its introduction, pregabalin abuse and misuse has increased ... ...

    Abstract Background: Pregabalin is a gamma-aminobutyric acid (GABA) analog that was approved in the EU in 2004 for the treatment of neuropathic pain, generalized anxiety disorder and epilepsy. Since its introduction, pregabalin abuse and misuse has increased significantly. In Switzerland, clinical reports suggest that pregabalin misuse is common among patients in forensic hospitals and prisons. However, data on pregabalin use is scarce, especially in these settings. Therefore, we conducted a study to explore patterns of pregabalin use among prison and forensic patients.
    Methods: We used a questionnaire to survey physicians working in prison and forensic medicine in German-speaking countries. A total of 131 responses were received.
    Results: According to the physicians' subjective assessment, 82.5% of them had observed a recent increase in pregabalin use by their patients and 89.1% of them reported that their patients requested pregabalin without a clear medical indication. Patients misusing pregabalin in combination with other illicit substances were observed by 93.3% of the physicians surveyed. According to 73.5% of the physicians surveyed, they had already encountered patients on pregabalin doses of more than 600 mg/day (the maximum recommended daily dose); the highest dose reported was 4,200 mg/day. According to 85.0% of physicians surveyed, they have observed patients experiencing withdrawal symptoms from pregabalin, with the most commonly reported symptoms being displeasure and high aggression. Regarding the nationality of pregabalin-misusing patients, 58.3% of the interviewed physicians reported to be rather in contact with foreign patients, mainly from Northwest Africa (Maghreb). Only 45.0% of the surveyed physicians prescribe pregabalin. Among patients who developed behavioral problems while taking pregabalin, none of the physicians (0.0%) showed a tendency to continue pregabalin at the same dose; all respondents chose to reduce/substitute/discontinue.
    Conclusion: Our study has provided confirmatory evidence that the use of pregabalin presents a significant issue in forensic and prison medicine across German-speaking countries. Prescribing pregabalin in this field can compound use disorder problems and exacerbate challenges in daily life for those in forensic institutions or prisons. It is necessary that all physicians who prescribe pregabalin are clearly informed about the management (including the risks) of this drug.
    MeSH term(s) Humans ; Prisons ; Pregabalin/therapeutic use ; gamma-Aminobutyric Acid ; Hospitals ; Physicians
    Chemical Substances Pregabalin (55JG375S6M) ; gamma-Aminobutyric Acid (56-12-2)
    Language English
    Publishing date 2024-01-08
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2711781-9
    ISSN 2296-2565 ; 2296-2565
    ISSN (online) 2296-2565
    ISSN 2296-2565
    DOI 10.3389/fpubh.2023.1309654
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Serum Neurofilament light chain (NfL) levels in children with and without neurologic diseases.

    Geis, Tobias / Gutzeit, Svena / Fouzas, Sotiris / Ambrosch, Andreas / Benkert, Pascal / Kuhle, Jens / Wellmann, Sven

    European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society

    2023  Volume 45, Page(s) 9–13

    Abstract: Background/objective: Serum neurofilament light chain (sNfL) is a specific biomarker of neuronal damage. Elevated sNfL levels have been reported in numerous neurologic diseases in adults, whereas data on sNfL in the pediatric population are incomplete. ... ...

    Abstract Background/objective: Serum neurofilament light chain (sNfL) is a specific biomarker of neuronal damage. Elevated sNfL levels have been reported in numerous neurologic diseases in adults, whereas data on sNfL in the pediatric population are incomplete. The aim of this study was to investigate sNfL levels in children with various acute and chronic neurologic disorders and describe the age dependence of sNfL from infancy to adolescence.
    Methods: The total study cohort of this prospective cross-sectional study consisted of 222 children aged from 0 to 17 years. Patients' clinical data were reviewed and patients were assigned to the following groups: 101 (45.5%) controls, 34 (15.3%) febrile controls, 23 (10.4%) acute neurologic conditions (meningitis, facial nerve palsy, traumatic brain injury, or shunt dysfunction in hydrocephalus), 37 (16.7%) febrile seizures, 6 (2.7%) epileptic seizures, 18 (8.1%) chronic neurologic conditions (autism, cerebral palsy, inborn mitochondrial disorder, intracranial hypertension, spina bifida, or chromosomal abnormalities), and 3 (1.4%) severe systemic disease. sNfL levels were measured using a sensitive single-molecule array assay.
    Results: There were no significant differences in sNfL levels between controls, febrile controls, febrile seizures, epileptic seizures, acute neurologic conditions, and chronic neurologic conditions. In children with severe systemic disorders, by far the highest NfL levels were found with an sNfL of 429 pg/ml in a patient with neuroblastoma, 126 pg/ml in a patient with cranial nerve palsy and pharyngeal Burkitt's lymphoma, and 42 pg/ml in a child with renal transplant rejection. The relationship between sNfL and age could be described by a second order polynomial with an R
    Conclusions: In this study cohort, sNfL levels were not elevated in children with febrile or epileptic seizures, or various other neurologic diseases. Strikingly high sNfL levels were detected in children with oncologic disease or transplant rejection. A biphasic sNfL age-dependency was documented, with highest levels in infancy and late adolescence and the lowest levels in middle school age.
    MeSH term(s) Adult ; Adolescent ; Humans ; Child ; Child, Preschool ; Prospective Studies ; Cross-Sectional Studies ; Intermediate Filaments ; Biomarkers ; Seizures, Febrile ; Multiple Sclerosis
    Chemical Substances Biomarkers
    Language English
    Publishing date 2023-05-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 1397146-3
    ISSN 1532-2130 ; 1090-3798
    ISSN (online) 1532-2130
    ISSN 1090-3798
    DOI 10.1016/j.ejpn.2023.05.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: T2-weighted Dixon MRI of the spine: A feasibility study of quantitative vertebral bone marrow analysis.

    Donners, Ricardo / Hirschmann, Anna / Gutzeit, Andreas / Harder, Dorothee

    Diagnostic and interventional imaging

    2021  Volume 102, Issue 7-8, Page(s) 431–438

    Abstract: Purpose: To compare the measurements of fat fraction (FF) and in-phase vs. opposed-phase ratio between two-dimensional T2-weighted (T2W) spin-echo (SE) Dixon and three-dimensional (3D) T1-weighted (T1W) volume interpolated breath-hold examination (VIBE) ...

    Abstract Purpose: To compare the measurements of fat fraction (FF) and in-phase vs. opposed-phase ratio between two-dimensional T2-weighted (T2W) spin-echo (SE) Dixon and three-dimensional (3D) T1-weighted (T1W) volume interpolated breath-hold examination (VIBE) Dixon sequences in malignant vertebral lesions and normal vertebral bone marrow.
    Materials and methods: Thirty patients with focal vertebral malignancies (20 men, mean age, 67.3±9.4 [SD] years; age range: 41-84 years) and 30 patients without malignant spinal disease (11 men, mean age, 70.1±12.9 [SD]; age range: 53-93 years) were retrospectively included. Each patient underwent spine MRI at 1.5 Tesla including T2W SE and T1W VIBE 2-point Dixon sequences. Two readers independently performed 3D-volume of interest (VOI) and region of interest (ROI)-based FF and IO-ratio measurements of malignant lesions and normal vertebrae. Student t-test, Pearson correlation (r) test and two-way mixed model intraclass correlation coefficients (ICC) were used to compare measurements.
    Results: T2W SE and T1W VIBE mean FF and IO-ratio were significantly smaller in malignancy compared to normal marrow, but there were significant differences of paired measurement mean values between T2W SE and T1W VIBE Dixon parameters in malignant lesions T2W SE VOI FF=9%, T2W SE ROI FF=7%, T2W SE IO-ratio=4% vs. T1W VIBE VOI FF=11%, T1W VIBE ROI FF=9%, T1W VIBE IO-ratio=-2%, and in normal vertebrae T2W SE VOI FF=74%, T2W SE ROI FF=77%, T2W SE IO-ratio=51% vs. T1W VIBE VOI FF=67%, T1W VIBE ROI FF=73%, T1W VIBE IO-ratio=58% (each P comparing the paired T2W TSE and T1W VIBE parameter, respectively<0.001). There was excellent positive correlation between T2W SE and T1W VIBE-FF (r≥0.99) and VOI and ROI FF measurements for each sequence (r≥0.99). Inter-reader agreement was excellent for all measurements (ICC≥0.94 for all).
    Conclusion: Calculation of T2W SE Dixon derived FF is feasible and gave valid results that help discriminate between malignant vertebral lesions and normal vertebral bone marrow.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Bone Marrow/diagnostic imaging ; Feasibility Studies ; Humans ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Retrospective Studies ; Spine/diagnostic imaging
    Language English
    Publishing date 2021-02-19
    Publishing country France
    Document type Journal Article
    ZDB-ID 2648283-6
    ISSN 2211-5684 ; 2211-5684
    ISSN (online) 2211-5684
    ISSN 2211-5684
    DOI 10.1016/j.diii.2021.01.013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Klinik, Diagnostik und Differenzialdiagnostik von Fehlbildungen des weiblichen Genitaltrakts

    Prots, Iryna / Gutzeit, Andreas / Forstner, Rosemarie

    Radiologie up2date

    2021  Volume 21, Issue 04, Page(s) 329–348

    Keywords Uterusanomalie ; Vagina ; Fehlbildung ; Fertilität ; MRT ; uterine anomalies ; vagina ; malformation ; fertility ; MRI
    Language German
    Publishing date 2021-12-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2065319-0
    ISSN 1617-8300 ; 1616-0681
    ISSN (online) 1617-8300
    ISSN 1616-0681
    DOI 10.1055/a-1493-0487
    Database Thieme publisher's database

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