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Article: Soil health: A common focus for one health and planetary health interventions.

Montgomery, David R / Rabinowitz, Peter / Sipos, Yona / Wheat, Eli E

2024 Volume 18, Page(s) 100673

Abstract: Proponents of both the One Health and Planetary Health paradigms have acknowledged that current methods of agricultural food production are driving many environmental changes with negative human health consequences, including climate change, ... ...

Abstract	Proponents of both the One Health and Planetary Health paradigms have acknowledged that current methods of agricultural food production are driving many environmental changes with negative human health consequences, including climate change, deforestation, and the emergence of zoonotic disease and antimicrobial resistance. Currently, the training of human health, veterinary, and public health professionals typically does not include aspects of soil health. Much of the resultant discussion in One Health and Planetary Health circles regarding interventions to address the health impact of agricultural practices has focused on measures such as advocating for dietary change toward plant based diets and increasing food safety, biosecurity, disease surveillance and antimicrobial stewardship. A greater understanding of soil health and its relationship to agricultural practices could prove foundational to many of the problems that the One Health and Planetary Health perspectives aim to address, including antimicrobial resistance, zoonotic disease emergence, food security, and climate change. A consequent global focus on the health of soils offers a promise of specific opportunities for preventive interventions and a greater convergence between the One Health and Planetary Health approaches.
Language	English
Publishing date	2024-01-03
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	2834831-X
ISSN	2352-7714
ISSN	2352-7714
DOI	10.1016/j.onehlt.2023.100673
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Article ; Online: Seafloor incubation experiments at deep-sea hydrothermal vents reveal distinct biogeographic signatures of autotrophic communities.

Fullerton, Heather / Smith, Lindsey / Enriquez, Alejandra / Butterfield, David / Wheat, C Geoffrey / Moyer, Craig L

FEMS microbiology ecology

2024 Volume 100, Issue 2

Abstract: The discharge of hydrothermal vents on the seafloor provides energy sources for dynamic and productive ecosystems, which are supported by chemosynthetic microbial populations. These populations use the energy gained by oxidizing the reduced chemicals ... ...

Abstract	The discharge of hydrothermal vents on the seafloor provides energy sources for dynamic and productive ecosystems, which are supported by chemosynthetic microbial populations. These populations use the energy gained by oxidizing the reduced chemicals contained within the vent fluids to fix carbon and support multiple trophic levels. Hydrothermal discharge is ephemeral and chemical composition of such fluids varies over space and time, which can result in geographically distinct microbial communities. To investigate the foundational members of the community, microbial growth chambers were placed within the hydrothermal discharge at Axial Seamount (Juan de Fuca Ridge), Magic Mountain Seamount (Explorer Ridge), and Kama'ehuakanaloa Seamount (Hawai'i hotspot). Campylobacteria were identified within the nascent communities, but different amplicon sequence variants were present at Axial and Kama'ehuakanaloa Seamounts, indicating that geography in addition to the composition of the vent effluent influences microbial community development. Across these vent locations, dissolved iron concentration was the strongest driver of community structure. These results provide insights into nascent microbial community structure and shed light on the development of diverse lithotrophic communities at hydrothermal vents.
MeSH term(s)	Seawater/microbiology ; Biodiversity ; Hydrothermal Vents/microbiology ; Autotrophic Processes ; Microbiota ; Phylogeny
Language	English
Publishing date	2024-01-09
Publishing country	England
Document type	Journal Article ; Research Support, U.S. Gov't, Non-P.H.S. ; Research Support, Non-U.S. Gov't
ZDB-ID	283722-5
ISSN	1574-6941 ; 0168-6496
ISSN (online)	1574-6941
ISSN	0168-6496
DOI	10.1093/femsec/fiae001
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Article ; Online: Soil health

David R. Montgomery / Peter Rabinowitz / Yona Sipos / Eli E. Wheat

One Health, Vol 18, Iss , Pp 100673- (2024)

A common focus for one health and planetary health interventions

2024

Abstract	Proponents of both the One Health and Planetary Health paradigms have acknowledged that current methods of agricultural food production are driving many environmental changes with negative human health consequences, including climate change, deforestation, and the emergence of zoonotic disease and antimicrobial resistance. Currently, the training of human health, veterinary, and public health professionals typically does not include aspects of soil health. Much of the resultant discussion in One Health and Planetary Health circles regarding interventions to address the health impact of agricultural practices has focused on measures such as advocating for dietary change toward plant based diets and increasing food safety, biosecurity, disease surveillance and antimicrobial stewardship. A greater understanding of soil health and its relationship to agricultural practices could prove foundational to many of the problems that the One Health and Planetary Health perspectives aim to address, including antimicrobial resistance, zoonotic disease emergence, food security, and climate change. A consequent global focus on the health of soils offers a promise of specific opportunities for preventive interventions and a greater convergence between the One Health and Planetary Health approaches.
Keywords	One health ; Planetary health ; Soil health ; Soil ; Antimicrobial resistance ; Agriculture ; Medicine (General) ; R5-920
Language	English
Publishing date	2024-06-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: What can system dynamics learn from the public policy implementation literature?

Wheat, I David

Systems research and behavioral science

2010 Volume 27, Issue 4, Page(s) 425–442

Abstract: More often than not, system dynamics model-based public policy analysis is limited to testing parameter changes instead of designing and testing new stock-and-flow policy structures. That is problematic because improvements in behaviour require ... ...

Abstract	More often than not, system dynamics model-based public policy analysis is limited to testing parameter changes instead of designing and testing new stock-and-flow policy structures. That is problematic because improvements in behaviour require improvements in structure. This paper considers how the public policy implementation literature could improve the operational thinking skills required for designing policy structure for public sector models. A familiar model of a public health problem is used to illustrate the recommended approach. And an instructional training strategy is offered for teaching and learning to think operationally during the policy-design stage of modelling. Copyright © 2010 John Wiley & Sons, Ltd.
Keywords	covid19
Language	English
Publishing date	2010-07-15
Publishing country	England
Document type	Journal Article
ZDB-ID	1491223-5
ISSN	1099-1743 ; 1092-7026
ISSN (online)	1099-1743
ISSN	1092-7026
DOI	10.1002/sres.1039
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Book ; Online: (Appendix) Fluid chemistry and strontium isotope data for ODP Hole 168-1026B, supplementary data to: Butterfield, David A; Nelson, Bruce K; Wheat, C Geoffrey; Mottl, Michael J; Roe, Kevin K (2001): Evidence for basaltic Sr in midocean ridge-flank hydrothermal systems and implications for the global oceanic Sr isotope balance. Geochimica et Cosmochimica Acta, 65(22), 4141-4153

Butterfield, David A / Mottl, Michael J / Nelson, Bruce K / Roe, Kevin K / Wheat, C Geoffrey

2001

Abstract: Previous models and calculations of the global mass balance of Sr in the oceans have shown that the input of unradiogenic basaltic Sr from on-axis midocean ridge hydrothermal systems is much less than needed to balance the input of radiogenic Sr ... ...

Abstract	Previous models and calculations of the global mass balance of Sr in the oceans have shown that the input of unradiogenic basaltic Sr from on-axis midocean ridge hydrothermal systems is much less than needed to balance the input of radiogenic Sr delivered to the oceans by rivers. The implication is that either the oceans are far from steady state with respect to Sr isotope balance (and that the 87Sr/86Sr ratio of seawater is increasing at unprecedented rates) or that there is a significant missing source of basaltic Sr. It has long been recognized that off-axis hydrothermal fluxes might significantly affect the mass and isotopic balance of Sr and other elements in the oceans, but nearly all previous work has concluded that the 87Sr/86Sr ratio of pore fluids in ridge-flank hydrothermal areas is virtually indistinguishable from the seawater ratio or is dominated by authigenic carbonates. In contrast, we report here the 87Sr/86Sr ratios of warm springs, sediment pore fluids, and basement reservoir fluid with a clear basaltic signature from the eastern flank of the Juan de Fuca ridge (JFR). Fluids venting from Ocean Drilling Program Hole 1026B on the Juan de Fuca east flank have relatively stable Sr isotope and major element composition for the 3 yr following drilling. These results and similar results recently reported by Elderfield et al. (1999) indicate that low-temperature ridge-flank hydrothermal circulation has an important effect on the Sr isotope balance in the oceans. If published values for the other major sources of Sr input to the oceans (rivers and axial hydrothermal flux) are accurate, then the rate of increase of the 87Sr/86Sr ratio in seawater (~0.000054 per million years) can be accommodated if ridge flanks on a global scale deliver fluids to the ocean with delta (87Sr/86Sr)/heat ratios one third to one half of the ratio found in warm JFR basement fluids. Based on published Sr and O isotope signatures of calcite veins in the uppermost basaltic ocean crust, the average delta (87Sr/86Sr)/heat ratio of low-temperature fluids is in the range required to balance the oceanic Sr isotope budget. Although the 87Sr/86Sr ratios of the JFR flank fluids in this study overlap with fluid properties inferred from some calcite veins in the upper oceanic crust, the magnitudes of the delta (87Sr/86Sr)/heat ratios of nearly all of the JFR flank fluids are too large to be representative of the average global flank fluid flux; the same has been argued on the basis of the extremely high implied Mg flux.
Language	English
Dates of publication	2001-9999
Size	Online-Ressource
Publisher	PANGAEA - Data Publisher for Earth & Environmental Science
Publishing place	Bremen/Bremerhaven
Document type	Book ; Online
Note	This dataset is supplement to doi:10.1016/S0016-7037(01)00712-8
DOI	10.1594/PANGAEA.708425
Database	Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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Article ; Online: Learning from national implementation of the Veterans Affairs Clinical Resource Hub (CRH) program for improving access to care: protocol for a six year evaluation.

Rubenstein, Lisa V / Curtis, Idamay / Wheat, Chelle L / Grembowski, David E / Stockdale, Susan E / Kaboli, Peter J / Yoon, Jean / Felker, Bradford L / Reddy, Ashok S / Nelson, Karin M

BMC health services research

2023 Volume 23, Issue 1, Page(s) 790

Abstract: Background: The Veterans Affairs (VA) Clinical Resource Hub (CRH) program aims to improve patient access to care by implementing time-limited, regionally based primary or mental health staffing support to cover local staffing vacancies. VA's Office of ... ...

Abstract	Background: The Veterans Affairs (VA) Clinical Resource Hub (CRH) program aims to improve patient access to care by implementing time-limited, regionally based primary or mental health staffing support to cover local staffing vacancies. VA's Office of Primary Care (OPC) designed CRH to support more than 1000 geographically disparate VA outpatient sites, many of which are in rural areas, by providing virtual contingency clinical staffing for sites experiencing primary care and mental health staffing deficits. The subsequently funded CRH evaluation, carried out by the VA Primary Care Analytics Team (PCAT), partnered with CRH program leaders and evaluation stakeholders to develop a protocol for a six-year CRH evaluation. The objectives for developing the CRH evaluation protocol were to prospectively: 1) identify the outcomes CRH aimed to achieve, and the key program elements designed to achieve them; 2) specify evaluation designs and data collection approaches for assessing CRH progress and success; and 3) guide the activities of five geographically dispersed evaluation teams. Methods: The protocol documents a multi-method CRH program evaluation design with qualitative and quantitative elements. The evaluation's overall goal is to assess CRH's return on investment to the VA and Veterans at six years through synthesis of findings on program effectiveness. The evaluation includes both observational and quasi-experimental elements reflecting impacts at the national, regional, outpatient site, and patient levels. The protocol is based on program evaluation theory, implementation science frameworks, literature on contingency staffing, and iterative review and revision by both research and clinical operations partners. Discussion: Health systems increasingly seek to use data to guide management and decision-making for newly implemented clinical programs and policies. Approaches for planning evaluations to accomplish this goal, however, are not well-established. By publishing the protocol, we aim to increase the validity and usefulness of subsequent evaluation findings. We also aim to provide an example of a program evaluation protocol developed within a learning health systems partnership.
MeSH term(s)	Humans ; Veterans ; Data Collection ; Implementation Science ; Investments ; Health Services Accessibility
Language	English
Publishing date	2023-07-25
Publishing country	England
Document type	Journal Article
ZDB-ID	2050434-2
ISSN	1472-6963 ; 1472-6963
ISSN (online)	1472-6963
ISSN	1472-6963
DOI	10.1186/s12913-023-09799-5
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Article ; Online: Quantifying the hip-ankle synergy in short-term maximal cycling.

Burnie, Louise / Barratt, Paul / Davids, Keith / Worsfold, Paul / Wheat, Jon

Journal of biomechanics

2022 Volume 142, Page(s) 111268

Abstract: Simulation studies have demonstrated that the hip and ankle joints form a task-specific synergy during the downstroke in maximal cycling to enable the power produced by the hip extensor muscles to be transferred to the crank. The existence of the hip- ... ...

Abstract	Simulation studies have demonstrated that the hip and ankle joints form a task-specific synergy during the downstroke in maximal cycling to enable the power produced by the hip extensor muscles to be transferred to the crank. The existence of the hip-ankle synergy has not been investigated experimentally. Therefore, we sought to apply a modified vector coding technique to quantify the strength of the hip-ankle moment synergy in the downstroke during short-term maximal cycling at a pedalling rate of 135 rpm. Twelve track sprint cyclists performed 3 × 4 s seated sprints at 135 rpm, interspersed with 2 × 4 s seated sprints at 60 rpm on an isokinetic ergometer. Data from the 60 rpm sprints were not analysed in this study. Joint moments were calculated via inverse dynamics, using pedal forces and limb kinematics. The hip-ankle moment synergy was quantified using a modified vector coding method. Results showed, for 28.8% of the downstroke the hip and ankle moments were in-phase, demonstrating the hip and ankle joints tend to work in synergy in the downstroke, providing some support findings from simulation studies of cycling. At a pedalling rate of 135 rpm the hip-phase was most frequent (42.5%) significantly differing from the in- (P = 0.044), anti- (P < 0.001), and ankle-phases (P = 0.004), demonstrating hip-dominant action. We believe this method shows promise to answer research questions on the relative strength of the hip-ankle synergy between different cycling conditions (e.g., power output and pedalling rates).
MeSH term(s)	Ankle/physiology ; Ankle Joint/physiology ; Bicycling/physiology ; Biomechanical Phenomena ; Ergometry ; Hip Joint/physiology ; Knee Joint/physiology
Language	English
Publishing date	2022-08-24
Publishing country	United States
Document type	Journal Article
ZDB-ID	218076-5
ISSN	1873-2380 ; 0021-9290
ISSN (online)	1873-2380
ISSN	0021-9290
DOI	10.1016/j.jbiomech.2022.111268
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Article: Is a Depth Camera in Agreement with an Electromagnetic Tracking Device when Measuring Head Position?

Burchell, Vienna-Jaye / Arblaster, Gemma / Buckley, David / Wheat, Jonathan

The British and Irish orthoptic journal

2021 Volume 17, Issue 1, Page(s) 142–149

Abstract: Introduction: Clinicians typically observe and describe abnormal head postures (AHPs) and may also measure them. Depth cameras have been suggested as a reliable measurement device for measuring head position using face-tracking technology. This study ... ...

Abstract	Introduction: Clinicians typically observe and describe abnormal head postures (AHPs) and may also measure them. Depth cameras have been suggested as a reliable measurement device for measuring head position using face-tracking technology. This study compared a depth camera (Microsoft Kinect) to a gold standard electromagnetic tracking system (Polhemus device) to measure head position. Method: Twenty healthy volunteers (mean age 21 years) had their head position simultaneously recorded using the depth camera (Kinect) and the electromagnetic tracking system (Polhemus). Participants were asked to make 30-degree head movements into chin up, chin down, head turn and head tilt positions. The head movement made and the stability of the head at each position were recorded and analysed. Results: Compared to the electromagnetic tracking system (Polhemus), the depth camera (Kinect) always measured a smaller head movement. Measurements with the two devices were not statistically significantly different for turn right (P = 0.3955, p > 0.05), turn left (P = 0.4749, p > 0.05), tilt right (P = 0.7086, p > 0.05) and tilt left (P = 0.4091, p > 0.05) head movements. However, the smaller depth camera measurement of chin up and chin down head movements were statistically significant, chin up (P = 0.0001, p < 0.01) and chin down (P = 0.0005, p < 0.001). At each eccentric position, the depth camera (Kinect) recordings were more variable than the electromagnetic tracking system (Polhemus). Conclusions: Compared to the electromagnetic tracking system (Polhemus), the depth camera (Kinect) was comparable for measuring head turns and tilts but was less accurate at measuring chin up and chin down head positions. Further research is needed before the depth cameras are considered for clinical recordings of head position.
Language	English
Publishing date	2021-11-15
Publishing country	England
Document type	Journal Article
ZDB-ID	2163627-8
ISSN	1743-9868
ISSN	1743-9868
DOI	10.22599/bioj.227
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Article ; Online: Economic cost-utility analysis of stage-directed gastric cancer treatment.

Powell, Arfon G / Wheat, Jennifer R / Eley, Catherine / Robinson, David / Roberts, Stuart A / Lewis, Wyn

BJS open

2022 Volume 5, Issue 6

Abstract: Background: Gastric cancer (GC) treatment levies substantial financial burden on health services. Potentially curative surgery with or without chemotherapy is offered to patients with locoregional disease. This study aimed to examine treatment costs ... ...

Abstract	Background: Gastric cancer (GC) treatment levies substantial financial burden on health services. Potentially curative surgery with or without chemotherapy is offered to patients with locoregional disease. This study aimed to examine treatment costs related to life-years gained in patients having potentially curative treatment (gastrectomy) and those receiving best supportive care (BSC). Methods: Some 398 consecutive patients with GC were classified according to treatment modality (116 BSC, 282 gastrectomy). Cost calculations for 1 year's treatment from referral were made according to network diagnostic, staging and treatment algorithms. Primary outcome was overall survival (OS). Results: GC median survival after BSC was 8 months, costing €5413, compared with gastrectomy median survival of 34 months, costing €22 753 for 1 year's treatment: cost per life-year gained €9319. Cost incurred for stage I GC was €22 434, stage II €23 498, stage III €22 445, and stage IV €22 032. Based on these values, the cost per quality adjusted life-year (QALY) for BSC for stage I GC was -€8335 stage II -€8952, stage III -€11 317, and stage IV -€25 669. Conclusion: Potentially curative treatment that included gastrectomy improved OS four-fold compared with BSC and was cost-effective at national thresholds of readiness to pay per QALY.
MeSH term(s)	Cost-Benefit Analysis ; Humans ; Quality-Adjusted Life Years ; Stomach Neoplasms/surgery
Language	English
Publishing date	2022-01-12
Publishing country	England
Document type	Journal Article
ISSN	2474-9842
ISSN (online)	2474-9842
DOI	10.1093/bjsopen/zrab129
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Article ; Online: Exacerbation of Renal, Cardiovascular, and Respiratory Outcomes Associated with Changes in Climate.

Baraghoshi, David / Niswander, Cameron / Strand, Matthew / Wheat, Stefan / Ramstetter, Julie / Stoll, Nicholas / Fox, Jacob / James, Katherine A

The Yale journal of biology and medicine

2023 Volume 96, Issue 2, Page(s) 159–169

Abstract: Exposure to environmental variables including declining air quality and increasing temperatures can exert detrimental effects on human health including acute exacerbations of chronic diseases. We aim to investigate the association between these exposures ...

Abstract	Exposure to environmental variables including declining air quality and increasing temperatures can exert detrimental effects on human health including acute exacerbations of chronic diseases. We aim to investigate the association between these exposures and acute health outcomes in a rural community in Colorado. Meteorological and adult emergency department visit data were retrospectively collected (2013-2017); for asthma outcomes, additional data were available (2003-2017). Daily environmental exposure data included PM
MeSH term(s)	Adult ; Humans ; Air Pollutants/adverse effects ; Air Pollutants/analysis ; Retrospective Studies ; Asthma ; Pulmonary Disease, Chronic Obstructive/chemically induced ; Urolithiasis/chemically induced ; Emergency Service, Hospital
Chemical Substances	Air Pollutants
Language	English
Publishing date	2023-06-30
Publishing country	United States
Document type	Journal Article
ZDB-ID	200515-3
ISSN	1551-4056 ; 0044-0086
ISSN (online)	1551-4056
ISSN	0044-0086
DOI	10.59249/KYDF6093
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