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Article ; Online: Two new species of the genus Macromotettixoides Zheng, Wei & Jiang (Orthoptera: Tetrigidae: Metrodorinae) from China

Wei, Shi-Zhen / Deng, Wei-an

Oriental Insects. 2023 Apr. 03, v. 57, no. 2 p.626-642

2023

Abstract: New species, Macromotettixoides daweishana sp. nov. from Yunnan and Macromotettixoides orthomargina sp. nov. from Sichuan, are described and illustrated. M. daweishana is similar to M. undulatifemura but differs in the shape of pronotum and narrow vertex. ...

Abstract	New species, Macromotettixoides daweishana sp. nov. from Yunnan and Macromotettixoides orthomargina sp. nov. from Sichuan, are described and illustrated. M. daweishana is similar to M. undulatifemura but differs in the shape of pronotum and narrow vertex. M. orthomargina is similar to M. shengtangshanensis but differs in the shape of infrascapular area and the wide vertex. The distribution and a key to the species of Macromotettixoides are given. http://www.zoobank.org/urn:lsid:zoobank.org:pub:38128DB6-2DFB-4C8B-9AD4-6B773B9EA8F3
Keywords	Tetrigidae ; new species ; taxonomic keys ; China ; Tetrigoidea ; pygmy grasshoppers ; taxonomy ; Yunnan ; Sichuan
Language	English
Dates of publication	2023-0403
Size	p. 626-642.
Publishing place	Taylor & Francis
Document type	Article ; Online
ISSN	2157-8745
DOI	10.1080/00305316.2022.2098198
Database	NAL-Catalogue (AGRICOLA)

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Article: Quantifying the superimposed effects of drought-flood abrupt alternation stress on vegetation dynamics of the Wei River Basin in China

Shi, Wuzhi / Huang, Shengzhi / Zhang, Ke / Liu, Bojun / Liu, Dengfeng / Huang, Qiang / Fang, Wei / Han, Zhiming / Chao, Lijun

Journal of hydrology. 2022 June 17,

2022

Abstract: ... The Wei River Basin (WRB), the largest tributary of the Yellow River, was selected as a case study ...

Abstract	Understanding the response mechanism of vegetation growth to hydro-meteorological events is essential at the global or regional scales, especially in context of global warming and anthropogenic interventions. Previous studies have focused mainly on the responses of vegetation vulnerability to single drought or flood extremes but rarely on those of drought-flood abrupt alternation (i.e., coexistence and rapid transformation of drought and flood, DFAA) events on vegetation growth. Here, this study proposed a binary copula evaluation model to quantitatively explore the internal mechanism of vegetation activity response to DFAA events (flood to drought (FTD) and drought to flood (DTF)) from probabilistic perspective. The Wei River Basin (WRB), the largest tributary of the Yellow River, was selected as a case study. Normalized Difference Vegetation Index (NDVI) was used as a proxy to reveal the spatial-temporal dynamics of vegetation coverage. Then, the response time of vegetation vitality to spring-summer and summer-autumn DFAA events was diagnosed. Finally, the conditional possibility of different vegetation states under DFAA stress was examined. Results showed that: (1) the lag time of optional vegetation response to DFAA events was more than 4 months; (2) FTD and DTF showed drought-flood synergism and antagonism by strengthening and weakening single stress, respectively; and (3) the Jing River Basin is an FTD-sensitive area, whereas as a summer-autumn DTF-compensatory area, the decision-makers should control the stress degree of the upper of the WRB to have a favorable impact on vegetation. Generally, this study sheds new insights into vegetation response to DFAA events, which provides effective theoretical support for decision-makers to formulate effective strategies for DFAA mitigation and sustainable development of ecosystems.
Keywords	antagonism ; case studies ; decision making ; drought ; hydrometeorology ; models ; normalized difference vegetation index ; sustainable development ; synergism ; vegetation ; watersheds ; China ; Yellow River
Language	English
Dates of publication	2022-0617
Publishing place	Elsevier B.V.
Document type	Article
Note	Pre-press version
ZDB-ID	1473173-3
ISSN	1879-2707 ; 0022-1694
ISSN (online)	1879-2707
ISSN	0022-1694
DOI	10.1016/j.jhydrol.2022.128105
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Article ; Online: Psychological distance and physical distance induced residents' heterogeneous willingness to pay for transboundary watershed ecosystem services in the Wei River Basin, China.

Shi, Yuxing / Li, Chaoqiong / Zhao, Minjuan / Ni, Qi

Environmental management

2023 Volume 72, Issue 6, Page(s) 1259–1276

Abstract: ... on residents' preference and WTP for the Wei River Basin ESs. The results showed that midstream and downstream ...

Abstract	Under the framework of payment for transboundary watershed ecosystem services (ESs), identifying midstream and downstream residents' preference and willingness to pay (WTP) for ESs provided by the upstream is crucial for sustainable watershed management. The residents' preferences and WTP are not evenly distributed within the watershed. This study uses a choice experiment assessing the spatial impact of physical distance (including residents' watershed location and distance to waterbody) and psychological distance on residents' preference and WTP for the Wei River Basin ESs. The results showed that midstream and downstream residents' preference and WTP for the ecological attributes have a significant distance-decay effect, either the physical distance to the upstream exit or physical and psychological distance to the waterbody. However, compared with the residents in the midstream, the residents downstream have a stronger preference and WTP for upstream ecological governance. Besides, the distance-decay effect differs between urban and rural residents. There is a psychological distance-decay effect in rural residents' preference for water quality and a physical distance-decay effect in their preference for water quantity, entertainment area, and cost; there is a physical distance decay effect in urban residents' preference for entertainment areas. The above differences lead to heterogeneity in WTP and total economic value (TEV) for ESs. When calculating the TEV of the transboundary watershed ES and charging the public, policymakers should consider the location of the residents, the physical and psychological distance to the water body, and the difference between urban and rural areas.
Language	English
Publishing date	2023-07-04
Publishing country	United States
Document type	Journal Article
ZDB-ID	1478932-2
ISSN	1432-1009 ; 0364-152X
ISSN (online)	1432-1009
ISSN	0364-152X
DOI	10.1007/s00267-023-01850-9
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Article ; Online: Chang Wei Qing Decoction enhances the anti-tumor effect of PD-1 inhibitor therapy by regulating the immune microenvironment and gut microbiota in colorectal cancer.

Wang, Ting / Wu, Linguangjin / Wang, Shuyun / Shi, Xiaolan / Liu, Hui / Deng, Wanli

Chinese journal of natural medicines

2023 Volume 21, Issue 5, Page(s) 333–345

Abstract: ... immune microenvironment (TIME). This study aimed to mechanistically assess whether Chang Wei Qing (CWQ ...

Abstract	The anti-tumor effect of anti-PD-1 antibody has long been shown to be strongly related to the tumor immune microenvironment (TIME). This study aimed to mechanistically assess whether Chang Wei Qing (CWQ) Decoction can enhance the anti-tumor effect of PD-1 inhibitor therapy. PD-1 inhibitor therapy showed the significant anti-tumor effect in patients with mismatch repair-deficient/microsatellite instability-high (dMMR/MSI-H) colorectal cancer (CRC), rather than those with mismatch repair-proficient/microsatellite stable (pMMR/MSS) CRC. Hence, immunofluorescence double-label staining was utilized to explore the difference in the TIME between dMMR/MSI-H and pMMR/MSS CRC patients. Flow cytometry was used to analyze T-lymphocytes in tumors from mice. Western blot was used to measure the expression of PD-L1 protein in mouse tumors. The intestinal mucosal barrier of mice was evaluated by hematoxylin-eosin staining and immunohistochemistry. 16S rRNA-gene sequencing was used to examine the structure of the gut microbiota in mice. Subsequently, Spearmanapos;s correlation analysis was used to analyze the relationship between the gut microbiota and tumor-infiltrating T-lymphocytes. The results showed that dMMR/MSI-H CRC patients had more CD8
MeSH term(s)	Animals ; Mice ; Immune Checkpoint Inhibitors/pharmacology ; Immune Checkpoint Inhibitors/therapeutic use ; Gastrointestinal Microbiome ; CD8-Positive T-Lymphocytes ; B7-H1 Antigen ; RNA, Ribosomal, 16S ; Colorectal Neoplasms/metabolism ; Colonic Neoplasms ; Tumor Microenvironment
Chemical Substances	Immune Checkpoint Inhibitors ; B7-H1 Antigen ; RNA, Ribosomal, 16S
Language	English
Publishing date	2023-03-03
Publishing country	China
Document type	Journal Article
ZDB-ID	2192577-X
ISSN	1875-5364 ; 2095-6975 ; 1672-3651
ISSN (online)	1875-5364
ISSN	2095-6975 ; 1672-3651
DOI	10.1016/S1875-5364(23)60451-0
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Article: Investigation into Polycyclic Aromatic Hydrocarbons in Sediments of Wei River Basin

Shi, Yongfeng / Lu, Yuehan / Zhang, Yucheng / Su, Xiaotong / Wu, Qihang / Lei, Huifang / Fang, Linchuan / Zhang, Fengbao / Liu, Zhineng / Han, Jie / Mai, Bixian

Water, air, and soil pollution. 2021 Nov., v. 232, no. 11

2021

Abstract: ... and risk assessment of PAHs in Wei River Basin. It was found that the total concentration (∑₁₆PAHs ... of selected PAHs in sediments for the main stream of Wei River and its tributaries ranged from n.d. (not ... while other compounds were negligible. Total ecological risk of ∑₁₆PAHs posed low to moderate ecological risk in Wei ...

Abstract	Polycyclic aromatic hydrocarbons (PAHs), as indicators of anthropogenic activities, existed in sediments may pose potential risk to environment. In the present study, we assessed occurrence, composition, and risk assessment of PAHs in Wei River Basin. It was found that the total concentration (∑₁₆PAHs) of selected PAHs in sediments for the main stream of Wei River and its tributaries ranged from n.d. (not detectable) to 577.25 ng g⁻¹ and 36.35 to 2348.77 ng g⁻¹, respectively. The PAHs were mostly dominated by PHE and FLT. Based on the diagnostic ratios of FLT/(FLT + PYR), BaA/(BaA + CHR), and PCA analysis, we deducted that diesel emissions and incomplete combustion of petroleum fuels were predominant in the selected area. For sediment quality guidelines (SQGs), adverse effects of three PAHs (ACE, PHE, and BgP) in sediment were occasionally observed, while the other 9 PAHs were considered to occur rarely. The total carcinogenicity of PAHs assessed by TEQBₐP ranged from n.d. to 138.84 ng g⁻¹, and BaP played the dominant role. The ecological risk of individual PAHs (ACE, FLU, PHE, FLT, PYR, BaA, BbF, BaP) were moderate, while other compounds were negligible. Total ecological risk of ∑₁₆PAHs posed low to moderate ecological risk in Wei River Basin.
Keywords	air ; carcinogenicity ; combustion ; petroleum ; risk ; risk assessment ; rivers ; sediments ; soil pollution ; water ; watersheds
Language	English
Dates of publication	2021-11
Size	p. 476.
Publishing place	Springer International Publishing
Document type	Article
ZDB-ID	120499-3
ISSN	1573-2932 ; 0049-6979 ; 0043-1168
ISSN (online)	1573-2932
ISSN	0049-6979 ; 0043-1168
DOI	10.1007/s11270-021-05403-w
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Article ; Online: Chang Wei Qing Decoction enhances the anti-tumor effect of PD-1 inhibitor therapy by regulating the immune microenvironment and gut microbiota in colorectal cancer

Wang, Ting / WU, Linguangjin / Wang, Shuyun / SHI, Xiaolan / Liu, Hui / DENG, Wanli

Chinese Journal of Natural Medicines. 2023 May, v. 21, no. 5 p.333-345

2023

Abstract: ... immune microenvironment (TIME). This study aimed to mechanistically assess whether Chang Wei Qing (CWQ ...

Abstract	The anti-tumor effect of anti-PD-1 antibody has long been shown to be strongly related to the tumor immune microenvironment (TIME). This study aimed to mechanistically assess whether Chang Wei Qing (CWQ) Decoction can enhance the anti-tumor effect of PD-1 inhibitor therapy. PD-1 inhibitor therapy showed the significant anti-tumor effect in patients with mismatch repair-deficient/microsatellite instability-high (dMMR/MSI-H) colorectal cancer (CRC), rather than those with mismatch repair-proficient/microsatellite stable (pMMR/MSS) CRC. Hence, immunofluorescence double-label staining was utilized to explore the difference in the TIME between dMMR/MSI-H and pMMR/MSS CRC patients. Flow cytometry was used to analyze T-lymphocytes in tumors from mice. Western blot was used to measure the expression of PD-L1 protein in mouse tumors. The intestinal mucosal barrier of mice was evaluated by hematoxylin-eosin staining and immunohistochemistry. 16S rRNA-gene sequencing was used to examine the structure of the gut microbiota in mice. Subsequently, Spearmanapos;s correlation analysis was used to analyze the relationship between the gut microbiota and tumor-infiltrating T-lymphocytes. The results showed that dMMR/MSI-H CRC patients had more CD8⁺T cells and higher expression of PD-1 and PD-L1 proteins. In vivo, CWQ enhanced the anti-tumor effect of anti-PD-1 antibody and increased the infiltration of CD8⁺ and PD-1⁺CD8⁺ T cells in tumors. Additionally, the combination of CWQ with anti-PD-1 antibody resulted in lower inflammation in the intestinal mucosa than that induced by anti-PD-1 antibody alone. CWQ and anti-PD-1 antibody co-treatment upregulated PD-L1 protein and reduced the abundance of Bacteroides in the gut microbiota but increased the abundance of Akkermansia,Firmicutes, andActinobacteria. Additionally, the proportion of infiltrated CD8⁺PD-1⁺, CD8⁺, and CD3⁺ T cells were found to be positively correlated with the abundance of Akkermansia. Accordingly, CWQ may modulate the TIME by modifying the gut microbiota and consequently enhance the anti-tumor effect of PD-1 inhibitor therapy.
Keywords	Bacteroides ; T-lymphocytes ; Western blotting ; antibodies ; antineoplastic activity ; colorectal neoplasms ; flow cytometry ; fluorescent antibody technique ; immunohistochemistry ; inflammation ; intestinal microorganisms ; intestinal mucosa ; mice ; therapeutics ; Tumor immune microenvironment ; PD-1 inhibitor therapy ; Gut microbiota ; CD8+ T cells ; Chang Wei Qing
Language	English
Dates of publication	2023-05
Size	p. 333-345.
Publishing place	Elsevier B.V.
Document type	Article ; Online
ZDB-ID	2192577-X
ISSN	1875-5364 ; 2095-6975 ; 1672-3651
ISSN (online)	1875-5364
ISSN	2095-6975 ; 1672-3651
DOI	10.1016/S1875-5364(23)60451-0
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Article: [A multicenter randomized controlled study of bismuth-containing quadruple therapy followed by Jing-Hua-Wei-Kang in the treatment of patients newly diagnosed with

Ma, P P / Meng, L N / Wang, M T / Jin, H F / Fan, Y H / Zha, A S / Huo, X H / Chen, D F / Cao, Z Q / Tang, X F / Yang, P / Shi, Z H / Li, T W / Meng, J / Gan, C / Chen, G X / Sha, W H / Du, Q / Li, Y /

Lyu, B

Zhonghua yi xue za zhi

2021 Volume 101, Issue 26, Page(s) 2060–2065

Abstract: Objective: ...

Abstract	Objective:
MeSH term(s)	Amoxicillin/therapeutic use ; Anti-Bacterial Agents/therapeutic use ; Bismuth/therapeutic use ; China ; Drug Therapy, Combination ; Dyspepsia/drug therapy ; Female ; Helicobacter Infections/drug therapy ; Helicobacter pylori ; Humans ; Male ; Middle Aged ; Treatment Outcome
Chemical Substances	Anti-Bacterial Agents ; Amoxicillin (804826J2HU) ; Bismuth (U015TT5I8H)
Language	Chinese
Publishing date	2021-07-18
Publishing country	China
Document type	Journal Article ; Multicenter Study ; Randomized Controlled Trial
ZDB-ID	132513-9
ISSN	0376-2491
ISSN	0376-2491
DOI	10.3760/cma.j.cn112137-20210305-00563
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Article ; Online: Network pharmacology and experiments in vivo and in vitro reveal that the Jia-Wei-Bu-Shen-Yi-Qi formula (JWBSYQF) and its active ingredient baicalein ameliorate BLM-induced lung fibrosis in mice via PI3K/Akt signaling pathway.

Shi, Hanlin / Deng, Lingling / Zhou, Yaolong / Yu, Hang / Huang, Xi / Chen, Mengmeng / Lei, Yang / Dong, Jingcheng

Journal of ethnopharmacology

2023 Volume 315, Page(s) 116691

Abstract: Ethnopharmacological relevance: Jia-Wei-Bu-Shen-Yi-Qi formula (JWBSYQF), a classical traditional ...

Abstract	Ethnopharmacological relevance: Jia-Wei-Bu-Shen-Yi-Qi formula (JWBSYQF), a classical traditional Chinese herbal formula consisting of five herbs, is used clinically in China to treat inflammatory lung diseases, including asthma, chronic obstructive pulmonary disease (COPD) and idiopathic pulmonary fibrosis (IPF). Its mechanism for treating asthma and COPD has been reported, however, how it works against IPF remains unclear. Research purpose: Our study aims to observe the therapeutic effect of JWBSYQF on pulmonary fibrosis and further identify the potential active ingredients and molecular pathways. Research methods: In this study, we used a bleomycin-induced mouse model to investigate the therapeutic effect of JWBSYQF on pulmonary fibrosis. To further explore the potential effective ingredients and molecular pathways, we used the network pharmacology approach to construct a drug-ingredient-target network of JWBSYQF. Then, the common target set was established for JWBSYQF, fibroblast, and lung fibrosis. Analyses of the KEGG pathway, GO enrichment, and network topology were performed to identify key biological processes and molecular pathways for the common targets. Finally, a TGF-β-induced NIH/3T3 proliferation and activation model was used to validate the possible active ingredients and signaling pathways. Research results: JWBSYQF reversed BLM-induced balf leukocyte levels, pulmonary inflammatory lesions and fibrotic collagen deposition in mice and reduced the levels of a-SMA, Col1a1 and TGF-β. A total of 86 active ingredients were identified, 12 of which were considered as potential effective ingredients, while only baicalein effectively improved TGF-β-induced proliferation and activation of NIH/3T3. KEGG results showed that PI3K/Akt signaling pathway may be the potential action mechanism, and Western Blot demonstrated that both JWBSYQF and baicalein downregulated the protein levels of p-PI3K and p-Akt. The molecular docking results suggest that baicalein may have a direct effect on the catalytic and regulatory subunits of P13K, which is stronger than direct binding to Aktl. Conclusions: Our study revealed that baicalein may be the material basis for JWBSYQF in the treatment of pulmonary fibrosis, and the PI3K/Akt signaling pathway may be a common pathway of action for JWBSYQF and baicalein.
MeSH term(s)	Animals ; Mice ; Phosphatidylinositol 3-Kinases ; Proto-Oncogene Proteins c-akt ; Network Pharmacology ; Molecular Docking Simulation ; Idiopathic Pulmonary Fibrosis ; Asthma ; Pulmonary Disease, Chronic Obstructive ; Signal Transduction ; Drugs, Chinese Herbal/pharmacology ; Drugs, Chinese Herbal/therapeutic use
Chemical Substances	baicalein (49QAH60606) ; Phosphatidylinositol 3-Kinases (EC 2.7.1.-) ; Proto-Oncogene Proteins c-akt (EC 2.7.11.1) ; Drugs, Chinese Herbal
Language	English
Publishing date	2023-05-27
Publishing country	Ireland
Document type	Journal Article
ZDB-ID	134511-4
ISSN	1872-7573 ; 0378-8741
ISSN (online)	1872-7573
ISSN	0378-8741
DOI	10.1016/j.jep.2023.116691
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Article: CCl4‐Enhanced Ultrasonic Irradiation for Ciprofloxacin Degradation and Antibiotic Activity: Wei et al

Wei, Hong / Shi, Jingzhuan / Yang, Xiaoyu / Wang, Jiawei / Li, Kebin / He, Qiang

Water environment research. 2018 July, v. 90, no. 7

2018

Abstract: In this study, an ultrasound/CCl₄ system was used to degrade the fluoroquinolone antibiotic, ciprofloxacin, in aqueous solution. The effect of CCl₄ concentration and initial solution pH on ciprofloxacin degradation were investigated. The results showed ... ...

Abstract	In this study, an ultrasound/CCl₄ system was used to degrade the fluoroquinolone antibiotic, ciprofloxacin, in aqueous solution. The effect of CCl₄ concentration and initial solution pH on ciprofloxacin degradation were investigated. The results showed that ciprofloxacin degraded effectively under an ultrasound/CCl₄ system, with degradation efficiency increasing from 0.51% to 50.92%, when the CCl₄ concentration ranged from 0.0 to 41.4 mmol/L in 40 min. Radical scavenging experiments certified that both •OH and chlorine‐containing radicals contributed to ciprofloxacin degradation. Eight intermediates were detected using ultra high‐performance liquid chromatography‐mass spectrometry (UHPLC‐MS) method, including three chloro‐intermediates. Based on these results, the possible degradation pathways of ciprofloxacin are proposed. Agar diffusion tests with E. coli and S. aureus showed that ciprofloxacin's antibacterial activity was completely removed in 40 min. This study indicates that an ultrasound/CCl₄ system can degrade ciprofloxacin and remove its antibacterial activity, and thus is a promising process for treating fluoroquinolone antibiotics in wastewater.
Keywords	Escherichia coli ; agar ; antibacterial properties ; antibiotics ; aqueous solutions ; ciprofloxacin ; environment ; mass spectrometry ; pH ; research ; ultrasonic treatment ; wastewater ; water
Language	English
Dates of publication	2018-07
Size	p. 579-588.
Publishing place	Water Environment Federation
Document type	Article
Note	JOURNAL ARTICLE
ZDB-ID	1098976-6
ISSN	1554-7531 ; 1047-7624 ; 1061-4303
ISSN (online)	1554-7531
ISSN	1047-7624 ; 1061-4303
DOI	10.2175/106143017X15131012153077
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Article: [Professor Wei Pin-kang's experience in treating chemotherapy induced nausea and vomiting: an analysis of herbal medication].

Shi, Jun / Wei, Pin-Kang

Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine

2012 Volume 32, Issue 4, Page(s) 556–9, 571

Abstract: Objective: To summarize the herbal medication by Professor WEI Pin-kang's prescriptions ... distribution was 6 627 and these herbs were mostly attributed to Pi, Wei, Gan, and Fei meridians (CRF 71.34 ... ossis mastodi and oyster, large head atractylodes and poria, and so on.: Conclusions: Professor WEI ...

Abstract	Objective: To summarize the herbal medication by Professor WEI Pin-kang's prescriptions in treating chemotherapy induced nausea and vomiting (CINV). Methods: On the basis of outpatient and inpatients' medical records concerning CINV from case-database (keywords: chemotherapy and vomiting), data of 143 patients and 143 effective prescriptions were collected. The herbs and those category, nature, flavor and meridian distribution were summarized by frequency method using SPSS 13.0 Software. The couple herbs were analyzed by hierarchical cluster analysis. Results: A total of 144 herbs were used (2 353 frequencies). Six groups of herbs [ frequency >5%, cumulative relative frequency (CRF) 58.89%] were used frequently as follow: the herbs for regulating qi (17.81%), resolving phlegm (13.51%), invigorating qi (8.07%), relieving food retention (7.44%), calming Gan to stop endogenous wind (7.05%), and warming the interior (5.01%). The most frequently used herbs ( >20 frequencies, CRF 77.31%) had 31 species as follow: the herbs for regulating qi (6 species), calming Gan to stop endogenous wind (4 species), resolving phlegm (3 species), external application (2 species), invigorating qi (2 species), warming the interior (2 species), activating blood and removing blood stasis (2 species), promoting diuresis and resolving dampness (1 species), purgation (1 species), invigorating blood (1 species), relieving exterior syndrome with pungent-warm property (1 species), relieving exterior syndrome with pungent-cool property (1 species), astringent (1 species), resolving dampness with aromatic property (1 species), calming the mind (1 species), eliminating heat and dampness (1 species), relieving food retention (1 species). Frequency of Rhizoma Pinelliae was 127 including Rhizoma Pinelliae (processed with ginger) 83 (65.35%). Frequency of prepared Radix et Rhizoma Rhei was 85 (95.51% of Prea- praed Rhizoma Rhei). These herbs were mostly of warm nature (43.99%). The total frequency of herb-nature was 3 677 and the pungent (34.76%), bitter (32.06%) and sweet herbs (18.22%) were most frequently used (CRF 85.04%). The total frequency of meridian distribution was 6 627 and these herbs were mostly attributed to Pi, Wei, Gan, and Fei meridians (CRF 71.34%). The most frequently used couple-herbs included Rhizoma Pinelliae and Rhizoma Atisaematis, Fructus Aurantii Immaturus and Submature Bitter Orange, Flos Caryophylli and Calyx Kaki, Rhizoma Coptidis and Os Sepiae, Rumulus Ginnamomi and Radix Paeoniae, Fructus Citri Sarcodactylis and Fructus Citri, aloeswood and toad skin, scorpion and centipede, earth worm and Gekko Swinhoana, bupleurum root and curcumae, fossilia ossis mastodi and oyster, large head atractylodes and poria, and so on. Conclusions: Professor WEI Pin-kang regarded the therapy of dissolving phlegm and regulating Wei as the fundamental treatment of CINV. He emphasized gastrointestinal metabolic disorders induced by phlegm and stagnation related to chemotherapeutics. He laid equal emphasis on regulating qi, dissolving phlegm, and removing stagnation.
MeSH term(s)	Antineoplastic Combined Chemotherapy Protocols/adverse effects ; Drugs, Chinese Herbal/administration & dosage ; Drugs, Chinese Herbal/therapeutic use ; Humans ; Medicine, Chinese Traditional/methods ; Nausea/chemically induced ; Nausea/drug therapy ; Phytotherapy/methods ; Vomiting/chemically induced ; Vomiting/drug therapy
Chemical Substances	Drugs, Chinese Herbal
Language	Chinese
Publishing date	2012-04
Publishing country	China
Document type	English Abstract ; Journal Article
ZDB-ID	1195456-5
ISSN	1003-5370
ISSN	1003-5370
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